8RSX

TRYPTOPHAN SYNTHASE measured via serial crystallography from a silicon HARE-chip

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000162	biological_process	L-tryptophan biosynthetic process
A	0003824	molecular_function	catalytic activity
A	0004834	molecular_function	tryptophan synthase activity
A	0005515	molecular_function	protein binding
A	0005829	cellular_component	cytosol
A	0006568	biological_process	L-tryptophan metabolic process
A	0008652	biological_process	amino acid biosynthetic process
A	0009073	biological_process	aromatic amino acid family biosynthetic process
A	0016829	molecular_function	lyase activity
E	0000162	biological_process	L-tryptophan biosynthetic process
E	0004834	molecular_function	tryptophan synthase activity
E	0005515	molecular_function	protein binding
E	0005737	cellular_component	cytoplasm
E	0006568	biological_process	L-tryptophan metabolic process
E	0008652	biological_process	amino acid biosynthetic process
E	0009073	biological_process	aromatic amino acid family biosynthetic process
E	0016829	molecular_function	lyase activity
E	0042802	molecular_function	identical protein binding

Functional Information from PROSITE/UniProt

site_id	PS00167
Number of Residues	14
Details	TRP_SYNTHASE_ALPHA Tryptophan synthase alpha chain signature. LELGvPFSDPLADG

Chain	Residue	Details
A	LEU48-GLY61

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site_id	PS00168
Number of Residues	15
Details	TRP_SYNTHASE_BETA Tryptophan synthase beta chain pyridoxal-phosphate attachment site. LlHgGAHKtNqvLgQ

Chain	Residue	Details
E	LEU80-GLN94

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Proton acceptor"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"N6-(pyridoxal phosphate)lysine"}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues	3
Details	M-CSA 383

Chain	Residue	Details
A	GLU49	hydrogen bond acceptor, proton acceptor, proton donor
A	ASP60	hydrogen bond acceptor
A	TYR175	hydrogen bond donor

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