8SZB

Cryo-EM Structure of NINJ2 Filament at 3.07 Angstrom Resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005886	cellular_component	plasma membrane
A	0007155	biological_process	cell adhesion
A	0007158	biological_process	neuron cell-cell adhesion
A	0007399	biological_process	nervous system development
A	0015485	molecular_function	cholesterol binding
A	0016020	cellular_component	membrane
A	0019835	biological_process	cytolysis
A	0042246	biological_process	tissue regeneration
A	0140912	molecular_function	membrane destabilizing activity
B	0005515	molecular_function	protein binding
B	0005886	cellular_component	plasma membrane
B	0007155	biological_process	cell adhesion
B	0007158	biological_process	neuron cell-cell adhesion
B	0007399	biological_process	nervous system development
B	0015485	molecular_function	cholesterol binding
B	0016020	cellular_component	membrane
B	0019835	biological_process	cytolysis
B	0042246	biological_process	tissue regeneration
B	0140912	molecular_function	membrane destabilizing activity
C	0005515	molecular_function	protein binding
C	0005886	cellular_component	plasma membrane
C	0007155	biological_process	cell adhesion
C	0007158	biological_process	neuron cell-cell adhesion
C	0007399	biological_process	nervous system development
C	0015485	molecular_function	cholesterol binding
C	0016020	cellular_component	membrane
C	0019835	biological_process	cytolysis
C	0042246	biological_process	tissue regeneration
C	0140912	molecular_function	membrane destabilizing activity
D	0005515	molecular_function	protein binding
D	0005886	cellular_component	plasma membrane
D	0007155	biological_process	cell adhesion
D	0007158	biological_process	neuron cell-cell adhesion
D	0007399	biological_process	nervous system development
D	0015485	molecular_function	cholesterol binding
D	0016020	cellular_component	membrane
D	0019835	biological_process	cytolysis
D	0042246	biological_process	tissue regeneration
D	0140912	molecular_function	membrane destabilizing activity
E	0005515	molecular_function	protein binding
E	0005886	cellular_component	plasma membrane
E	0007155	biological_process	cell adhesion
E	0007158	biological_process	neuron cell-cell adhesion
E	0007399	biological_process	nervous system development
E	0015485	molecular_function	cholesterol binding
E	0016020	cellular_component	membrane
E	0019835	biological_process	cytolysis
E	0042246	biological_process	tissue regeneration
E	0140912	molecular_function	membrane destabilizing activity
F	0005515	molecular_function	protein binding
F	0005886	cellular_component	plasma membrane
F	0007155	biological_process	cell adhesion
F	0007158	biological_process	neuron cell-cell adhesion
F	0007399	biological_process	nervous system development
F	0015485	molecular_function	cholesterol binding
F	0016020	cellular_component	membrane
F	0019835	biological_process	cytolysis
F	0042246	biological_process	tissue regeneration
F	0140912	molecular_function	membrane destabilizing activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	186
Details	Transmembrane: {"description":"Helical; Name=Helix alpha3","evidences":[{"source":"PubMed","id":"39667936","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8SZB","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	18
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"39667936","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8SZB","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	174
Details	Transmembrane: {"description":"Helical;Name=Helix alpha4","evidences":[{"source":"PubMed","id":"39667936","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8SZB","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	72
Details	Region: {"description":"Helix alpha1","evidences":[{"source":"PubMed","id":"39667936","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8SZB","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	114
Details	Region: {"description":"Helix alpha2","evidences":[{"source":"PubMed","id":"39667936","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8SZB","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"39667936","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8SZB","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---