Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

8WHY

Cryo- EM structure of Mycobacterium smegmatis 50S ribosomal subunit (body 1) of 70S ribosome and RafH.

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0003735	molecular_function	structural constituent of ribosome
1	0005840	cellular_component	ribosome
1	0006412	biological_process	translation
2	0003735	molecular_function	structural constituent of ribosome
2	0005840	cellular_component	ribosome
2	0006412	biological_process	translation
2	0022625	cellular_component	cytosolic large ribosomal subunit
3	0003735	molecular_function	structural constituent of ribosome
3	0006412	biological_process	translation
3	0015934	cellular_component	large ribosomal subunit
3	0022625	cellular_component	cytosolic large ribosomal subunit
4	0003735	molecular_function	structural constituent of ribosome
4	0005840	cellular_component	ribosome
4	0006412	biological_process	translation
5	0003735	molecular_function	structural constituent of ribosome
5	0006412	biological_process	translation
5	0015934	cellular_component	large ribosomal subunit
6	0003735	molecular_function	structural constituent of ribosome
6	0005737	cellular_component	cytoplasm
6	0005840	cellular_component	ribosome
6	0006412	biological_process	translation
7	0003735	molecular_function	structural constituent of ribosome
7	0005840	cellular_component	ribosome
7	0006412	biological_process	translation
8	0003735	molecular_function	structural constituent of ribosome
8	0005840	cellular_component	ribosome
8	0006412	biological_process	translation
8	0015934	cellular_component	large ribosomal subunit
8	0022625	cellular_component	cytosolic large ribosomal subunit
E	0002181	biological_process	cytoplasmic translation
E	0003723	molecular_function	RNA binding
E	0003735	molecular_function	structural constituent of ribosome
E	0005840	cellular_component	ribosome
E	0006412	biological_process	translation
E	0015934	cellular_component	large ribosomal subunit
E	0016740	molecular_function	transferase activity
E	0019843	molecular_function	rRNA binding
F	0003735	molecular_function	structural constituent of ribosome
F	0005840	cellular_component	ribosome
F	0006412	biological_process	translation
F	0019843	molecular_function	rRNA binding
F	0022625	cellular_component	cytosolic large ribosomal subunit
G	0003735	molecular_function	structural constituent of ribosome
G	0005840	cellular_component	ribosome
G	0006412	biological_process	translation
G	0019843	molecular_function	rRNA binding
H	0000049	molecular_function	tRNA binding
H	0003735	molecular_function	structural constituent of ribosome
H	0005840	cellular_component	ribosome
H	0006412	biological_process	translation
H	0019843	molecular_function	rRNA binding
I	0002181	biological_process	cytoplasmic translation
I	0003723	molecular_function	RNA binding
I	0003735	molecular_function	structural constituent of ribosome
I	0005840	cellular_component	ribosome
I	0006412	biological_process	translation
I	0019843	molecular_function	rRNA binding
I	0022625	cellular_component	cytosolic large ribosomal subunit
J	0003735	molecular_function	structural constituent of ribosome
J	0005840	cellular_component	ribosome
J	0006412	biological_process	translation
J	0019843	molecular_function	rRNA binding
M	0003729	molecular_function	mRNA binding
M	0003735	molecular_function	structural constituent of ribosome
M	0005840	cellular_component	ribosome
M	0006412	biological_process	translation
M	0017148	biological_process	negative regulation of translation
M	0022625	cellular_component	cytosolic large ribosomal subunit
N	0003735	molecular_function	structural constituent of ribosome
N	0005840	cellular_component	ribosome
N	0006412	biological_process	translation
N	0015934	cellular_component	large ribosomal subunit
N	0019843	molecular_function	rRNA binding
N	0022625	cellular_component	cytosolic large ribosomal subunit
N	0070180	molecular_function	large ribosomal subunit rRNA binding
O	0003735	molecular_function	structural constituent of ribosome
O	0005840	cellular_component	ribosome
O	0006412	biological_process	translation
O	0015934	cellular_component	large ribosomal subunit
O	0019843	molecular_function	rRNA binding
O	0022625	cellular_component	cytosolic large ribosomal subunit
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005840	cellular_component	ribosome
Q	0006412	biological_process	translation
Q	0015934	cellular_component	large ribosomal subunit
Q	0022625	cellular_component	cytosolic large ribosomal subunit
R	0003735	molecular_function	structural constituent of ribosome
R	0005737	cellular_component	cytoplasm
R	0005840	cellular_component	ribosome
R	0006412	biological_process	translation
R	0008097	molecular_function	5S rRNA binding
R	0019843	molecular_function	rRNA binding
R	0022625	cellular_component	cytosolic large ribosomal subunit
S	0003735	molecular_function	structural constituent of ribosome
S	0005840	cellular_component	ribosome
S	0006412	biological_process	translation
S	0022625	cellular_component	cytosolic large ribosomal subunit
T	0000027	biological_process	ribosomal large subunit assembly
T	0003735	molecular_function	structural constituent of ribosome
T	0005840	cellular_component	ribosome
T	0006412	biological_process	translation
T	0019843	molecular_function	rRNA binding
U	0003723	molecular_function	RNA binding
U	0003735	molecular_function	structural constituent of ribosome
U	0005737	cellular_component	cytoplasm
U	0005840	cellular_component	ribosome
U	0006412	biological_process	translation
U	0019843	molecular_function	rRNA binding
V	0003735	molecular_function	structural constituent of ribosome
V	0005840	cellular_component	ribosome
V	0006412	biological_process	translation
V	0015934	cellular_component	large ribosomal subunit
V	0019843	molecular_function	rRNA binding
V	0022625	cellular_component	cytosolic large ribosomal subunit
W	0003735	molecular_function	structural constituent of ribosome
W	0005840	cellular_component	ribosome
W	0006412	biological_process	translation
W	0019843	molecular_function	rRNA binding
X	0003723	molecular_function	RNA binding
X	0003735	molecular_function	structural constituent of ribosome
X	0005840	cellular_component	ribosome
X	0006412	biological_process	translation
X	0019843	molecular_function	rRNA binding
Z	0003735	molecular_function	structural constituent of ribosome
Z	0005840	cellular_component	ribosome
Z	0006412	biological_process	translation
Z	0022625	cellular_component	cytosolic large ribosomal subunit

