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8USP

Structural and biochemical investigations of a HEAT-repeat protein involved in the cytosolic iron-sulfur cluster assembly pathway

Functional Information from GO Data
ChainGOidnamespacecontents
A0003674molecular_functionmolecular_function
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006281biological_processDNA repair
A0006351biological_processDNA-templated transcription
A0006974biological_processDNA damage response
A0016226biological_processiron-sulfur cluster assembly
A0051604biological_processprotein maturation
A0097361cellular_componentcytosolic [4Fe-4S] assembly targeting complex
B0003674molecular_functionmolecular_function
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0006281biological_processDNA repair
B0006351biological_processDNA-templated transcription
B0006974biological_processDNA damage response
B0016226biological_processiron-sulfur cluster assembly
B0051604biological_processprotein maturation
B0097361cellular_componentcytosolic [4Fe-4S] assembly targeting complex
C0003674molecular_functionmolecular_function
C0005515molecular_functionprotein binding
C0005634cellular_componentnucleus
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0006281biological_processDNA repair
C0006351biological_processDNA-templated transcription
C0006974biological_processDNA damage response
C0016226biological_processiron-sulfur cluster assembly
C0051604biological_processprotein maturation
C0097361cellular_componentcytosolic [4Fe-4S] assembly targeting complex
D0003674molecular_functionmolecular_function
D0005515molecular_functionprotein binding
D0005634cellular_componentnucleus
D0005737cellular_componentcytoplasm
D0005829cellular_componentcytosol
D0006281biological_processDNA repair
D0006351biological_processDNA-templated transcription
D0006974biological_processDNA damage response
D0016226biological_processiron-sulfur cluster assembly
D0051604biological_processprotein maturation
D0097361cellular_componentcytosolic [4Fe-4S] assembly targeting complex
E0003674molecular_functionmolecular_function
E0005515molecular_functionprotein binding
E0005634cellular_componentnucleus
E0005737cellular_componentcytoplasm
E0005829cellular_componentcytosol
E0006281biological_processDNA repair
E0006351biological_processDNA-templated transcription
E0006974biological_processDNA damage response
E0016226biological_processiron-sulfur cluster assembly
E0051604biological_processprotein maturation
E0097361cellular_componentcytosolic [4Fe-4S] assembly targeting complex
F0003674molecular_functionmolecular_function
F0005515molecular_functionprotein binding
F0005634cellular_componentnucleus
F0005737cellular_componentcytoplasm
F0005829cellular_componentcytosol
F0006281biological_processDNA repair
F0006351biological_processDNA-templated transcription
F0006974biological_processDNA damage response
F0016226biological_processiron-sulfur cluster assembly
F0051604biological_processprotein maturation
F0097361cellular_componentcytosolic [4Fe-4S] assembly targeting complex
Functional Information from PROSITE/UniProt
site_idPS00324
Number of Residues9
DetailsASPARTOKINASE Aspartokinase signature. VrKFGGSSI
ChainResidueDetails
AVAL288-ILE296

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues234
DetailsRepeat: {"description":"HEAT 1"}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues228
DetailsRepeat: {"description":"HEAT 2"}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues252
DetailsRepeat: {"description":"HEAT 3"}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues228
DetailsRepeat: {"description":"HEAT 4"}
ChainResidueDetails

247536

PDB entries from 2026-01-14

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