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8RRR

Alpha-synuclein amyloid fibril

Functional Information from GO Data
ChainGOidnamespacecontents
A0000122biological_processnegative regulation of transcription by RNA polymerase II
A0000149molecular_functionSNARE binding
A0000287molecular_functionmagnesium ion binding
A0000976molecular_functiontranscription cis-regulatory region binding
A0001774biological_processmicroglial cell activation
A0001921biological_processpositive regulation of receptor recycling
A0001956biological_processpositive regulation of neurotransmitter secretion
A0001963biological_processsynaptic transmission, dopaminergic
A0003779molecular_functionactin binding
A0004860molecular_functionprotein kinase inhibitor activity
A0005504molecular_functionfatty acid binding
A0005507molecular_functioncopper ion binding
A0005509molecular_functioncalcium ion binding
A0005515molecular_functionprotein binding
A0005543molecular_functionphospholipid binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0005739cellular_componentmitochondrion
A0005764cellular_componentlysosome
A0005829cellular_componentcytosol
A0005856cellular_componentcytoskeleton
A0005886cellular_componentplasma membrane
A0005938cellular_componentcell cortex
A0006469biological_processnegative regulation of protein kinase activity
A0006631biological_processfatty acid metabolic process
A0006638biological_processneutral lipid metabolic process
A0006644biological_processphospholipid metabolic process
A0006919biological_processactivation of cysteine-type endopeptidase activity involved in apoptotic process
A0007006biological_processmitochondrial membrane organization
A0007268biological_processchemical synaptic transmission
A0007269biological_processneurotransmitter secretion
A0008198molecular_functionferrous iron binding
A0008270molecular_functionzinc ion binding
A0008289molecular_functionlipid binding
A0008344biological_processadult locomotory behavior
A0009410biological_processresponse to xenobiotic stimulus
A0010040biological_processresponse to iron(II) ion
A0010517biological_processregulation of phospholipase activity
A0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
A0014048biological_processregulation of glutamate secretion
A0014059biological_processregulation of dopamine secretion
A0015629cellular_componentactin cytoskeleton
A0016020cellular_componentmembrane
A0016079biological_processsynaptic vesicle exocytosis
A0016082biological_processsynaptic vesicle priming
A0016234cellular_componentinclusion body
A0016491molecular_functionoxidoreductase activity
A0019894molecular_functionkinesin binding
A0022898biological_processregulation of transmembrane transporter activity
A0030424cellular_componentaxon
A0030426cellular_componentgrowth cone
A0030544molecular_functionHsp70 protein binding
A0030672cellular_componentsynaptic vesicle membrane
A0031092cellular_componentplatelet alpha granule membrane
A0031115biological_processnegative regulation of microtubule polymerization
A0031623biological_processreceptor internalization
A0031648biological_processprotein destabilization
A0032026biological_processresponse to magnesium ion
A0032410biological_processnegative regulation of transporter activity
A0032496biological_processresponse to lipopolysaccharide
A0032769biological_processnegative regulation of monooxygenase activity
A0032991cellular_componentprotein-containing complex
A0033138biological_processpositive regulation of peptidyl-serine phosphorylation
A0034341biological_processresponse to type II interferon
A0034599biological_processcellular response to oxidative stress
A0035493biological_processSNARE complex assembly
A0035543biological_processpositive regulation of SNARE complex assembly
A0040012biological_processregulation of locomotion
A0042393molecular_functionhistone binding
A0042416biological_processdopamine biosynthetic process
A0042417biological_processdopamine metabolic process
A0042775biological_processmitochondrial ATP synthesis coupled electron transport
A0042802molecular_functionidentical protein binding
A0042995cellular_componentcell projection
A0043014molecular_functionalpha-tubulin binding
A0043025cellular_componentneuronal cell body
A0043027molecular_functioncysteine-type endopeptidase inhibitor activity involved in apoptotic process
A0043030biological_processregulation of macrophage activation
A0043065biological_processpositive regulation of apoptotic process
A0043066biological_processnegative regulation of apoptotic process
A0043154biological_processnegative regulation of cysteine-type endopeptidase activity involved in apoptotic process
A0043524biological_processnegative regulation of neuron apoptotic process
A0043679cellular_componentaxon terminus
A0045202cellular_componentsynapse
A0045807biological_processpositive regulation of endocytosis
A0045920biological_processnegative regulation of exocytosis
A0045921biological_processpositive regulation of exocytosis
A0046872molecular_functionmetal ion binding
A0046928biological_processregulation of neurotransmitter secretion
A0048156molecular_functiontau protein binding
A0048168biological_processregulation of neuronal synaptic plasticity
A0048169biological_processregulation of long-term neuronal synaptic plasticity
A0048471cellular_componentperinuclear region of cytoplasm
A0048488biological_processsynaptic vesicle endocytosis
A0048489biological_processsynaptic vesicle transport
A0050729biological_processpositive regulation of inflammatory response
A0050806biological_processpositive regulation of synaptic transmission
A0050808biological_processsynapse organization
A0050812biological_processregulation of acyl-CoA biosynthetic process
A0051219molecular_functionphosphoprotein binding
A0051259biological_processprotein complex oligomerization
A0051262biological_processprotein tetramerization
A0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
A0051402biological_processneuron apoptotic process
A0051583biological_processdopamine uptake involved in synaptic transmission
A0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
A0051612biological_processnegative regulation of serotonin uptake
A0051621biological_processregulation of norepinephrine uptake
A0051622biological_processnegative regulation of norepinephrine uptake
A0055074biological_processcalcium ion homeostasis
