8RUY

Structure of IFTA and IFTB in Retrograde Intraflagellar transport trains

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005929	cellular_component	cilium
A	0008104	biological_process	intracellular protein localization
A	0030030	biological_process	cell projection organization
A	0030990	cellular_component	intraciliary transport particle
A	0030991	cellular_component	intraciliary transport particle A
A	0035721	biological_process	intraciliary retrograde transport
A	0044782	biological_process	cilium organization
A	0060271	biological_process	cilium assembly
B	0005929	cellular_component	cilium
B	0005930	cellular_component	axoneme
B	0030990	cellular_component	intraciliary transport particle
B	0030991	cellular_component	intraciliary transport particle A
B	0035721	biological_process	intraciliary retrograde transport
B	0036064	cellular_component	ciliary basal body
B	0044782	biological_process	cilium organization
C	0005929	cellular_component	cilium
C	0030991	cellular_component	intraciliary transport particle A
C	0035721	biological_process	intraciliary retrograde transport
C	0060271	biological_process	cilium assembly
C	0061512	biological_process	protein localization to cilium
C	0097730	cellular_component	non-motile cilium
C	1905515	biological_process	non-motile cilium assembly
D	0030030	biological_process	cell projection organization
D	0030991	cellular_component	intraciliary transport particle A
D	0035721	biological_process	intraciliary retrograde transport
D	0060271	biological_process	cilium assembly
D	0061512	biological_process	protein localization to cilium
D	0097730	cellular_component	non-motile cilium
D	1905515	biological_process	non-motile cilium assembly
E	0005929	cellular_component	cilium
E	0006396	biological_process	RNA processing
E	0030991	cellular_component	intraciliary transport particle A
E	0035721	biological_process	intraciliary retrograde transport
E	0061512	biological_process	protein localization to cilium
f	0005814	cellular_component	centriole
f	0019894	molecular_function	kinesin binding
f	0036064	cellular_component	ciliary basal body
f	0042073	biological_process	intraciliary transport
f	0097546	cellular_component	ciliary base
f	0097730	cellular_component	non-motile cilium
f	1905515	biological_process	non-motile cilium assembly
F	0005814	cellular_component	centriole
F	0019894	molecular_function	kinesin binding
F	0036064	cellular_component	ciliary basal body
F	0042073	biological_process	intraciliary transport
F	0097546	cellular_component	ciliary base
F	0097730	cellular_component	non-motile cilium
F	1905515	biological_process	non-motile cilium assembly
g	0005879	cellular_component	axonemal microtubule
g	0005929	cellular_component	cilium
g	0030030	biological_process	cell projection organization
g	0030992	cellular_component	intraciliary transport particle B
g	0042073	biological_process	intraciliary transport
g	0120170	molecular_function	intraciliary transport particle B binding
G	0005879	cellular_component	axonemal microtubule
G	0005929	cellular_component	cilium
G	0030030	biological_process	cell projection organization
G	0030992	cellular_component	intraciliary transport particle B
G	0042073	biological_process	intraciliary transport
G	0120170	molecular_function	intraciliary transport particle B binding
h	0005515	molecular_function	protein binding
h	0005814	cellular_component	centriole
h	0005929	cellular_component	cilium
h	0030992	cellular_component	intraciliary transport particle B
h	0031514	cellular_component	motile cilium
h	0042073	biological_process	intraciliary transport
h	0060271	biological_process	cilium assembly
H	0005515	molecular_function	protein binding
H	0005814	cellular_component	centriole
H	0005929	cellular_component	cilium
H	0030992	cellular_component	intraciliary transport particle B
H	0031514	cellular_component	motile cilium
H	0042073	biological_process	intraciliary transport
H	0060271	biological_process	cilium assembly
i	0030992	cellular_component	intraciliary transport particle B
i	0031514	cellular_component	motile cilium
i	0036064	cellular_component	ciliary basal body
I	0030992	cellular_component	intraciliary transport particle B
I	0031514	cellular_component	motile cilium
I	0036064	cellular_component	ciliary basal body
j	0005929	cellular_component	cilium
j	0030992	cellular_component	intraciliary transport particle B
j	0060271	biological_process	cilium assembly
J	0005929	cellular_component	cilium
J	0030992	cellular_component	intraciliary transport particle B
J	0060271	biological_process	cilium assembly
k	0005930	cellular_component	axoneme
k	0008017	molecular_function	microtubule binding
k	0010608	biological_process	post-transcriptional regulation of gene expression
k	0030030	biological_process	cell projection organization
k	0030992	cellular_component	intraciliary transport particle B
k	0036064	cellular_component	ciliary basal body
k	0042073	biological_process	intraciliary transport
k	0048513	biological_process	animal organ development
k	0048731	biological_process	system development
k	0060271	biological_process	cilium assembly
k	0060285	biological_process	cilium-dependent cell motility
k	0070507	biological_process	regulation of microtubule cytoskeleton organization
K	0005930	cellular_component	axoneme
K	0008017	molecular_function	microtubule binding
K	0010608	biological_process	post-transcriptional regulation of gene expression
K	0030030	biological_process	cell projection organization