Functional Information from PROSITE/UniProt

site_id	PS00049
Number of Residues	27
Details	RIBOSOMAL_L14 Ribosomal protein L14 signature. AVVVrtvkerrra.DGsyikFdeNaaVI

Chain	Residue	Details
N	ALA60-ILE86

site_id	PS00050
Number of Residues	16
Details	RIBOSOMAL_L23 Ribosomal protein L23 signature. KRAIVKLAagskpidL

Chain	Residue	Details
W	LYS80-LEU95

site_id	PS00464
Number of Residues	25
Details	RIBOSOMAL_L22 Ribosomal protein L22 signature. KriRpRAqGRafrirkrtSHITViV

Chain	Residue	Details
V	LYS90-VAL114

site_id	PS00467
Number of Residues	12
Details	RIBOSOMAL_L2 Ribosomal protein L2 signature. PtvRGVVmNPvD

Chain	Residue	Details
E	PRO219-ASP230

site_id	PS00474
Number of Residues	24
Details	RIBOSOMAL_L3 Ribosomal protein L3 signature. FsdgayvDvtGtSkGKGfaGtmkR

Chain	Residue	Details
F	PHE106-ARG129

site_id	PS00475
Number of Residues	31
Details	RIBOSOMAL_L15 Ribosomal protein L15 signature. KVLGdGkLtvk..VdVtankFSgsAreaItaaG

Chain	Residue	Details
O	LYS111-GLY141

site_id	PS00525
Number of Residues	9
Details	RIBOSOMAL_L6_1 Ribosomal protein L6 signature 1. PDpYKGKGV

Chain	Residue	Details
I	PRO155-VAL163

site_id	PS00579
Number of Residues	15
Details	RIBOSOMAL_L29 Ribosomal protein L29 signature. NNRRLRtVRQEIARV

Chain	Residue	Details
2	ASN43-VAL57

site_id	PS00582
Number of Residues	20
Details	RIBOSOMAL_L33 Ribosomal protein L33 signature. YiTkKNrrndPdrLEikKFC

Chain	Residue	Details
6	TYR23-CYS42

site_id	PS00634
Number of Residues	33
Details	RIBOSOMAL_L30 Ribosomal protein L30 signature. SLrtLgLkKirQsVvrednaqtrgLIntVhhLV

Chain	Residue	Details
3	SER22-VAL54

site_id	PS00651
Number of Residues	28
Details	RIBOSOMAL_L9 Ribosomal protein L9 signature. GaaGdtveVkdGYgrNYLlprglAivaS

Chain	Residue	Details
J	GLY13-SER40

site_id	PS00784
Number of Residues	20
Details	RIBOSOMAL_L34 Ribosomal protein L34 signature. KRTFQpnnrrRarvh.GFrlR

Chain	Residue	Details
7	LYS5-ARG24

site_id	PS00831
Number of Residues	15
Details	RIBOSOMAL_L27 Ribosomal protein L27 signature. GeILvRQRGthfhpG

Chain	Residue	Details
Z	GLY34-GLY48

site_id	PS00936
Number of Residues	27
Details	RIBOSOMAL_L35 Ribosomal protein L35 signature. KTHsGAsKRFrrtgtgkivrqkanr.RH

Chain	Residue	Details
8	LYS5-HIS31

site_id	PS00937
Number of Residues	17
Details	RIBOSOMAL_L20 Ribosomal protein L20 signature. KgefRkLWISRINaaaR

Chain	Residue	Details
T	LYS54-ARG70

site_id	PS01015
Number of Residues	16
Details	RIBOSOMAL_L19 Ribosomal protein L19 signature. VlTrGDVR.RAKLYYLR

Chain	Residue	Details
S	VAL85-ARG100

site_id	PS01108
Number of Residues	18
Details	RIBOSOMAL_L24 Ribosomal protein L24 signature. GDtVlVIsGkdKGak.GkV

Chain	Residue	Details
X	GLY6-VAL23

site_id	PS01143
Number of Residues	22
Details	RIBOSOMAL_L31 Ribosomal protein L31 signature. EVcsqcHPFYTgkqkildsg....GR

Chain	Residue	Details
4	GLU36-ARG57

site_id	PS01167
Number of Residues	23
Details	RIBOSOMAL_L17 Ribosomal protein L17 signature. IkTTepKaRalrpyaEkLIThAK

Chain	Residue	Details
Q	ILE34-LYS56

site_id	PS01169
Number of Residues	23
Details	RIBOSOMAL_L21 Ribosomal protein L21 signature. IrihKfknKTgyhkrqGHRQqlT

Chain	Residue	Details
U	ILE73-THR95

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	90
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	21
Details	Compositional bias: {"description":"Basic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	15
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	10
Details	Compositional bias: {"description":"Polar residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00501","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)