8U8E

Cryo-EM structure of the TREX-2 complex in association with Sub2

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0000282	biological_process	cellular bud site selection
B	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
B	0003690	molecular_function	double-stranded DNA binding
B	0003723	molecular_function	RNA binding
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005635	cellular_component	nuclear envelope
B	0006283	biological_process	transcription-coupled nucleotide-excision repair
B	0006368	biological_process	transcription elongation by RNA polymerase II
B	0006406	biological_process	mRNA export from nucleus
B	0016973	biological_process	poly(A)+ mRNA export from nucleus
B	0031124	biological_process	mRNA 3'-end processing
B	0045944	biological_process	positive regulation of transcription by RNA polymerase II
B	0051028	biological_process	mRNA transport
B	0070390	cellular_component	transcription export complex 2
B	0071028	biological_process	nuclear mRNA surveillance
C	0000502	cellular_component	proteasome complex
C	0000724	biological_process	double-strand break repair via homologous recombination
C	0003674	molecular_function	molecular_function
C	0005515	molecular_function	protein binding
C	0005829	cellular_component	cytosol
C	0006351	biological_process	DNA-templated transcription
C	0006406	biological_process	mRNA export from nucleus
C	0006457	biological_process	protein folding
C	0006511	biological_process	ubiquitin-dependent protein catabolic process
C	0008541	cellular_component	proteasome regulatory particle, lid subcomplex
C	0030447	biological_process	filamentous growth
C	0034515	cellular_component	proteasome storage granule
C	0035753	biological_process	maintenance of DNA trinucleotide repeats
C	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
C	0043248	biological_process	proteasome assembly
C	0044183	molecular_function	protein folding chaperone
C	0045944	biological_process	positive regulation of transcription by RNA polymerase II
C	0051726	biological_process	regulation of cell cycle
C	0060090	molecular_function	molecular adaptor activity
C	0070390	cellular_component	transcription export complex 2
C	0072742	biological_process	SAGA complex localization to transcription regulatory region
D	0000166	molecular_function	nucleotide binding
D	0000346	cellular_component	transcription export complex
D	0000398	biological_process	mRNA splicing, via spliceosome
D	0000781	cellular_component	chromosome, telomeric region
D	0003676	molecular_function	nucleic acid binding
D	0003723	molecular_function	RNA binding
D	0003724	molecular_function	RNA helicase activity
D	0003729	molecular_function	mRNA binding
D	0004386	molecular_function	helicase activity
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005634	cellular_component	nucleus
D	0005681	cellular_component	spliceosomal complex
D	0005737	cellular_component	cytoplasm
D	0006283	biological_process	transcription-coupled nucleotide-excision repair
D	0006368	biological_process	transcription elongation by RNA polymerase II
D	0006397	biological_process	mRNA processing
D	0006406	biological_process	mRNA export from nucleus
D	0008380	biological_process	RNA splicing
D	0010467	biological_process	gene expression
D	0016787	molecular_function	hydrolase activity
D	0016887	molecular_function	ATP hydrolysis activity
D	0031124	biological_process	mRNA 3'-end processing
D	0031509	biological_process	subtelomeric heterochromatin formation
D	0042802	molecular_function	identical protein binding
D	0051028	biological_process	mRNA transport

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	402
Details	Domain: {"description":"PCI","evidences":[{"source":"PROSITE-ProRule","id":"PRU01185","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	3
Details	Motif: {"description":"DECD box"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	7
Details	Binding site: {}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17330950","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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