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8S92

Structure of N-terminal domains of Walker B mutated MCM8/9 heterohexamer complex with ADP

Functional Information from GO Data
ChainGOidnamespacecontents
A0000724biological_processdouble-strand break repair via homologous recombination
A0003677molecular_functionDNA binding
A0003682molecular_functionchromatin binding
A0003689molecular_functionDNA clamp loader activity
A0003697molecular_functionsingle-stranded DNA binding
A0004386molecular_functionhelicase activity
A0005515molecular_functionprotein binding
A0005524molecular_functionATP binding
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0005694cellular_componentchromosome
A0006260biological_processDNA replication
A0006281biological_processDNA repair
A0006310biological_processDNA recombination
A0006338biological_processchromatin remodeling
A0006974biological_processDNA damage response
A0007292biological_processfemale gamete generation
A0009378molecular_functionfour-way junction helicase activity
A0016787molecular_functionhydrolase activity
A0016887molecular_functionATP hydrolysis activity
A0017116molecular_functionsingle-stranded DNA helicase activity
A0019899molecular_functionenzyme binding
A0032406molecular_functionMutLbeta complex binding
A0032407molecular_functionMutSalpha complex binding
A0032408molecular_functionMutSbeta complex binding
A0032508biological_processDNA duplex unwinding
A0036121molecular_functiondouble-stranded DNA helicase activity
A0036298biological_processrecombinational interstrand cross-link repair
A0042555cellular_componentMCM complex
A0048232biological_processmale gamete generation
A0050821biological_processprotein stabilization
A0061749molecular_functionforked DNA-dependent helicase activity
A0061775molecular_functioncohesin loader activity
A0070716biological_processmismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication
A0071168biological_processprotein localization to chromatin
A0097362cellular_componentMCM8-MCM9 complex
A0140584molecular_functionchromatin extrusion motor activity
A0140588biological_processchromatin looping
A0140665molecular_functionATP-dependent H3-H4 histone complex chaperone activity
A0140849molecular_functionATP-dependent H2AZ histone chaperone activity
A1990518molecular_functionsingle-stranded 3'-5' DNA helicase activity
B0000724biological_processdouble-strand break repair via homologous recombination
B0003677molecular_functionDNA binding
B0003682molecular_functionchromatin binding
B0003689molecular_functionDNA clamp loader activity
B0003697molecular_functionsingle-stranded DNA binding
B0004386molecular_functionhelicase activity
B0005515molecular_functionprotein binding
B0005524molecular_functionATP binding
B0005634cellular_componentnucleus
B0005654cellular_componentnucleoplasm
B0005694cellular_componentchromosome
B0006260biological_processDNA replication
B0006281biological_processDNA repair
B0006310biological_processDNA recombination
B0006338biological_processchromatin remodeling
B0006974biological_processDNA damage response
B0007292biological_processfemale gamete generation
B0009378molecular_functionfour-way junction helicase activity
B0016787molecular_functionhydrolase activity
B0016887molecular_functionATP hydrolysis activity
B0017116molecular_functionsingle-stranded DNA helicase activity
B0019899molecular_functionenzyme binding
B0032406molecular_functionMutLbeta complex binding
B0032407molecular_functionMutSalpha complex binding
B0032408molecular_functionMutSbeta complex binding
B0032508biological_processDNA duplex unwinding
B0036121molecular_functiondouble-stranded DNA helicase activity
B0036298biological_processrecombinational interstrand cross-link repair
B0042555cellular_componentMCM complex
B0048232biological_processmale gamete generation
B0050821biological_processprotein stabilization
B0061749molecular_functionforked DNA-dependent helicase activity
B0061775molecular_functioncohesin loader activity
B0070716biological_processmismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication
B0071168biological_processprotein localization to chromatin
B0097362cellular_componentMCM8-MCM9 complex
B0140584molecular_functionchromatin extrusion motor activity
B0140588biological_processchromatin looping
B0140665molecular_functionATP-dependent H3-H4 histone complex chaperone activity
B0140849molecular_functionATP-dependent H2AZ histone chaperone activity
B1990518molecular_functionsingle-stranded 3'-5' DNA helicase activity
