Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

8TFB

Cryo-EM structure of the Methanosarcina mazei apo glutamin synthetase structure: dodecameric form

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004356	molecular_function	glutamine synthetase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0006542	biological_process	glutamine biosynthetic process
A	0016874	molecular_function	ligase activity
A	0046872	molecular_function	metal ion binding
B	0003824	molecular_function	catalytic activity
B	0004356	molecular_function	glutamine synthetase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0006542	biological_process	glutamine biosynthetic process
B	0016874	molecular_function	ligase activity
B	0046872	molecular_function	metal ion binding
C	0003824	molecular_function	catalytic activity
C	0004356	molecular_function	glutamine synthetase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0006542	biological_process	glutamine biosynthetic process
C	0016874	molecular_function	ligase activity
C	0046872	molecular_function	metal ion binding
D	0003824	molecular_function	catalytic activity
D	0004356	molecular_function	glutamine synthetase activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0006542	biological_process	glutamine biosynthetic process
D	0016874	molecular_function	ligase activity
D	0046872	molecular_function	metal ion binding
L	0003824	molecular_function	catalytic activity
L	0004356	molecular_function	glutamine synthetase activity
L	0005524	molecular_function	ATP binding
L	0005737	cellular_component	cytoplasm
L	0006542	biological_process	glutamine biosynthetic process
L	0016874	molecular_function	ligase activity
L	0046872	molecular_function	metal ion binding
M	0003824	molecular_function	catalytic activity
M	0004356	molecular_function	glutamine synthetase activity
M	0005524	molecular_function	ATP binding
M	0005737	cellular_component	cytoplasm
M	0006542	biological_process	glutamine biosynthetic process
M	0016874	molecular_function	ligase activity
M	0046872	molecular_function	metal ion binding
O	0003824	molecular_function	catalytic activity
O	0004356	molecular_function	glutamine synthetase activity
O	0005524	molecular_function	ATP binding
O	0005737	cellular_component	cytoplasm
O	0006542	biological_process	glutamine biosynthetic process
O	0016874	molecular_function	ligase activity
O	0046872	molecular_function	metal ion binding
P	0003824	molecular_function	catalytic activity
P	0004356	molecular_function	glutamine synthetase activity
P	0005524	molecular_function	ATP binding
P	0005737	cellular_component	cytoplasm
P	0006542	biological_process	glutamine biosynthetic process
P	0016874	molecular_function	ligase activity
P	0046872	molecular_function	metal ion binding
Q	0003824	molecular_function	catalytic activity
Q	0004356	molecular_function	glutamine synthetase activity
Q	0005524	molecular_function	ATP binding
Q	0005737	cellular_component	cytoplasm
Q	0006542	biological_process	glutamine biosynthetic process
Q	0016874	molecular_function	ligase activity
Q	0046872	molecular_function	metal ion binding
V	0003824	molecular_function	catalytic activity
V	0004356	molecular_function	glutamine synthetase activity
V	0005524	molecular_function	ATP binding
V	0005737	cellular_component	cytoplasm
V	0006542	biological_process	glutamine biosynthetic process
V	0016874	molecular_function	ligase activity
V	0046872	molecular_function	metal ion binding
X	0003824	molecular_function	catalytic activity
X	0004356	molecular_function	glutamine synthetase activity
X	0005524	molecular_function	ATP binding
X	0005737	cellular_component	cytoplasm
X	0006542	biological_process	glutamine biosynthetic process
X	0016874	molecular_function	ligase activity
X	0046872	molecular_function	metal ion binding
Y	0003824	molecular_function	catalytic activity
Y	0004356	molecular_function	glutamine synthetase activity
Y	0005524	molecular_function	ATP binding
Y	0005737	cellular_component	cytoplasm
Y	0006542	biological_process	glutamine biosynthetic process
Y	0016874	molecular_function	ligase activity
Y	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00180
Number of Residues	19
Details	GLNA_1 Glutamine synthetase signature 1. FDGSSiqgftrieESDmkL