K	0030992	cellular_component	intraciliary transport particle B
K	0036064	cellular_component	ciliary basal body
K	0042073	biological_process	intraciliary transport
K	0048513	biological_process	animal organ development
K	0048731	biological_process	system development
K	0060271	biological_process	cilium assembly
K	0060285	biological_process	cilium-dependent cell motility
K	0070507	biological_process	regulation of microtubule cytoskeleton organization
l	0005737	cellular_component	cytoplasm
l	0005929	cellular_component	cilium
l	0030990	cellular_component	intraciliary transport particle
l	0036064	cellular_component	ciliary basal body
l	0060271	biological_process	cilium assembly
l	0061512	biological_process	protein localization to cilium
l	0097546	cellular_component	ciliary base
l	0097730	cellular_component	non-motile cilium
L	0005737	cellular_component	cytoplasm
L	0005929	cellular_component	cilium
L	0030990	cellular_component	intraciliary transport particle
L	0036064	cellular_component	ciliary basal body
L	0060271	biological_process	cilium assembly
L	0061512	biological_process	protein localization to cilium
L	0097546	cellular_component	ciliary base
L	0097730	cellular_component	non-motile cilium
m	0005929	cellular_component	cilium
m	0036064	cellular_component	ciliary basal body
M	0005929	cellular_component	cilium
M	0036064	cellular_component	ciliary basal body
n	0005815	cellular_component	microtubule organizing center
n	0005929	cellular_component	cilium
n	0030030	biological_process	cell projection organization
n	0030992	cellular_component	intraciliary transport particle B
n	0060271	biological_process	cilium assembly
N	0005815	cellular_component	microtubule organizing center
N	0005929	cellular_component	cilium
N	0030030	biological_process	cell projection organization
N	0030992	cellular_component	intraciliary transport particle B
N	0060271	biological_process	cilium assembly
O	0005929	cellular_component	cilium
O	0030030	biological_process	cell projection organization
O	0030992	cellular_component	intraciliary transport particle B
O	0031514	cellular_component	motile cilium
O	0035735	biological_process	intraciliary transport involved in cilium assembly
O	0042073	biological_process	intraciliary transport
O	0048487	molecular_function	beta-tubulin binding
O	0060271	biological_process	cilium assembly
P	0005515	molecular_function	protein binding
P	0005929	cellular_component	cilium
P	0015631	molecular_function	tubulin binding
P	0030030	biological_process	cell projection organization
P	0030992	cellular_component	intraciliary transport particle B
P	0031514	cellular_component	motile cilium
P	0035735	biological_process	intraciliary transport involved in cilium assembly
P	0042073	biological_process	intraciliary transport
P	0045177	cellular_component	apical part of cell
P	0060271	biological_process	cilium assembly
Q	0000166	molecular_function	nucleotide binding
Q	0003924	molecular_function	GTPase activity
Q	0005515	molecular_function	protein binding
Q	0005525	molecular_function	GTP binding
Q	0030990	cellular_component	intraciliary transport particle
Q	0030992	cellular_component	intraciliary transport particle B
Q	0031514	cellular_component	motile cilium
R	0005515	molecular_function	protein binding
R	0030992	cellular_component	intraciliary transport particle B
R	0031514	cellular_component	motile cilium
R	0042073	biological_process	intraciliary transport
R	0046872	molecular_function	metal ion binding
s	0005515	molecular_function	protein binding
s	0005929	cellular_component	cilium
s	0015031	biological_process	protein transport
s	0030992	cellular_component	intraciliary transport particle B
s	0031514	cellular_component	motile cilium
s	0031647	biological_process	regulation of protein stability
s	0035082	biological_process	axoneme assembly
s	0036064	cellular_component	ciliary basal body
s	0036158	biological_process	outer dynein arm assembly
s	0042073	biological_process	intraciliary transport
s	0044782	biological_process	cilium organization
s	0050821	biological_process	protein stabilization
s	0060170	cellular_component	ciliary membrane
s	0060271	biological_process	cilium assembly
s	0060285	biological_process	cilium-dependent cell motility
s	0097546	cellular_component	ciliary base
s	0120025	cellular_component	plasma membrane bounded cell projection
s	1902017	biological_process	regulation of cilium assembly
S	0005515	molecular_function	protein binding
S	0005929	cellular_component	cilium
S	0015031	biological_process	protein transport
S	0030992	cellular_component	intraciliary transport particle B
S	0031514	cellular_component	motile cilium
S	0031647	biological_process	regulation of protein stability
S	0035082	biological_process	axoneme assembly
S	0036064	cellular_component	ciliary basal body
S	0036158	biological_process	outer dynein arm assembly
S	0042073	biological_process	intraciliary transport
S	0044782	biological_process	cilium organization
S	0050821	biological_process	protein stabilization
S	0060170	cellular_component	ciliary membrane
S	0060271	biological_process	cilium assembly
S	0060285	biological_process	cilium-dependent cell motility
S	0097546	cellular_component	ciliary base
S	0120025	cellular_component	plasma membrane bounded cell projection
S	1902017	biological_process	regulation of cilium assembly
T	0000166	molecular_function	nucleotide binding
T	0005525	molecular_function	GTP binding
T	0031514	cellular_component	motile cilium

