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8TIE

Double nuclear outer ring of Nup84-complexes from the yeast NPC

Functional Information from GO Data
ChainGOidnamespacecontents
a0000055biological_processribosomal large subunit export from nucleus
a0000122biological_processnegative regulation of transcription by RNA polymerase II
a0000781cellular_componentchromosome, telomeric region
a0000973biological_processpost-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
a0005515molecular_functionprotein binding
a0005634cellular_componentnucleus
a0005635cellular_componentnuclear envelope
a0005643cellular_componentnuclear pore
a0006302biological_processdouble-strand break repair
a0006406biological_processmRNA export from nucleus
a0006606biological_processprotein import into nucleus
a0006611biological_processprotein export from nucleus
a0006913biological_processnucleocytoplasmic transport
a0015031biological_processprotein transport
a0016020cellular_componentmembrane
a0017056molecular_functionstructural constituent of nuclear pore
a0031080cellular_componentnuclear pore outer ring
a0031509biological_processsubtelomeric heterochromatin formation
a0031965cellular_componentnuclear membrane
a0031990biological_processmRNA export from nucleus in response to heat stress
a0033036biological_processmacromolecule localization
a0034398biological_processtelomere tethering at nuclear periphery
a0042802molecular_functionidentical protein binding
a0045893biological_processpositive regulation of DNA-templated transcription
a0045944biological_processpositive regulation of transcription by RNA polymerase II
a0051028biological_processmRNA transport
a0051664biological_processnuclear pore localization
a0071705biological_processnitrogen compound transport
b0000055biological_processribosomal large subunit export from nucleus
b0005515molecular_functionprotein binding
b0005634cellular_componentnucleus
b0005635cellular_componentnuclear envelope
b0005643cellular_componentnuclear pore
b0006406biological_processmRNA export from nucleus
b0006606biological_processprotein import into nucleus
b0006913biological_processnucleocytoplasmic transport
b0015031biological_processprotein transport
b0016020cellular_componentmembrane
b0017056molecular_functionstructural constituent of nuclear pore
b0031080cellular_componentnuclear pore outer ring
b0031965cellular_componentnuclear membrane
b0045893biological_processpositive regulation of DNA-templated transcription
b0051028biological_processmRNA transport
b0051664biological_processnuclear pore localization
c0000781cellular_componentchromosome, telomeric region
c0000973biological_processpost-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
c0003723molecular_functionRNA binding
c0005515molecular_functionprotein binding
c0005634cellular_componentnucleus
c0005643cellular_componentnuclear pore
c0006302biological_processdouble-strand break repair
c0006405biological_processRNA export from nucleus
c0006409biological_processtRNA export from nucleus
c0006606biological_processprotein import into nucleus
c0006607biological_processNLS-bearing protein import into nucleus
c0006913biological_processnucleocytoplasmic transport
c0008139molecular_functionnuclear localization sequence binding
c0015031biological_processprotein transport
c0016020cellular_componentmembrane
c0016787molecular_functionhydrolase activity
c0016973biological_processpoly(A)+ mRNA export from nucleus
c0017056molecular_functionstructural constituent of nuclear pore
c0031080cellular_componentnuclear pore outer ring
c0031509biological_processsubtelomeric heterochromatin formation
c0031965cellular_componentnuclear membrane
c0034398biological_processtelomere tethering at nuclear periphery
c0036228biological_processprotein localization to nuclear inner membrane
c0044613cellular_componentnuclear pore central transport channel
c0044614cellular_componentnuclear pore cytoplasmic filaments
c0045893biological_processpositive regulation of DNA-templated transcription
c0046822biological_processregulation of nucleocytoplasmic transport
c0051028biological_processmRNA transport
c0051664biological_processnuclear pore localization
d0005198molecular_functionstructural molecule activity
d0005515molecular_functionprotein binding
d0005634cellular_componentnucleus
d0005635cellular_componentnuclear envelope
d0005643cellular_componentnuclear pore
d0005773cellular_componentvacuole
d0005774cellular_componentvacuolar membrane
d0005783cellular_componentendoplasmic reticulum
d0005789cellular_componentendoplasmic reticulum membrane
