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8TNT

Crystal structure of Epstein-Barr virus gH/gL/gp42 in complex with antibodies F-2-1 and 769C2

Functional Information from GO Data
ChainGOidnamespacecontents
A0005515molecular_functionprotein binding
A0019031cellular_componentviral envelope
A0019064biological_processfusion of virus membrane with host plasma membrane
A0020002cellular_componenthost cell plasma membrane
A0039663biological_processmembrane fusion involved in viral entry into host cell
A0044175cellular_componenthost cell endosome membrane
A0044423cellular_componentvirion component
A0046718biological_processsymbiont entry into host cell
A0055036cellular_componentvirion membrane
B0005515molecular_functionprotein binding
B0019031cellular_componentviral envelope
B0019064biological_processfusion of virus membrane with host plasma membrane
B0020002cellular_componenthost cell plasma membrane
B0039663biological_processmembrane fusion involved in viral entry into host cell
B0044177cellular_componenthost cell Golgi apparatus
B0044423cellular_componentvirion component
B0046718biological_processsymbiont entry into host cell
B0055036cellular_componentvirion membrane
Functional Information from PROSITE/UniProt
site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH
ChainResidueDetails
ETYR201-HIS207
GTYR199-HIS205
DTYR195-HIS201
FTYR196-HIS202

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues64
DetailsRegion: {"description":"Interaction with gL","evidences":[{"source":"HAMAP-Rule","id":"MF_04033","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues5
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine; by host","evidences":[{"source":"HAMAP-Rule","id":"MF_04033","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21149717","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues106
DetailsDomain: {"description":"C-type lectin"}
ChainResidueDetails

246704

PDB entries from 2025-12-24

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