Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005509 | molecular_function | calcium ion binding |
A | 0043113 | biological_process | receptor clustering |
A | 0043236 | molecular_function | laminin binding |
B | 0005509 | molecular_function | calcium ion binding |
C | 0004672 | molecular_function | protein kinase activity |
C | 0004713 | molecular_function | protein tyrosine kinase activity |
C | 0005524 | molecular_function | ATP binding |
C | 0006468 | biological_process | protein phosphorylation |
Functional Information from PROSITE/UniProt
site_id | PS00010 |
Number of Residues | 12 |
Details | ASX_HYDROXYL Aspartic acid and asparagine hydroxylation site. CtNsegaFqCwC |
Chain | Residue | Details |
B | CYS409-CYS420 | |
site_id | PS00022 |
Number of Residues | 12 |
Details | EGF_1 EGF-like domain signature 1. CsCrpGvgGLrC |
Chain | Residue | Details |
A | CYS812-CYS823 | |
A | CYS866-CYS877 | |
A | CYS1355-CYS1366 | |
A | CYS1574-CYS1585 | |
A | CYS1613-CYS1624 | |
A | CYS1845-CYS1856 | |
site_id | PS00107 |
Number of Residues | 29 |
Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGEGAFGRVFqArapgllpyepftm.....VAVK |
Chain | Residue | Details |
C | ILE581-LYS609 | |
site_id | PS00109 |
Number of Residues | 13 |
Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. FVHrDLATRNCLV |
Chain | Residue | Details |
C | PHE721-VAL733 | |
site_id | PS00228 |
Number of Residues | 4 |
Details | TUBULIN_B_AUTOREG Tubulin-beta mRNA autoregulation signal. MREL |
Chain | Residue | Details |
C | MET1-LEU4 | |
site_id | PS01148 |
Number of Residues | 25 |
Details | UPF0033 Uncharacterized protein family UPF0033 signature. LDaeGsnCPaTkVfqgvlelegveG |
Chain | Residue | Details |
A | LEU1121-GLY1145 | |
site_id | PS01186 |
Number of Residues | 12 |
Details | EGF_2 EGF-like domain signature 2. ClCpgGFsgph....C |
Chain | Residue | Details |
A | CYS1845-CYS1856 | |
B | CYS378-CYS393 | |
B | CYS418-CYS433 | |
B | CYS722-CYS736 | |
site_id | PS01187 |
Number of Residues | 24 |
Details | EGF_CA Calcium-binding EGF-like domain signature. DvNECaeegy.........Csqg....CtNsegaFqC |
Chain | Residue | Details |
B | ASP395-CYS418 | |
site_id | PS01209 |
Number of Residues | 23 |
Details | LDLRA_1 LDL-receptor class A (LDLRA) domain signature. CIpaqwq.CDgdnDCgdhsDEDg....C |
Chain | Residue | Details |
B | CYS44-CYS66 | |
B | CYS83-CYS105 | |
B | CYS122-CYS143 | |
B | CYS160-CYS182 | |
B | CYS203-CYS225 | |
B | CYS243-CYS265 | |
B | CYS282-CYS304 | |
B | CYS324-CYS349 | |
site_id | PS01248 |
Number of Residues | 36 |
Details | EGF_LAM_1 Laminin-type EGF-like (LE) domain signature. Cs.CrpgvgGlrCdrCepgfWnfrgivtdgrsgctpC |
Chain | Residue | Details |
A | CYS812-CYS847 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 471 |
Details | TOPO_DOM: Extracellular => ECO:0000255 |
Chain | Residue | Details |
C | LEU24-THR495 | |
A | LEU1957 | |
A | GLN2007 | |
A | ASP2009 | |
site_id | SWS_FT_FI2 |
Number of Residues | 20 |
Details | TRANSMEM: Helical => ECO:0000255 |
Chain | Residue | Details |
C | VAL496-TYR516 | |
site_id | SWS_FT_FI3 |
Number of Residues | 352 |
Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
Chain | Residue | Details |
C | CYS517-VAL869 | |
Chain | Residue | Details |
C | ASP725 | |
B | ASN498 | |
B | ASN719 | |
B | ASN901 | |
B | ASN1077 | |
B | ASN1415 | |
B | ASN1467 | |
Chain | Residue | Details |
C | ILE581 | |
C | LYS609 | |
Chain | Residue | Details |
C | TYR554 | |
Chain | Residue | Details |
C | SER681 | |
C | SER698 | |
Chain | Residue | Details |
C | TYR755 | |
site_id | SWS_FT_FI9 |
Number of Residues | 1 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
Chain | Residue | Details |
C | ASN222 | |
A | SER676 | |
site_id | SWS_FT_FI10 |
Number of Residues | 1 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000250 |
Chain | Residue | Details |
C | ASN338 | |
site_id | SWS_FT_FI11 |
Number of Residues | 3 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
Chain | Residue | Details |
A | ASN250 | |
A | ASN777 | |
A | ASN932 | |
Chain | Residue | Details |
A | SER1835 | |