d0006606biological_processprotein import into nucleus
d0006913biological_processnucleocytoplasmic transport
d0012507cellular_componentER to Golgi transport vesicle membrane
d0015031biological_processprotein transport
d0016020cellular_componentmembrane
d0016192biological_processvesicle-mediated transport
d0030127cellular_componentCOPII vesicle coat
d0031080cellular_componentnuclear pore outer ring
d0031410cellular_componentcytoplasmic vesicle
d0032008biological_processpositive regulation of TOR signaling
d0032527biological_processprotein exit from endoplasmic reticulum
d0035859cellular_componentSeh1-associated complex
d0036503biological_processERAD pathway
d0045893biological_processpositive regulation of DNA-templated transcription
d0051028biological_processmRNA transport
d0051664biological_processnuclear pore localization
d0070863biological_processpositive regulation of protein exit from endoplasmic reticulum
d0071944cellular_componentcell periphery
d0090114biological_processCOPII-coated vesicle budding
d1902953biological_processpositive regulation of ER to Golgi vesicle-mediated transport
d1903432biological_processregulation of TORC1 signaling
d1904263biological_processpositive regulation of TORC1 signaling
e0005198molecular_functionstructural molecule activity
f0000781cellular_componentchromosome, telomeric region
f0000973biological_processpost-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
f0005515molecular_functionprotein binding
f0005634cellular_componentnucleus
f0005635cellular_componentnuclear envelope
f0005643cellular_componentnuclear pore
f0006302biological_processdouble-strand break repair
f0006406biological_processmRNA export from nucleus
f0006606biological_processprotein import into nucleus
f0006913biological_processnucleocytoplasmic transport
f0015031biological_processprotein transport
f0016020cellular_componentmembrane
f0017056molecular_functionstructural constituent of nuclear pore
f0030466biological_processsilent mating-type cassette heterochromatin formation
f0031080cellular_componentnuclear pore outer ring
f0031509biological_processsubtelomeric heterochromatin formation
f0031965cellular_componentnuclear membrane
f0031990biological_processmRNA export from nucleus in response to heat stress
f0034398biological_processtelomere tethering at nuclear periphery
f0042802molecular_functionidentical protein binding
f0045893biological_processpositive regulation of DNA-templated transcription
f0045944biological_processpositive regulation of transcription by RNA polymerase II
f0051028biological_processmRNA transport
f0051664biological_processnuclear pore localization
g0000122biological_processnegative regulation of transcription by RNA polymerase II
g0000781cellular_componentchromosome, telomeric region
g0000972biological_processtranscription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
g0000973biological_processpost-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
g0005515molecular_functionprotein binding
g0005634cellular_componentnucleus
g0005635cellular_componentnuclear envelope
g0005643cellular_componentnuclear pore
g0005829cellular_componentcytosol
g0006302biological_processdouble-strand break repair
g0006409biological_processtRNA export from nucleus
g0006606biological_processprotein import into nucleus
g0006913biological_processnucleocytoplasmic transport
g0015031biological_processprotein transport
g0016020cellular_componentmembrane
g0016973biological_processpoly(A)+ mRNA export from nucleus
g0017056molecular_functionstructural constituent of nuclear pore
g0030466biological_processsilent mating-type cassette heterochromatin formation
g0031080cellular_componentnuclear pore outer ring
g0031509biological_processsubtelomeric heterochromatin formation
g0031965cellular_componentnuclear membrane
g0031990biological_processmRNA export from nucleus in response to heat stress
g0034398biological_processtelomere tethering at nuclear periphery
g0034605biological_processcellular response to heat
g0045893biological_processpositive regulation of DNA-templated transcription
g0045944biological_processpositive regulation of transcription by RNA polymerase II
g0051028biological_processmRNA transport
g0051664biological_processnuclear pore localization
l0000055biological_processribosomal large subunit export from nucleus
l0000122biological_processnegative regulation of transcription by RNA polymerase II
l0000781cellular_componentchromosome, telomeric region
l0000973biological_processpost-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
