8TS2

Cryo-EM structure of human MRS2 with EDTA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005506	molecular_function	iron ion binding
A	0009055	molecular_function	electron transfer activity
A	0020037	molecular_function	heme binding
A	0022900	biological_process	electron transport chain
A	0042597	cellular_component	periplasmic space
A	0046872	molecular_function	metal ion binding
B	0005506	molecular_function	iron ion binding
B	0009055	molecular_function	electron transfer activity
B	0020037	molecular_function	heme binding
B	0022900	biological_process	electron transport chain
B	0042597	cellular_component	periplasmic space
B	0046872	molecular_function	metal ion binding
C	0005506	molecular_function	iron ion binding
C	0009055	molecular_function	electron transfer activity
C	0020037	molecular_function	heme binding
C	0022900	biological_process	electron transport chain
C	0042597	cellular_component	periplasmic space
C	0046872	molecular_function	metal ion binding
D	0005506	molecular_function	iron ion binding
D	0009055	molecular_function	electron transfer activity
D	0020037	molecular_function	heme binding
D	0022900	biological_process	electron transport chain
D	0042597	cellular_component	periplasmic space
D	0046872	molecular_function	metal ion binding
E	0005506	molecular_function	iron ion binding
E	0009055	molecular_function	electron transfer activity
E	0020037	molecular_function	heme binding
E	0022900	biological_process	electron transport chain
E	0042597	cellular_component	periplasmic space
E	0046872	molecular_function	metal ion binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	95
Details	Transmembrane: {"description":"Helical; Name=1","evidences":[{"source":"PubMed","id":"37543649","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37938562","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"39609651","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8IP3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8IP4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8IP5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8IP6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8TS1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8TS2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8TS3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8TUL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8TUP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	50
Details	Topological domain: {"description":"Mitochondrial intermembrane","evidences":[{"source":"PubMed","id":"37543649","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37938562","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"39609651","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8IP3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8IP4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8IP5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8IP6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8TS1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8TS2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8TS3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8TUL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8TUP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	10
Details	Motif: {"description":"GMN motif","evidences":[{"source":"PubMed","id":"37543649","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37938562","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"39609651","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	20
Details	Binding site: {"evidences":[{"source":"PubMed","id":"37543649","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37938562","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"39609651","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8IP3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8TS1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8TUL","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PubMed","id":"37543649","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37938562","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"39609651","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8IP3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8IP4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8IP5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8TUL","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PubMed","id":"37543649","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37938562","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"39609651","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8IP3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8IP4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8IP5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8TUL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8TUP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PubMed","id":"37543649","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37938562","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"39609651","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8IP3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8IP4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8IP5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8TS1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8TUP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---