Chain	Residue	Details
A	PHE56-LEU74

site_id	PS00181
Number of Residues	16
Details	GLNA_ATP Glutamine synthetase putative ATP-binding region signature. KPLfgv..NGSGmHsnqS

Chain	Residue	Details
A	LYS237-SER252

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	84
Details	BINDING: BINDING => ECO:0000250\|UniProtKB:P12425

Chain	Residue	Details
A	GLU135
B	GLU192
B	GLU199
B	GLY244
B	HIS248
B	GLU336
C	GLU135
C	GLU137
C	GLU192
C	GLU199
C	GLY244
A	GLU137
C	HIS248
C	GLU336
D	GLU135
D	GLU137
D	GLU192
D	GLU199
D	GLY244
D	HIS248
D	GLU336
L	GLU135
A	GLU192
L	GLU137
L	GLU192
L	GLU199
L	GLY244
L	HIS248
L	GLU336
M	GLU135
M	GLU137
M	GLU192
M	GLU199
A	GLU199
M	GLY244
M	HIS248
M	GLU336
O	GLU135
O	GLU137
O	GLU192
O	GLU199
O	GLY244
O	HIS248
O	GLU336
A	GLY244
P	GLU135
P	GLU137
P	GLU192
P	GLU199
P	GLY244
P	HIS248
P	GLU336
Q	GLU135
Q	GLU137
Q	GLU192
A	HIS248
Q	GLU199
Q	GLY244
Q	HIS248
Q	GLU336
V	GLU135
V	GLU137
V	GLU192
V	GLU199
V	GLY244
V	HIS248
A	GLU336
V	GLU336
X	GLU135
X	GLU137
X	GLU192
X	GLU199
X	GLY244
X	HIS248
X	GLU336
Y	GLU135
Y	GLU137
B	GLU135
Y	GLU192
Y	GLU199
Y	GLY244
Y	HIS248
Y	GLU336
B	GLU137

site_id	SWS_FT_FI2
Number of Residues	48
Details	BINDING: BINDING => ECO:0000250\|UniProtKB:P9WN39

Chain	Residue	Details
A	GLU187
C	ASN243
C	ARG319
C	ARG324
D	GLU187
D	ASN243
D	ARG319
D	ARG324
L	GLU187
L	ASN243
L	ARG319
A	ASN243
L	ARG324
M	GLU187
M	ASN243
M	ARG319
M	ARG324
O	GLU187
O	ASN243
O	ARG319
O	ARG324
P	GLU187
A	ARG319
P	ASN243
P	ARG319
P	ARG324
Q	GLU187
Q	ASN243
Q	ARG319
Q	ARG324
V	GLU187
V	ASN243
V	ARG319
A	ARG324
V	ARG324
X	GLU187
X	ASN243
X	ARG319
X	ARG324
Y	GLU187
Y	ASN243
Y	ARG319
Y	ARG324
B	GLU187
B	ASN243
B	ARG319
B	ARG324
C	GLU187

site_id	SWS_FT_FI3
Number of Residues	12
Details	BINDING: BINDING => ECO:0000250\|UniProtKB:P77961

Chain	Residue	Details
A	SER252
V	SER252
X	SER252
Y	SER252
B	SER252
C	SER252
D	SER252
L	SER252
M	SER252
O	SER252
P	SER252
Q	SER252

site_id	SWS_FT_FI4
Number of Residues	36
Details	BINDING: BINDING => ECO:0000250\|UniProtKB:P0A1P6

Chain	Residue	Details
A	ARG301
D	ARG301
D	GLU307
D	ARG338
L	ARG301
L	GLU307
L	ARG338
M	ARG301
M	GLU307
M	ARG338
O	ARG301
A	GLU307
O	GLU307
O	ARG338
P	ARG301
P	GLU307
P	ARG338
Q	ARG301
Q	GLU307
Q	ARG338
V	ARG301
V	GLU307
A	ARG338
V	ARG338
X	ARG301
X	GLU307
X	ARG338
Y	ARG301
Y	GLU307
Y	ARG338
B	ARG301
B	GLU307
B	ARG338
C	ARG301
C	GLU307
C	ARG338

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)