8VSD

avb8/L-TGF-b1/GARP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0007155	biological_process	cell adhesion
A	0008305	cellular_component	integrin complex
E	0000122	biological_process	negative regulation of transcription by RNA polymerase II
E	0000902	biological_process	cell morphogenesis
E	0001570	biological_process	vasculogenesis
E	0001657	biological_process	ureteric bud development
E	0001666	biological_process	response to hypoxia
E	0001763	biological_process	morphogenesis of a branching structure
E	0001775	biological_process	cell activation
E	0001837	biological_process	epithelial to mesenchymal transition
E	0001843	biological_process	neural tube closure
E	0002028	biological_process	regulation of sodium ion transport
E	0002040	biological_process	sprouting angiogenesis
E	0002062	biological_process	chondrocyte differentiation
E	0002069	biological_process	columnar/cuboidal epithelial cell maturation
E	0002244	biological_process	hematopoietic progenitor cell differentiation
E	0002248	biological_process	connective tissue replacement involved in inflammatory response wound healing
E	0002460	biological_process	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
E	0002513	biological_process	tolerance induction to self antigen
E	0002859	biological_process	negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
E	0003179	biological_process	heart valve morphogenesis
E	0003180	biological_process	aortic valve morphogenesis
E	0005114	molecular_function	type II transforming growth factor beta receptor binding
E	0005125	molecular_function	cytokine activity
E	0005160	molecular_function	transforming growth factor beta receptor binding
E	0005515	molecular_function	protein binding
E	0005576	cellular_component	extracellular region
E	0005615	cellular_component	extracellular space
E	0005634	cellular_component	nucleus
E	0005737	cellular_component	cytoplasm
E	0005796	cellular_component	Golgi lumen
E	0005886	cellular_component	plasma membrane
E	0005902	cellular_component	microvillus
E	0006611	biological_process	protein export from nucleus
E	0006754	biological_process	ATP biosynthetic process
E	0006796	biological_process	phosphate-containing compound metabolic process
E	0006874	biological_process	intracellular calcium ion homeostasis
E	0006954	biological_process	inflammatory response
E	0007179	biological_process	transforming growth factor beta receptor signaling pathway
E	0007219	biological_process	Notch signaling pathway
E	0007406	biological_process	negative regulation of neuroblast proliferation
E	0007435	biological_process	salivary gland morphogenesis
E	0007492	biological_process	endoderm development
E	0007507	biological_process	heart development
E	0007565	biological_process	female pregnancy
E	0008083	molecular_function	growth factor activity
E	0008283	biological_process	cell population proliferation
E	0008284	biological_process	positive regulation of cell population proliferation
E	0008285	biological_process	negative regulation of cell population proliferation
E	0008354	biological_process	germ cell migration
E	0009410	biological_process	response to xenobiotic stimulus
E	0009611	biological_process	response to wounding
E	0009749	biological_process	response to glucose
E	0009986	cellular_component	cell surface
E	0010332	biological_process	response to gamma radiation
E	0010467	biological_process	gene expression
E	0010468	biological_process	regulation of gene expression
E	0010575	biological_process	positive regulation of vascular endothelial growth factor production
E	0010628	biological_process	positive regulation of gene expression
E	0010629	biological_process	negative regulation of gene expression
E	0010716	biological_process	negative regulation of extracellular matrix disassembly
E	0010718	biological_process	positive regulation of epithelial to mesenchymal transition
E	0010742	biological_process	macrophage derived foam cell differentiation
E	0010763	biological_process	positive regulation of fibroblast migration
E	0010936	biological_process	negative regulation of macrophage cytokine production
E	0014003	biological_process	oligodendrocyte development
E	0014008	biological_process	positive regulation of microglia differentiation
E	0016202	biological_process	regulation of striated muscle tissue development
E	0019899	molecular_function	enzyme binding
E	0021915	biological_process	neural tube development
E	0030141	cellular_component	secretory granule
E	0030214	biological_process	hyaluronan catabolic process
E	0030217	biological_process	T cell differentiation
E	0030279	biological_process	negative regulation of ossification
E	0030308	biological_process	negative regulation of cell growth
E	0030316	biological_process	osteoclast differentiation
E	0030334	biological_process	regulation of cell migration
E	0030335	biological_process	positive regulation of cell migration
E	0030424	cellular_component	axon
E	0030879	biological_process	mammary gland development
E	0031012	cellular_component	extracellular matrix
E	0031093	cellular_component	platelet alpha granule lumen
E	0031100	biological_process	animal organ regeneration
E	0031293	biological_process	membrane protein intracellular domain proteolysis
E	0031334	biological_process	positive regulation of protein-containing complex assembly
E	0031536	biological_process	positive regulation of exit from mitosis
E	0032355	biological_process	response to estradiol
E	0032570	biological_process	response to progesterone
E	0032667	biological_process	regulation of interleukin-23 production
E	0032700	biological_process	negative regulation of interleukin-17 production
E	0032740	biological_process	positive regulation of interleukin-17 production
E	0032755	biological_process	positive regulation of interleukin-6 production
E	0032760	biological_process	positive regulation of tumor necrosis factor production
E	0032801	biological_process	receptor catabolic process
E	0032930	biological_process	positive regulation of superoxide anion generation
E	0032943	biological_process	mononuclear cell proliferation
E	0032956	biological_process	regulation of actin cytoskeleton organization
E	0032967	biological_process	positive regulation of collagen biosynthetic process
E	0033280	biological_process	response to vitamin D
E	0034616	biological_process	response to laminar fluid shear stress
E	0034713	molecular_function	type I transforming growth factor beta receptor binding
E	0034714	molecular_function	type III transforming growth factor beta receptor binding
E	0035902	biological_process	response to immobilization stress
E	0036120	biological_process	cellular response to platelet-derived growth factor stimulus
E	0036446	biological_process	myofibroblast differentiation
E	0042098	biological_process	T cell proliferation
E	0042110	biological_process	T cell activation
E	0042127	biological_process	regulation of cell population proliferation
E	0042130	biological_process	negative regulation of T cell proliferation
E	0042306	biological_process	regulation of protein import into nucleus
E	0042307	biological_process	positive regulation of protein import into nucleus
E	0042475	biological_process	odontogenesis of dentin-containing tooth
E	0042482	biological_process	positive regulation of odontogenesis
E	0042552	biological_process	myelination
E	0042802	molecular_function	identical protein binding
E	0043025	cellular_component	neuronal cell body
E	0043029	biological_process	T cell homeostasis
E	0043065	biological_process	positive regulation of apoptotic process
E	0043117	biological_process	positive regulation of vascular permeability
E	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
E	0043129	biological_process	surfactant homeostasis
E	0043410	biological_process	positive regulation of MAPK cascade
E	0043536	biological_process	positive regulation of blood vessel endothelial cell migration
E	0043537	biological_process	negative regulation of blood vessel endothelial cell migration
E	0043539	molecular_function	protein serine/threonine kinase activator activity
E	0044877	molecular_function	protein-containing complex binding
E	0045066	biological_process	regulatory T cell differentiation
E	0045216	biological_process	cell-cell junction organization
E	0045471	biological_process	response to ethanol
E	0045589	biological_process	regulation of regulatory T cell differentiation
E	0045591	biological_process	positive regulation of regulatory T cell differentiation
E	0045596	biological_process	negative regulation of cell differentiation
E	0045597	biological_process	positive regulation of cell differentiation
E	0045599	biological_process	negative regulation of fat cell differentiation
E	0045662	biological_process	negative regulation of myoblast differentiation
E	0045742	biological_process	positive regulation of epidermal growth factor receptor signaling pathway
E	0045786	biological_process	negative regulation of cell cycle
E	0045892	biological_process	negative regulation of DNA-templated transcription
E	0045893	biological_process	positive regulation of DNA-templated transcription
E	0045944	biological_process	positive regulation of transcription by RNA polymerase II
E	0046716	biological_process	muscle cell cellular homeostasis
E	0048146	biological_process	positive regulation of fibroblast proliferation
E	0048286	biological_process	lung alveolus development
E	0048298	biological_process	positive regulation of isotype switching to IgA isotypes
E	0048535	biological_process	lymph node development
E	0048565	biological_process	digestive tract development
E	0048642	biological_process	negative regulation of skeletal muscle tissue development
E	0048661	biological_process	positive regulation of smooth muscle cell proliferation
E	0048839	biological_process	inner ear development
E	0050673	biological_process	epithelial cell proliferation
E	0050679	biological_process	positive regulation of epithelial cell proliferation
E	0050680	biological_process	negative regulation of epithelial cell proliferation
E	0050714	biological_process	positive regulation of protein secretion
E	0050729	biological_process	positive regulation of inflammatory response
E	0050765	biological_process	negative regulation of phagocytosis
E	0050832	biological_process	defense response to fungus
E	0050868	biological_process	negative regulation of T cell activation
E	0050921	biological_process	positive regulation of chemotaxis
E	0051130	biological_process	positive regulation of cellular component organization
E	0051152	biological_process	positive regulation of smooth muscle cell differentiation
E	0051240	biological_process	positive regulation of multicellular organismal process
