8SDS

Crystal structure of PDC-3 Y221H beta-lactamase in complex with the boronic acid inhibitor LP-06

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008800	molecular_function	beta-lactamase activity
A	0017001	biological_process	antibiotic catabolic process
A	0030288	cellular_component	outer membrane-bounded periplasmic space

Functional Information from PROSITE/UniProt

site_id	PS00336
Number of Residues	8
Details	BETA_LACTAMASE_C Beta-lactamase class-C active site. FEIGSVSK

Chain	Residue	Details
A	PHE60-LYS67

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Acyl-ester intermediate => ECO:0000255|PROSITE-ProRule:PRU10102

Chain	Residue	Details
A	SER64

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site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000250

Chain	Residue	Details
A	TYR151

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site_id	SWS_FT_FI3
Number of Residues	5
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P00811

Chain	Residue	Details
A	SER64
A	GLN120
A	TYR151
A	ASN153
A	ASN344

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