Functional Information from PROSITE/UniProt

site_id	PS00139
Number of Residues	12
Details	THIOL_PROTEASE_CYS Eukaryotic thiol (cysteine) proteases cysteine active site. QDqLEHCWGqAA

Chain	Residue	Details
i	GLN1319-ALA1330

---

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. LAIGwkDgAISFWNA

Chain	Residue	Details
B	LEU76-ALA90

---

site_id	PS00806
Number of Residues	12
Details	ALDOLASE_CLASS_II_2 Fructose-bisphosphate aldolase class-II signature 2. MEkEMGefGSvE

Chain	Residue	Details
O	MET523-GLU534

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI13
Number of Residues	259
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	28
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21505417","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	78
Details	Repeat: {"description":"WD 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	78
Details	Repeat: {"description":"WD 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	84
Details	Repeat: {"description":"WD 3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	78
Details	Repeat: {"description":"WD 4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	80
Details	Repeat: {"description":"WD 5"}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	78
Details	Repeat: {"description":"WD 6"}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	76
Details	Repeat: {"description":"WD 7"}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	74
Details	Repeat: {"description":"WD 8"}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	62
Details	Repeat: {"description":"TPR 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	66
Details	Repeat: {"description":"TPR 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	68
Details	Repeat: {"description":"TPR 3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	66
Details	Repeat: {"description":"TPR 4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI28
Number of Residues	68
Details	Repeat: {"description":"TPR 5"}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	66
Details	Repeat: {"description":"TPR 6"}

Chain

Residue

Details

---

site_id	SWS_FT_FI30
Number of Residues	70
Details	Repeat: {"description":"TPR 7"}

Chain

Residue

Details

---

site_id	SWS_FT_FI31
Number of Residues	66
Details	Repeat: {"description":"TPR 8"}

Chain

Residue

Details

---

site_id	SWS_FT_FI32
Number of Residues	66
Details	Repeat: {"description":"TPR 9"}

Chain

Residue

Details

---

site_id	SWS_FT_FI33
Number of Residues	33
Details	Repeat: {"description":"TPR 10"}

Chain

Residue

Details

---

site_id	SWS_FT_FI34
Number of Residues	66
Details	Repeat: {"description":"TPR 11"}

Chain

Residue

Details

---

site_id	SWS_FT_FI35
Number of Residues	68
Details	Repeat: {"description":"TPR 12"}

Chain

Residue

Details

---

site_id	SWS_FT_FI36
Number of Residues	66
Details	Repeat: {"description":"TPR 13"}

Chain

Residue

Details

---