8W2E

SARS-CoV-2 M protein dimer in complex with JNJ-9676 and Fab-B

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005886	cellular_component	plasma membrane
A	0016020	cellular_component	membrane
A	0019031	cellular_component	viral envelope
A	0030430	cellular_component	host cell cytoplasm
A	0033644	cellular_component	host cell membrane
A	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
A	0039660	molecular_function	structural constituent of virion
A	0042802	molecular_function	identical protein binding
A	0044178	cellular_component	host cell Golgi membrane
A	0044423	cellular_component	virion component
A	0055036	cellular_component	virion membrane
A	0140311	molecular_function	protein sequestering activity
B	0005515	molecular_function	protein binding
B	0005886	cellular_component	plasma membrane
B	0016020	cellular_component	membrane
B	0019031	cellular_component	viral envelope
B	0030430	cellular_component	host cell cytoplasm
B	0033644	cellular_component	host cell membrane
B	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
B	0039660	molecular_function	structural constituent of virion
B	0042802	molecular_function	identical protein binding
B	0044178	cellular_component	host cell Golgi membrane
B	0044423	cellular_component	virion component
B	0055036	cellular_component	virion membrane
B	0140311	molecular_function	protein sequestering activity

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH

Chain	Residue	Details
C	TYR196-HIS202

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	14
Details	Topological domain: {"description":"Intravirion","evidences":[{"source":"PubMed","id":"36264056","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	108
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"36264056","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	8
Details	Topological domain: {"description":"Virion surface","evidences":[{"source":"PubMed","id":"36264056","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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