8SRO
FoxP3 tetramer on TTTG repeats
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0043565 | molecular_function | sequence-specific DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0043565 | molecular_function | sequence-specific DNA binding |
| C | 0003700 | molecular_function | DNA-binding transcription factor activity |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0043565 | molecular_function | sequence-specific DNA binding |
| D | 0003700 | molecular_function | DNA-binding transcription factor activity |
| D | 0006355 | biological_process | regulation of DNA-templated transcription |
| D | 0043565 | molecular_function | sequence-specific DNA binding |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 100 |
| Details | ZN_FING: C2H2-type |
| Chain | Residue | Details |
| A | GLY196-HIS221 | |
| D | GLY196-HIS221 | |
| B | GLY196-HIS221 | |
| C | GLY196-HIS221 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 344 |
| Details | DNA_BIND: Fork-head => ECO:0000255|PROSITE-ProRule:PRU00089 |
| Chain | Residue | Details |
| A | ARG337-LYS423 | |
| D | ARG337-LYS423 | |
| B | ARG337-LYS423 | |
| C | ARG337-LYS423 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | SITE: Cleavage; by PCSK1 or PCSK2 => ECO:0000269|PubMed:19117830 |
| Chain | Residue | Details |
| A | ARG417 | |
| D | ARG417 | |
| B | ARG417 | |
| C | ARG417 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | MOD_RES: N6-acetyllysine; alternate => ECO:0000269|PubMed:22312127 |
| Chain | Residue | Details |
| A | LYS262 | |
| A | LYS267 | |
| D | LYS262 | |
| D | LYS267 | |
| B | LYS262 | |
| B | LYS267 | |
| C | LYS262 | |
| C | LYS267 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q9BZS1 |
| Chain | Residue | Details |
| A | SER418 | |
| D | SER418 | |
| B | SER418 | |
| C | SER418 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 16 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:23973222 |
| Chain | Residue | Details |
| A | LYS249 | |
| A | LYS251 | |
| A | LYS393 | |
| D | LYS249 | |
| D | LYS251 | |
| D | LYS393 | |
| B | LYS249 | |
| B | LYS251 | |
| B | LYS393 | |
| C | LYS249 | |
| C | LYS251 | |
| C | LYS393 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 8 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000269|PubMed:23973222 |
| Chain | Residue | Details |
| A | LYS262 | |
| A | LYS267 | |
| D | LYS262 | |
| D | LYS267 | |
| B | LYS262 | |
| B | LYS267 | |
| C | LYS262 | |
| C | LYS267 |
