8W2R
HIV-1 P5-IN intasome core
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0015074 | biological_process | DNA integration |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0015074 | biological_process | DNA integration |
| C | 0003676 | molecular_function | nucleic acid binding |
| C | 0008270 | molecular_function | zinc ion binding |
| C | 0015074 | biological_process | DNA integration |
| D | 0003676 | molecular_function | nucleic acid binding |
| D | 0008270 | molecular_function | zinc ion binding |
| D | 0015074 | biological_process | DNA integration |
| I | 0003676 | molecular_function | nucleic acid binding |
| I | 0008270 | molecular_function | zinc ion binding |
| I | 0015074 | biological_process | DNA integration |
| K | 0003676 | molecular_function | nucleic acid binding |
| K | 0008270 | molecular_function | zinc ion binding |
| K | 0015074 | biological_process | DNA integration |
| L | 0003676 | molecular_function | nucleic acid binding |
| L | 0008270 | molecular_function | zinc ion binding |
| L | 0015074 | biological_process | DNA integration |
| M | 0003676 | molecular_function | nucleic acid binding |
| M | 0008270 | molecular_function | zinc ion binding |
| M | 0015074 | biological_process | DNA integration |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 328 |
| Details | ZN_FING: Integrase-type => ECO:0000255|PROSITE-ProRule:PRU00450 |
| Chain | Residue | Details |
| A | ASP3-GLN44 | |
| B | ASP3-GLN44 | |
| C | ASP3-GLN44 | |
| D | ASP3-GLN44 | |
| I | ASP3-GLN44 | |
| K | ASP3-GLN44 | |
| L | ASP3-GLN44 | |
| M | ASP3-GLN44 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 376 |
| Details | DNA_BIND: Integrase-type => ECO:0000255|PROSITE-ProRule:PRU00506 |
| Chain | Residue | Details |
| A | PHE223-ASP270 | |
| B | PHE223-ASP270 | |
| C | PHE223-ASP270 | |
| D | PHE223-ASP270 | |
| I | PHE223-ASP270 | |
| K | PHE223-ASP270 | |
| L | PHE223-ASP270 | |
| M | PHE223-ASP270 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 32 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00450 |
| Chain | Residue | Details |
| A | HIS12 | |
| C | HIS16 | |
| C | CYS40 | |
| C | CYS43 | |
| D | HIS12 | |
| D | HIS16 | |
| D | CYS40 | |
| D | CYS43 | |
| I | HIS12 | |
| I | HIS16 | |
| I | CYS40 | |
| A | HIS16 | |
| I | CYS43 | |
| K | HIS12 | |
| K | HIS16 | |
| K | CYS40 | |
| K | CYS43 | |
| L | HIS12 | |
| L | HIS16 | |
| L | CYS40 | |
| L | CYS43 | |
| M | HIS12 | |
| A | CYS40 | |
| M | HIS16 | |
| M | CYS40 | |
| M | CYS43 | |
| A | CYS43 | |
| B | HIS12 | |
| B | HIS16 | |
| B | CYS40 | |
| B | CYS43 | |
| C | HIS12 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 16 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | ASP64 | |
| I | ASP116 | |
| K | ASP64 | |
| K | ASP116 | |
| L | ASP64 | |
| L | ASP116 | |
| M | ASP64 | |
| M | ASP116 | |
| A | ASP116 | |
| B | ASP64 | |
| B | ASP116 | |
| C | ASP64 | |
| C | ASP116 | |
| D | ASP64 | |
| D | ASP116 | |
| I | ASP64 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:P04585 |
| Chain | Residue | Details |
| A | GLU152 | |
| B | GLU152 | |
| C | GLU152 | |
| D | GLU152 | |
| I | GLU152 | |
| K | GLU152 | |
| L | GLU152 | |
| M | GLU152 |
