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8VAA

Actin-binding domain of Legionella pneumophila effector LFAT1 (lpg1387) bound to F-actin

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0001725cellular_componentstress fiber
A0005524molecular_functionATP binding
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0005856cellular_componentcytoskeleton
A0005865cellular_componentstriated muscle thin filament
A0005884cellular_componentactin filament
A0010628biological_processpositive regulation of gene expression
A0015629cellular_componentactin cytoskeleton
A0016787molecular_functionhydrolase activity
A0030017cellular_componentsarcomere
A0030027cellular_componentlamellipodium
A0030175cellular_componentfilopodium
A0030240biological_processskeletal muscle thin filament assembly
A0044297cellular_componentcell body
A0048741biological_processskeletal muscle fiber development
A0090131biological_processmesenchyme migration
B0000166molecular_functionnucleotide binding
B0001725cellular_componentstress fiber
B0005524molecular_functionATP binding
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0005856cellular_componentcytoskeleton
B0005865cellular_componentstriated muscle thin filament
B0005884cellular_componentactin filament
B0010628biological_processpositive regulation of gene expression
B0015629cellular_componentactin cytoskeleton
B0016787molecular_functionhydrolase activity
B0030017cellular_componentsarcomere
B0030027cellular_componentlamellipodium
B0030175cellular_componentfilopodium
B0030240biological_processskeletal muscle thin filament assembly
B0044297cellular_componentcell body
B0048741biological_processskeletal muscle fiber development
B0090131biological_processmesenchyme migration
C0000166molecular_functionnucleotide binding
C0001725cellular_componentstress fiber
C0005524molecular_functionATP binding
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0005856cellular_componentcytoskeleton
C0005865cellular_componentstriated muscle thin filament
C0005884cellular_componentactin filament
C0010628biological_processpositive regulation of gene expression
C0015629cellular_componentactin cytoskeleton
C0016787molecular_functionhydrolase activity
C0030017cellular_componentsarcomere
C0030027cellular_componentlamellipodium
C0030175cellular_componentfilopodium
C0030240biological_processskeletal muscle thin filament assembly
C0044297cellular_componentcell body
C0048741biological_processskeletal muscle fiber development
C0090131biological_processmesenchyme migration
D0000166molecular_functionnucleotide binding
D0001725cellular_componentstress fiber
D0005524molecular_functionATP binding
D0005737cellular_componentcytoplasm
D0005829cellular_componentcytosol
D0005856cellular_componentcytoskeleton
D0005865cellular_componentstriated muscle thin filament
D0005884cellular_componentactin filament
D0010628biological_processpositive regulation of gene expression
D0015629cellular_componentactin cytoskeleton
D0016787molecular_functionhydrolase activity
D0030017cellular_componentsarcomere
D0030027cellular_componentlamellipodium
D0030175cellular_componentfilopodium
D0030240biological_processskeletal muscle thin filament assembly
D0044297cellular_componentcell body
D0048741biological_processskeletal muscle fiber development
D0090131biological_processmesenchyme migration
E0000166molecular_functionnucleotide binding
E0001725cellular_componentstress fiber
E0005524molecular_functionATP binding
E0005737cellular_componentcytoplasm
E0005829cellular_componentcytosol
E0005856cellular_componentcytoskeleton
E0005865cellular_componentstriated muscle thin filament
E0005884cellular_componentactin filament
E0010628biological_processpositive regulation of gene expression
E0015629cellular_componentactin cytoskeleton
E0016787molecular_functionhydrolase activity
E0030017cellular_componentsarcomere
E0030027cellular_componentlamellipodium
E0030175cellular_componentfilopodium
E0030240biological_processskeletal muscle thin filament assembly
E0044297cellular_componentcell body
E0048741biological_processskeletal muscle fiber development
E0090131biological_processmesenchyme migration
F0000166molecular_functionnucleotide binding
F0001725cellular_componentstress fiber
F0005524molecular_functionATP binding
F0005737cellular_componentcytoplasm
F0005829cellular_componentcytosol
F0005856cellular_componentcytoskeleton
F0005865cellular_componentstriated muscle thin filament
F0005884cellular_componentactin filament
F0010628biological_processpositive regulation of gene expression
F0015629cellular_componentactin cytoskeleton
F0016787molecular_functionhydrolase activity
F0030017cellular_componentsarcomere
F0030027cellular_componentlamellipodium
F0030175cellular_componentfilopodium
F0030240biological_processskeletal muscle thin filament assembly
F0044297cellular_componentcell body
F0048741biological_processskeletal muscle fiber development
F0090131biological_processmesenchyme migration
G0000166molecular_functionnucleotide binding
G0001725cellular_componentstress fiber
G0005524molecular_functionATP binding
G0005737cellular_componentcytoplasm
G0005829cellular_componentcytosol
G0005856cellular_componentcytoskeleton
G0005865cellular_componentstriated muscle thin filament
G0005884cellular_componentactin filament
G0010628biological_processpositive regulation of gene expression
G0015629cellular_componentactin cytoskeleton
G0016787molecular_functionhydrolase activity
G0030017cellular_componentsarcomere
G0030027cellular_componentlamellipodium
G0030175cellular_componentfilopodium
G0030240biological_processskeletal muscle thin filament assembly
G0044297cellular_componentcell body
G0048741biological_processskeletal muscle fiber development
G0090131biological_processmesenchyme migration
H0000166molecular_functionnucleotide binding
H0001725cellular_componentstress fiber
H0005524molecular_functionATP binding
H0005737cellular_componentcytoplasm
H0005829cellular_componentcytosol
H0005856cellular_componentcytoskeleton
H0005865cellular_componentstriated muscle thin filament
H0005884cellular_componentactin filament
H0010628biological_processpositive regulation of gene expression
H0015629cellular_componentactin cytoskeleton
H0016787molecular_functionhydrolase activity
H0030017cellular_componentsarcomere
H0030027cellular_componentlamellipodium
H0030175cellular_componentfilopodium
H0030240biological_processskeletal muscle thin filament assembly
H0044297cellular_componentcell body
H0048741biological_processskeletal muscle fiber development
H0090131biological_processmesenchyme migration
I0000166molecular_functionnucleotide binding
I0001725cellular_componentstress fiber
I0005524molecular_functionATP binding
I0005737cellular_componentcytoplasm
I0005829cellular_componentcytosol
I0005856cellular_componentcytoskeleton
I0005865cellular_componentstriated muscle thin filament
I0005884cellular_componentactin filament
I0010628biological_processpositive regulation of gene expression
I0015629cellular_componentactin cytoskeleton
I0016787molecular_functionhydrolase activity
I0030017cellular_componentsarcomere
I0030027cellular_componentlamellipodium
I0030175cellular_componentfilopodium
I0030240biological_processskeletal muscle thin filament assembly
I0044297cellular_componentcell body
I0048741biological_processskeletal muscle fiber development
I0090131biological_processmesenchyme migration
J0000166molecular_functionnucleotide binding
J0001725cellular_componentstress fiber
J0005524molecular_functionATP binding
J0005737cellular_componentcytoplasm
J0005829cellular_componentcytosol
J0005856cellular_componentcytoskeleton
J0005865cellular_componentstriated muscle thin filament
J0005884cellular_componentactin filament
J0010628biological_processpositive regulation of gene expression
J0015629cellular_componentactin cytoskeleton
J0016787molecular_functionhydrolase activity
J0030017cellular_componentsarcomere
J0030027cellular_componentlamellipodium
J0030175cellular_componentfilopodium
J0030240biological_processskeletal muscle thin filament assembly
J0044297cellular_componentcell body
J0048741biological_processskeletal muscle fiber development
J0090131biological_processmesenchyme migration
Functional Information from PROSITE/UniProt
site_idPS00406
Number of Residues11
DetailsACTINS_1 Actins signature 1. YVGDEAQs.KRG
ChainResidueDetails
ATYR55-GLY65

