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8UIE

Structure of recombinantly assembled murine alpha-synuclein fibrils

Functional Information from GO Data
ChainGOidnamespacecontents
A0000149molecular_functionSNARE binding
A0000287molecular_functionmagnesium ion binding
A0001774biological_processmicroglial cell activation
A0001921biological_processpositive regulation of receptor recycling
A0001956biological_processpositive regulation of neurotransmitter secretion
A0001963biological_processsynaptic transmission, dopaminergic
A0003779molecular_functionactin binding
A0005507molecular_functioncopper ion binding
A0005509molecular_functioncalcium ion binding
A0005515molecular_functionprotein binding
A0005543molecular_functionphospholipid binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0005739cellular_componentmitochondrion
A0005829cellular_componentcytosol
A0005856cellular_componentcytoskeleton
A0005886cellular_componentplasma membrane
A0005938cellular_componentcell cortex
A0006631biological_processfatty acid metabolic process
A0006638biological_processneutral lipid metabolic process
A0006644biological_processphospholipid metabolic process
A0007006biological_processmitochondrial membrane organization
A0007268biological_processchemical synaptic transmission
A0007269biological_processneurotransmitter secretion
A0008198molecular_functionferrous iron binding
A0008270molecular_functionzinc ion binding
A0008289molecular_functionlipid binding
A0008344biological_processadult locomotory behavior
A0009410biological_processresponse to xenobiotic stimulus
A0010040biological_processresponse to iron(II) ion
A0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
A0014048biological_processregulation of glutamate secretion
A0014059biological_processregulation of dopamine secretion
A0015629cellular_componentactin cytoskeleton
A0016020cellular_componentmembrane
A0016079biological_processsynaptic vesicle exocytosis
A0016082biological_processsynaptic vesicle priming
A0016234cellular_componentinclusion body
A0016491molecular_functionoxidoreductase activity
A0019894molecular_functionkinesin binding
A0030424cellular_componentaxon
A0030426cellular_componentgrowth cone
A0030544molecular_functionHsp70 protein binding
A0030672cellular_componentsynaptic vesicle membrane
A0031092cellular_componentplatelet alpha granule membrane
A0031115biological_processnegative regulation of microtubule polymerization
A0031623biological_processreceptor internalization
A0031648biological_processprotein destabilization
A0032026biological_processresponse to magnesium ion
A0032496biological_processresponse to lipopolysaccharide
A0032991cellular_componentprotein-containing complex
A0033138biological_processpositive regulation of peptidyl-serine phosphorylation
A0034341biological_processresponse to type II interferon
A0034599biological_processcellular response to oxidative stress
A0035493biological_processSNARE complex assembly
A0035543biological_processpositive regulation of SNARE complex assembly
A0040012biological_processregulation of locomotion
A0042393molecular_functionhistone binding
A0042416biological_processdopamine biosynthetic process
A0042417biological_processdopamine metabolic process
A0042775biological_processmitochondrial ATP synthesis coupled electron transport
A0042802molecular_functionidentical protein binding
A0042995cellular_componentcell projection
A0043014molecular_functionalpha-tubulin binding
A0043025cellular_componentneuronal cell body
A0043027molecular_functioncysteine-type endopeptidase inhibitor activity involved in apoptotic process
A0043030biological_processregulation of macrophage activation
A0043066biological_processnegative regulation of apoptotic process
A0043524biological_processnegative regulation of neuron apoptotic process
A0043679cellular_componentaxon terminus
A0045202cellular_componentsynapse
A0045807biological_processpositive regulation of endocytosis
A0045920biological_processnegative regulation of exocytosis
A0045921biological_processpositive regulation of exocytosis
A0046872molecular_functionmetal ion binding
A0046928biological_processregulation of neurotransmitter secretion
A0048156molecular_functiontau protein binding
A0048168biological_processregulation of neuronal synaptic plasticity
A0048169biological_processregulation of long-term neuronal synaptic plasticity
A0048471cellular_componentperinuclear region of cytoplasm
A0048488biological_processsynaptic vesicle endocytosis
A0048489biological_processsynaptic vesicle transport
A0050544molecular_functionarachidonate binding
A0050729biological_processpositive regulation of inflammatory response
A0050806biological_processpositive regulation of synaptic transmission
A0050808biological_processsynapse organization
A0050812biological_processregulation of acyl-CoA biosynthetic process
A0051219molecular_functionphosphoprotein binding
A0051259biological_processprotein complex oligomerization
A0051262biological_processprotein tetramerization
A0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
A0051402biological_processneuron apoptotic process
A0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
A0051612biological_processnegative regulation of serotonin uptake
A0051621biological_processregulation of norepinephrine uptake
A0051622biological_processnegative regulation of norepinephrine uptake
A0060079biological_processexcitatory postsynaptic potential
A0060291biological_processlong-term synaptic potentiation
A0060732biological_processpositive regulation of inositol phosphate biosynthetic process
A0061024biological_processmembrane organization
A0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
A0070555biological_processresponse to interleukin-1
A0070840molecular_functiondynein complex binding
A0071280biological_processcellular response to copper ion
A0098794cellular_componentpostsynapse
A0099512cellular_componentsupramolecular fiber
A1903136molecular_functioncuprous ion binding
A1903285biological_processpositive regulation of hydrogen peroxide catabolic process
A1904377biological_processpositive regulation of protein localization to cell periphery
A1904715biological_processnegative regulation of chaperone-mediated autophagy
A1905606biological_processregulation of presynapse assembly
A2000377biological_processregulation of reactive oxygen species metabolic process
B0000149molecular_functionSNARE binding
B0000287molecular_functionmagnesium ion binding
B0001774biological_processmicroglial cell activation
B0001921biological_processpositive regulation of receptor recycling
B0001956biological_processpositive regulation of neurotransmitter secretion
B0001963biological_processsynaptic transmission, dopaminergic
B0003779molecular_functionactin binding
B0005507molecular_functioncopper ion binding
B0005509molecular_functioncalcium ion binding
B0005515molecular_functionprotein binding
B0005543molecular_functionphospholipid binding
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0005634cellular_componentnucleus
B0005737cellular_componentcytoplasm
B0005739cellular_componentmitochondrion
B0005829cellular_componentcytosol
B0005856cellular_componentcytoskeleton
B0005886cellular_componentplasma membrane
B0005938cellular_componentcell cortex
B0006631biological_processfatty acid metabolic process
B0006638biological_processneutral lipid metabolic process
B0006644biological_processphospholipid metabolic process
B0007006biological_processmitochondrial membrane organization
B0007268biological_processchemical synaptic transmission
B0007269biological_processneurotransmitter secretion
B0008198molecular_functionferrous iron binding
B0008270molecular_functionzinc ion binding
B0008289molecular_functionlipid binding
B0008344biological_processadult locomotory behavior
B0009410biological_processresponse to xenobiotic stimulus
B0010040biological_processresponse to iron(II) ion
B0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
B0014048biological_processregulation of glutamate secretion
B0014059biological_processregulation of dopamine secretion
B0015629cellular_componentactin cytoskeleton
B0016020cellular_componentmembrane
B0016079biological_processsynaptic vesicle exocytosis
B0016082biological_processsynaptic vesicle priming
B0016234cellular_componentinclusion body
B0016491molecular_functionoxidoreductase activity
B0019894molecular_functionkinesin binding
B0030424cellular_componentaxon
B0030426cellular_componentgrowth cone
B0030544molecular_functionHsp70 protein binding
B0030672cellular_componentsynaptic vesicle membrane
B0031092cellular_componentplatelet alpha granule membrane
B0031115biological_processnegative regulation of microtubule polymerization
B0031623biological_processreceptor internalization
B0031648biological_processprotein destabilization
B0032026biological_processresponse to magnesium ion
B0032496biological_processresponse to lipopolysaccharide
B0032991cellular_componentprotein-containing complex
B0033138biological_processpositive regulation of peptidyl-serine phosphorylation
B0034341biological_processresponse to type II interferon
B0034599biological_processcellular response to oxidative stress
B0035493biological_processSNARE complex assembly
B0035543biological_processpositive regulation of SNARE complex assembly
B0040012biological_processregulation of locomotion
B0042393molecular_functionhistone binding
B0042416biological_processdopamine biosynthetic process
B0042417biological_processdopamine metabolic process
B0042775biological_processmitochondrial ATP synthesis coupled electron transport
