8SZN

Crystal structure of Neisseria meningitidis ClpP protease in complex with phosphine oxide compound ACP6-12

Functional Information from PROSITE/UniProt

site_id	PS00381
Number of Residues	12
Details	CLP_PROTEASE_SER Endopeptidase Clp serine active site. TlcLGqAASMGA

Chain	Residue	Details
V	THR94-ALA105

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site_id	PS00382
Number of Residues	14
Details	CLP_PROTEASE_HIS Endopeptidase Clp histidine active site. RfalPnsrIMIHQP

Chain	Residue	Details
V	ARG116-PRO129

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	21
Details	ACT_SITE: Nucleophile => ECO:0000255|HAMAP-Rule:MF_00444

Chain	Residue	Details
V	SER102
C	SER102
D	SER102
E	SER102
F	SER102
G	SER102
H	SER102
I	SER102
J	SER102
K	SER102
L	SER102
W	SER102
M	SER102
N	SER102
X	SER102
Y	SER102
Z	SER102
a	SER102
b	SER102
A	SER102
B	SER102

---

site_id	SWS_FT_FI2
Number of Residues	21
Details	ACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_00444

Chain	Residue	Details
V	HIS127
C	HIS127
D	HIS127
E	HIS127
F	HIS127
G	HIS127
H	HIS127
I	HIS127
J	HIS127
K	HIS127
L	HIS127
W	HIS127
M	HIS127
N	HIS127
X	HIS127
Y	HIS127
Z	HIS127
a	HIS127
b	HIS127
A	HIS127
B	HIS127

---