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8W2R

HIV-1 P5-IN intasome core

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0003964molecular_functionRNA-directed DNA polymerase activity
A0004519molecular_functionendonuclease activity
A0006278biological_processRNA-templated DNA biosynthetic process
A0006310biological_processDNA recombination
A0015074biological_processDNA integration
A0035613molecular_functionRNA stem-loop binding
A0046718biological_processsymbiont entry into host cell
A0046872molecular_functionmetal ion binding
B0003677molecular_functionDNA binding
B0003964molecular_functionRNA-directed DNA polymerase activity
B0004519molecular_functionendonuclease activity
B0006278biological_processRNA-templated DNA biosynthetic process
B0006310biological_processDNA recombination
B0015074biological_processDNA integration
B0035613molecular_functionRNA stem-loop binding
B0046718biological_processsymbiont entry into host cell
B0046872molecular_functionmetal ion binding
C0003677molecular_functionDNA binding
C0003964molecular_functionRNA-directed DNA polymerase activity
C0004519molecular_functionendonuclease activity
C0006278biological_processRNA-templated DNA biosynthetic process
C0006310biological_processDNA recombination
C0015074biological_processDNA integration
C0035613molecular_functionRNA stem-loop binding
C0046718biological_processsymbiont entry into host cell
C0046872molecular_functionmetal ion binding
D0003677molecular_functionDNA binding
D0003964molecular_functionRNA-directed DNA polymerase activity
D0004519molecular_functionendonuclease activity
D0006278biological_processRNA-templated DNA biosynthetic process
D0006310biological_processDNA recombination
D0015074biological_processDNA integration
D0035613molecular_functionRNA stem-loop binding
D0046718biological_processsymbiont entry into host cell
D0046872molecular_functionmetal ion binding
I0003677molecular_functionDNA binding
I0003964molecular_functionRNA-directed DNA polymerase activity
I0004519molecular_functionendonuclease activity
I0006278biological_processRNA-templated DNA biosynthetic process
I0006310biological_processDNA recombination
I0015074biological_processDNA integration
I0035613molecular_functionRNA stem-loop binding
I0046718biological_processsymbiont entry into host cell
I0046872molecular_functionmetal ion binding
K0003677molecular_functionDNA binding
K0003964molecular_functionRNA-directed DNA polymerase activity
K0004519molecular_functionendonuclease activity
K0006278biological_processRNA-templated DNA biosynthetic process
K0006310biological_processDNA recombination
K0015074biological_processDNA integration
K0035613molecular_functionRNA stem-loop binding
K0046718biological_processsymbiont entry into host cell
K0046872molecular_functionmetal ion binding
L0003677molecular_functionDNA binding
L0003964molecular_functionRNA-directed DNA polymerase activity
L0004519molecular_functionendonuclease activity
L0006278biological_processRNA-templated DNA biosynthetic process
L0006310biological_processDNA recombination
L0015074biological_processDNA integration
L0035613molecular_functionRNA stem-loop binding
L0046718biological_processsymbiont entry into host cell
L0046872molecular_functionmetal ion binding
M0003677molecular_functionDNA binding
M0003964molecular_functionRNA-directed DNA polymerase activity
M0004519molecular_functionendonuclease activity
M0006278biological_processRNA-templated DNA biosynthetic process
M0006310biological_processDNA recombination
M0015074biological_processDNA integration
M0035613molecular_functionRNA stem-loop binding
M0046718biological_processsymbiont entry into host cell
M0046872molecular_functionmetal ion binding
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues328
DetailsZN_FING: Integrase-type => ECO:0000255|PROSITE-ProRule:PRU00450
ChainResidueDetails
AASP3-GLN44
BASP3-GLN44
CASP3-GLN44
DASP3-GLN44
IASP3-GLN44
KASP3-GLN44
LASP3-GLN44
MASP3-GLN44

site_idSWS_FT_FI2
Number of Residues376
DetailsDNA_BIND: Integrase-type => ECO:0000255|PROSITE-ProRule:PRU00506
ChainResidueDetails
APHE223-ASP270
BPHE223-ASP270
CPHE223-ASP270
DPHE223-ASP270
IPHE223-ASP270
KPHE223-ASP270
LPHE223-ASP270
MPHE223-ASP270

site_idSWS_FT_FI3
Number of Residues32
DetailsBINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00450
ChainResidueDetails
AHIS12
CHIS16
CCYS40
CCYS43
DHIS12
DHIS16
DCYS40
DCYS43
IHIS12
IHIS16
ICYS40
AHIS16
ICYS43
KHIS12
KHIS16
KCYS40
KCYS43
LHIS12
LHIS16
LCYS40
LCYS43
MHIS12
ACYS40
MHIS16
MCYS40
MCYS43
ACYS43
BHIS12
BHIS16
BCYS40
BCYS43
CHIS12

site_idSWS_FT_FI4
Number of Residues16
DetailsBINDING:
ChainResidueDetails
AASP64
IASP116
KASP64
KASP116
LASP64
LASP116
MASP64
MASP116
AASP116
BASP64
BASP116
CASP64
CASP116
DASP64
DASP116
IASP64

site_idSWS_FT_FI5
Number of Residues8
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:P04585
ChainResidueDetails
AGLU152
BGLU152
CGLU152
DGLU152
IGLU152
KGLU152
LGLU152
MGLU152

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PDB entries from 2024-07-24

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