B0042802molecular_functionidentical protein binding
B0042995cellular_componentcell projection
B0043014molecular_functionalpha-tubulin binding
B0043025cellular_componentneuronal cell body
B0043027molecular_functioncysteine-type endopeptidase inhibitor activity involved in apoptotic process
B0043030biological_processregulation of macrophage activation
B0043066biological_processnegative regulation of apoptotic process
B0043524biological_processnegative regulation of neuron apoptotic process
B0043679cellular_componentaxon terminus
B0045202cellular_componentsynapse
B0045807biological_processpositive regulation of endocytosis
B0045920biological_processnegative regulation of exocytosis
B0045921biological_processpositive regulation of exocytosis
B0046872molecular_functionmetal ion binding
B0046928biological_processregulation of neurotransmitter secretion
B0048156molecular_functiontau protein binding
B0048168biological_processregulation of neuronal synaptic plasticity
B0048169biological_processregulation of long-term neuronal synaptic plasticity
B0048471cellular_componentperinuclear region of cytoplasm
B0048488biological_processsynaptic vesicle endocytosis
B0048489biological_processsynaptic vesicle transport
B0050544molecular_functionarachidonate binding
B0050729biological_processpositive regulation of inflammatory response
B0050806biological_processpositive regulation of synaptic transmission
B0050808biological_processsynapse organization
B0050812biological_processregulation of acyl-CoA biosynthetic process
B0051219molecular_functionphosphoprotein binding
B0051259biological_processprotein complex oligomerization
B0051262biological_processprotein tetramerization
B0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
B0051402biological_processneuron apoptotic process
B0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
B0051612biological_processnegative regulation of serotonin uptake
B0051621biological_processregulation of norepinephrine uptake
B0051622biological_processnegative regulation of norepinephrine uptake
B0060079biological_processexcitatory postsynaptic potential
B0060291biological_processlong-term synaptic potentiation
B0060732biological_processpositive regulation of inositol phosphate biosynthetic process
B0061024biological_processmembrane organization
B0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
B0070555biological_processresponse to interleukin-1
B0070840molecular_functiondynein complex binding
B0071280biological_processcellular response to copper ion
B0098794cellular_componentpostsynapse
B0099512cellular_componentsupramolecular fiber
B1903136molecular_functioncuprous ion binding
B1903285biological_processpositive regulation of hydrogen peroxide catabolic process
B1904377biological_processpositive regulation of protein localization to cell periphery
B1904715biological_processnegative regulation of chaperone-mediated autophagy
B1905606biological_processregulation of presynapse assembly
B2000377biological_processregulation of reactive oxygen species metabolic process
D0000149molecular_functionSNARE binding
D0000287molecular_functionmagnesium ion binding
D0001774biological_processmicroglial cell activation
D0001921biological_processpositive regulation of receptor recycling
D0001956biological_processpositive regulation of neurotransmitter secretion
D0001963biological_processsynaptic transmission, dopaminergic
D0003779molecular_functionactin binding
D0005507molecular_functioncopper ion binding
D0005509molecular_functioncalcium ion binding
D0005515molecular_functionprotein binding
D0005543molecular_functionphospholipid binding
D0005576cellular_componentextracellular region
D0005615cellular_componentextracellular space
D0005634cellular_componentnucleus
D0005737cellular_componentcytoplasm
D0005739cellular_componentmitochondrion
D0005829cellular_componentcytosol
D0005856cellular_componentcytoskeleton
D0005886cellular_componentplasma membrane
D0005938cellular_componentcell cortex
D0006631biological_processfatty acid metabolic process
D0006638biological_processneutral lipid metabolic process
D0006644biological_processphospholipid metabolic process
D0007006biological_processmitochondrial membrane organization
D0007268biological_processchemical synaptic transmission
D0007269biological_processneurotransmitter secretion
D0008198molecular_functionferrous iron binding
D0008270molecular_functionzinc ion binding
D0008289molecular_functionlipid binding
D0008344biological_processadult locomotory behavior
D0009410biological_processresponse to xenobiotic stimulus
D0010040biological_processresponse to iron(II) ion
D0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
D0014048biological_processregulation of glutamate secretion
D0014059biological_processregulation of dopamine secretion
D0015629cellular_componentactin cytoskeleton
D0016020cellular_componentmembrane
D0016079biological_processsynaptic vesicle exocytosis
D0016082biological_processsynaptic vesicle priming
D0016234cellular_componentinclusion body
D0016491molecular_functionoxidoreductase activity
D0019894molecular_functionkinesin binding
D0030424cellular_componentaxon
D0030426cellular_componentgrowth cone
D0030544molecular_functionHsp70 protein binding
D0030672cellular_componentsynaptic vesicle membrane
D0031092cellular_componentplatelet alpha granule membrane
D0031115biological_processnegative regulation of microtubule polymerization
D0031623biological_processreceptor internalization
D0031648biological_processprotein destabilization
D0032026biological_processresponse to magnesium ion
D0032496biological_processresponse to lipopolysaccharide
D0032991cellular_componentprotein-containing complex
D0033138biological_processpositive regulation of peptidyl-serine phosphorylation
D0034341biological_processresponse to type II interferon
D0034599biological_processcellular response to oxidative stress
D0035493biological_processSNARE complex assembly
D0035543biological_processpositive regulation of SNARE complex assembly
D0040012biological_processregulation of locomotion
D0042393molecular_functionhistone binding
D0042416biological_processdopamine biosynthetic process
D0042417biological_processdopamine metabolic process
D0042775biological_processmitochondrial ATP synthesis coupled electron transport
D0042802molecular_functionidentical protein binding
D0042995cellular_componentcell projection
D0043014molecular_functionalpha-tubulin binding
D0043025cellular_componentneuronal cell body
D0043027molecular_functioncysteine-type endopeptidase inhibitor activity involved in apoptotic process
D0043030biological_processregulation of macrophage activation
D0043066biological_processnegative regulation of apoptotic process
D0043524biological_processnegative regulation of neuron apoptotic process
D0043679cellular_componentaxon terminus
D0045202cellular_componentsynapse
D0045807biological_processpositive regulation of endocytosis
D0045920biological_processnegative regulation of exocytosis
D0045921biological_processpositive regulation of exocytosis
D0046872molecular_functionmetal ion binding
D0046928biological_processregulation of neurotransmitter secretion
D0048156molecular_functiontau protein binding
D0048168biological_processregulation of neuronal synaptic plasticity
D0048169biological_processregulation of long-term neuronal synaptic plasticity
D0048471cellular_componentperinuclear region of cytoplasm
D0048488biological_processsynaptic vesicle endocytosis
D0048489biological_processsynaptic vesicle transport
D0050544molecular_functionarachidonate binding
D0050729biological_processpositive regulation of inflammatory response
D0050806biological_processpositive regulation of synaptic transmission
D0050808biological_processsynapse organization
D0050812biological_processregulation of acyl-CoA biosynthetic process
D0051219molecular_functionphosphoprotein binding
D0051259biological_processprotein complex oligomerization
D0051262biological_processprotein tetramerization
D0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
D0051402biological_processneuron apoptotic process
D0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
D0051612biological_processnegative regulation of serotonin uptake
D0051621biological_processregulation of norepinephrine uptake
D0051622biological_processnegative regulation of norepinephrine uptake
D0060079biological_processexcitatory postsynaptic potential
D0060291biological_processlong-term synaptic potentiation
D0060732biological_processpositive regulation of inositol phosphate biosynthetic process
D0061024biological_processmembrane organization
D0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
D0070555biological_processresponse to interleukin-1
D0070840molecular_functiondynein complex binding
D0071280biological_processcellular response to copper ion
D0098794cellular_componentpostsynapse
D0099512cellular_componentsupramolecular fiber
D1903136molecular_functioncuprous ion binding
D1903285biological_processpositive regulation of hydrogen peroxide catabolic process
D1904377biological_processpositive regulation of protein localization to cell periphery
D1904715biological_processnegative regulation of chaperone-mediated autophagy
D1905606biological_processregulation of presynapse assembly
D2000377biological_processregulation of reactive oxygen species metabolic process
E0000149molecular_functionSNARE binding
E0000287molecular_functionmagnesium ion binding
E0001774biological_processmicroglial cell activation
E0001921biological_processpositive regulation of receptor recycling
