8W30
Crystal structure of alpha-V beta-1 integrin headpiece in complex with TR01225179
This is a non-PDB format compatible entry.
Functional Information from GO Data
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | BINDING: in MIDAS binding site => ECO:0000269|PubMed:22451694, ECO:0000269|PubMed:33962943, ECO:0007744|PDB:3VI3, ECO:0007744|PDB:3VI4, ECO:0007744|PDB:7NXD |
| Chain | Residue | Details |
| B | SER132 | |
| A | ASP292 | |
| A | ASP349 | |
| A | ASP351 | |
| A | ASP353 | |
| A | PHE355 | |
| A | ASP357 | |
| A | ASP413 | |
| A | ASP415 | |
| A | ASN417 | |
| A | TYR419 | |
| B | GLU229 | |
| A | ASP421 | |
| A | ASP234 | |
| A | ILE236 | |
| A | ASP238 | |
| A | ASP284 | |
| A | ASN286 | |
| A | ASP288 | |
| A | TYR290 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: in MIDAS binding site => ECO:0000269|PubMed:22451694, ECO:0007744|PDB:3VI4 |
| Chain | Residue | Details |
| B | SER134 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | BINDING: in ADMIDAS binding site => ECO:0000269|PubMed:22451694, ECO:0000269|PubMed:33962943, ECO:0007744|PDB:3VI3, ECO:0007744|PDB:7NXD |
| Chain | Residue | Details |
| B | ASP137 | |
| B | ASP138 | |
| B | ALA342 | |
| A | ASN524 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | BINDING: in LIMBS binding site => ECO:0000269|PubMed:22451694, ECO:0007744|PDB:3VI3, ECO:0007744|PDB:3VI4 |
| Chain | Residue | Details |
| B | GLU169 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | BINDING: in LIMBS binding site => ECO:0000269|PubMed:22451694, ECO:0000269|PubMed:33962943, ECO:0007744|PDB:3VI3, ECO:0007744|PDB:3VI4, ECO:0007744|PDB:7NXD |
| Chain | Residue | Details |
| B | ASN224 | |
| B | ASP226 | |
| B | PRO228 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| B | ASN30 | |
| B | ASN74 | |
| B | ASN77 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218 |
| Chain | Residue | Details |
| B | ASN192 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:22451694, ECO:0000269|PubMed:33962943, ECO:0007744|PDB:3VI3, ECO:0007744|PDB:3VI4, ECO:0007744|PDB:7NWL, ECO:0007744|PDB:7NXD |
| Chain | Residue | Details |
| B | ASN249 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:33962943, ECO:0007744|PDB:7NWL, ECO:0007744|PDB:7NXD |
| Chain | Residue | Details |
| B | ASN343 | |
| B | ASN397 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19349973, ECO:0000269|PubMed:22451694, ECO:0000269|PubMed:33962943, ECO:0007744|PDB:3VI3, ECO:0007744|PDB:3VI4, ECO:0007744|PDB:7NWL, ECO:0007744|PDB:7NXD |
| Chain | Residue | Details |
| B | ASN386 |
