Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

8THD

Structure of the Saccharomyces cerevisiae clamp unloader Elg1-RFC bound to PCNA

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0000077	biological_process	DNA damage checkpoint signaling
B	0003677	molecular_function	DNA binding
B	0003689	molecular_function	DNA clamp loader activity
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005634	cellular_component	nucleus
B	0005663	cellular_component	DNA replication factor C complex
B	0005829	cellular_component	cytosol
B	0006260	biological_process	DNA replication
B	0006261	biological_process	DNA-templated DNA replication
B	0006271	biological_process	DNA strand elongation involved in DNA replication
B	0006272	biological_process	leading strand elongation
B	0006281	biological_process	DNA repair
B	0007062	biological_process	sister chromatid cohesion
B	0007064	biological_process	mitotic sister chromatid cohesion
B	0031389	cellular_component	Rad17 RFC-like complex
B	0031390	cellular_component	Ctf18 RFC-like complex
B	0031391	cellular_component	Elg1 RFC-like complex
B	0090618	biological_process	DNA clamp unloading
C	0000077	biological_process	DNA damage checkpoint signaling
C	0003677	molecular_function	DNA binding
C	0003689	molecular_function	DNA clamp loader activity
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005634	cellular_component	nucleus
C	0005663	cellular_component	DNA replication factor C complex
C	0005829	cellular_component	cytosol
C	0006260	biological_process	DNA replication
C	0006261	biological_process	DNA-templated DNA replication
C	0006271	biological_process	DNA strand elongation involved in DNA replication
C	0006272	biological_process	leading strand elongation
C	0006281	biological_process	DNA repair
C	0006298	biological_process	mismatch repair
C	0007064	biological_process	mitotic sister chromatid cohesion
C	0016887	molecular_function	ATP hydrolysis activity
C	0031389	cellular_component	Rad17 RFC-like complex
C	0031390	cellular_component	Ctf18 RFC-like complex
C	0031391	cellular_component	Elg1 RFC-like complex
C	0090618	biological_process	DNA clamp unloading
D	0000076	biological_process	DNA replication checkpoint signaling
D	0000077	biological_process	DNA damage checkpoint signaling
D	0003677	molecular_function	DNA binding
D	0003689	molecular_function	DNA clamp loader activity
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005634	cellular_component	nucleus
D	0005663	cellular_component	DNA replication factor C complex
D	0006260	biological_process	DNA replication
D	0006261	biological_process	DNA-templated DNA replication
D	0006271	biological_process	DNA strand elongation involved in DNA replication
D	0006272	biological_process	leading strand elongation
D	0006281	biological_process	DNA repair
D	0006298	biological_process	mismatch repair
D	0007062	biological_process	sister chromatid cohesion
D	0007064	biological_process	mitotic sister chromatid cohesion
D	0031389	cellular_component	Rad17 RFC-like complex
D	0031390	cellular_component	Ctf18 RFC-like complex
D	0031391	cellular_component	Elg1 RFC-like complex
D	0090618	biological_process	DNA clamp unloading
E	0000077	biological_process	DNA damage checkpoint signaling
E	0003677	molecular_function	DNA binding
E	0003689	molecular_function	DNA clamp loader activity
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005634	cellular_component	nucleus
E	0005663	cellular_component	DNA replication factor C complex
E	0006260	biological_process	DNA replication
E	0006261	biological_process	DNA-templated DNA replication
E	0006271	biological_process	DNA strand elongation involved in DNA replication
E	0006272	biological_process	leading strand elongation
E	0006281	biological_process	DNA repair
E	0007062	biological_process	sister chromatid cohesion
E	0007064	biological_process	mitotic sister chromatid cohesion
E	0031389	cellular_component	Rad17 RFC-like complex
E	0031390	cellular_component	Ctf18 RFC-like complex
E	0031391	cellular_component	Elg1 RFC-like complex
E	0090618	biological_process	DNA clamp unloading
F	0003677	molecular_function	DNA binding
F	0005634	cellular_component	nucleus
F	0006260	biological_process	DNA replication
G	0003677	molecular_function	DNA binding
G	0005634	cellular_component	nucleus
G	0006260	biological_process	DNA replication
H	0003677	molecular_function	DNA binding
H	0005634	cellular_component	nucleus
H	0006260	biological_process	DNA replication

Functional Information from PROSITE/UniProt

site_id	PS00293
Number of Residues	19
Details	PCNA_2 Proliferating cell nuclear antigen signature 2. RCDHpvtLgmdLtSLsKIL

Chain	Residue	Details
F	ARG61-LEU79

site_id	PS01251
Number of Residues	24
Details	PCNA_1 Proliferating cell nuclear antigen signature 1. GIiAqAVDdSRVlLVsLeIgveaF

Chain	Residue	Details
F	GLY34-PHE57

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	57
Details	DNA_BIND: DNA_BIND => ECO:0000255

Chain	Residue	Details
F	ARG61-ARG80
G	ARG61-ARG80
H	ARG61-ARG80
E	ARG231
D	ARG229
C	ARG206

site_id	SWS_FT_FI2
Number of Residues	3
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) => ECO:0000269\|PubMed:15166219

Chain	Residue	Details
F	LYS127
G	LYS127
H	LYS127

site_id	SWS_FT_FI3
Number of Residues	6
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000269\|PubMed:12226657

Chain	Residue	Details
F	LYS164
G	LYS164
H	LYS164

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)