8V1Y

Composite map of AMPylated GlnA bound to hinT

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003824	molecular_function	catalytic activity
A	0004356	molecular_function	glutamine synthetase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006541	biological_process	glutamine metabolic process
A	0006542	biological_process	glutamine biosynthetic process
A	0009314	biological_process	response to radiation
A	0016020	cellular_component	membrane
A	0016874	molecular_function	ligase activity
A	0019676	biological_process	ammonia assimilation cycle
A	0019740	biological_process	nitrogen utilization
A	0042802	molecular_function	identical protein binding
A	0046872	molecular_function	metal ion binding
B	0000166	molecular_function	nucleotide binding
B	0003824	molecular_function	catalytic activity
B	0004356	molecular_function	glutamine synthetase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006541	biological_process	glutamine metabolic process
B	0006542	biological_process	glutamine biosynthetic process
B	0009314	biological_process	response to radiation
B	0016020	cellular_component	membrane
B	0016874	molecular_function	ligase activity
B	0019676	biological_process	ammonia assimilation cycle
B	0019740	biological_process	nitrogen utilization
B	0042802	molecular_function	identical protein binding
B	0046872	molecular_function	metal ion binding
C	0000166	molecular_function	nucleotide binding
C	0003824	molecular_function	catalytic activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0016787	molecular_function	hydrolase activity
C	0042803	molecular_function	protein homodimerization activity
C	0043530	molecular_function	adenosine 5'-monophosphoramidase activity
C	0055130	biological_process	D-alanine catabolic process
D	0000166	molecular_function	nucleotide binding
D	0003824	molecular_function	catalytic activity
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0016787	molecular_function	hydrolase activity
D	0042803	molecular_function	protein homodimerization activity
D	0043530	molecular_function	adenosine 5'-monophosphoramidase activity
D	0055130	biological_process	D-alanine catabolic process

Functional Information from PROSITE/UniProt

site_id	PS00180
Number of Residues	19
Details	GLNA_1 Glutamine synthetase signature 1. FDGSSiggwkginESDmvL

Chain	Residue	Details
A	PHE50-LEU68

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site_id	PS00181
Number of Residues	16
Details	GLNA_ATP Glutamine synthetase putative ATP-binding region signature. KPMfgd..NGSGmHchmS

Chain	Residue	Details
A	LYS259-SER274

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site_id	PS00182
Number of Residues	13
Details	GLNA_ADENYLATION Glutamine synthetase class-I adenylation site. KIhpgeaMDKNLY

Chain	Residue	Details
A	LYS386-TYR398

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Tele-AMP-histidine intermediate => ECO:0000269|PubMed:15703176, ECO:0000269|PubMed:20934431

Chain	Residue	Details
C	ASN101
B	GLU132
B	GLU213
B	GLU221
B	HIS270
B	ARG340
B	ARG345
B	GLU358
D	ASN101
A	GLU213
A	GLU221
A	HIS270
A	ARG340
A	ARG345
A	GLU358
B	GLU130

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site_id	SWS_FT_FI2
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:20934431, ECO:0007744|PDB:3N1S

Chain	Residue	Details
C	ARG30
B	ARG322
B	GLU328
B	ARG360
C	ASN88
C	GLU96
C	ASN101
D	ARG30
D	ASN88
D	GLU96
D	ASN101
B	HIS272

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P12425

Chain	Residue	Details
A	GLY266
B	GLY266

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site_id	SWS_FT_FI4
Number of Residues	4
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P77961

Chain	Residue	Details
A	SER274
A	LYS353
B	SER274
B	LYS353

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site_id	SWS_FT_FI5
Number of Residues	2
Details	MOD_RES: O-AMP-tyrosine => ECO:0000269|PubMed:4904088, ECO:0000269|PubMed:5543675

Chain	Residue	Details
A	TYR398
B	TYR398

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