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8WI0

wt-hMRP5 inward-open

Functional Information from GO Data
ChainGOidnamespacecontents
A0005524molecular_functionATP binding
A0005768cellular_componentendosome
A0005794cellular_componentGolgi apparatus
A0005796cellular_componentGolgi lumen
A0005886cellular_componentplasma membrane
A0006805biological_processxenobiotic metabolic process
A0006855biological_processxenobiotic transmembrane transport
A0008514molecular_functionorganic anion transmembrane transporter activity
A0008559molecular_functionABC-type xenobiotic transporter activity
A0010008cellular_componentendosome membrane
A0015216molecular_functionpurine nucleotide transmembrane transporter activity
A0015232molecular_functionheme transmembrane transporter activity
A0015562molecular_functionefflux transmembrane transporter activity
A0015865biological_processpurine nucleotide transport
A0016020cellular_componentmembrane
A0016323cellular_componentbasolateral plasma membrane
A0016324cellular_componentapical plasma membrane
A0022884molecular_functionmacromolecule transmembrane transporter activity
A0030213biological_processhyaluronan biosynthetic process
A0034634molecular_functionglutathione transmembrane transporter activity
A0034775biological_processglutathione transmembrane transport
A0035351biological_processheme transmembrane transport
A0042626molecular_functionATPase-coupled transmembrane transporter activity
A0042908biological_processxenobiotic transport
A0042910molecular_functionxenobiotic transmembrane transporter activity
A0043225molecular_functionATPase-coupled inorganic anion transmembrane transporter activity
A0055085biological_processtransmembrane transport
A0070730biological_processcAMP transport
A0070731biological_processcGMP transport
A0098656biological_processmonoatomic anion transmembrane transport
A0098838biological_processfolate transmembrane transport
A0140115biological_processexport across plasma membrane
A0140359molecular_functionABC-type transporter activity
A0150104biological_processtransport across blood-brain barrier
A1901505molecular_functioncarbohydrate derivative transmembrane transporter activity
Functional Information from PROSITE/UniProt
site_idPS00211
Number of Residues15
DetailsABC_TRANSPORTER_1 ABC transporters family signature. LSGGQRQRISLARAL
ChainResidueDetails
ALEU685-LEU699
APHE1330-LEU1344

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
BSEP60
AVAL997-ALA1017
AVAL1018-GLU1038
ALEU1104-ILE1124
AALA1127-VAL1147
ALEU219-THR239
ALEU296-GLY316
APRO317-SER337
ASER400-VAL420
APHE434-VAL454
AILE608-VAL628
AVAL848-LEU868
AILE917-VAL937

site_idSWS_FT_FI2
Number of Residues2
DetailsBINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00434
ChainResidueDetails
AGLY595
AGLY1227

site_idSWS_FT_FI3
Number of Residues4
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
ASER14
ASER19
ASER60
ASER505

site_idSWS_FT_FI4
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163
ChainResidueDetails
ASER509

site_idSWS_FT_FI5
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648
ChainResidueDetails
ATHR513

site_idSWS_FT_FI6
Number of Residues8
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
AASN494
AASN636
AASN684
AASN890
AASN897
AASN1044
AASN1329
AASN1417

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PDB entries from 2024-10-30

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