8U3S
Structure of human TIRR in complex with VHH4 nanobody
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003723 | molecular_function | RNA binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0006402 | biological_process | mRNA catabolic process |
| A | 0016077 | biological_process | sno(s)RNA catabolic process |
| A | 0030515 | molecular_function | snoRNA binding |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0140933 | molecular_function | 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity |
| A | 1990174 | molecular_function | phosphodiesterase decapping endonuclease activity |
| A | 2001033 | biological_process | negative regulation of double-strand break repair via nonhomologous end joining |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 87 |
| Details | Region: {"description":"Interaction with PXN","evidences":[{"source":"UniProtKB","id":"Q8VHN8","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Site: {"description":"Required for interaction with TP53BP1","evidences":[{"source":"PubMed","id":"28241136","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"28241136","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
