8W0M

Crystal structure of Acetyl-CoA synthetase 2 from Candida albicans in complex with a Acetyl Sulfamate AMP ester inhibitor

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003987	molecular_function	acetate-CoA ligase activity
A	0005524	molecular_function	ATP binding
A	0005829	cellular_component	cytosol
A	0006085	biological_process	acetyl-CoA biosynthetic process
A	0016208	molecular_function	AMP binding
A	0016874	molecular_function	ligase activity
A	0019427	biological_process	acetyl-CoA biosynthetic process from acetate
B	0000166	molecular_function	nucleotide binding
B	0003987	molecular_function	acetate-CoA ligase activity
B	0005524	molecular_function	ATP binding
B	0005829	cellular_component	cytosol
B	0006085	biological_process	acetyl-CoA biosynthetic process
B	0016208	molecular_function	AMP binding
B	0016874	molecular_function	ligase activity
B	0019427	biological_process	acetyl-CoA biosynthetic process from acetate
C	0000166	molecular_function	nucleotide binding
C	0003987	molecular_function	acetate-CoA ligase activity
C	0005524	molecular_function	ATP binding
C	0005829	cellular_component	cytosol
C	0006085	biological_process	acetyl-CoA biosynthetic process
C	0016208	molecular_function	AMP binding
C	0016874	molecular_function	ligase activity
C	0019427	biological_process	acetyl-CoA biosynthetic process from acetate

Functional Information from PROSITE/UniProt

site_id	PS00455
Number of Residues	12
Details	AMP_BINDING Putative AMP-binding domain signature. LLYTSGSTGtPK

Chain	Residue	Details
A	LEU291-LYS302

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	42
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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