Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

8UBY

Choline-bound FLVCR1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005739	cellular_component	mitochondrion
A	0005743	cellular_component	mitochondrial inner membrane
A	0005886	cellular_component	plasma membrane
A	0006783	biological_process	heme biosynthetic process
A	0006839	biological_process	mitochondrial transport
A	0006879	biological_process	intracellular iron ion homeostasis
A	0008654	biological_process	phospholipid biosynthetic process
A	0015220	molecular_function	choline transmembrane transporter activity
A	0015232	molecular_function	heme transmembrane transporter activity
A	0015871	biological_process	choline transport
A	0015886	biological_process	heme transport
A	0016020	cellular_component	membrane
A	0020037	molecular_function	heme binding
A	0022857	molecular_function	transmembrane transporter activity
A	0030218	biological_process	erythrocyte differentiation
A	0031966	cellular_component	mitochondrial membrane
A	0034228	molecular_function	ethanolamine transmembrane transporter activity
A	0034229	biological_process	ethanolamine transport
A	0043249	biological_process	erythrocyte maturation
A	0055085	biological_process	transmembrane transport
A	0097037	biological_process	heme export

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	Transmembrane: {"description":"Helical; Name=TM1","evidences":[{"source":"PubMed","id":"38693265","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38778100","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8QCS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8QCT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8R8T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	34
Details	Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"38693265","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38778100","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8QCS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8QCT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8R8T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	27
Details	Transmembrane: {"description":"Helical; Name=TM2","evidences":[{"source":"PubMed","id":"38693265","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38778100","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8QCS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8QCT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8R8T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	48
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"38693265","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38778100","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8QCS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8QCT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8R8T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	19
Details	Transmembrane: {"description":"Helical; Name=TM3","evidences":[{"source":"PubMed","id":"38693265","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38778100","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8QCS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8QCT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8R8T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	28
Details	Transmembrane: {"description":"Helical; Name=TM4","evidences":[{"source":"PubMed","id":"38693265","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38778100","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8QCS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8QCT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8R8T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	25
Details	Transmembrane: {"description":"Helical; Name=TM5","evidences":[{"source":"PubMed","id":"38693265","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38778100","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8QCS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8QCT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8R8T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	29
Details	Transmembrane: {"description":"Helical; Name=TM6","evidences":[{"source":"PubMed","id":"38693265","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38778100","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8QCS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8QCT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8R8T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	30
Details	Transmembrane: {"description":"Helical; Name=TM7","evidences":[{"source":"PubMed","id":"38693265","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38778100","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8QCS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8QCT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8R8T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	28
Details	Transmembrane: {"description":"Helical; Name=TM8","evidences":[{"source":"PubMed","id":"38693265","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38778100","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8QCS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8QCT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8R8T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI11
Number of Residues	22
Details	Transmembrane: {"description":"Helical; Name=TM9","evidences":[{"source":"PubMed","id":"38693265","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38778100","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8QCS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8QCT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8R8T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI12
Number of Residues	29
Details	Transmembrane: {"description":"Helical; Name=TM10","evidences":[{"source":"PubMed","id":"38693265","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38778100","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8QCS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8QCT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8R8T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI13
Number of Residues	25
Details	Transmembrane: {"description":"Helical; Name=TM11","evidences":[{"source":"PubMed","id":"38693265","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38778100","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8QCS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8QCT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8R8T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI14
Number of Residues	22
Details	Transmembrane: {"description":"Helical; Name=TM12","evidences":[{"source":"PubMed","id":"38693265","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38778100","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8QCS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8QCT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8R8T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI15
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"38693265","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38778100","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8R8T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI16
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"38693265","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8R8T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8UBX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI17
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)