E	0051247	biological_process	positive regulation of protein metabolic process
E	0051280	biological_process	negative regulation of release of sequestered calcium ion into cytosol
E	0051402	biological_process	neuron apoptotic process
E	0051726	biological_process	regulation of cell cycle
E	0051781	biological_process	positive regulation of cell division
E	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
E	0055010	biological_process	ventricular cardiac muscle tissue morphogenesis
E	0055091	biological_process	phospholipid homeostasis
E	0060070	biological_process	canonical Wnt signaling pathway
E	0060312	biological_process	regulation of blood vessel remodeling
E	0060325	biological_process	face morphogenesis
E	0060364	biological_process	frontal suture morphogenesis
E	0060391	biological_process	positive regulation of SMAD protein signal transduction
E	0060435	biological_process	bronchiole development
E	0060744	biological_process	mammary gland branching involved in thelarche
E	0060751	biological_process	branch elongation involved in mammary gland duct branching
E	0060762	biological_process	regulation of branching involved in mammary gland duct morphogenesis
E	0061035	biological_process	regulation of cartilage development
E	0061298	biological_process	retina vasculature development in camera-type eye
E	0061448	biological_process	connective tissue development
E	0061520	biological_process	Langerhans cell differentiation
E	0070168	biological_process	negative regulation of biomineral tissue development
E	0070173	biological_process	regulation of enamel mineralization
E	0070306	biological_process	lens fiber cell differentiation
E	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
E	0070723	biological_process	response to cholesterol
E	0071260	biological_process	cellular response to mechanical stimulus
E	0071333	biological_process	cellular response to glucose stimulus
E	0071363	biological_process	cellular response to growth factor stimulus
E	0071404	biological_process	cellular response to low-density lipoprotein particle stimulus
E	0071456	biological_process	cellular response to hypoxia
E	0071479	biological_process	cellular response to ionizing radiation
E	0071549	biological_process	cellular response to dexamethasone stimulus
E	0071560	biological_process	cellular response to transforming growth factor beta stimulus
E	0071677	biological_process	positive regulation of mononuclear cell migration
E	0071895	biological_process	odontoblast differentiation
E	0072089	biological_process	stem cell proliferation
E	0072562	cellular_component	blood microparticle
E	0085029	biological_process	extracellular matrix assembly
E	0090190	biological_process	positive regulation of branching involved in ureteric bud morphogenesis
E	0090263	biological_process	positive regulation of canonical Wnt signaling pathway
E	0097191	biological_process	extrinsic apoptotic signaling pathway
E	0097421	biological_process	liver regeneration
E	0098586	biological_process	cellular response to virus
E	0141091	biological_process	transforming growth factor beta receptor superfamily signaling pathway
E	1900126	biological_process	negative regulation of hyaluronan biosynthetic process
E	1900182	biological_process	positive regulation of protein localization to nucleus
E	1901203	biological_process	positive regulation of extracellular matrix assembly
E	1902074	biological_process	response to salt
E	1902462	biological_process	positive regulation of mesenchymal stem cell proliferation
E	1902893	biological_process	regulation of miRNA transcription
E	1902894	biological_process	negative regulation of miRNA transcription
E	1902895	biological_process	positive regulation of miRNA transcription
E	1903077	biological_process	negative regulation of protein localization to plasma membrane
E	1904018	biological_process	positive regulation of vasculature development
E	1904894	biological_process	positive regulation of receptor signaling pathway via STAT
E	1905005	biological_process	regulation of epithelial to mesenchymal transition involved in endocardial cushion formation
E	1905641	biological_process	cellular response to acetaldehyde
E	1990314	biological_process	cellular response to insulin-like growth factor stimulus
E	1990402	biological_process	embryonic liver development
E	2000048	biological_process	negative regulation of cell-cell adhesion mediated by cadherin
E	2000343	biological_process	positive regulation of chemokine (C-X-C motif) ligand 2 production
E	2000353	biological_process	positive regulation of endothelial cell apoptotic process
E	2000636	biological_process	positive regulation of primary miRNA processing
E	2000648	biological_process	positive regulation of stem cell proliferation
E	2000727	biological_process	positive regulation of cardiac muscle cell differentiation
F	0000122	biological_process	negative regulation of transcription by RNA polymerase II
F	0000902	biological_process	cell morphogenesis
F	0001570	biological_process	vasculogenesis
F	0001657	biological_process	ureteric bud development
F	0001666	biological_process	response to hypoxia
F	0001763	biological_process	morphogenesis of a branching structure
F	0001775	biological_process	cell activation
F	0001837	biological_process	epithelial to mesenchymal transition
F	0001843	biological_process	neural tube closure
F	0002028	biological_process	regulation of sodium ion transport
F	0002040	biological_process	sprouting angiogenesis
F	0002062	biological_process	chondrocyte differentiation
F	0002069	biological_process	columnar/cuboidal epithelial cell maturation
F	0002244	biological_process	hematopoietic progenitor cell differentiation
F	0002248	biological_process	connective tissue replacement involved in inflammatory response wound healing
F	0002460	biological_process	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
F	0002513	biological_process	tolerance induction to self antigen
F	0002859	biological_process	negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
F	0003179	biological_process	heart valve morphogenesis
F	0003180	biological_process	aortic valve morphogenesis
F	0005114	molecular_function	type II transforming growth factor beta receptor binding
F	0005125	molecular_function	cytokine activity
F	0005160	molecular_function	transforming growth factor beta receptor binding
F	0005515	molecular_function	protein binding
F	0005576	cellular_component	extracellular region
F	0005615	cellular_component	extracellular space
F	0005634	cellular_component	nucleus
F	0005737	cellular_component	cytoplasm
F	0005796	cellular_component	Golgi lumen
F	0005886	cellular_component	plasma membrane
F	0005902	cellular_component	microvillus
F	0006611	biological_process	protein export from nucleus
F	0006754	biological_process	ATP biosynthetic process
F	0006796	biological_process	phosphate-containing compound metabolic process
F	0006874	biological_process	intracellular calcium ion homeostasis
F	0006954	biological_process	inflammatory response
F	0007179	biological_process	transforming growth factor beta receptor signaling pathway
F	0007219	biological_process	Notch signaling pathway
F	0007406	biological_process	negative regulation of neuroblast proliferation
F	0007435	biological_process	salivary gland morphogenesis
F	0007492	biological_process	endoderm development
F	0007507	biological_process	heart development
F	0007565	biological_process	female pregnancy
F	0008083	molecular_function	growth factor activity
F	0008283	biological_process	cell population proliferation
F	0008284	biological_process	positive regulation of cell population proliferation
F	0008285	biological_process	negative regulation of cell population proliferation
F	0008354	biological_process	germ cell migration
F	0009410	biological_process	response to xenobiotic stimulus
F	0009611	biological_process	response to wounding
F	0009749	biological_process	response to glucose
F	0009986	cellular_component	cell surface
F	0010332	biological_process	response to gamma radiation
F	0010467	biological_process	gene expression
F	0010468	biological_process	regulation of gene expression
F	0010575	biological_process	positive regulation of vascular endothelial growth factor production
F	0010628	biological_process	positive regulation of gene expression
F	0010629	biological_process	negative regulation of gene expression
F	0010716	biological_process	negative regulation of extracellular matrix disassembly
F	0010718	biological_process	positive regulation of epithelial to mesenchymal transition
F	0010742	biological_process	macrophage derived foam cell differentiation
F	0010763	biological_process	positive regulation of fibroblast migration
F	0010936	biological_process	negative regulation of macrophage cytokine production
F	0014003	biological_process	oligodendrocyte development
F	0014008	biological_process	positive regulation of microglia differentiation
F	0016202	biological_process	regulation of striated muscle tissue development
F	0019899	molecular_function	enzyme binding
F	0021915	biological_process	neural tube development
F	0030141	cellular_component	secretory granule
F	0030214	biological_process	hyaluronan catabolic process
F	0030217	biological_process	T cell differentiation
F	0030279	biological_process	negative regulation of ossification
F	0030308	biological_process	negative regulation of cell growth
F	0030316	biological_process	osteoclast differentiation
F	0030334	biological_process	regulation of cell migration
F	0030335	biological_process	positive regulation of cell migration
F	0030424	cellular_component	axon
F	0030879	biological_process	mammary gland development
F	0031012	cellular_component	extracellular matrix
F	0031093	cellular_component	platelet alpha granule lumen
F	0031100	biological_process	animal organ regeneration
F	0031293	biological_process	membrane protein intracellular domain proteolysis
F	0031334	biological_process	positive regulation of protein-containing complex assembly
F	0031536	biological_process	positive regulation of exit from mitosis
F	0032355	biological_process	response to estradiol
F	0032570	biological_process	response to progesterone
F	0032667	biological_process	regulation of interleukin-23 production
F	0032700	biological_process	negative regulation of interleukin-17 production
F	0032740	biological_process	positive regulation of interleukin-17 production
F	0032755	biological_process	positive regulation of interleukin-6 production
F	0032760	biological_process	positive regulation of tumor necrosis factor production
F	0032801	biological_process	receptor catabolic process
F	0032930	biological_process	positive regulation of superoxide anion generation
F	0032943	biological_process	mononuclear cell proliferation
