8RX5

Mycothione reductase from M. tuberculosis with FAD and NADPH

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004148	molecular_function	dihydrolipoyl dehydrogenase (NADH) activity
A	0005515	molecular_function	protein binding
A	0005829	cellular_component	cytosol
A	0006103	biological_process	2-oxoglutarate metabolic process
A	0010126	biological_process	mycothiol metabolic process
A	0016491	molecular_function	oxidoreductase activity
A	0050627	molecular_function	mycothione reductase [NAD(P)H] activity
A	0050660	molecular_function	flavin adenine dinucleotide binding
A	0070402	molecular_function	NADPH binding
B	0004148	molecular_function	dihydrolipoyl dehydrogenase (NADH) activity
B	0005515	molecular_function	protein binding
B	0005829	cellular_component	cytosol
B	0006103	biological_process	2-oxoglutarate metabolic process
B	0010126	biological_process	mycothiol metabolic process
B	0016491	molecular_function	oxidoreductase activity
B	0050627	molecular_function	mycothione reductase [NAD(P)H] activity
B	0050660	molecular_function	flavin adenine dinucleotide binding
B	0070402	molecular_function	NADPH binding
C	0004148	molecular_function	dihydrolipoyl dehydrogenase (NADH) activity
C	0005515	molecular_function	protein binding
C	0005829	cellular_component	cytosol
C	0006103	biological_process	2-oxoglutarate metabolic process
C	0010126	biological_process	mycothiol metabolic process
C	0016491	molecular_function	oxidoreductase activity
C	0050627	molecular_function	mycothione reductase [NAD(P)H] activity
C	0050660	molecular_function	flavin adenine dinucleotide binding
C	0070402	molecular_function	NADPH binding
D	0004148	molecular_function	dihydrolipoyl dehydrogenase (NADH) activity
D	0005515	molecular_function	protein binding
D	0005829	cellular_component	cytosol
D	0006103	biological_process	2-oxoglutarate metabolic process
D	0010126	biological_process	mycothiol metabolic process
D	0016491	molecular_function	oxidoreductase activity
D	0050627	molecular_function	mycothione reductase [NAD(P)H] activity
D	0050660	molecular_function	flavin adenine dinucleotide binding
D	0070402	molecular_function	NADPH binding
E	0004148	molecular_function	dihydrolipoyl dehydrogenase (NADH) activity
E	0005515	molecular_function	protein binding
E	0005829	cellular_component	cytosol
E	0006103	biological_process	2-oxoglutarate metabolic process
E	0010126	biological_process	mycothiol metabolic process
E	0016491	molecular_function	oxidoreductase activity
E	0050627	molecular_function	mycothione reductase [NAD(P)H] activity
E	0050660	molecular_function	flavin adenine dinucleotide binding
E	0070402	molecular_function	NADPH binding
F	0004148	molecular_function	dihydrolipoyl dehydrogenase (NADH) activity
F	0005515	molecular_function	protein binding
F	0005829	cellular_component	cytosol
F	0006103	biological_process	2-oxoglutarate metabolic process
F	0010126	biological_process	mycothiol metabolic process
F	0016491	molecular_function	oxidoreductase activity
F	0050627	molecular_function	mycothione reductase [NAD(P)H] activity
F	0050660	molecular_function	flavin adenine dinucleotide binding
F	0070402	molecular_function	NADPH binding

Functional Information from PROSITE/UniProt

site_id	PS00076
Number of Residues	11
Details	PYRIDINE_REDOX_1 Pyridine nucleotide-disulphide oxidoreductases class-I active site. GGtCLnvGCIP

Chain	Residue	Details
A	GLY36-PRO46

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Active site: {"description":"Proton acceptor"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	48
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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