8TKQ

Cryo-EM structure of human full-length RAD52

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000724	biological_process	double-strand break repair via homologous recombination
A	0000730	biological_process	DNA recombinase assembly
A	0003677	molecular_function	DNA binding
A	0003697	molecular_function	single-stranded DNA binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0006281	biological_process	DNA repair
A	0006302	biological_process	double-strand break repair
A	0006310	biological_process	DNA recombination
A	0006312	biological_process	mitotic recombination
A	0006974	biological_process	DNA damage response
A	0010792	biological_process	DNA double-strand break processing involved in repair via single-strand annealing
A	0032991	cellular_component	protein-containing complex
A	0032993	cellular_component	protein-DNA complex
A	0034599	biological_process	cellular response to oxidative stress
A	0042802	molecular_function	identical protein binding
A	0045002	biological_process	double-strand break repair via single-strand annealing
A	2000819	biological_process	regulation of nucleotide-excision repair
B	0000724	biological_process	double-strand break repair via homologous recombination
B	0000730	biological_process	DNA recombinase assembly
B	0003677	molecular_function	DNA binding
B	0003697	molecular_function	single-stranded DNA binding
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0006281	biological_process	DNA repair
B	0006302	biological_process	double-strand break repair
B	0006310	biological_process	DNA recombination
B	0006312	biological_process	mitotic recombination
B	0006974	biological_process	DNA damage response
B	0010792	biological_process	DNA double-strand break processing involved in repair via single-strand annealing
B	0032991	cellular_component	protein-containing complex
B	0032993	cellular_component	protein-DNA complex
B	0034599	biological_process	cellular response to oxidative stress
B	0042802	molecular_function	identical protein binding
B	0045002	biological_process	double-strand break repair via single-strand annealing
B	2000819	biological_process	regulation of nucleotide-excision repair
C	0000724	biological_process	double-strand break repair via homologous recombination
C	0000730	biological_process	DNA recombinase assembly
C	0003677	molecular_function	DNA binding
C	0003697	molecular_function	single-stranded DNA binding
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0006281	biological_process	DNA repair
C	0006302	biological_process	double-strand break repair
C	0006310	biological_process	DNA recombination
C	0006312	biological_process	mitotic recombination
C	0006974	biological_process	DNA damage response
C	0010792	biological_process	DNA double-strand break processing involved in repair via single-strand annealing
C	0032991	cellular_component	protein-containing complex
C	0032993	cellular_component	protein-DNA complex
C	0034599	biological_process	cellular response to oxidative stress
C	0042802	molecular_function	identical protein binding
C	0045002	biological_process	double-strand break repair via single-strand annealing
C	2000819	biological_process	regulation of nucleotide-excision repair
D	0000724	biological_process	double-strand break repair via homologous recombination
D	0000730	biological_process	DNA recombinase assembly
D	0003677	molecular_function	DNA binding
D	0003697	molecular_function	single-stranded DNA binding
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0006281	biological_process	DNA repair
D	0006302	biological_process	double-strand break repair
D	0006310	biological_process	DNA recombination
D	0006312	biological_process	mitotic recombination
D	0006974	biological_process	DNA damage response
D	0010792	biological_process	DNA double-strand break processing involved in repair via single-strand annealing
D	0032991	cellular_component	protein-containing complex
D	0032993	cellular_component	protein-DNA complex
D	0034599	biological_process	cellular response to oxidative stress
D	0042802	molecular_function	identical protein binding
D	0045002	biological_process	double-strand break repair via single-strand annealing
D	2000819	biological_process	regulation of nucleotide-excision repair
E	0000724	biological_process	double-strand break repair via homologous recombination
E	0000730	biological_process	DNA recombinase assembly
E	0003677	molecular_function	DNA binding
E	0003697	molecular_function	single-stranded DNA binding
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0006281	biological_process	DNA repair
E	0006302	biological_process	double-strand break repair
E	0006310	biological_process	DNA recombination
E	0006312	biological_process	mitotic recombination
E	0006974	biological_process	DNA damage response
E	0010792	biological_process	DNA double-strand break processing involved in repair via single-strand annealing
E	0032991	cellular_component	protein-containing complex
E	0032993	cellular_component	protein-DNA complex
E	0034599	biological_process	cellular response to oxidative stress
E	0042802	molecular_function	identical protein binding
E	0045002	biological_process	double-strand break repair via single-strand annealing
E	2000819	biological_process	regulation of nucleotide-excision repair
F	0000724	biological_process	double-strand break repair via homologous recombination
F	0000730	biological_process	DNA recombinase assembly
F	0003677	molecular_function	DNA binding
F	0003697	molecular_function	single-stranded DNA binding
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0006281	biological_process	DNA repair
F	0006302	biological_process	double-strand break repair
F	0006310	biological_process	DNA recombination
F	0006312	biological_process	mitotic recombination
F	0006974	biological_process	DNA damage response
F	0010792	biological_process	DNA double-strand break processing involved in repair via single-strand annealing
F	0032991	cellular_component	protein-containing complex
F	0032993	cellular_component	protein-DNA complex
F	0034599	biological_process	cellular response to oxidative stress
