8UGL
High resolution in-situ structure of complex IV in respiratory supercomplex
This is a non-PDB format compatible entry.
Functional Information from PROSITE/UniProt
| site_id | PS00077 |
| Number of Residues | 56 |
| Details | COX1_CUB Heme-copper oxidase catalytic subunit, copper B binding region signature. WFFGHPeVyililpgfgmishivtyysgkkepfgymgmvwammsigflgfivwa.HH |
| Chain | Residue | Details |
| 4A | TRP236-HIS291 |
| site_id | PS00078 |
| Number of Residues | 49 |
| Details | COX2 CO II and nitrous oxide reductase dinuclear copper centers signature. VlHswavpslglktdaipgrlnqttlmstrpglyygq......CseiCgsnHsfM |
| Chain | Residue | Details |
| 4B | VAL159-MET207 |
| site_id | PS00848 |
| Number of Residues | 23 |
| Details | COX5B_1 Cytochrome c oxidase subunit Vb, zinc binding region signature. VIWfwvhkgetqrCpsCGthYKL |
| Chain | Residue | Details |
| 4F | VAL69-LEU91 |
| site_id | PS01329 |
| Number of Residues | 18 |
| Details | COX6A Cytochrome c oxidase subunit VIa signature. IRtKpYsWGDGnHTlFhN |
| Chain | Residue | Details |
| 4G | ILE55-ASN72 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | TOPO_DOM: Mitochondrial matrix => ECO:0000250|UniProtKB:P00430 |
| Chain | Residue | Details |
| 4L | SER1-ASN17 | |
| 4F | CYS62 | |
| 4F | CYS82 | |
| 4F | CYS85 | |
| 4A | HIS328-SER335 | |
| 4A | SER401-ASN406 | |
| 4A | LYS479-LYS514 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 26 |
| Details | TRANSMEM: Helical => ECO:0000250|UniProtKB:P00430 |
| Chain | Residue | Details |
| 4L | LYS18-LEU44 | |
| 4F | LYS55 | |
| 4F | LYS90 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | TOPO_DOM: Mitochondrial intermembrane => ECO:0000250|UniProtKB:P00430 |
| Chain | Residue | Details |
| 4L | LEU45-LYS47 | |
| 4C | LEU106-GLU128 | |
| 4C | ALA184-ASP190 | |
| 4C | TYR257-SER261 | |
| 4A | LEU358-THR370 | |
| 4A | SER434-ALA446 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P17665 |
| Chain | Residue | Details |
| 4L | LYS9 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 32 |
| Details | TRANSMEM: Helical; Name=III => ECO:0000250|UniProtKB:P00415 |
| Chain | Residue | Details |
| 4C | SER73-SER105 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 23 |
| Details | TRANSMEM: Helical; Name=IV => ECO:0000250|UniProtKB:P00415 |
| Chain | Residue | Details |
| 4C | VAL129-MET152 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 27 |
| Details | TRANSMEM: Helical; Name=V => ECO:0000250|UniProtKB:P00415 |
| Chain | Residue | Details |
| 4C | ARG156-GLU183 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 32 |
| Details | TRANSMEM: Helical; Name=VI => ECO:0000250|UniProtKB:P00415 |
| Chain | Residue | Details |
| 4C | GLY191-LEU223 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 23 |
| Details | TRANSMEM: Helical; Name=VII => ECO:0000250|UniProtKB:P00415 |
| Chain | Residue | Details |
| 4C | PHE233-ILE256 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 28 |
| Details | TRANSMEM: Helical; Name=VIII => ECO:0000250|UniProtKB:P00396 |
| Chain | Residue | Details |
| 4A | VAL299-LEU327 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 21 |
| Details | TRANSMEM: Helical; Name=IX => ECO:0000250|UniProtKB:P00396 |
| Chain | Residue | Details |
| 4A | PRO336-VAL357 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 29 |
| Details | TRANSMEM: Helical; Name=X => ECO:0000250|UniProtKB:P00396 |
| Chain | Residue | Details |
| 4A | TYR371-PHE400 |
| site_id | SWS_FT_FI13 |
| Number of Residues | 26 |
| Details | TRANSMEM: Helical; Name=XI => ECO:0000250|UniProtKB:P00396 |
| Chain | Residue | Details |
| 4A | GLN407-LEU433 |
| site_id | SWS_FT_FI14 |
| Number of Residues | 31 |
| Details | TRANSMEM: Helical; Name=XII => ECO:0000250|UniProtKB:P00396 |
| Chain | Residue | Details |
| 4A | TYR447-SER478 |
| site_id | SWS_FT_FI15 |
| Number of Residues | 9 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:P00396 |
| Chain | Residue | Details |
| 4A | GLU40 | |
| 4A | GLY45 | |
| 4A | HIS240 | |
| 4A | TYR244 | |
| 4A | HIS290 | |
| 4A | HIS291 | |
| 4A | HIS368 | |
| 4A | ASP369 | |
| 4A | SER441 |
| site_id | SWS_FT_FI16 |
| Number of Residues | 3 |
| Details | BINDING: axial binding residue => ECO:0000250|UniProtKB:P00396 |
| Chain | Residue | Details |
| 4A | HIS61 | |
| 4A | HIS376 | |
| 4A | HIS378 |
| site_id | SWS_FT_FI17 |
| Number of Residues | 2 |
| Details | CROSSLNK: 1'-histidyl-3'-tyrosine (His-Tyr) => ECO:0000250|UniProtKB:P00396 |
| Chain | Residue | Details |
| 4A | HIS240 | |
| 4A | TYR244 |
