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8TGF

Crystal structure of cEPG5 LIR/LGG-1 complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0000045biological_processautophagosome assembly
A0000407cellular_componentphagophore assembly site
A0000421cellular_componentautophagosome membrane
A0000422biological_processautophagy of mitochondrion
A0001778biological_processplasma membrane repair
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0005739cellular_componentmitochondrion
A0005741cellular_componentmitochondrial outer membrane
A0005764cellular_componentlysosome
A0005776cellular_componentautophagosome
A0005886cellular_componentplasma membrane
A0006914biological_processautophagy
A0006995biological_processcellular response to nitrogen starvation
A0008340biological_processdetermination of adult lifespan
A0008429molecular_functionphosphatidylethanolamine binding
A0009408biological_processresponse to heat
A0012501biological_processprogrammed cell death
A0016236biological_processmacroautophagy
A0030425cellular_componentdendrite
A0030670cellular_componentphagocytic vesicle membrane
A0031410cellular_componentcytoplasmic vesicle
A0031625molecular_functionubiquitin protein ligase binding
A0040024biological_processdauer larval development
A0042995cellular_componentcell projection
A0043005cellular_componentneuron projection
A0043025cellular_componentneuronal cell body
A0043202cellular_componentlysosomal lumen
A0043204cellular_componentperikaryon
A0050811molecular_functionGABA receptor binding
A0050830biological_processdefense response to Gram-positive bacterium
A0070266biological_processnecroptotic process
A0097237biological_processcellular response to toxic substance
A0097352biological_processautophagosome maturation
A0098792biological_processxenophagy
A2000786biological_processpositive regulation of autophagosome assembly
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsSITE: Required for the interaction with unc-51 => ECO:0000269|PubMed:26687600
ChainResidueDetails
ATYR25
ALEU50
APHE104

site_idSWS_FT_FI2
Number of Residues1
DetailsSITE: Required for interaction with sqst-1 => ECO:0000269|PubMed:26687600
ChainResidueDetails
AARG28

site_idSWS_FT_FI3
Number of Residues1
DetailsSITE: Cleavage => ECO:0000269|PubMed:22767594, ECO:0000305|PubMed:20550938, ECO:0000305|PubMed:21802374
ChainResidueDetails
AGLY116

site_idSWS_FT_FI4
Number of Residues1
DetailsLIPID: Phosphatidylethanolamine amidated glycine => ECO:0000269|PubMed:22767594, ECO:0000305|PubMed:20550938, ECO:0000305|PubMed:21802374
ChainResidueDetails
AGLY116

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PDB entries from 2024-10-16

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