8S59

Cryo-EM structure of the active dodecameric Methanosarcina mazei glutamine synthetase.

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003824	molecular_function	catalytic activity
A	0004356	molecular_function	glutamine synthetase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0006542	biological_process	glutamine biosynthetic process
A	0016874	molecular_function	ligase activity
A	0046872	molecular_function	metal ion binding
B	0000166	molecular_function	nucleotide binding
B	0003824	molecular_function	catalytic activity
B	0004356	molecular_function	glutamine synthetase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0006542	biological_process	glutamine biosynthetic process
B	0016874	molecular_function	ligase activity
B	0046872	molecular_function	metal ion binding
C	0000166	molecular_function	nucleotide binding
C	0003824	molecular_function	catalytic activity
C	0004356	molecular_function	glutamine synthetase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0006542	biological_process	glutamine biosynthetic process
C	0016874	molecular_function	ligase activity
C	0046872	molecular_function	metal ion binding
D	0000166	molecular_function	nucleotide binding
D	0003824	molecular_function	catalytic activity
D	0004356	molecular_function	glutamine synthetase activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0006542	biological_process	glutamine biosynthetic process
D	0016874	molecular_function	ligase activity
D	0046872	molecular_function	metal ion binding
L	0000166	molecular_function	nucleotide binding
L	0003824	molecular_function	catalytic activity
L	0004356	molecular_function	glutamine synthetase activity
L	0005524	molecular_function	ATP binding
L	0005737	cellular_component	cytoplasm
L	0006542	biological_process	glutamine biosynthetic process
L	0016874	molecular_function	ligase activity
L	0046872	molecular_function	metal ion binding
M	0000166	molecular_function	nucleotide binding
M	0003824	molecular_function	catalytic activity
M	0004356	molecular_function	glutamine synthetase activity
M	0005524	molecular_function	ATP binding
M	0005737	cellular_component	cytoplasm
M	0006542	biological_process	glutamine biosynthetic process
M	0016874	molecular_function	ligase activity
M	0046872	molecular_function	metal ion binding
O	0000166	molecular_function	nucleotide binding
O	0003824	molecular_function	catalytic activity
O	0004356	molecular_function	glutamine synthetase activity
O	0005524	molecular_function	ATP binding
O	0005737	cellular_component	cytoplasm
O	0006542	biological_process	glutamine biosynthetic process
O	0016874	molecular_function	ligase activity
O	0046872	molecular_function	metal ion binding
P	0000166	molecular_function	nucleotide binding
P	0003824	molecular_function	catalytic activity
P	0004356	molecular_function	glutamine synthetase activity
P	0005524	molecular_function	ATP binding
P	0005737	cellular_component	cytoplasm
P	0006542	biological_process	glutamine biosynthetic process
P	0016874	molecular_function	ligase activity
P	0046872	molecular_function	metal ion binding
Q	0000166	molecular_function	nucleotide binding
Q	0003824	molecular_function	catalytic activity
Q	0004356	molecular_function	glutamine synthetase activity
Q	0005524	molecular_function	ATP binding
Q	0005737	cellular_component	cytoplasm
Q	0006542	biological_process	glutamine biosynthetic process
Q	0016874	molecular_function	ligase activity
Q	0046872	molecular_function	metal ion binding
V	0000166	molecular_function	nucleotide binding
V	0003824	molecular_function	catalytic activity
V	0004356	molecular_function	glutamine synthetase activity
V	0005524	molecular_function	ATP binding
V	0005737	cellular_component	cytoplasm
V	0006542	biological_process	glutamine biosynthetic process
V	0016874	molecular_function	ligase activity
V	0046872	molecular_function	metal ion binding
X	0000166	molecular_function	nucleotide binding
X	0003824	molecular_function	catalytic activity
X	0004356	molecular_function	glutamine synthetase activity
X	0005524	molecular_function	ATP binding
X	0005737	cellular_component	cytoplasm
X	0006542	biological_process	glutamine biosynthetic process
X	0016874	molecular_function	ligase activity
X	0046872	molecular_function	metal ion binding
Y	0000166	molecular_function	nucleotide binding
Y	0003824	molecular_function	catalytic activity
Y	0004356	molecular_function	glutamine synthetase activity
Y	0005524	molecular_function	ATP binding
Y	0005737	cellular_component	cytoplasm
Y	0006542	biological_process	glutamine biosynthetic process
Y	0016874	molecular_function	ligase activity
Y	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00180
Number of Residues	19
Details	GLNA_1 Glutamine synthetase signature 1. FDGSSiqgftrieESDmkL

Chain	Residue	Details
O	PHE56-LEU74

---

site_id	PS00181
Number of Residues	16
Details	GLNA_ATP Glutamine synthetase putative ATP-binding region signature. KPLfgv..NGSGmHsnqS

Chain	Residue	Details
O	LYS237-SER252

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1020
Details	Domain: {"description":"GS beta-grasp","evidences":[{"source":"PROSITE-ProRule","id":"PRU01330","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4020
Details	Domain: {"description":"GS catalytic","evidences":[{"source":"PROSITE-ProRule","id":"PRU01331","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	84
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P12425","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	48
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P9WN39","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P77961","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	36
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P0A1P6","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---