E0001956biological_processpositive regulation of neurotransmitter secretion
E0001963biological_processsynaptic transmission, dopaminergic
E0003779molecular_functionactin binding
E0005507molecular_functioncopper ion binding
E0005509molecular_functioncalcium ion binding
E0005515molecular_functionprotein binding
E0005543molecular_functionphospholipid binding
E0005576cellular_componentextracellular region
E0005615cellular_componentextracellular space
E0005634cellular_componentnucleus
E0005737cellular_componentcytoplasm
E0005739cellular_componentmitochondrion
E0005829cellular_componentcytosol
E0005856cellular_componentcytoskeleton
E0005886cellular_componentplasma membrane
E0005938cellular_componentcell cortex
E0006631biological_processfatty acid metabolic process
E0006638biological_processneutral lipid metabolic process
E0006644biological_processphospholipid metabolic process
E0007006biological_processmitochondrial membrane organization
E0007268biological_processchemical synaptic transmission
E0007269biological_processneurotransmitter secretion
E0008198molecular_functionferrous iron binding
E0008270molecular_functionzinc ion binding
E0008289molecular_functionlipid binding
E0008344biological_processadult locomotory behavior
E0009410biological_processresponse to xenobiotic stimulus
E0010040biological_processresponse to iron(II) ion
E0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
E0014048biological_processregulation of glutamate secretion
E0014059biological_processregulation of dopamine secretion
E0015629cellular_componentactin cytoskeleton
E0016020cellular_componentmembrane
E0016079biological_processsynaptic vesicle exocytosis
E0016082biological_processsynaptic vesicle priming
E0016234cellular_componentinclusion body
E0016491molecular_functionoxidoreductase activity
E0019894molecular_functionkinesin binding
E0030424cellular_componentaxon
E0030426cellular_componentgrowth cone
E0030544molecular_functionHsp70 protein binding
E0030672cellular_componentsynaptic vesicle membrane
E0031092cellular_componentplatelet alpha granule membrane
E0031115biological_processnegative regulation of microtubule polymerization
E0031623biological_processreceptor internalization
E0031648biological_processprotein destabilization
E0032026biological_processresponse to magnesium ion
E0032496biological_processresponse to lipopolysaccharide
E0032991cellular_componentprotein-containing complex
E0033138biological_processpositive regulation of peptidyl-serine phosphorylation
E0034341biological_processresponse to type II interferon
E0034599biological_processcellular response to oxidative stress
E0035493biological_processSNARE complex assembly
E0035543biological_processpositive regulation of SNARE complex assembly
E0040012biological_processregulation of locomotion
E0042393molecular_functionhistone binding
E0042416biological_processdopamine biosynthetic process
E0042417biological_processdopamine metabolic process
E0042775biological_processmitochondrial ATP synthesis coupled electron transport
E0042802molecular_functionidentical protein binding
E0042995cellular_componentcell projection
E0043014molecular_functionalpha-tubulin binding
E0043025cellular_componentneuronal cell body
E0043027molecular_functioncysteine-type endopeptidase inhibitor activity involved in apoptotic process
E0043030biological_processregulation of macrophage activation
E0043066biological_processnegative regulation of apoptotic process
E0043524biological_processnegative regulation of neuron apoptotic process
E0043679cellular_componentaxon terminus
E0045202cellular_componentsynapse
E0045807biological_processpositive regulation of endocytosis
E0045920biological_processnegative regulation of exocytosis
E0045921biological_processpositive regulation of exocytosis
E0046872molecular_functionmetal ion binding
E0046928biological_processregulation of neurotransmitter secretion
E0048156molecular_functiontau protein binding
E0048168biological_processregulation of neuronal synaptic plasticity
E0048169biological_processregulation of long-term neuronal synaptic plasticity
E0048471cellular_componentperinuclear region of cytoplasm
E0048488biological_processsynaptic vesicle endocytosis
E0048489biological_processsynaptic vesicle transport
E0050544molecular_functionarachidonate binding
E0050729biological_processpositive regulation of inflammatory response
E0050806biological_processpositive regulation of synaptic transmission
E0050808biological_processsynapse organization
E0050812biological_processregulation of acyl-CoA biosynthetic process
E0051219molecular_functionphosphoprotein binding
E0051259biological_processprotein complex oligomerization
E0051262biological_processprotein tetramerization
E0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
E0051402biological_processneuron apoptotic process
E0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
E0051612biological_processnegative regulation of serotonin uptake
E0051621biological_processregulation of norepinephrine uptake
E0051622biological_processnegative regulation of norepinephrine uptake
E0060079biological_processexcitatory postsynaptic potential
E0060291biological_processlong-term synaptic potentiation
E0060732biological_processpositive regulation of inositol phosphate biosynthetic process
E0061024biological_processmembrane organization
E0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
E0070555biological_processresponse to interleukin-1
E0070840molecular_functiondynein complex binding
E0071280biological_processcellular response to copper ion
E0098794cellular_componentpostsynapse
E0099512cellular_componentsupramolecular fiber
E1903136molecular_functioncuprous ion binding
E1903285biological_processpositive regulation of hydrogen peroxide catabolic process
E1904377biological_processpositive regulation of protein localization to cell periphery
E1904715biological_processnegative regulation of chaperone-mediated autophagy
E1905606biological_processregulation of presynapse assembly
E2000377biological_processregulation of reactive oxygen species metabolic process
F0000149molecular_functionSNARE binding
F0000287molecular_functionmagnesium ion binding
F0001774biological_processmicroglial cell activation
F0001921biological_processpositive regulation of receptor recycling
F0001956biological_processpositive regulation of neurotransmitter secretion
F0001963biological_processsynaptic transmission, dopaminergic
F0003779molecular_functionactin binding
F0005507molecular_functioncopper ion binding
F0005509molecular_functioncalcium ion binding
F0005515molecular_functionprotein binding
F0005543molecular_functionphospholipid binding
F0005576cellular_componentextracellular region
F0005615cellular_componentextracellular space
F0005634cellular_componentnucleus
F0005737cellular_componentcytoplasm
F0005739cellular_componentmitochondrion
F0005829cellular_componentcytosol
F0005856cellular_componentcytoskeleton
F0005886cellular_componentplasma membrane
F0005938cellular_componentcell cortex
F0006631biological_processfatty acid metabolic process
F0006638biological_processneutral lipid metabolic process
F0006644biological_processphospholipid metabolic process
F0007006biological_processmitochondrial membrane organization
F0007268biological_processchemical synaptic transmission
F0007269biological_processneurotransmitter secretion
F0008198molecular_functionferrous iron binding
F0008270molecular_functionzinc ion binding
F0008289molecular_functionlipid binding
F0008344biological_processadult locomotory behavior
F0009410biological_processresponse to xenobiotic stimulus
F0010040biological_processresponse to iron(II) ion
F0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
F0014048biological_processregulation of glutamate secretion
F0014059biological_processregulation of dopamine secretion
F0015629cellular_componentactin cytoskeleton
F0016020cellular_componentmembrane
F0016079biological_processsynaptic vesicle exocytosis
F0016082biological_processsynaptic vesicle priming
F0016234cellular_componentinclusion body
F0016491molecular_functionoxidoreductase activity
F0019894molecular_functionkinesin binding
F0030424cellular_componentaxon
F0030426cellular_componentgrowth cone
F0030544molecular_functionHsp70 protein binding
F0030672cellular_componentsynaptic vesicle membrane
F0031092cellular_componentplatelet alpha granule membrane
F0031115biological_processnegative regulation of microtubule polymerization
F0031623biological_processreceptor internalization
F0031648biological_processprotein destabilization
F0032026biological_processresponse to magnesium ion
F0032496biological_processresponse to lipopolysaccharide
F0032991cellular_componentprotein-containing complex
F0033138biological_processpositive regulation of peptidyl-serine phosphorylation
F0034341biological_processresponse to type II interferon
F0034599biological_processcellular response to oxidative stress
F0035493biological_processSNARE complex assembly
F0035543biological_processpositive regulation of SNARE complex assembly
F0040012biological_processregulation of locomotion
F0042393molecular_functionhistone binding
F0042416biological_processdopamine biosynthetic process
F0042417biological_processdopamine metabolic process
F0042775biological_processmitochondrial ATP synthesis coupled electron transport
F0042802molecular_functionidentical protein binding
F0042995cellular_componentcell projection
F0043014molecular_functionalpha-tubulin binding
F0043025cellular_componentneuronal cell body
F0043027molecular_functioncysteine-type endopeptidase inhibitor activity involved in apoptotic process
F0043030biological_processregulation of macrophage activation
F0043066biological_processnegative regulation of apoptotic process
F0043524biological_processnegative regulation of neuron apoptotic process
F0043679cellular_componentaxon terminus
F0045202cellular_componentsynapse
F0045807biological_processpositive regulation of endocytosis
F0045920biological_processnegative regulation of exocytosis
F0045921biological_processpositive regulation of exocytosis
F0046872molecular_functionmetal ion binding
F0046928biological_processregulation of neurotransmitter secretion
F0048156molecular_functiontau protein binding
F0048168biological_processregulation of neuronal synaptic plasticity
F0048169biological_processregulation of long-term neuronal synaptic plasticity
F0048471cellular_componentperinuclear region of cytoplasm
F0048488biological_processsynaptic vesicle endocytosis
F0048489biological_processsynaptic vesicle transport
F0050544molecular_functionarachidonate binding
F0050729biological_processpositive regulation of inflammatory response
F0050806biological_processpositive regulation of synaptic transmission
F0050808biological_processsynapse organization
F0050812biological_processregulation of acyl-CoA biosynthetic process
F0051219molecular_functionphosphoprotein binding
F0051259biological_processprotein complex oligomerization
F0051262biological_processprotein tetramerization
F0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
F0051402biological_processneuron apoptotic process
F0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
F0051612biological_processnegative regulation of serotonin uptake
F0051621biological_processregulation of norepinephrine uptake
F0051622biological_processnegative regulation of norepinephrine uptake
F0060079biological_processexcitatory postsynaptic potential
F0060291biological_processlong-term synaptic potentiation
F0060732biological_processpositive regulation of inositol phosphate biosynthetic process
F0061024biological_processmembrane organization
F0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
F0070555biological_processresponse to interleukin-1
F0070840molecular_functiondynein complex binding
F0071280biological_processcellular response to copper ion
F0098794cellular_componentpostsynapse
F0099512cellular_componentsupramolecular fiber
F1903136molecular_functioncuprous ion binding
F1903285biological_processpositive regulation of hydrogen peroxide catabolic process
F1904377biological_processpositive regulation of protein localization to cell periphery
F1904715biological_processnegative regulation of chaperone-mediated autophagy
F1905606biological_processregulation of presynapse assembly
F2000377biological_processregulation of reactive oxygen species metabolic process
G0000149molecular_functionSNARE binding
G0000287molecular_functionmagnesium ion binding
G0001774biological_processmicroglial cell activation
G0001921biological_processpositive regulation of receptor recycling
G0001956biological_processpositive regulation of neurotransmitter secretion
G0001963biological_processsynaptic transmission, dopaminergic
G0003779molecular_functionactin binding
G0005507molecular_functioncopper ion binding
G0005509molecular_functioncalcium ion binding
G0005515molecular_functionprotein binding
G0005543molecular_functionphospholipid binding
G0005576cellular_componentextracellular region
G0005615cellular_componentextracellular space
G0005634cellular_componentnucleus
G0005737cellular_componentcytoplasm
G0005739cellular_componentmitochondrion
G0005829cellular_componentcytosol
G0005856cellular_componentcytoskeleton
G0005886cellular_componentplasma membrane
G0005938cellular_componentcell cortex
G0006631biological_processfatty acid metabolic process
G0006638biological_processneutral lipid metabolic process
G0006644biological_processphospholipid metabolic process
G0007006biological_processmitochondrial membrane organization
G0007268biological_processchemical synaptic transmission
G0007269biological_processneurotransmitter secretion
G0008198molecular_functionferrous iron binding
G0008270molecular_functionzinc ion binding
G0008289molecular_functionlipid binding
G0008344biological_processadult locomotory behavior
G0009410biological_processresponse to xenobiotic stimulus
G0010040biological_processresponse to iron(II) ion
G0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
G0014048biological_processregulation of glutamate secretion
G0014059biological_processregulation of dopamine secretion
G0015629cellular_componentactin cytoskeleton
G0016020cellular_componentmembrane
G0016079biological_processsynaptic vesicle exocytosis
G0016082biological_processsynaptic vesicle priming
G0016234cellular_componentinclusion body
G0016491molecular_functionoxidoreductase activity
G0019894molecular_functionkinesin binding
G0030424cellular_componentaxon
G0030426cellular_componentgrowth cone
G0030544molecular_functionHsp70 protein binding
G0030672cellular_componentsynaptic vesicle membrane
G0031092cellular_componentplatelet alpha granule membrane
G0031115biological_processnegative regulation of microtubule polymerization
G0031623biological_processreceptor internalization
G0031648biological_processprotein destabilization
G0032026biological_processresponse to magnesium ion
G0032496biological_processresponse to lipopolysaccharide
G0032991cellular_componentprotein-containing complex
G0033138biological_processpositive regulation of peptidyl-serine phosphorylation
G0034341biological_processresponse to type II interferon
G0034599biological_processcellular response to oxidative stress
G0035493biological_processSNARE complex assembly
G0035543biological_processpositive regulation of SNARE complex assembly
G0040012biological_processregulation of locomotion
G0042393molecular_functionhistone binding
G0042416biological_processdopamine biosynthetic process
G0042417biological_processdopamine metabolic process
G0042775biological_processmitochondrial ATP synthesis coupled electron transport
G0042802molecular_functionidentical protein binding
G0042995cellular_componentcell projection
G0043014molecular_functionalpha-tubulin binding
G0043025cellular_componentneuronal cell body
G0043027molecular_functioncysteine-type endopeptidase inhibitor activity involved in apoptotic process
G0043030biological_processregulation of macrophage activation
G0043066biological_processnegative regulation of apoptotic process
G0043524biological_processnegative regulation of neuron apoptotic process
G0043679cellular_componentaxon terminus
G0045202cellular_componentsynapse
G0045807biological_processpositive regulation of endocytosis
G0045920biological_processnegative regulation of exocytosis
G0045921biological_processpositive regulation of exocytosis
G0046872molecular_functionmetal ion binding
G0046928biological_processregulation of neurotransmitter secretion
G0048156molecular_functiontau protein binding
G0048168biological_processregulation of neuronal synaptic plasticity
G0048169biological_processregulation of long-term neuronal synaptic plasticity
G0048471cellular_componentperinuclear region of cytoplasm
G0048488biological_processsynaptic vesicle endocytosis
G0048489biological_processsynaptic vesicle transport
G0050544molecular_functionarachidonate binding
G0050729biological_processpositive regulation of inflammatory response
G0050806biological_processpositive regulation of synaptic transmission
G0050808biological_processsynapse organization
G0050812biological_processregulation of acyl-CoA biosynthetic process
G0051219molecular_functionphosphoprotein binding
G0051259biological_processprotein complex oligomerization
G0051262biological_processprotein tetramerization
G0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
G0051402biological_processneuron apoptotic process
G0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
G0051612biological_processnegative regulation of serotonin uptake
G0051621biological_processregulation of norepinephrine uptake
G0051622biological_processnegative regulation of norepinephrine uptake
G0060079biological_processexcitatory postsynaptic potential
G0060291biological_processlong-term synaptic potentiation
G0060732biological_processpositive regulation of inositol phosphate biosynthetic process
G0061024biological_processmembrane organization
G0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
G0070555biological_processresponse to interleukin-1
G0070840molecular_functiondynein complex binding
G0071280biological_processcellular response to copper ion
G0098794cellular_componentpostsynapse
G0099512cellular_componentsupramolecular fiber
G1903136molecular_functioncuprous ion binding
G1903285biological_processpositive regulation of hydrogen peroxide catabolic process
G1904377biological_processpositive regulation of protein localization to cell periphery
G1904715biological_processnegative regulation of chaperone-mediated autophagy
G1905606biological_processregulation of presynapse assembly
G2000377biological_processregulation of reactive oxygen species metabolic process
H0000149molecular_functionSNARE binding
H0000287molecular_functionmagnesium ion binding
H0001774biological_processmicroglial cell activation
H0001921biological_processpositive regulation of receptor recycling
H0001956biological_processpositive regulation of neurotransmitter secretion
H0001963biological_processsynaptic transmission, dopaminergic
H0003779molecular_functionactin binding
H0005507molecular_functioncopper ion binding
H0005509molecular_functioncalcium ion binding