C0000724biological_processdouble-strand break repair via homologous recombination
C0003677molecular_functionDNA binding
C0003682molecular_functionchromatin binding
C0003689molecular_functionDNA clamp loader activity
C0003697molecular_functionsingle-stranded DNA binding
C0004386molecular_functionhelicase activity
C0005515molecular_functionprotein binding
C0005524molecular_functionATP binding
C0005634cellular_componentnucleus
C0005654cellular_componentnucleoplasm
C0005694cellular_componentchromosome
C0006260biological_processDNA replication
C0006281biological_processDNA repair
C0006310biological_processDNA recombination
C0006338biological_processchromatin remodeling
C0006974biological_processDNA damage response
C0007292biological_processfemale gamete generation
C0009378molecular_functionfour-way junction helicase activity
C0016787molecular_functionhydrolase activity
C0016887molecular_functionATP hydrolysis activity
C0017116molecular_functionsingle-stranded DNA helicase activity
C0019899molecular_functionenzyme binding
C0032406molecular_functionMutLbeta complex binding
C0032407molecular_functionMutSalpha complex binding
C0032408molecular_functionMutSbeta complex binding
C0032508biological_processDNA duplex unwinding
C0036121molecular_functiondouble-stranded DNA helicase activity
C0036298biological_processrecombinational interstrand cross-link repair
C0042555cellular_componentMCM complex
C0048232biological_processmale gamete generation
C0050821biological_processprotein stabilization
C0061749molecular_functionforked DNA-dependent helicase activity
C0061775molecular_functioncohesin loader activity
C0070716biological_processmismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication
C0071168biological_processprotein localization to chromatin
C0097362cellular_componentMCM8-MCM9 complex
C0140584molecular_functionchromatin extrusion motor activity
C0140588biological_processchromatin looping
C0140665molecular_functionATP-dependent H3-H4 histone complex chaperone activity
C0140849molecular_functionATP-dependent H2AZ histone chaperone activity
C1990518molecular_functionsingle-stranded 3'-5' DNA helicase activity
D0000724biological_processdouble-strand break repair via homologous recombination
D0003677molecular_functionDNA binding
D0003678molecular_functionDNA helicase activity
D0003682molecular_functionchromatin binding
D0003689molecular_functionDNA clamp loader activity
D0003697molecular_functionsingle-stranded DNA binding
D0004386molecular_functionhelicase activity
D0005515molecular_functionprotein binding
D0005524molecular_functionATP binding
D0005634cellular_componentnucleus
D0005694cellular_componentchromosome
D0006260biological_processDNA replication
D0006281biological_processDNA repair
D0006338biological_processchromatin remodeling
D0006974biological_processDNA damage response
D0007276biological_processgamete generation
D0007292biological_processfemale gamete generation
D0009378molecular_functionfour-way junction helicase activity
D0016787molecular_functionhydrolase activity
D0016887molecular_functionATP hydrolysis activity
D0017116molecular_functionsingle-stranded DNA helicase activity
D0019899molecular_functionenzyme binding
D0032406molecular_functionMutLbeta complex binding
D0032407molecular_functionMutSalpha complex binding
D0032408molecular_functionMutSbeta complex binding
D0032508biological_processDNA duplex unwinding
D0036121molecular_functiondouble-stranded DNA helicase activity
D0036298biological_processrecombinational interstrand cross-link repair
D0042555cellular_componentMCM complex
D0044877molecular_functionprotein-containing complex binding
D0061749molecular_functionforked DNA-dependent helicase activity
D0061775molecular_functioncohesin loader activity
D0070716biological_processmismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication
D0071168biological_processprotein localization to chromatin
D0097362cellular_componentMCM8-MCM9 complex
D0140584molecular_functionchromatin extrusion motor activity
D0140588biological_processchromatin looping
D0140665molecular_functionATP-dependent H3-H4 histone complex chaperone activity
D0140849molecular_functionATP-dependent H2AZ histone chaperone activity
D1990518molecular_functionsingle-stranded 3'-5' DNA helicase activity
E0000724biological_processdouble-strand break repair via homologous recombination
E0003677molecular_functionDNA binding
E0003678molecular_functionDNA helicase activity
E0003682molecular_functionchromatin binding
E0003689molecular_functionDNA clamp loader activity
