8S8J
Structure of a yeast 48S-AUC preinitiation complex in closed conformation (model py48S-AUC-eIF5)
Functional Information from PROSITE/UniProt
| site_id | PS00052 |
| Number of Residues | 27 |
| Details | RIBOSOMAL_S7 Ribosomal protein S7 signature. ErLtnsLMmngrnnGKKlkavrIVkhT |
| Chain | Residue | Details |
| F | GLU93-THR119 |
| site_id | PS00053 |
| Number of Residues | 18 |
| Details | RIBOSOMAL_S8 Ribosomal protein S8 signature. GyvILTTSaGIMdheeAH |
| Chain | Residue | Details |
| W | GLY100-HIS117 |
| site_id | PS00054 |
| Number of Residues | 23 |
| Details | RIBOSOMAL_S11 Ribosomal protein S11 signature. LrALarS.GLrIgrieDvTPvPSD |
| Chain | Residue | Details |
| O | LEU102-ASP124 |
| site_id | PS00055 |
| Number of Residues | 8 |
| Details | RIBOSOMAL_S12 Ribosomal protein S12 signature. KqPNSAiR |
| Chain | Residue | Details |
| X | LYS62-ARG69 |
| site_id | PS00056 |
| Number of Residues | 13 |
| Details | RIBOSOMAL_S17 Ribosomal protein S17 signature. GDiVtVgQcRPIS |
| Chain | Residue | Details |
| L | GLY120-SER132 |
| site_id | PS00299 |
| Number of Residues | 26 |
| Details | UBIQUITIN_1 Ubiquitin domain signature. KskIqDkegIPpdqQrLIFaGkqleD |
| Chain | Residue | Details |
| f | LYS27-ASP52 |
| site_id | PS00323 |
| Number of Residues | 25 |
| Details | RIBOSOMAL_S19 Ribosomal protein S19 signature. NGKvfnqveIrpemVGhyLGEFsiT |
| Chain | Residue | Details |
| P | ASN98-THR122 |
| site_id | PS00360 |
| Number of Residues | 19 |
| Details | RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGhvSQvyAirqAiAKGL |
| Chain | Residue | Details |
| Q | GLY71-LEU89 |
| site_id | PS00362 |
| Number of Residues | 31 |
| Details | RIBOSOMAL_S15 Ribosomal protein S15 signature. VrkHLernRkDkdAkfrLilIesrihrLarY |
| Chain | Residue | Details |
| N | VAL98-TYR128 |
| site_id | PS00528 |
| Number of Residues | 15 |
| Details | RIBOSOMAL_S4E Ribosomal protein S4e signature. HlKRLAaPhhWmLdK |
| Chain | Residue | Details |
| E | HIS8-LYS22 |
| site_id | PS00529 |
| Number of Residues | 23 |
| Details | RIBOSOMAL_S24E Ribosomal protein S24e signature. YGggKStGFGlVYNSvadakkfE |
| Chain | Residue | Details |
| Y | TYR64-GLU86 |
| site_id | PS00548 |
| Number of Residues | 37 |
| Details | RIBOSOMAL_S3 Ribosomal protein S3 signature. AKsmkfadGfLihSgqpVndfIEtatrhvlLrqGvlG |
| Chain | Residue | Details |
| D | ALA147-GLY183 |
| site_id | PS00578 |
| Number of Residues | 12 |
| Details | RIBOSOMAL_S6E Ribosomal protein S6e signature. IAGGnDkqGfPM |
| Chain | Residue | Details |
| G | ILE52-MET63 |
| site_id | PS00585 |
| Number of Residues | 33 |
| Details | RIBOSOMAL_S5 Ribosomal protein S5 signature. GQrtrFkAvvVVGDsn.GhVGlGiktak.EVag.AI |
| Chain | Residue | Details |
| C | GLY98-ILE130 |
| site_id | PS00628 |
| Number of Residues | 20 |
| Details | RIBOSOMAL_S19E Ribosomal protein S19e signature. PhkhvdaSgsInRkVLQsLE |
| Chain | Residue | Details |
| T | PRO90-GLU109 |
| site_id | PS00632 |
| Number of Residues | 25 |
| Details | RIBOSOMAL_S4 Ribosomal protein S4 signature. LErRLqtqVYKlglAkSvhhARvLI |
| Chain | Residue | Details |
| J | LEU105-ILE129 |
| site_id | PS00646 |
| Number of Residues | 14 |
| Details | RIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGiRHfwGlrVRGQ |
| Chain | Residue | Details |
| S | ARG123-GLN136 |