l0005515molecular_functionprotein binding
l0005634cellular_componentnucleus
l0005635cellular_componentnuclear envelope
l0005643cellular_componentnuclear pore
l0006302biological_processdouble-strand break repair
l0006406biological_processmRNA export from nucleus
l0006606biological_processprotein import into nucleus
l0006611biological_processprotein export from nucleus
l0006913biological_processnucleocytoplasmic transport
l0015031biological_processprotein transport
l0016020cellular_componentmembrane
l0017056molecular_functionstructural constituent of nuclear pore
l0031080cellular_componentnuclear pore outer ring
l0031509biological_processsubtelomeric heterochromatin formation
l0031965cellular_componentnuclear membrane
l0031990biological_processmRNA export from nucleus in response to heat stress
l0033036biological_processmacromolecule localization
l0034398biological_processtelomere tethering at nuclear periphery
l0042802molecular_functionidentical protein binding
l0045893biological_processpositive regulation of DNA-templated transcription
l0045944biological_processpositive regulation of transcription by RNA polymerase II
l0051028biological_processmRNA transport
l0051664biological_processnuclear pore localization
l0071705biological_processnitrogen compound transport
m0000055biological_processribosomal large subunit export from nucleus
m0005515molecular_functionprotein binding
m0005634cellular_componentnucleus
m0005635cellular_componentnuclear envelope
m0005643cellular_componentnuclear pore
m0006406biological_processmRNA export from nucleus
m0006606biological_processprotein import into nucleus
m0006913biological_processnucleocytoplasmic transport
m0015031biological_processprotein transport
m0016020cellular_componentmembrane
m0017056molecular_functionstructural constituent of nuclear pore
m0031080cellular_componentnuclear pore outer ring
m0031965cellular_componentnuclear membrane
m0045893biological_processpositive regulation of DNA-templated transcription
m0051028biological_processmRNA transport
m0051664biological_processnuclear pore localization
n0000781cellular_componentchromosome, telomeric region
n0000973biological_processpost-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
n0003723molecular_functionRNA binding
n0005515molecular_functionprotein binding
n0005634cellular_componentnucleus
n0005643cellular_componentnuclear pore
n0006302biological_processdouble-strand break repair
n0006405biological_processRNA export from nucleus
n0006409biological_processtRNA export from nucleus
n0006606biological_processprotein import into nucleus
n0006607biological_processNLS-bearing protein import into nucleus
n0006913biological_processnucleocytoplasmic transport
n0008139molecular_functionnuclear localization sequence binding
n0015031biological_processprotein transport
n0016020cellular_componentmembrane
n0016787molecular_functionhydrolase activity
n0016973biological_processpoly(A)+ mRNA export from nucleus
n0017056molecular_functionstructural constituent of nuclear pore
n0031080cellular_componentnuclear pore outer ring
n0031509biological_processsubtelomeric heterochromatin formation
n0031965cellular_componentnuclear membrane
n0034398biological_processtelomere tethering at nuclear periphery
n0036228biological_processprotein localization to nuclear inner membrane
n0044613cellular_componentnuclear pore central transport channel
n0044614cellular_componentnuclear pore cytoplasmic filaments
n0045893biological_processpositive regulation of DNA-templated transcription
n0046822biological_processregulation of nucleocytoplasmic transport
n0051028biological_processmRNA transport
n0051664biological_processnuclear pore localization
o0005198molecular_functionstructural molecule activity
o0005515molecular_functionprotein binding
o0005634cellular_componentnucleus
o0005635cellular_componentnuclear envelope
o0005643cellular_componentnuclear pore
o0005773cellular_componentvacuole
o0005774cellular_componentvacuolar membrane
o0005783cellular_componentendoplasmic reticulum
o0005789cellular_componentendoplasmic reticulum membrane
o0006606biological_processprotein import into nucleus
o0006913biological_processnucleocytoplasmic transport
o0012507cellular_componentER to Golgi transport vesicle membrane
o0015031biological_processprotein transport
o0016020cellular_componentmembrane
o0016192biological_processvesicle-mediated transport
o0030127cellular_componentCOPII vesicle coat
o0031080cellular_componentnuclear pore outer ring
o0031410cellular_componentcytoplasmic vesicle
o0032008biological_processpositive regulation of TOR signaling
