8UEC
Structure of TREK-1CG*:CAT335a
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005267 | molecular_function | potassium channel activity |
| A | 0016020 | cellular_component | membrane |
| A | 0071805 | biological_process | potassium ion transmembrane transport |
| B | 0005267 | molecular_function | potassium channel activity |
| B | 0016020 | cellular_component | membrane |
| B | 0071805 | biological_process | potassium ion transmembrane transport |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 160 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| A | ALA62-ILE82 | |
| A | PHE172-VAL192 | |
| A | VAL223-TYR243 | |
| A | VAL288-GLY308 | |
| B | ALA62-ILE82 | |
| B | PHE172-VAL192 | |
| B | VAL223-TYR243 | |
| B | VAL288-GLY308 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 52 |
| Details | INTRAMEM: Pore-forming; Name=Pore-forming 1 => ECO:0000255 |
| Chain | Residue | Details |
| A | GLY144-PHE170 | |
| B | GLY144-PHE170 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 58 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| A | GLU193-PHE222 | |
| B | GLU193-PHE222 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 60 |
| Details | INTRAMEM: Pore-forming; Name=Pore-forming 2 => ECO:0000255 |
| Chain | Residue | Details |
| A | GLY253-ALA283 | |
| B | GLY253-ALA283 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:28693035, ECO:0000269|PubMed:33127683, ECO:0007744|PDB:6W7B, ECO:0007744|PDB:6W83 |
| Chain | Residue | Details |
| A | ILE157 | |
| B | ILE157 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:33127683, ECO:0007744|PDB:6W83 |
| Chain | Residue | Details |
| A | PHE158 | |
| B | LEU267 | |
| B | ASP268 | |
| B | PHE269 | |
| A | CYS159 | |
| A | ILE160 | |
| A | LEU267 | |
| A | ASP268 | |
| A | PHE269 | |
| B | PHE158 | |
| B | CYS159 | |
| B | ILE160 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:28693035, ECO:0007744|PDB:6W7B, ECO:0007744|PDB:6W83 |
| Chain | Residue | Details |
| A | TYR266 | |
| B | TYR266 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | SITE: pH sensor => ECO:0000269|PubMed:19667202, ECO:0000269|PubMed:27035963 |
| Chain | Residue | Details |
| A | THR141 | |
| B | THR141 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ILE110 | |
| A | PHE134 | |
| B | ILE110 | |
| B | PHE134 |
