8UIC
Structure of the Drosophila IntS11-CG7044(dBRAT1) complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| K | 0000822 | molecular_function | inositol hexakisphosphate binding |
| K | 0004521 | molecular_function | RNA endonuclease activity |
| K | 0005515 | molecular_function | protein binding |
| K | 0005634 | cellular_component | nucleus |
| K | 0005737 | cellular_component | cytoplasm |
| K | 0005829 | cellular_component | cytosol |
| K | 0016180 | biological_process | snRNA processing |
| K | 0016787 | molecular_function | hydrolase activity |
| K | 0031123 | biological_process | RNA 3'-end processing |
| K | 0032039 | cellular_component | integrator complex |
| K | 0034472 | biological_process | snRNA 3'-end processing |
| K | 0046872 | molecular_function | metal ion binding |
| K | 0160232 | cellular_component | INTAC complex |
| K | 0160240 | biological_process | RNA polymerase II transcription initiation surveillance |
| T | 0005634 | cellular_component | nucleus |
| T | 0005829 | cellular_component | cytosol |
| T | 0006974 | biological_process | DNA damage response |
| T | 0008283 | biological_process | cell population proliferation |
| T | 0046872 | molecular_function | metal ion binding |
| T | 0160234 | biological_process | integrator complex assembly |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 5 |
| Details | Motif: {"description":"HXHXDH motif"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"31530651","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"31809743","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"36180473","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"39032490","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7SN8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UIC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Motif: {"description":"BRAT1-like motif","evidences":[{"source":"PubMed","id":"39032490","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"39032490","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8UIC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |






