8W5J

Cryo-EM structure of the yeast TOM core complex (from TOM-TIM23 complex)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005739	cellular_component	mitochondrion
A	0005741	cellular_component	mitochondrial outer membrane
A	0005742	cellular_component	mitochondrial outer membrane translocase complex
A	0005758	cellular_component	mitochondrial intermembrane space
A	0005829	cellular_component	cytosol
A	0006811	biological_process	monoatomic ion transport
A	0008320	molecular_function	protein transmembrane transporter activity
A	0015031	biological_process	protein transport
A	0015288	molecular_function	porin activity
A	0030150	biological_process	protein import into mitochondrial matrix
A	0045040	biological_process	protein insertion into mitochondrial outer membrane
A	0046930	cellular_component	pore complex
A	0055085	biological_process	transmembrane transport
B	0005515	molecular_function	protein binding
B	0005739	cellular_component	mitochondrion
B	0005741	cellular_component	mitochondrial outer membrane
B	0005742	cellular_component	mitochondrial outer membrane translocase complex
B	0006886	biological_process	intracellular protein transport
B	0008320	molecular_function	protein transmembrane transporter activity
B	0015031	biological_process	protein transport
B	0030150	biological_process	protein import into mitochondrial matrix
B	0045040	biological_process	protein insertion into mitochondrial outer membrane
C	0005515	molecular_function	protein binding
C	0005739	cellular_component	mitochondrion
C	0005741	cellular_component	mitochondrial outer membrane
C	0005742	cellular_component	mitochondrial outer membrane translocase complex
C	0006626	biological_process	protein targeting to mitochondrion
C	0008320	molecular_function	protein transmembrane transporter activity
C	0015031	biological_process	protein transport
C	0045040	biological_process	protein insertion into mitochondrial outer membrane
C	0070096	biological_process	mitochondrial outer membrane translocase complex assembly
C	0071806	biological_process	protein transmembrane transport
D	0005739	cellular_component	mitochondrion
D	0005741	cellular_component	mitochondrial outer membrane
D	0005742	cellular_component	mitochondrial outer membrane translocase complex
D	0008320	molecular_function	protein transmembrane transporter activity
D	0015031	biological_process	protein transport
D	0030150	biological_process	protein import into mitochondrial matrix
D	0045040	biological_process	protein insertion into mitochondrial outer membrane
D	0070096	biological_process	mitochondrial outer membrane translocase complex assembly
E	0005739	cellular_component	mitochondrion
E	0005741	cellular_component	mitochondrial outer membrane
E	0005742	cellular_component	mitochondrial outer membrane translocase complex
E	0008320	molecular_function	protein transmembrane transporter activity
E	0015031	biological_process	protein transport
E	0030150	biological_process	protein import into mitochondrial matrix
E	0045040	biological_process	protein insertion into mitochondrial outer membrane
I	0005515	molecular_function	protein binding
I	0005739	cellular_component	mitochondrion
I	0005741	cellular_component	mitochondrial outer membrane
I	0005742	cellular_component	mitochondrial outer membrane translocase complex
I	0005758	cellular_component	mitochondrial intermembrane space
I	0005829	cellular_component	cytosol
I	0006811	biological_process	monoatomic ion transport
I	0008320	molecular_function	protein transmembrane transporter activity
I	0015031	biological_process	protein transport
I	0015288	molecular_function	porin activity
I	0030150	biological_process	protein import into mitochondrial matrix
I	0045040	biological_process	protein insertion into mitochondrial outer membrane
I	0046930	cellular_component	pore complex
I	0055085	biological_process	transmembrane transport
J	0005515	molecular_function	protein binding
J	0005739	cellular_component	mitochondrion
J	0005741	cellular_component	mitochondrial outer membrane
J	0005742	cellular_component	mitochondrial outer membrane translocase complex
J	0006886	biological_process	intracellular protein transport
J	0008320	molecular_function	protein transmembrane transporter activity
J	0015031	biological_process	protein transport
J	0030150	biological_process	protein import into mitochondrial matrix
J	0045040	biological_process	protein insertion into mitochondrial outer membrane
K	0005515	molecular_function	protein binding
K	0005739	cellular_component	mitochondrion
K	0005741	cellular_component	mitochondrial outer membrane
K	0005742	cellular_component	mitochondrial outer membrane translocase complex
K	0006626	biological_process	protein targeting to mitochondrion
K	0008320	molecular_function	protein transmembrane transporter activity
K	0015031	biological_process	protein transport
K	0045040	biological_process	protein insertion into mitochondrial outer membrane
K	0070096	biological_process	mitochondrial outer membrane translocase complex assembly
K	0071806	biological_process	protein transmembrane transport
L	0005739	cellular_component	mitochondrion
L	0005741	cellular_component	mitochondrial outer membrane
L	0005742	cellular_component	mitochondrial outer membrane translocase complex
L	0008320	molecular_function	protein transmembrane transporter activity
L	0015031	biological_process	protein transport
L	0030150	biological_process	protein import into mitochondrial matrix
L	0045040	biological_process	protein insertion into mitochondrial outer membrane
L	0070096	biological_process	mitochondrial outer membrane translocase complex assembly
M	0005739	cellular_component	mitochondrion
M	0005741	cellular_component	mitochondrial outer membrane
M	0005742	cellular_component	mitochondrial outer membrane translocase complex
M	0008320	molecular_function	protein transmembrane transporter activity
M	0015031	biological_process	protein transport
M	0030150	biological_process	protein import into mitochondrial matrix
M	0045040	biological_process	protein insertion into mitochondrial outer membrane

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	34
Details	TOPO_DOM: Cytoplasmic => ECO:0000250

Chain	Residue	Details
E	SER2-LYS19
M	SER2-LYS19

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site_id	SWS_FT_FI2
Number of Residues	42
Details	TRANSMEM: Helical => ECO:0000255

Chain	Residue	Details
E	ILE20-TRP41
M	ILE20-TRP41

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site_id	SWS_FT_FI3
Number of Residues	36
Details	TOPO_DOM: Mitochondrial intermembrane => ECO:0000250

Chain	Residue	Details
E	ALA42-VAL60
M	ALA42-VAL60

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site_id	SWS_FT_FI4
Number of Residues	2
Details	MOD_RES: N-acetylmethionine => ECO:0007744|PubMed:22814378

Chain	Residue	Details
D	MET1
L	MET1
J	SER44
J	SER46

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