F	0032956	biological_process	regulation of actin cytoskeleton organization
F	0032967	biological_process	positive regulation of collagen biosynthetic process
F	0033280	biological_process	response to vitamin D
F	0034616	biological_process	response to laminar fluid shear stress
F	0034713	molecular_function	type I transforming growth factor beta receptor binding
F	0034714	molecular_function	type III transforming growth factor beta receptor binding
F	0035902	biological_process	response to immobilization stress
F	0036120	biological_process	cellular response to platelet-derived growth factor stimulus
F	0036446	biological_process	myofibroblast differentiation
F	0042098	biological_process	T cell proliferation
F	0042110	biological_process	T cell activation
F	0042127	biological_process	regulation of cell population proliferation
F	0042130	biological_process	negative regulation of T cell proliferation
F	0042306	biological_process	regulation of protein import into nucleus
F	0042307	biological_process	positive regulation of protein import into nucleus
F	0042475	biological_process	odontogenesis of dentin-containing tooth
F	0042482	biological_process	positive regulation of odontogenesis
F	0042552	biological_process	myelination
F	0042802	molecular_function	identical protein binding
F	0043025	cellular_component	neuronal cell body
F	0043029	biological_process	T cell homeostasis
F	0043065	biological_process	positive regulation of apoptotic process
F	0043117	biological_process	positive regulation of vascular permeability
F	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
F	0043129	biological_process	surfactant homeostasis
F	0043410	biological_process	positive regulation of MAPK cascade
F	0043536	biological_process	positive regulation of blood vessel endothelial cell migration
F	0043537	biological_process	negative regulation of blood vessel endothelial cell migration
F	0043539	molecular_function	protein serine/threonine kinase activator activity
F	0044877	molecular_function	protein-containing complex binding
F	0045066	biological_process	regulatory T cell differentiation
F	0045216	biological_process	cell-cell junction organization
F	0045471	biological_process	response to ethanol
F	0045589	biological_process	regulation of regulatory T cell differentiation
F	0045591	biological_process	positive regulation of regulatory T cell differentiation
F	0045596	biological_process	negative regulation of cell differentiation
F	0045597	biological_process	positive regulation of cell differentiation
F	0045599	biological_process	negative regulation of fat cell differentiation
F	0045662	biological_process	negative regulation of myoblast differentiation
F	0045742	biological_process	positive regulation of epidermal growth factor receptor signaling pathway
F	0045786	biological_process	negative regulation of cell cycle
F	0045892	biological_process	negative regulation of DNA-templated transcription
F	0045893	biological_process	positive regulation of DNA-templated transcription
F	0045944	biological_process	positive regulation of transcription by RNA polymerase II
F	0046716	biological_process	muscle cell cellular homeostasis
F	0048146	biological_process	positive regulation of fibroblast proliferation
F	0048286	biological_process	lung alveolus development
F	0048298	biological_process	positive regulation of isotype switching to IgA isotypes
F	0048535	biological_process	lymph node development
F	0048565	biological_process	digestive tract development
F	0048642	biological_process	negative regulation of skeletal muscle tissue development
F	0048661	biological_process	positive regulation of smooth muscle cell proliferation
F	0048839	biological_process	inner ear development
F	0050673	biological_process	epithelial cell proliferation
F	0050679	biological_process	positive regulation of epithelial cell proliferation
F	0050680	biological_process	negative regulation of epithelial cell proliferation
F	0050714	biological_process	positive regulation of protein secretion
F	0050729	biological_process	positive regulation of inflammatory response
F	0050765	biological_process	negative regulation of phagocytosis
F	0050832	biological_process	defense response to fungus
F	0050868	biological_process	negative regulation of T cell activation
F	0050921	biological_process	positive regulation of chemotaxis
F	0051130	biological_process	positive regulation of cellular component organization
F	0051152	biological_process	positive regulation of smooth muscle cell differentiation
F	0051240	biological_process	positive regulation of multicellular organismal process
F	0051247	biological_process	positive regulation of protein metabolic process
F	0051280	biological_process	negative regulation of release of sequestered calcium ion into cytosol
F	0051402	biological_process	neuron apoptotic process
F	0051726	biological_process	regulation of cell cycle
F	0051781	biological_process	positive regulation of cell division
F	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
F	0055010	biological_process	ventricular cardiac muscle tissue morphogenesis
F	0055091	biological_process	phospholipid homeostasis
F	0060070	biological_process	canonical Wnt signaling pathway
F	0060312	biological_process	regulation of blood vessel remodeling
F	0060325	biological_process	face morphogenesis
