8V4S
Cryo-EM structure of the rat P2X7 receptor in the apo closed state purified in the absence of sodium
Functional Information from PROSITE/UniProt
| site_id | PS01212 |
| Number of Residues | 27 |
| Details | P2X_RECEPTOR ATP P2X receptors signature. GGiMGIeIyWdCNLDswshrCqPkYsF |
| Chain | Residue | Details |
| A | GLY249-PHE275 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 789 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| A | MET1-ASN25 | |
| A | ASN356-TYR595 | |
| B | MET1-ASN25 | |
| B | ASN356-TYR595 | |
| C | MET1-ASN25 | |
| C | ASN356-TYR595 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 60 |
| Details | TRANSMEM: Helical; Name=1 => ECO:0000255 |
| Chain | Residue | Details |
| A | TYR26-MET46 | |
| B | TYR26-MET46 | |
| C | TYR26-MET46 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 861 |
| Details | TOPO_DOM: Extracellular => ECO:0000255 |
| Chain | Residue | Details |
| A | SER47-VAL334 | |
| B | SER47-VAL334 | |
| C | SER47-VAL334 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 60 |
| Details | TRANSMEM: Helical; Name=2 => ECO:0000255 |
| Chain | Residue | Details |
| A | VAL335-ILE355 | |
| B | VAL335-ILE355 | |
| C | VAL335-ILE355 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | MOD_RES: ADP-ribosylarginine => ECO:0000250 |
| Chain | Residue | Details |
| A | ARG125 | |
| B | ARG125 | |
| C | ARG125 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 12 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN74 | |
| C | ASN202 | |
| C | ASN241 | |
| C | ASN284 | |
| A | ASN202 | |
| A | ASN241 | |
| A | ASN284 | |
| B | ASN74 | |
| B | ASN202 | |
| B | ASN241 | |
| B | ASN284 | |
| C | ASN74 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 6 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0007744|PubMed:24090084 |
| Chain | Residue | Details |
| A | ASN187 | |
| A | ASN213 | |
| B | ASN187 | |
| B | ASN213 | |
| C | ASN187 | |
| C | ASN213 |
