8RWC
Crystal structure of the adenosine A2A receptor in complex with the synthetic photoswitch 'StilSwitch2
This is a non-PDB format compatible entry.
Functional Information from PROSITE/UniProt
| site_id | PS00237 |
| Number of Residues | 17 |
| Details | G_PROTEIN_RECEP_F1_1 G-protein coupled receptors family 1 signature. SSIfSLLAIAIDRYIaI |
| Chain | Residue | Details |
| A | SER90-ILE106 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 24 |
| Details | TRANSMEM: Helical; Name=1 |
| Chain | Residue | Details |
| A | VAL8-TRP32 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 28 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:18832607 |
| Chain | Residue | Details |
| A | LEU33-ASN42 | |
| A | ASP101-ARG120 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 23 |
| Details | TRANSMEM: Helical; Name=2 |
| Chain | Residue | Details |
| A | TYR43-ILE66 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 46 |
| Details | TOPO_DOM: Extracellular => ECO:0000269|PubMed:18832607 |
| Chain | Residue | Details |
| A | SER67-CYS77 | |
| A | ASN144-PRO173 | |
| A | CYS259-PRO266 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 22 |
| Details | TRANSMEM: Helical; Name=3 |
| Chain | Residue | Details |
| A | LEU78-ILE100 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 22 |
| Details | TRANSMEM: Helical; Name=4 |
| Chain | Residue | Details |
| A | ALA121-TRP143 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 24 |
| Details | TRANSMEM: Helical; Name=5 |
| Chain | Residue | Details |
| A | MET174-LEU198 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 23 |
| Details | TRANSMEM: Helical; Name=6 |
| Chain | Residue | Details |
| A | ALA235-PHE258 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 23 |
| Details | TRANSMEM: Helical; Name=7 |
| Chain | Residue | Details |
| A | LEU267-TYR290 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:21593763, ECO:0007744|PDB:2YDO |
| Chain | Residue | Details |
| A | GLU169 | |
| A | ASN253 | |
| A | SER277 | |
| A | HIS278 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ALA154 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 2 |
| Details | BINDING: axial binding residue |
| Chain | Residue | Details |
| A | TRP1007 | |
| A | ILE1102 |
