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8UNJ

Atomic model of the human CTF18-RFC alone in the apo state (State 1)

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0003677molecular_functionDNA binding
A0003689molecular_functionDNA clamp loader activity
A0005515molecular_functionprotein binding
A0005524molecular_functionATP binding
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0005694cellular_componentchromosome
A0005737cellular_componentcytoplasm
A0006260biological_processDNA replication
A0016020cellular_componentmembrane
A0016887molecular_functionATP hydrolysis activity
A0017116molecular_functionsingle-stranded DNA helicase activity
A0031390cellular_componentCtf18 RFC-like complex
A1900264biological_processpositive regulation of DNA-directed DNA polymerase activity
B0000076biological_processDNA replication checkpoint signaling
B0000166molecular_functionnucleotide binding
B0003677molecular_functionDNA binding
B0003689molecular_functionDNA clamp loader activity
B0005515molecular_functionprotein binding
B0005524molecular_functionATP binding
B0005634cellular_componentnucleus
B0005654cellular_componentnucleoplasm
B0005663cellular_componentDNA replication factor C complex
B0005694cellular_componentchromosome
B0006260biological_processDNA replication
B0006261biological_processDNA-templated DNA replication
B0006281biological_processDNA repair
B0016887molecular_functionATP hydrolysis activity
B0017116molecular_functionsingle-stranded DNA helicase activity
B0019899molecular_functionenzyme binding
B0031390cellular_componentCtf18 RFC-like complex
B1900264biological_processpositive regulation of DNA-directed DNA polymerase activity
C0000076biological_processDNA replication checkpoint signaling
C0000166molecular_functionnucleotide binding
C0003677molecular_functionDNA binding
C0003689molecular_functionDNA clamp loader activity
C0005515molecular_functionprotein binding
C0005524molecular_functionATP binding
C0005634cellular_componentnucleus
C0005654cellular_componentnucleoplasm
C0005663cellular_componentDNA replication factor C complex
C0005694cellular_componentchromosome
C0006260biological_processDNA replication
C0006261biological_processDNA-templated DNA replication
C0006281biological_processDNA repair
C0016887molecular_functionATP hydrolysis activity
C0017116molecular_functionsingle-stranded DNA helicase activity
C0019899molecular_functionenzyme binding
C0031390cellular_componentCtf18 RFC-like complex
C1900264biological_processpositive regulation of DNA-directed DNA polymerase activity
D0000076biological_processDNA replication checkpoint signaling
D0000166molecular_functionnucleotide binding
D0003677molecular_functionDNA binding
D0003689molecular_functionDNA clamp loader activity
D0005515molecular_functionprotein binding
D0005524molecular_functionATP binding
D0005634cellular_componentnucleus
D0005654cellular_componentnucleoplasm
D0005663cellular_componentDNA replication factor C complex
D0005694cellular_componentchromosome
D0006260biological_processDNA replication
D0006261biological_processDNA-templated DNA replication
D0006271biological_processDNA strand elongation involved in DNA replication
D0006281biological_processDNA repair
D0016887molecular_functionATP hydrolysis activity
D0017116molecular_functionsingle-stranded DNA helicase activity
D0019899molecular_functionenzyme binding
D0031390cellular_componentCtf18 RFC-like complex
D0031391cellular_componentElg1 RFC-like complex
D1900264biological_processpositive regulation of DNA-directed DNA polymerase activity
E0000076biological_processDNA replication checkpoint signaling
E0000731biological_processDNA synthesis involved in DNA repair
E0003677molecular_functionDNA binding
E0003689molecular_functionDNA clamp loader activity
E0005515molecular_functionprotein binding
E0005634cellular_componentnucleus
E0005654cellular_componentnucleoplasm
E0005663cellular_componentDNA replication factor C complex
E0005694cellular_componentchromosome
E0006260biological_processDNA replication
E0006261biological_processDNA-templated DNA replication
E0006271biological_processDNA strand elongation involved in DNA replication
E0006281biological_processDNA repair
E0008094molecular_functionATP-dependent activity, acting on DNA
E0017116molecular_functionsingle-stranded DNA helicase activity
E0031390cellular_componentCtf18 RFC-like complex
E0032991cellular_componentprotein-containing complex
E1900264biological_processpositive regulation of DNA-directed DNA polymerase activity
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues21
DetailsBinding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues3
DetailsModified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues1
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17525332","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

247536

PDB entries from 2026-01-14

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