H0005515molecular_functionprotein binding
H0005543molecular_functionphospholipid binding
H0005576cellular_componentextracellular region
H0005615cellular_componentextracellular space
H0005634cellular_componentnucleus
H0005737cellular_componentcytoplasm
H0005739cellular_componentmitochondrion
H0005829cellular_componentcytosol
H0005856cellular_componentcytoskeleton
H0005886cellular_componentplasma membrane
H0005938cellular_componentcell cortex
H0006631biological_processfatty acid metabolic process
H0006638biological_processneutral lipid metabolic process
H0006644biological_processphospholipid metabolic process
H0007006biological_processmitochondrial membrane organization
H0007268biological_processchemical synaptic transmission
H0007269biological_processneurotransmitter secretion
H0008198molecular_functionferrous iron binding
H0008270molecular_functionzinc ion binding
H0008289molecular_functionlipid binding
H0008344biological_processadult locomotory behavior
H0009410biological_processresponse to xenobiotic stimulus
H0010040biological_processresponse to iron(II) ion
H0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
H0014048biological_processregulation of glutamate secretion
H0014059biological_processregulation of dopamine secretion
H0015629cellular_componentactin cytoskeleton
H0016020cellular_componentmembrane
H0016079biological_processsynaptic vesicle exocytosis
H0016082biological_processsynaptic vesicle priming
H0016234cellular_componentinclusion body
H0016491molecular_functionoxidoreductase activity
H0019894molecular_functionkinesin binding
H0030424cellular_componentaxon
H0030426cellular_componentgrowth cone
H0030544molecular_functionHsp70 protein binding
H0030672cellular_componentsynaptic vesicle membrane
H0031092cellular_componentplatelet alpha granule membrane
H0031115biological_processnegative regulation of microtubule polymerization
H0031623biological_processreceptor internalization
H0031648biological_processprotein destabilization
H0032026biological_processresponse to magnesium ion
H0032496biological_processresponse to lipopolysaccharide
H0032991cellular_componentprotein-containing complex
H0033138biological_processpositive regulation of peptidyl-serine phosphorylation
H0034341biological_processresponse to type II interferon
H0034599biological_processcellular response to oxidative stress
H0035493biological_processSNARE complex assembly
H0035543biological_processpositive regulation of SNARE complex assembly
H0040012biological_processregulation of locomotion
H0042393molecular_functionhistone binding
H0042416biological_processdopamine biosynthetic process
H0042417biological_processdopamine metabolic process
H0042775biological_processmitochondrial ATP synthesis coupled electron transport
H0042802molecular_functionidentical protein binding
H0042995cellular_componentcell projection
H0043014molecular_functionalpha-tubulin binding
H0043025cellular_componentneuronal cell body
H0043027molecular_functioncysteine-type endopeptidase inhibitor activity involved in apoptotic process
H0043030biological_processregulation of macrophage activation
H0043066biological_processnegative regulation of apoptotic process
H0043524biological_processnegative regulation of neuron apoptotic process
H0043679cellular_componentaxon terminus
H0045202cellular_componentsynapse
H0045807biological_processpositive regulation of endocytosis
H0045920biological_processnegative regulation of exocytosis
H0045921biological_processpositive regulation of exocytosis
H0046872molecular_functionmetal ion binding
H0046928biological_processregulation of neurotransmitter secretion
H0048156molecular_functiontau protein binding
H0048168biological_processregulation of neuronal synaptic plasticity
H0048169biological_processregulation of long-term neuronal synaptic plasticity
H0048471cellular_componentperinuclear region of cytoplasm
H0048488biological_processsynaptic vesicle endocytosis
H0048489biological_processsynaptic vesicle transport
H0050544molecular_functionarachidonate binding
H0050729biological_processpositive regulation of inflammatory response
H0050806biological_processpositive regulation of synaptic transmission
H0050808biological_processsynapse organization
H0050812biological_processregulation of acyl-CoA biosynthetic process
H0051219molecular_functionphosphoprotein binding
H0051259biological_processprotein complex oligomerization
H0051262biological_processprotein tetramerization
H0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
H0051402biological_processneuron apoptotic process
H0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
H0051612biological_processnegative regulation of serotonin uptake
H0051621biological_processregulation of norepinephrine uptake
H0051622biological_processnegative regulation of norepinephrine uptake
H0060079biological_processexcitatory postsynaptic potential
H0060291biological_processlong-term synaptic potentiation
H0060732biological_processpositive regulation of inositol phosphate biosynthetic process
H0061024biological_processmembrane organization
H0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
H0070555biological_processresponse to interleukin-1
H0070840molecular_functiondynein complex binding
H0071280biological_processcellular response to copper ion
H0098794cellular_componentpostsynapse
H0099512cellular_componentsupramolecular fiber
H1903136molecular_functioncuprous ion binding
H1903285biological_processpositive regulation of hydrogen peroxide catabolic process
H1904377biological_processpositive regulation of protein localization to cell periphery
H1904715biological_processnegative regulation of chaperone-mediated autophagy
H1905606biological_processregulation of presynapse assembly
H2000377biological_processregulation of reactive oxygen species metabolic process
I0000149molecular_functionSNARE binding
I0000287molecular_functionmagnesium ion binding
I0001774biological_processmicroglial cell activation
I0001921biological_processpositive regulation of receptor recycling
I0001956biological_processpositive regulation of neurotransmitter secretion
I0001963biological_processsynaptic transmission, dopaminergic
I0003779molecular_functionactin binding
I0005507molecular_functioncopper ion binding
I0005509molecular_functioncalcium ion binding
I0005515molecular_functionprotein binding
I0005543molecular_functionphospholipid binding
I0005576cellular_componentextracellular region
I0005615cellular_componentextracellular space
I0005634cellular_componentnucleus
I0005737cellular_componentcytoplasm
I0005739cellular_componentmitochondrion
I0005829cellular_componentcytosol
I0005856cellular_componentcytoskeleton
I0005886cellular_componentplasma membrane
I0005938cellular_componentcell cortex
I0006631biological_processfatty acid metabolic process
I0006638biological_processneutral lipid metabolic process
I0006644biological_processphospholipid metabolic process
I0007006biological_processmitochondrial membrane organization
I0007268biological_processchemical synaptic transmission
I0007269biological_processneurotransmitter secretion
I0008198molecular_functionferrous iron binding
I0008270molecular_functionzinc ion binding
I0008289molecular_functionlipid binding
I0008344biological_processadult locomotory behavior
I0009410biological_processresponse to xenobiotic stimulus
I0010040biological_processresponse to iron(II) ion
I0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
I0014048biological_processregulation of glutamate secretion
I0014059biological_processregulation of dopamine secretion
I0015629cellular_componentactin cytoskeleton
I0016020cellular_componentmembrane
I0016079biological_processsynaptic vesicle exocytosis
I0016082biological_processsynaptic vesicle priming
I0016234cellular_componentinclusion body
I0016491molecular_functionoxidoreductase activity
I0019894molecular_functionkinesin binding
I0030424cellular_componentaxon
I0030426cellular_componentgrowth cone
I0030544molecular_functionHsp70 protein binding
I0030672cellular_componentsynaptic vesicle membrane
I0031092cellular_componentplatelet alpha granule membrane
I0031115biological_processnegative regulation of microtubule polymerization
I0031623biological_processreceptor internalization
I0031648biological_processprotein destabilization
I0032026biological_processresponse to magnesium ion
I0032496biological_processresponse to lipopolysaccharide
I0032991cellular_componentprotein-containing complex
I0033138biological_processpositive regulation of peptidyl-serine phosphorylation
I0034341biological_processresponse to type II interferon
I0034599biological_processcellular response to oxidative stress
I0035493biological_processSNARE complex assembly
I0035543biological_processpositive regulation of SNARE complex assembly
I0040012biological_processregulation of locomotion
I0042393molecular_functionhistone binding
I0042416biological_processdopamine biosynthetic process
I0042417biological_processdopamine metabolic process
I0042775biological_processmitochondrial ATP synthesis coupled electron transport
I0042802molecular_functionidentical protein binding
I0042995cellular_componentcell projection
I0043014molecular_functionalpha-tubulin binding
I0043025cellular_componentneuronal cell body
I0043027molecular_functioncysteine-type endopeptidase inhibitor activity involved in apoptotic process
I0043030biological_processregulation of macrophage activation
I0043066biological_processnegative regulation of apoptotic process
I0043524biological_processnegative regulation of neuron apoptotic process
I0043679cellular_componentaxon terminus
