8W1H
Crystal Structure of human Tryptophan 2,3-dioxygenase in complex with PYN3 inhibitor
This is a non-PDB format compatible entry.
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_03020, ECO:0000269|PubMed:27762317, ECO:0007744|PDB:5TI9 |
| Chain | Residue | Details |
| A | PHE72 | |
| D | PHE72 | |
| D | ARG144 | |
| D | THR342 | |
| A | ARG144 | |
| A | THR342 | |
| B | PHE72 | |
| B | ARG144 | |
| B | THR342 | |
| C | PHE72 | |
| C | ARG144 | |
| C | THR342 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: axial binding residue => ECO:0000255|HAMAP-Rule:MF_03020, ECO:0000269|PubMed:27762317, ECO:0007744|PDB:5TI9 |
| Chain | Residue | Details |
| A | HIS328 | |
| B | HIS328 | |
| C | HIS328 | |
| D | HIS328 |