E0003697molecular_functionsingle-stranded DNA binding
E0004386molecular_functionhelicase activity
E0005515molecular_functionprotein binding
E0005524molecular_functionATP binding
E0005634cellular_componentnucleus
E0005694cellular_componentchromosome
E0006260biological_processDNA replication
E0006281biological_processDNA repair
E0006338biological_processchromatin remodeling
E0006974biological_processDNA damage response
E0007276biological_processgamete generation
E0007292biological_processfemale gamete generation
E0009378molecular_functionfour-way junction helicase activity
E0016787molecular_functionhydrolase activity
E0016887molecular_functionATP hydrolysis activity
E0017116molecular_functionsingle-stranded DNA helicase activity
E0019899molecular_functionenzyme binding
E0032406molecular_functionMutLbeta complex binding
E0032407molecular_functionMutSalpha complex binding
E0032408molecular_functionMutSbeta complex binding
E0032508biological_processDNA duplex unwinding
E0036121molecular_functiondouble-stranded DNA helicase activity
E0036298biological_processrecombinational interstrand cross-link repair
E0042555cellular_componentMCM complex
E0044877molecular_functionprotein-containing complex binding
E0061749molecular_functionforked DNA-dependent helicase activity
E0061775molecular_functioncohesin loader activity
E0070716biological_processmismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication
E0071168biological_processprotein localization to chromatin
E0097362cellular_componentMCM8-MCM9 complex
E0140584molecular_functionchromatin extrusion motor activity
E0140588biological_processchromatin looping
E0140665molecular_functionATP-dependent H3-H4 histone complex chaperone activity
E0140849molecular_functionATP-dependent H2AZ histone chaperone activity
E1990518molecular_functionsingle-stranded 3'-5' DNA helicase activity
F0000724biological_processdouble-strand break repair via homologous recombination
F0003677molecular_functionDNA binding
F0003678molecular_functionDNA helicase activity
F0003682molecular_functionchromatin binding
F0003689molecular_functionDNA clamp loader activity
F0003697molecular_functionsingle-stranded DNA binding
F0004386molecular_functionhelicase activity
F0005515molecular_functionprotein binding
F0005524molecular_functionATP binding
F0005634cellular_componentnucleus
F0005694cellular_componentchromosome
F0006260biological_processDNA replication
F0006281biological_processDNA repair
F0006338biological_processchromatin remodeling
F0006974biological_processDNA damage response
F0007276biological_processgamete generation
F0007292biological_processfemale gamete generation
F0009378molecular_functionfour-way junction helicase activity
F0016787molecular_functionhydrolase activity
F0016887molecular_functionATP hydrolysis activity
F0017116molecular_functionsingle-stranded DNA helicase activity
F0019899molecular_functionenzyme binding
F0032406molecular_functionMutLbeta complex binding
F0032407molecular_functionMutSalpha complex binding
F0032408molecular_functionMutSbeta complex binding
F0032508biological_processDNA duplex unwinding
F0036121molecular_functiondouble-stranded DNA helicase activity
F0036298biological_processrecombinational interstrand cross-link repair
F0042555cellular_componentMCM complex
F0044877molecular_functionprotein-containing complex binding
F0061749molecular_functionforked DNA-dependent helicase activity
F0061775molecular_functioncohesin loader activity
F0070716biological_processmismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication
F0071168biological_processprotein localization to chromatin
F0097362cellular_componentMCM8-MCM9 complex
F0140584molecular_functionchromatin extrusion motor activity
F0140588biological_processchromatin looping
F0140665molecular_functionATP-dependent H3-H4 histone complex chaperone activity
F0140849molecular_functionATP-dependent H2AZ histone chaperone activity
F1990518molecular_functionsingle-stranded 3'-5' DNA helicase activity
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsBINDING: BINDING => ECO:0000255
ChainResidueDetails
DGLY352
EGLY352
FGLY352

site_idSWS_FT_FI2
Number of Residues3
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163
ChainResidueDetails
DSER762
ESER762
FSER762

site_idSWS_FT_FI3
Number of Residues6
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
DSER802
DSER1109
ESER802
ESER1109
FSER802
FSER1109

227344

PDB entries from 2024-11-13

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