I0045202cellular_componentsynapse
I0045807biological_processpositive regulation of endocytosis
I0045920biological_processnegative regulation of exocytosis
I0045921biological_processpositive regulation of exocytosis
I0046872molecular_functionmetal ion binding
I0046928biological_processregulation of neurotransmitter secretion
I0048156molecular_functiontau protein binding
I0048168biological_processregulation of neuronal synaptic plasticity
I0048169biological_processregulation of long-term neuronal synaptic plasticity
I0048471cellular_componentperinuclear region of cytoplasm
I0048488biological_processsynaptic vesicle endocytosis
I0048489biological_processsynaptic vesicle transport
I0050544molecular_functionarachidonate binding
I0050729biological_processpositive regulation of inflammatory response
I0050806biological_processpositive regulation of synaptic transmission
I0050808biological_processsynapse organization
I0050812biological_processregulation of acyl-CoA biosynthetic process
I0051219molecular_functionphosphoprotein binding
I0051259biological_processprotein complex oligomerization
I0051262biological_processprotein tetramerization
I0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
I0051402biological_processneuron apoptotic process
I0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
I0051612biological_processnegative regulation of serotonin uptake
I0051621biological_processregulation of norepinephrine uptake
I0051622biological_processnegative regulation of norepinephrine uptake
I0060079biological_processexcitatory postsynaptic potential
I0060291biological_processlong-term synaptic potentiation
I0060732biological_processpositive regulation of inositol phosphate biosynthetic process
I0061024biological_processmembrane organization
I0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
I0070555biological_processresponse to interleukin-1
I0070840molecular_functiondynein complex binding
I0071280biological_processcellular response to copper ion
I0098794cellular_componentpostsynapse
I0099512cellular_componentsupramolecular fiber
I1903136molecular_functioncuprous ion binding
I1903285biological_processpositive regulation of hydrogen peroxide catabolic process
I1904377biological_processpositive regulation of protein localization to cell periphery
I1904715biological_processnegative regulation of chaperone-mediated autophagy
I1905606biological_processregulation of presynapse assembly
I2000377biological_processregulation of reactive oxygen species metabolic process
J0000149molecular_functionSNARE binding
J0000287molecular_functionmagnesium ion binding
J0001774biological_processmicroglial cell activation
J0001921biological_processpositive regulation of receptor recycling
J0001956biological_processpositive regulation of neurotransmitter secretion
J0001963biological_processsynaptic transmission, dopaminergic
J0003779molecular_functionactin binding
J0005507molecular_functioncopper ion binding
J0005509molecular_functioncalcium ion binding
J0005515molecular_functionprotein binding
J0005543molecular_functionphospholipid binding
J0005576cellular_componentextracellular region
J0005615cellular_componentextracellular space
J0005634cellular_componentnucleus
J0005737cellular_componentcytoplasm
J0005739cellular_componentmitochondrion
J0005829cellular_componentcytosol
J0005856cellular_componentcytoskeleton
J0005886cellular_componentplasma membrane
J0005938cellular_componentcell cortex
J0006631biological_processfatty acid metabolic process
J0006638biological_processneutral lipid metabolic process
J0006644biological_processphospholipid metabolic process
J0007006biological_processmitochondrial membrane organization
J0007268biological_processchemical synaptic transmission
J0007269biological_processneurotransmitter secretion
J0008198molecular_functionferrous iron binding
J0008270molecular_functionzinc ion binding
J0008289molecular_functionlipid binding
J0008344biological_processadult locomotory behavior
J0009410biological_processresponse to xenobiotic stimulus
J0010040biological_processresponse to iron(II) ion
J0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
J0014048biological_processregulation of glutamate secretion
J0014059biological_processregulation of dopamine secretion
J0015629cellular_componentactin cytoskeleton
J0016020cellular_componentmembrane
J0016079biological_processsynaptic vesicle exocytosis
J0016082biological_processsynaptic vesicle priming
J0016234cellular_componentinclusion body
J0016491molecular_functionoxidoreductase activity
J0019894molecular_functionkinesin binding
J0030424cellular_componentaxon
J0030426cellular_componentgrowth cone
J0030544molecular_functionHsp70 protein binding
J0030672cellular_componentsynaptic vesicle membrane
J0031092cellular_componentplatelet alpha granule membrane
J0031115biological_processnegative regulation of microtubule polymerization
J0031623biological_processreceptor internalization
J0031648biological_processprotein destabilization
J0032026biological_processresponse to magnesium ion
J0032496biological_processresponse to lipopolysaccharide
J0032991cellular_componentprotein-containing complex
J0033138biological_processpositive regulation of peptidyl-serine phosphorylation
J0034341biological_processresponse to type II interferon
J0034599biological_processcellular response to oxidative stress
J0035493biological_processSNARE complex assembly
J0035543biological_processpositive regulation of SNARE complex assembly
J0040012biological_processregulation of locomotion
J0042393molecular_functionhistone binding
J0042416biological_processdopamine biosynthetic process
J0042417biological_processdopamine metabolic process
J0042775biological_processmitochondrial ATP synthesis coupled electron transport
J0042802molecular_functionidentical protein binding
J0042995cellular_componentcell projection
J0043014molecular_functionalpha-tubulin binding
J0043025cellular_componentneuronal cell body
J0043027molecular_functioncysteine-type endopeptidase inhibitor activity involved in apoptotic process
J0043030biological_processregulation of macrophage activation
J0043066biological_processnegative regulation of apoptotic process
J0043524biological_processnegative regulation of neuron apoptotic process
J0043679cellular_componentaxon terminus
J0045202cellular_componentsynapse
J0045807biological_processpositive regulation of endocytosis
J0045920biological_processnegative regulation of exocytosis
J0045921biological_processpositive regulation of exocytosis
J0046872molecular_functionmetal ion binding
J0046928biological_processregulation of neurotransmitter secretion
J0048156molecular_functiontau protein binding
J0048168biological_processregulation of neuronal synaptic plasticity
J0048169biological_processregulation of long-term neuronal synaptic plasticity
J0048471cellular_componentperinuclear region of cytoplasm
J0048488biological_processsynaptic vesicle endocytosis
J0048489biological_processsynaptic vesicle transport
J0050544molecular_functionarachidonate binding
J0050729biological_processpositive regulation of inflammatory response
J0050806biological_processpositive regulation of synaptic transmission
J0050808biological_processsynapse organization
J0050812biological_processregulation of acyl-CoA biosynthetic process
J0051219molecular_functionphosphoprotein binding
J0051259biological_processprotein complex oligomerization
J0051262biological_processprotein tetramerization
J0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
J0051402biological_processneuron apoptotic process
J0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
J0051612biological_processnegative regulation of serotonin uptake
J0051621biological_processregulation of norepinephrine uptake
J0051622biological_processnegative regulation of norepinephrine uptake
J0060079biological_processexcitatory postsynaptic potential
J0060291biological_processlong-term synaptic potentiation
J0060732biological_processpositive regulation of inositol phosphate biosynthetic process
J0061024biological_processmembrane organization
J0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
J0070555biological_processresponse to interleukin-1
J0070840molecular_functiondynein complex binding
J0071280biological_processcellular response to copper ion
J0098794cellular_componentpostsynapse
J0099512cellular_componentsupramolecular fiber
J1903136molecular_functioncuprous ion binding
J1903285biological_processpositive regulation of hydrogen peroxide catabolic process
J1904377biological_processpositive regulation of protein localization to cell periphery
J1904715biological_processnegative regulation of chaperone-mediated autophagy
J1905606biological_processregulation of presynapse assembly
J2000377biological_processregulation of reactive oxygen species metabolic process
K0000149molecular_functionSNARE binding
K0000287molecular_functionmagnesium ion binding
K0001774biological_processmicroglial cell activation
K0001921biological_processpositive regulation of receptor recycling
K0001956biological_processpositive regulation of neurotransmitter secretion
K0001963biological_processsynaptic transmission, dopaminergic
K0003779molecular_functionactin binding
K0005507molecular_functioncopper ion binding
K0005509molecular_functioncalcium ion binding
K0005515molecular_functionprotein binding
K0005543molecular_functionphospholipid binding
K0005576cellular_componentextracellular region
K0005615cellular_componentextracellular space
K0005634cellular_componentnucleus
K0005737cellular_componentcytoplasm
K0005739cellular_componentmitochondrion