F	0042802	molecular_function	identical protein binding
F	0045002	biological_process	double-strand break repair via single-strand annealing
F	2000819	biological_process	regulation of nucleotide-excision repair
G	0000724	biological_process	double-strand break repair via homologous recombination
G	0000730	biological_process	DNA recombinase assembly
G	0003677	molecular_function	DNA binding
G	0003697	molecular_function	single-stranded DNA binding
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0006281	biological_process	DNA repair
G	0006302	biological_process	double-strand break repair
G	0006310	biological_process	DNA recombination
G	0006312	biological_process	mitotic recombination
G	0006974	biological_process	DNA damage response
G	0010792	biological_process	DNA double-strand break processing involved in repair via single-strand annealing
G	0032991	cellular_component	protein-containing complex
G	0032993	cellular_component	protein-DNA complex
G	0034599	biological_process	cellular response to oxidative stress
G	0042802	molecular_function	identical protein binding
G	0045002	biological_process	double-strand break repair via single-strand annealing
G	2000819	biological_process	regulation of nucleotide-excision repair
H	0000724	biological_process	double-strand break repair via homologous recombination
H	0000730	biological_process	DNA recombinase assembly
H	0003677	molecular_function	DNA binding
H	0003697	molecular_function	single-stranded DNA binding
H	0005515	molecular_function	protein binding
H	0005634	cellular_component	nucleus
H	0005654	cellular_component	nucleoplasm
H	0006281	biological_process	DNA repair
H	0006302	biological_process	double-strand break repair
H	0006310	biological_process	DNA recombination
H	0006312	biological_process	mitotic recombination
H	0006974	biological_process	DNA damage response
H	0010792	biological_process	DNA double-strand break processing involved in repair via single-strand annealing
H	0032991	cellular_component	protein-containing complex
H	0032993	cellular_component	protein-DNA complex
H	0034599	biological_process	cellular response to oxidative stress
H	0042802	molecular_function	identical protein binding
H	0045002	biological_process	double-strand break repair via single-strand annealing
H	2000819	biological_process	regulation of nucleotide-excision repair
I	0000724	biological_process	double-strand break repair via homologous recombination
I	0000730	biological_process	DNA recombinase assembly
I	0003677	molecular_function	DNA binding
I	0003697	molecular_function	single-stranded DNA binding
I	0005515	molecular_function	protein binding
I	0005634	cellular_component	nucleus
I	0005654	cellular_component	nucleoplasm
I	0006281	biological_process	DNA repair
I	0006302	biological_process	double-strand break repair
I	0006310	biological_process	DNA recombination
I	0006312	biological_process	mitotic recombination
I	0006974	biological_process	DNA damage response
I	0010792	biological_process	DNA double-strand break processing involved in repair via single-strand annealing
I	0032991	cellular_component	protein-containing complex
I	0032993	cellular_component	protein-DNA complex
I	0034599	biological_process	cellular response to oxidative stress
I	0042802	molecular_function	identical protein binding
I	0045002	biological_process	double-strand break repair via single-strand annealing
I	2000819	biological_process	regulation of nucleotide-excision repair
J	0000724	biological_process	double-strand break repair via homologous recombination
J	0000730	biological_process	DNA recombinase assembly
J	0003677	molecular_function	DNA binding
J	0003697	molecular_function	single-stranded DNA binding
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005654	cellular_component	nucleoplasm
J	0006281	biological_process	DNA repair
J	0006302	biological_process	double-strand break repair
J	0006310	biological_process	DNA recombination
J	0006312	biological_process	mitotic recombination
J	0006974	biological_process	DNA damage response
J	0010792	biological_process	DNA double-strand break processing involved in repair via single-strand annealing
J	0032991	cellular_component	protein-containing complex
J	0032993	cellular_component	protein-DNA complex
J	0034599	biological_process	cellular response to oxidative stress
J	0042802	molecular_function	identical protein binding
J	0045002	biological_process	double-strand break repair via single-strand annealing
J	2000819	biological_process	regulation of nucleotide-excision repair
K	0000724	biological_process	double-strand break repair via homologous recombination
K	0000730	biological_process	DNA recombinase assembly
K	0003677	molecular_function	DNA binding
K	0003697	molecular_function	single-stranded DNA binding
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0005654	cellular_component	nucleoplasm
K	0006281	biological_process	DNA repair
K	0006302	biological_process	double-strand break repair
K	0006310	biological_process	DNA recombination
K	0006312	biological_process	mitotic recombination
K	0006974	biological_process	DNA damage response
K	0010792	biological_process	DNA double-strand break processing involved in repair via single-strand annealing
K	0032991	cellular_component	protein-containing complex
K	0032993	cellular_component	protein-DNA complex
K	0034599	biological_process	cellular response to oxidative stress
K	0042802	molecular_function	identical protein binding
K	0045002	biological_process	double-strand break repair via single-strand annealing
K	2000819	biological_process	regulation of nucleotide-excision repair

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	44
Details	DNA binding: {}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	11
Details	Modified residue: {"description":"Phosphotyrosine; by ABL1","evidences":[{"source":"PubMed","id":"12379650","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	11
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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