o0032527biological_processprotein exit from endoplasmic reticulum
o0035859cellular_componentSeh1-associated complex
o0036503biological_processERAD pathway
o0045893biological_processpositive regulation of DNA-templated transcription
o0051028biological_processmRNA transport
o0051664biological_processnuclear pore localization
o0070863biological_processpositive regulation of protein exit from endoplasmic reticulum
o0071944cellular_componentcell periphery
o0090114biological_processCOPII-coated vesicle budding
o1902953biological_processpositive regulation of ER to Golgi vesicle-mediated transport
o1903432biological_processregulation of TORC1 signaling
o1904263biological_processpositive regulation of TORC1 signaling
p0005198molecular_functionstructural molecule activity
q0000781cellular_componentchromosome, telomeric region
q0000973biological_processpost-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
q0005515molecular_functionprotein binding
q0005634cellular_componentnucleus
q0005635cellular_componentnuclear envelope
q0005643cellular_componentnuclear pore
q0006302biological_processdouble-strand break repair
q0006406biological_processmRNA export from nucleus
q0006606biological_processprotein import into nucleus
q0006913biological_processnucleocytoplasmic transport
q0015031biological_processprotein transport
q0016020cellular_componentmembrane
q0017056molecular_functionstructural constituent of nuclear pore
q0030466biological_processsilent mating-type cassette heterochromatin formation
q0031080cellular_componentnuclear pore outer ring
q0031509biological_processsubtelomeric heterochromatin formation
q0031965cellular_componentnuclear membrane
q0031990biological_processmRNA export from nucleus in response to heat stress
q0034398biological_processtelomere tethering at nuclear periphery
q0042802molecular_functionidentical protein binding
q0045893biological_processpositive regulation of DNA-templated transcription
q0045944biological_processpositive regulation of transcription by RNA polymerase II
q0051028biological_processmRNA transport
q0051664biological_processnuclear pore localization
r0000122biological_processnegative regulation of transcription by RNA polymerase II
r0000781cellular_componentchromosome, telomeric region
r0000972biological_processtranscription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
r0000973biological_processpost-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
r0005515molecular_functionprotein binding
r0005634cellular_componentnucleus
r0005635cellular_componentnuclear envelope
r0005643cellular_componentnuclear pore
r0005829cellular_componentcytosol
r0006302biological_processdouble-strand break repair
r0006409biological_processtRNA export from nucleus
r0006606biological_processprotein import into nucleus
r0006913biological_processnucleocytoplasmic transport
r0015031biological_processprotein transport
r0016020cellular_componentmembrane
r0016973biological_processpoly(A)+ mRNA export from nucleus
r0017056molecular_functionstructural constituent of nuclear pore
r0030466biological_processsilent mating-type cassette heterochromatin formation
r0031080cellular_componentnuclear pore outer ring
r0031509biological_processsubtelomeric heterochromatin formation
r0031965cellular_componentnuclear membrane
r0031990biological_processmRNA export from nucleus in response to heat stress
r0034398biological_processtelomere tethering at nuclear periphery
r0034605biological_processcellular response to heat
r0045893biological_processpositive regulation of DNA-templated transcription
r0045944biological_processpositive regulation of transcription by RNA polymerase II
r0051028biological_processmRNA transport
r0051664biological_processnuclear pore localization
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsMOD_RES: N-acetylserine => ECO:0007744|PubMed:22814378
ChainResidueDetails
gSER2
rSER2
cSER-202
cSER-192
nSER-333
nSER-203
nSER-202
nSER-192

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:17330950, ECO:0007744|PubMed:18407956, ECO:0007744|PubMed:19779198
ChainResidueDetails
cSER61
nSER61

site_idSWS_FT_FI3
Number of Residues4
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956, ECO:0007744|PubMed:19779198
ChainResidueDetails
cSER73
cSER83
nSER73
nSER83

site_idSWS_FT_FI4
Number of Residues2
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:17287358, ECO:0007744|PubMed:18407956
ChainResidueDetails
cTHR145
nTHR145

224004

PDB entries from 2024-08-21

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