K0005829cellular_componentcytosol
K0005856cellular_componentcytoskeleton
K0005886cellular_componentplasma membrane
K0005938cellular_componentcell cortex
K0006631biological_processfatty acid metabolic process
K0006638biological_processneutral lipid metabolic process
K0006644biological_processphospholipid metabolic process
K0007006biological_processmitochondrial membrane organization
K0007268biological_processchemical synaptic transmission
K0007269biological_processneurotransmitter secretion
K0008198molecular_functionferrous iron binding
K0008270molecular_functionzinc ion binding
K0008289molecular_functionlipid binding
K0008344biological_processadult locomotory behavior
K0009410biological_processresponse to xenobiotic stimulus
K0010040biological_processresponse to iron(II) ion
K0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
K0014048biological_processregulation of glutamate secretion
K0014059biological_processregulation of dopamine secretion
K0015629cellular_componentactin cytoskeleton
K0016020cellular_componentmembrane
K0016079biological_processsynaptic vesicle exocytosis
K0016082biological_processsynaptic vesicle priming
K0016234cellular_componentinclusion body
K0016491molecular_functionoxidoreductase activity
K0019894molecular_functionkinesin binding
K0030424cellular_componentaxon
K0030426cellular_componentgrowth cone
K0030544molecular_functionHsp70 protein binding
K0030672cellular_componentsynaptic vesicle membrane
K0031092cellular_componentplatelet alpha granule membrane
K0031115biological_processnegative regulation of microtubule polymerization
K0031623biological_processreceptor internalization
K0031648biological_processprotein destabilization
K0032026biological_processresponse to magnesium ion
K0032496biological_processresponse to lipopolysaccharide
K0032991cellular_componentprotein-containing complex
K0033138biological_processpositive regulation of peptidyl-serine phosphorylation
K0034341biological_processresponse to type II interferon
K0034599biological_processcellular response to oxidative stress
K0035493biological_processSNARE complex assembly
K0035543biological_processpositive regulation of SNARE complex assembly
K0040012biological_processregulation of locomotion
K0042393molecular_functionhistone binding
K0042416biological_processdopamine biosynthetic process
K0042417biological_processdopamine metabolic process
K0042775biological_processmitochondrial ATP synthesis coupled electron transport
K0042802molecular_functionidentical protein binding
K0042995cellular_componentcell projection
K0043014molecular_functionalpha-tubulin binding
K0043025cellular_componentneuronal cell body
K0043027molecular_functioncysteine-type endopeptidase inhibitor activity involved in apoptotic process
K0043030biological_processregulation of macrophage activation
K0043066biological_processnegative regulation of apoptotic process
K0043524biological_processnegative regulation of neuron apoptotic process
K0043679cellular_componentaxon terminus
K0045202cellular_componentsynapse
K0045807biological_processpositive regulation of endocytosis
K0045920biological_processnegative regulation of exocytosis
K0045921biological_processpositive regulation of exocytosis
K0046872molecular_functionmetal ion binding
K0046928biological_processregulation of neurotransmitter secretion
K0048156molecular_functiontau protein binding
K0048168biological_processregulation of neuronal synaptic plasticity
K0048169biological_processregulation of long-term neuronal synaptic plasticity
K0048471cellular_componentperinuclear region of cytoplasm
K0048488biological_processsynaptic vesicle endocytosis
K0048489biological_processsynaptic vesicle transport
K0050544molecular_functionarachidonate binding
K0050729biological_processpositive regulation of inflammatory response
K0050806biological_processpositive regulation of synaptic transmission
K0050808biological_processsynapse organization
K0050812biological_processregulation of acyl-CoA biosynthetic process
K0051219molecular_functionphosphoprotein binding
K0051259biological_processprotein complex oligomerization
K0051262biological_processprotein tetramerization
K0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
K0051402biological_processneuron apoptotic process
K0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
K0051612biological_processnegative regulation of serotonin uptake
K0051621biological_processregulation of norepinephrine uptake
K0051622biological_processnegative regulation of norepinephrine uptake
K0060079biological_processexcitatory postsynaptic potential
K0060291biological_processlong-term synaptic potentiation
K0060732biological_processpositive regulation of inositol phosphate biosynthetic process
K0061024biological_processmembrane organization
K0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
K0070555biological_processresponse to interleukin-1
K0070840molecular_functiondynein complex binding
K0071280biological_processcellular response to copper ion
K0098794cellular_componentpostsynapse
K0099512cellular_componentsupramolecular fiber
K1903136molecular_functioncuprous ion binding
K1903285biological_processpositive regulation of hydrogen peroxide catabolic process
K1904377biological_processpositive regulation of protein localization to cell periphery
K1904715biological_processnegative regulation of chaperone-mediated autophagy
K1905606biological_processregulation of presynapse assembly
K2000377biological_processregulation of reactive oxygen species metabolic process
L0000149molecular_functionSNARE binding
L0000287molecular_functionmagnesium ion binding
L0001774biological_processmicroglial cell activation
L0001921biological_processpositive regulation of receptor recycling
L0001956biological_processpositive regulation of neurotransmitter secretion
L0001963biological_processsynaptic transmission, dopaminergic
L0003779molecular_functionactin binding
L0005507molecular_functioncopper ion binding
L0005509molecular_functioncalcium ion binding
L0005515molecular_functionprotein binding
L0005543molecular_functionphospholipid binding
L0005576cellular_componentextracellular region
L0005615cellular_componentextracellular space
L0005634cellular_componentnucleus
L0005737cellular_componentcytoplasm
L0005739cellular_componentmitochondrion
L0005829cellular_componentcytosol
L0005856cellular_componentcytoskeleton
L0005886cellular_componentplasma membrane
L0005938cellular_componentcell cortex
L0006631biological_processfatty acid metabolic process
L0006638biological_processneutral lipid metabolic process
L0006644biological_processphospholipid metabolic process
L0007006biological_processmitochondrial membrane organization
L0007268biological_processchemical synaptic transmission
L0007269biological_processneurotransmitter secretion
L0008198molecular_functionferrous iron binding
L0008270molecular_functionzinc ion binding
L0008289molecular_functionlipid binding
L0008344biological_processadult locomotory behavior
L0009410biological_processresponse to xenobiotic stimulus
L0010040biological_processresponse to iron(II) ion
L0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
L0014048biological_processregulation of glutamate secretion
L0014059biological_processregulation of dopamine secretion
L0015629cellular_componentactin cytoskeleton
L0016020cellular_componentmembrane
L0016079biological_processsynaptic vesicle exocytosis
L0016082biological_processsynaptic vesicle priming
L0016234cellular_componentinclusion body
L0016491molecular_functionoxidoreductase activity
L0019894molecular_functionkinesin binding
L0030424cellular_componentaxon
L0030426cellular_componentgrowth cone
L0030544molecular_functionHsp70 protein binding
L0030672cellular_componentsynaptic vesicle membrane
L0031092cellular_componentplatelet alpha granule membrane
L0031115biological_processnegative regulation of microtubule polymerization
L0031623biological_processreceptor internalization
L0031648biological_processprotein destabilization
L0032026biological_processresponse to magnesium ion
L0032496biological_processresponse to lipopolysaccharide
L0032991cellular_componentprotein-containing complex
L0033138biological_processpositive regulation of peptidyl-serine phosphorylation
L0034341biological_processresponse to type II interferon
L0034599biological_processcellular response to oxidative stress
L0035493biological_processSNARE complex assembly
L0035543biological_processpositive regulation of SNARE complex assembly
L0040012biological_processregulation of locomotion
L0042393molecular_functionhistone binding
L0042416biological_processdopamine biosynthetic process
L0042417biological_processdopamine metabolic process
L0042775biological_processmitochondrial ATP synthesis coupled electron transport
L0042802molecular_functionidentical protein binding
L0042995cellular_componentcell projection
L0043014molecular_functionalpha-tubulin binding
L0043025cellular_componentneuronal cell body
L0043027molecular_functioncysteine-type endopeptidase inhibitor activity involved in apoptotic process
L0043030biological_processregulation of macrophage activation
L0043066biological_processnegative regulation of apoptotic process
L0043524biological_processnegative regulation of neuron apoptotic process
L0043679cellular_componentaxon terminus
L0045202cellular_componentsynapse
L0045807biological_processpositive regulation of endocytosis
L0045920biological_processnegative regulation of exocytosis
L0045921biological_processpositive regulation of exocytosis
L0046872molecular_functionmetal ion binding