F	0060364	biological_process	frontal suture morphogenesis
F	0060391	biological_process	positive regulation of SMAD protein signal transduction
F	0060435	biological_process	bronchiole development
F	0060744	biological_process	mammary gland branching involved in thelarche
F	0060751	biological_process	branch elongation involved in mammary gland duct branching
F	0060762	biological_process	regulation of branching involved in mammary gland duct morphogenesis
F	0061035	biological_process	regulation of cartilage development
F	0061298	biological_process	retina vasculature development in camera-type eye
F	0061448	biological_process	connective tissue development
F	0061520	biological_process	Langerhans cell differentiation
F	0070168	biological_process	negative regulation of biomineral tissue development
F	0070173	biological_process	regulation of enamel mineralization
F	0070306	biological_process	lens fiber cell differentiation
F	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
F	0070723	biological_process	response to cholesterol
F	0071260	biological_process	cellular response to mechanical stimulus
F	0071333	biological_process	cellular response to glucose stimulus
F	0071363	biological_process	cellular response to growth factor stimulus
F	0071404	biological_process	cellular response to low-density lipoprotein particle stimulus
F	0071456	biological_process	cellular response to hypoxia
F	0071479	biological_process	cellular response to ionizing radiation
F	0071549	biological_process	cellular response to dexamethasone stimulus
F	0071560	biological_process	cellular response to transforming growth factor beta stimulus
F	0071677	biological_process	positive regulation of mononuclear cell migration
F	0071895	biological_process	odontoblast differentiation
F	0072089	biological_process	stem cell proliferation
F	0072562	cellular_component	blood microparticle
F	0085029	biological_process	extracellular matrix assembly
F	0090190	biological_process	positive regulation of branching involved in ureteric bud morphogenesis
F	0090263	biological_process	positive regulation of canonical Wnt signaling pathway
F	0097191	biological_process	extrinsic apoptotic signaling pathway
F	0097421	biological_process	liver regeneration
F	0098586	biological_process	cellular response to virus
F	0141091	biological_process	transforming growth factor beta receptor superfamily signaling pathway
F	1900126	biological_process	negative regulation of hyaluronan biosynthetic process
F	1900182	biological_process	positive regulation of protein localization to nucleus
F	1901203	biological_process	positive regulation of extracellular matrix assembly
F	1902074	biological_process	response to salt
F	1902462	biological_process	positive regulation of mesenchymal stem cell proliferation
F	1902893	biological_process	regulation of miRNA transcription
F	1902894	biological_process	negative regulation of miRNA transcription
F	1902895	biological_process	positive regulation of miRNA transcription
F	1903077	biological_process	negative regulation of protein localization to plasma membrane
F	1904018	biological_process	positive regulation of vasculature development
F	1904894	biological_process	positive regulation of receptor signaling pathway via STAT
F	1905005	biological_process	regulation of epithelial to mesenchymal transition involved in endocardial cushion formation
F	1905641	biological_process	cellular response to acetaldehyde
F	1990314	biological_process	cellular response to insulin-like growth factor stimulus
F	1990402	biological_process	embryonic liver development
F	2000048	biological_process	negative regulation of cell-cell adhesion mediated by cadherin
F	2000343	biological_process	positive regulation of chemokine (C-X-C motif) ligand 2 production
F	2000353	biological_process	positive regulation of endothelial cell apoptotic process
F	2000636	biological_process	positive regulation of primary miRNA processing
F	2000648	biological_process	positive regulation of stem cell proliferation
F	2000727	biological_process	positive regulation of cardiac muscle cell differentiation

Functional Information from PROSITE/UniProt

site_id	PS00250
Number of Residues	16
Details	TGF_BETA_1 TGF-beta family signature. IhePkgYhanfClGpC

Chain	Residue	Details
E	ILE282-CYS297

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	23
Details	Repeat: {"description":"LRR 1","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	21
Details	Repeat: {"description":"LRR 2","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	20
Details	Repeat: {"description":"LRR 4","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	21
Details	Repeat: {"description":"LRR 5","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	21
Details	Repeat: {"description":"LRR 6","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	21
Details	Repeat: {"description":"LRR 7","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	20
Details	Repeat: {"description":"LRR 8","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	21
Details	Repeat: {"description":"LRR 9","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	23
Details	Repeat: {"description":"LRR 11","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	23
Details	Repeat: {"description":"LRR 12","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	21
