8TZS
Structure of human WLS
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000139 | cellular_component | Golgi membrane |
| A | 0001707 | biological_process | mesoderm formation |
| A | 0005515 | molecular_function | protein binding |
| A | 0005769 | cellular_component | early endosome |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0005789 | cellular_component | endoplasmic reticulum membrane |
| A | 0005794 | cellular_component | Golgi apparatus |
| A | 0005802 | cellular_component | trans-Golgi network |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006886 | biological_process | intracellular protein transport |
| A | 0009948 | biological_process | anterior/posterior axis specification |
| A | 0012505 | cellular_component | endomembrane system |
| A | 0016055 | biological_process | Wnt signaling pathway |
| A | 0017147 | molecular_function | Wnt-protein binding |
| A | 0030177 | biological_process | positive regulation of Wnt signaling pathway |
| A | 0030659 | cellular_component | cytoplasmic vesicle membrane |
| A | 0030666 | cellular_component | endocytic vesicle membrane |
| A | 0030901 | biological_process | midbrain development |
| A | 0030902 | biological_process | hindbrain development |
| A | 0031017 | biological_process | exocrine pancreas development |
| A | 0031090 | cellular_component | organelle membrane |
| A | 0031410 | cellular_component | cytoplasmic vesicle |
| A | 0031901 | cellular_component | early endosome membrane |
| A | 0043123 | biological_process | positive regulation of canonical NF-kappaB signal transduction |
| A | 0061355 | biological_process | Wnt protein secretion |
| A | 0061357 | biological_process | positive regulation of Wnt protein secretion |
| A | 0070062 | cellular_component | extracellular exosome |
| A | 0071529 | biological_process | cementum mineralization |
| A | 0090263 | biological_process | positive regulation of canonical Wnt signaling pathway |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=1","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 235 |
| Details | Topological domain: {"description":"Lumenal","evidences":[{"source":"PubMed","id":"20652957","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=2","evidences":[{"source":"PubMed","id":"20652957","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 20 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"20652957","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=3","evidences":[{"source":"PubMed","id":"20652957","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=4","evidences":[{"source":"PubMed","id":"20652957","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=5","evidences":[{"source":"PubMed","id":"20652957","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=6","evidences":[{"source":"PubMed","id":"20652957","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=7","evidences":[{"source":"PubMed","id":"20652957","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=8","evidences":[{"source":"PubMed","id":"20652957","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 131 |
| Details | Region: {"description":"Interaction with Wnt proteins","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