| site_id | PS00678 |
| Number of Residues | 15 |
| Details | WD_REPEATS_1 Trp-Asp (WD) repeats signature. AVSAswDkTLRLWNL |
| Chain | Residue | Details |
| g | ALA81-LEU95 | |
| g | ILE123-THR137 | |
| g | ALA218-LEU232 |
| site_id | PS00712 |
| Number of Residues | 16 |
| Details | RIBOSOMAL_S17E Ribosomal protein S17e signature. IqSKrLRNkIAGYtTH |
| Chain | Residue | Details |
| R | ILE41-HIS56 |
| site_id | PS00733 |
| Number of Residues | 8 |
| Details | RIBOSOMAL_S26E Ribosomal protein S26e signature. YCISCAIH |
| Chain | Residue | Details |
| a | TYR73-HIS80 |
| site_id | PS00948 |
| Number of Residues | 14 |
| Details | RIBOSOMAL_S7E Ribosomal protein S7e signature. KLtRELEKKFQdRH |
| Chain | Residue | Details |
| H | LYS76-HIS89 |
| site_id | PS00961 |
| Number of Residues | 9 |
| Details | RIBOSOMAL_S28E Ribosomal protein S28e signature. ESEREARrL |
| Chain | Residue | Details |
| c | GLU58-LEU66 |
| site_id | PS00962 |
| Number of Residues | 12 |
| Details | RIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. AqLLLAARVHLG |
| Chain | Residue | Details |
| A | ALA14-GLY25 |
| site_id | PS00963 |
| Number of Residues | 25 |
| Details | RIBOSOMAL_S2_2 Ribosomal protein S2 signature 2. PrlVIVtDprsDaqaIkEssyvNIP |
| Chain | Residue | Details |
| A | PRO118-PRO142 |
| site_id | PS00996 |
| Number of Residues | 9 |
| Details | RIBOSOMAL_S21E Ribosomal protein S21e signature. LYVPRKCSA |
| Chain | Residue | Details |
| V | LEU11-ALA19 |
| site_id | PS01168 |
| Number of Residues | 33 |
| Details | RIBOSOMAL_S27E Ribosomal protein S27e signature. KCpgClnittvFShAqtavtCesCStvLctPtG |
| Chain | Residue | Details |
| b | LYS36-GLY68 |
| site_id | PS01189 |
| Number of Residues | 19 |
| Details | RIBOSOMAL_S12E Ribosomal protein S12e signature. ALKvvLrtSlvhDGLarGL |
| Chain | Residue | Details |
| M | ALA20-LEU38 |
| site_id | PS01191 |
| Number of Residues | 13 |
| Details | RIBOSOMAL_S3AE Ribosomal protein S3Ae signature. LkGRVvEvCLaDL |
| Chain | Residue | Details |
| B | LEU61-LEU73 |
| site_id | PS01193 |
| Number of Residues | 20 |
| Details | RIBOSOMAL_S8E Ribosomal protein S8e signature. RaaTGAkraqf.RkKrKfELG |
| Chain | Residue | Details |
| I | ARG11-GLY30 |
| site_id | PS01262 |
| Number of Residues | 23 |
| Details | IF1A Eukaryotic initiation factor 1A signature. MlGnGRveasCfDGnkRmaHIrG |
| Chain | Residue | Details |
| i | MET41-GLY63 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000255 |
| Chain | Residue | Details |
| m | GLY27 | |
| k | ASN249 | |
| k | SER284 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:19779198 |
| Chain | Residue | Details |
| m | SER170 | |
| m | SER172 | |
| f | LYS27 | |
| f | LYS29 | |
| f | LYS33 | |
| f | LYS63 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:17330950, ECO:0007744|PubMed:19779198 |
| Chain | Residue | Details |
| m | THR191 | |
| f | GLY76 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956 |
| Chain | Residue | Details |
| m | SER228 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18407956 |
| Chain | Residue | Details |
| m | THR317 | |
| l | SER118 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:17330950, ECO:0007744|PubMed:18407956, ECO:0007744|PubMed:19779198 |
| Chain | Residue | Details |
| m | SER397 |