L0046928biological_processregulation of neurotransmitter secretion
L0048156molecular_functiontau protein binding
L0048168biological_processregulation of neuronal synaptic plasticity
L0048169biological_processregulation of long-term neuronal synaptic plasticity
L0048471cellular_componentperinuclear region of cytoplasm
L0048488biological_processsynaptic vesicle endocytosis
L0048489biological_processsynaptic vesicle transport
L0050544molecular_functionarachidonate binding
L0050729biological_processpositive regulation of inflammatory response
L0050806biological_processpositive regulation of synaptic transmission
L0050808biological_processsynapse organization
L0050812biological_processregulation of acyl-CoA biosynthetic process
L0051219molecular_functionphosphoprotein binding
L0051259biological_processprotein complex oligomerization
L0051262biological_processprotein tetramerization
L0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
L0051402biological_processneuron apoptotic process
L0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
L0051612biological_processnegative regulation of serotonin uptake
L0051621biological_processregulation of norepinephrine uptake
L0051622biological_processnegative regulation of norepinephrine uptake
L0060079biological_processexcitatory postsynaptic potential
L0060291biological_processlong-term synaptic potentiation
L0060732biological_processpositive regulation of inositol phosphate biosynthetic process
L0061024biological_processmembrane organization
L0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
L0070555biological_processresponse to interleukin-1
L0070840molecular_functiondynein complex binding
L0071280biological_processcellular response to copper ion
L0098794cellular_componentpostsynapse
L0099512cellular_componentsupramolecular fiber
L1903136molecular_functioncuprous ion binding
L1903285biological_processpositive regulation of hydrogen peroxide catabolic process
L1904377biological_processpositive regulation of protein localization to cell periphery
L1904715biological_processnegative regulation of chaperone-mediated autophagy
L1905606biological_processregulation of presynapse assembly
L2000377biological_processregulation of reactive oxygen species metabolic process
M0000149molecular_functionSNARE binding
M0000287molecular_functionmagnesium ion binding
M0001774biological_processmicroglial cell activation
M0001921biological_processpositive regulation of receptor recycling
M0001956biological_processpositive regulation of neurotransmitter secretion
M0001963biological_processsynaptic transmission, dopaminergic
M0003779molecular_functionactin binding
M0005507molecular_functioncopper ion binding
M0005509molecular_functioncalcium ion binding
M0005515molecular_functionprotein binding
M0005543molecular_functionphospholipid binding
M0005576cellular_componentextracellular region
M0005615cellular_componentextracellular space
M0005634cellular_componentnucleus
M0005737cellular_componentcytoplasm
M0005739cellular_componentmitochondrion
M0005829cellular_componentcytosol
M0005856cellular_componentcytoskeleton
M0005886cellular_componentplasma membrane
M0005938cellular_componentcell cortex
M0006631biological_processfatty acid metabolic process
M0006638biological_processneutral lipid metabolic process
M0006644biological_processphospholipid metabolic process
M0007006biological_processmitochondrial membrane organization
M0007268biological_processchemical synaptic transmission
M0007269biological_processneurotransmitter secretion
M0008198molecular_functionferrous iron binding
M0008270molecular_functionzinc ion binding
M0008289molecular_functionlipid binding
M0008344biological_processadult locomotory behavior
M0009410biological_processresponse to xenobiotic stimulus
M0010040biological_processresponse to iron(II) ion
M0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
M0014048biological_processregulation of glutamate secretion
M0014059biological_processregulation of dopamine secretion
M0015629cellular_componentactin cytoskeleton
M0016020cellular_componentmembrane
M0016079biological_processsynaptic vesicle exocytosis
M0016082biological_processsynaptic vesicle priming
M0016234cellular_componentinclusion body
M0016491molecular_functionoxidoreductase activity
M0019894molecular_functionkinesin binding
M0030424cellular_componentaxon
M0030426cellular_componentgrowth cone
M0030544molecular_functionHsp70 protein binding
M0030672cellular_componentsynaptic vesicle membrane
M0031092cellular_componentplatelet alpha granule membrane
M0031115biological_processnegative regulation of microtubule polymerization
M0031623biological_processreceptor internalization
M0031648biological_processprotein destabilization
M0032026biological_processresponse to magnesium ion
M0032496biological_processresponse to lipopolysaccharide
M0032991cellular_componentprotein-containing complex
M0033138biological_processpositive regulation of peptidyl-serine phosphorylation
M0034341biological_processresponse to type II interferon
M0034599biological_processcellular response to oxidative stress
M0035493biological_processSNARE complex assembly
M0035543biological_processpositive regulation of SNARE complex assembly
M0040012biological_processregulation of locomotion
M0042393molecular_functionhistone binding
M0042416biological_processdopamine biosynthetic process
M0042417biological_processdopamine metabolic process
M0042775biological_processmitochondrial ATP synthesis coupled electron transport
M0042802molecular_functionidentical protein binding
M0042995cellular_componentcell projection
M0043014molecular_functionalpha-tubulin binding
M0043025cellular_componentneuronal cell body
M0043027molecular_functioncysteine-type endopeptidase inhibitor activity involved in apoptotic process
M0043030biological_processregulation of macrophage activation
M0043066biological_processnegative regulation of apoptotic process
M0043524biological_processnegative regulation of neuron apoptotic process
M0043679cellular_componentaxon terminus
M0045202cellular_componentsynapse
M0045807biological_processpositive regulation of endocytosis
M0045920biological_processnegative regulation of exocytosis
M0045921biological_processpositive regulation of exocytosis
M0046872molecular_functionmetal ion binding
M0046928biological_processregulation of neurotransmitter secretion
M0048156molecular_functiontau protein binding
M0048168biological_processregulation of neuronal synaptic plasticity
M0048169biological_processregulation of long-term neuronal synaptic plasticity
M0048471cellular_componentperinuclear region of cytoplasm
M0048488biological_processsynaptic vesicle endocytosis
M0048489biological_processsynaptic vesicle transport
M0050544molecular_functionarachidonate binding
M0050729biological_processpositive regulation of inflammatory response
M0050806biological_processpositive regulation of synaptic transmission
M0050808biological_processsynapse organization
M0050812biological_processregulation of acyl-CoA biosynthetic process
M0051219molecular_functionphosphoprotein binding
M0051259biological_processprotein complex oligomerization
M0051262biological_processprotein tetramerization
M0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
M0051402biological_processneuron apoptotic process
M0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
M0051612biological_processnegative regulation of serotonin uptake
M0051621biological_processregulation of norepinephrine uptake
M0051622biological_processnegative regulation of norepinephrine uptake
M0060079biological_processexcitatory postsynaptic potential
M0060291biological_processlong-term synaptic potentiation
M0060732biological_processpositive regulation of inositol phosphate biosynthetic process
M0061024biological_processmembrane organization
M0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
M0070555biological_processresponse to interleukin-1
M0070840molecular_functiondynein complex binding
M0071280biological_processcellular response to copper ion
M0098794cellular_componentpostsynapse
M0099512cellular_componentsupramolecular fiber
M1903136molecular_functioncuprous ion binding
M1903285biological_processpositive regulation of hydrogen peroxide catabolic process
M1904377biological_processpositive regulation of protein localization to cell periphery
M1904715biological_processnegative regulation of chaperone-mediated autophagy
M1905606biological_processregulation of presynapse assembly
M2000377biological_processregulation of reactive oxygen species metabolic process
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues24
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
AASP2
FHIS50
GASP2
GHIS50
HASP2
HHIS50
IASP2
IHIS50
JASP2
JHIS50
KASP2
AHIS50
KHIS50
LASP2
LHIS50
MASP2
MHIS50
BASP2
BHIS50
DASP2
DHIS50
EASP2
EHIS50
FASP2

site_idSWS_FT_FI2
Number of Residues12
DetailsMOD_RES: N-acetylmethionine => ECO:0000250|UniProtKB:P37840
ChainResidueDetails
AMET1
KMET1
LMET1
MMET1
BMET1
DMET1
EMET1
FMET1
GMET1
HMET1
IMET1
JMET1

site_idSWS_FT_FI3
Number of Residues12
DetailsMOD_RES: Phosphotyrosine; by FYN => ECO:0000250|UniProtKB:P37840
ChainResidueDetails
ATYR125
KTYR125
LTYR125
MTYR125
BTYR125
DTYR125
ETYR125
FTYR125
GTYR125
HTYR125
ITYR125
JTYR125

site_idSWS_FT_FI4
Number of Residues12
DetailsMOD_RES: Phosphoserine; by PLK2 => ECO:0000269|PubMed:19004816
ChainResidueDetails
ASER129
KSER129
LSER129
MSER129
BSER129
DSER129
ESER129
FSER129
GSER129
HSER129
ISER129
JSER129

227344

PDB entries from 2024-11-13

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