8SBE

Structure of the rat vesicular glutamate transporter 2 determined by single-particle Cryo-EM

Replaces:  6V4D

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0022857	molecular_function	transmembrane transporter activity
A	0055085	biological_process	transmembrane transport

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	240
Details	TRANSMEM: Helical => ECO:0000255

Chain	Residue	Details
A	ILE72-GLY92
A	GLY410-PHE430
A	ILE444-VAL464
A	TYR478-ALA498
A	MET126-ALA146
A	LEU149-ILE169
A	GLY178-CYS198
A	THR217-VAL237
A	VAL245-TYR265
A	PRO311-ILE331
A	MET350-ALA370
A	ILE387-HIS407

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site_id	SWS_FT_FI2
Number of Residues	75
Details	TOPO_DOM: Vesicular => ECO:0000255

Chain	Residue	Details
A	VAL93-GLY125
A	PRO170-TYR177
A	GLN238-SER244
A	SER332-GLY349
A	THR408-ARG409
A	GLY465-GLN477

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site_id	SWS_FT_FI3
Number of Residues	89
Details	TOPO_DOM: Cytoplasmic => ECO:0000255

Chain	Residue	Details
A	SER147-ARG148
A	HIS199-THR216
A	GLU266-MET310
A	ASP371-LYS386
A	ASN431-SER443

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site_id	SWS_FT_FI4
Number of Residues	3
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ASN100
A	ASN101
A	ASN470

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