8VF9
Binary DNA Polymerase Beta bound to DNA containing primer terminal dA base-paired with FapydG
Functional Information from PROSITE/UniProt
| site_id | PS00522 |
| Number of Residues | 20 |
| Details | DNA_POLYMERASE_X DNA polymerase family X signature. GSFrRGaesSgDMDVLLthP |
| Chain | Residue | Details |
| A | GLY179-PRO198 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Nucleophile; Schiff-base intermediate with DNA; for 5'-dRP lyase activity => ECO:0000269|PubMed:9572863 |
| Chain | Residue | Details |
| A | LYS72 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:12517346, ECO:0000269|PubMed:8841120, ECO:0000269|PubMed:9287163, ECO:0007744|PDB:1BPX, ECO:0007744|PDB:1BPZ, ECO:0007744|PDB:1MQ3, ECO:0007744|PDB:1ZQO, ECO:0007744|PDB:1ZQQ |
| Chain | Residue | Details |
| A | LYS60 | |
| A | LEU62 | |
| A | VAL65 | |
| A | THR101 | |
| A | VAL103 | |
| A | ILE106 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:8841119, ECO:0007744|PDB:8ICW, ECO:0007744|PDB:8ICX, ECO:0007744|PDB:8ICY |
| Chain | Residue | Details |
| A | ARG149 | |
| A | SER180 | |
| A | GLY189 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:8841119, ECO:0007744|PDB:8ICX |
| Chain | Residue | Details |
| A | ARG183 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:9287163, ECO:0007744|PDB:1BPY |
| Chain | Residue | Details |
| A | ASP190 | |
| A | ASP192 | |
| A | ASP256 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q8K409 |
| Chain | Residue | Details |
| A | LYS72 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | MOD_RES: Omega-N-methylarginine; by PRMT6 => ECO:0000269|PubMed:16600869 |
| Chain | Residue | Details |
| A | ARG83 | |
| A | ARG152 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 4 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:19713937, ECO:0000269|PubMed:21362556 |
| Chain | Residue | Details |
| A | LYS41 | |
| A | LYS61 | |
| A | LYS81 |