Details	Repeat: {"description":"LRR 13","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	21
Details	Repeat: {"description":"LRR 14","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	21
Details	Repeat: {"description":"LRR 15","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	21
Details	Repeat: {"description":"LRR 16","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	21
Details	Repeat: {"description":"LRR 17","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	21
Details	Repeat: {"description":"LRR 18","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	21
Details	Repeat: {"description":"LRR 19","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	21
Details	Repeat: {"description":"LRR 20","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	11
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	66
Details	Repeat: {"description":"FG-GAP 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00803","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	61
Details	Repeat: {"description":"FG-GAP 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00803","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	52
Details	Repeat: {"description":"FG-GAP 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00803","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	54
Details	Repeat: {"description":"FG-GAP 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00803","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	65
Details	Repeat: {"description":"FG-GAP 5","evidences":[{"source":"PROSITE-ProRule","id":"PRU00803","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	57
Details	Repeat: {"description":"FG-GAP 6","evidences":[{"source":"PROSITE-ProRule","id":"PRU00803","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	63
Details	Repeat: {"description":"FG-GAP 7","evidences":[{"source":"PROSITE-ProRule","id":"PRU00803","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	20
Details	Binding site: {"evidences":[{"source":"PubMed","id":"19704023","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28117447","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3IJE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FFG","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI28
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19349973","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19704023","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28117447","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3IJE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19704023","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28117447","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3IJE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI30
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"12754519","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19704023","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28117447","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3IJE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI31
Number of Residues	238
Details	Domain: {"description":"VWFA","evidences":[{"source":"PubMed","id":"31792290","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI32
Number of Residues	2
Details	Binding site: {"description":"in MIDAS binding site","evidences":[{"source":"PubMed","id":"31792290","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6OM1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OM2","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI33
Number of Residues	1
Details	Binding site: {"description":"in MIDAS binding site","evidences":[{"source":"PubMed","id":"31792290","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6OM2","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI34
Number of Residues	4
Details	Binding site: {"description":"in LIMBS binding site","evidences":[{"source":"PubMed","id":"31792290","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6OM1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OM2","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI35
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"31792290","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6OM1","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI36
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"31792290","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6OM1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OM2","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI37
Number of Residues	26
Details	Region: {"description":"Bowtie tail","evidences":[{"source":"PubMed","id":"28117447","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI38
Number of Residues	2
Details	Motif: {"description":"Cell attachment site","evidences":[{"source":"PubMed","id":"28117447","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI39
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"16263699","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16335952","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28117447","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5FFO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI40
Number of Residues	44
Details	Region: {"description":"Straightjacket domain","evidences":[{"source":"UniProtKB","id":"P07200","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---