site_idPS00432
Number of Residues9
DetailsACTINS_2 Actins signature 2. WITKqEYDE
ChainResidueDetails
ATRP358-GLU366

site_idPS01132
Number of Residues13
DetailsACTINS_ACT_LIKE Actins and actin-related proteins signature. LLTEApLNPkaNR
ChainResidueDetails
ALEU106-ARG118

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues20
DetailsMOD_RES: Methionine (R)-sulfoxide => ECO:0000250|UniProtKB:P68134
ChainResidueDetails
AMET46
EMET49
FMET46
FMET49
GMET46
GMET49
HMET46
HMET49
IMET46
IMET49
JMET46
AMET49
JMET49
BMET46
BMET49
CMET46
CMET49
DMET46
DMET49
EMET46

site_idSWS_FT_FI2
Number of Residues10
DetailsMOD_RES: N6-malonyllysine => ECO:0000250
ChainResidueDetails
ALYS63
JLYS63
BLYS63
CLYS63
DLYS63
ELYS63
FLYS63
GLYS63
HLYS63
ILYS63

site_idSWS_FT_FI3
Number of Residues10
DetailsMOD_RES: Tele-methylhistidine => ECO:0000269|PubMed:499690
ChainResidueDetails
AHIS75
JHIS75
BHIS75
CHIS75
DHIS75
EHIS75
FHIS75
GHIS75
HHIS75
IHIS75

site_idSWS_FT_FI4
Number of Residues10
DetailsMOD_RES: N6-methyllysine => ECO:0000250|UniProtKB:P68133
ChainResidueDetails
ALYS86
JLYS86
BLYS86
CLYS86
DLYS86
ELYS86
FLYS86
GLYS86
HLYS86
ILYS86

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PDB entries from 2025-06-11

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