A0060079biological_processexcitatory postsynaptic potential
A0060090molecular_functionmolecular adaptor activity
A0060291biological_processlong-term synaptic potentiation
A0060732biological_processpositive regulation of inositol phosphate biosynthetic process
A0060961molecular_functionphospholipase D inhibitor activity
A0061024biological_processmembrane organization
A0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
A0070555biological_processresponse to interleukin-1
A0070840molecular_functiondynein complex binding
A0071280biological_processcellular response to copper ion
A0071872biological_processcellular response to epinephrine stimulus
A0071902biological_processpositive regulation of protein serine/threonine kinase activity
A0097435biological_processsupramolecular fiber organization
A0098794cellular_componentpostsynapse
A0099512cellular_componentsupramolecular fiber
A1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
A1903136molecular_functioncuprous ion binding
A1903284biological_processpositive regulation of glutathione peroxidase activity
A1903285biological_processpositive regulation of hydrogen peroxide catabolic process
A1903421biological_processregulation of synaptic vesicle recycling
A1903426biological_processregulation of reactive oxygen species biosynthetic process
A1904377biological_processpositive regulation of protein localization to cell periphery
A1904715biological_processnegative regulation of chaperone-mediated autophagy
A1905606biological_processregulation of presynapse assembly
A1990000biological_processamyloid fibril formation
A2000377biological_processregulation of reactive oxygen species metabolic process
B0000122biological_processnegative regulation of transcription by RNA polymerase II
B0000149molecular_functionSNARE binding
B0000287molecular_functionmagnesium ion binding
B0000976molecular_functiontranscription cis-regulatory region binding
B0001774biological_processmicroglial cell activation
B0001921biological_processpositive regulation of receptor recycling
B0001956biological_processpositive regulation of neurotransmitter secretion
B0001963biological_processsynaptic transmission, dopaminergic
B0003779molecular_functionactin binding
B0004860molecular_functionprotein kinase inhibitor activity
B0005504molecular_functionfatty acid binding
B0005507molecular_functioncopper ion binding
B0005509molecular_functioncalcium ion binding
B0005515molecular_functionprotein binding
B0005543molecular_functionphospholipid binding
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0005634cellular_componentnucleus
B0005737cellular_componentcytoplasm
B0005739cellular_componentmitochondrion
B0005764cellular_componentlysosome
B0005829cellular_componentcytosol
B0005856cellular_componentcytoskeleton
B0005886cellular_componentplasma membrane
B0005938cellular_componentcell cortex
B0006469biological_processnegative regulation of protein kinase activity
B0006631biological_processfatty acid metabolic process
B0006638biological_processneutral lipid metabolic process
B0006644biological_processphospholipid metabolic process
B0006919biological_processactivation of cysteine-type endopeptidase activity involved in apoptotic process
B0007006biological_processmitochondrial membrane organization
B0007268biological_processchemical synaptic transmission
B0007269biological_processneurotransmitter secretion
B0008198molecular_functionferrous iron binding
B0008270molecular_functionzinc ion binding
B0008289molecular_functionlipid binding
B0008344biological_processadult locomotory behavior
B0009410biological_processresponse to xenobiotic stimulus
B0010040biological_processresponse to iron(II) ion
B0010517biological_processregulation of phospholipase activity
B0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
B0014048biological_processregulation of glutamate secretion
B0014059biological_processregulation of dopamine secretion
B0015629cellular_componentactin cytoskeleton
B0016020cellular_componentmembrane
B0016079biological_processsynaptic vesicle exocytosis
B0016082biological_processsynaptic vesicle priming
B0016234cellular_componentinclusion body
B0016491molecular_functionoxidoreductase activity
B0019894molecular_functionkinesin binding
B0022898biological_processregulation of transmembrane transporter activity
B0030424cellular_componentaxon
B0030426cellular_componentgrowth cone
B0030544molecular_functionHsp70 protein binding
B0030672cellular_componentsynaptic vesicle membrane
B0031092cellular_componentplatelet alpha granule membrane
B0031115biological_processnegative regulation of microtubule polymerization
B0031623biological_processreceptor internalization
B0031648biological_processprotein destabilization
B0032026biological_processresponse to magnesium ion
B0032410biological_processnegative regulation of transporter activity
B0032496biological_processresponse to lipopolysaccharide
B0032769biological_processnegative regulation of monooxygenase activity
B0032991cellular_componentprotein-containing complex
B0033138biological_processpositive regulation of peptidyl-serine phosphorylation
B0034341biological_processresponse to type II interferon
B0034599biological_processcellular response to oxidative stress
B0035493biological_processSNARE complex assembly
B0035543biological_processpositive regulation of SNARE complex assembly
B0040012biological_processregulation of locomotion
B0042393molecular_functionhistone binding
B0042416biological_processdopamine biosynthetic process
B0042417biological_processdopamine metabolic process
B0042775biological_processmitochondrial ATP synthesis coupled electron transport
B0042802molecular_functionidentical protein binding
B0042995cellular_componentcell projection
B0043014molecular_functionalpha-tubulin binding
B0043025cellular_componentneuronal cell body
B0043027molecular_functioncysteine-type endopeptidase inhibitor activity involved in apoptotic process
B0043030biological_processregulation of macrophage activation
B0043065biological_processpositive regulation of apoptotic process
B0043066biological_processnegative regulation of apoptotic process
B0043154biological_processnegative regulation of cysteine-type endopeptidase activity involved in apoptotic process
B0043524biological_processnegative regulation of neuron apoptotic process
B0043679cellular_componentaxon terminus
B0045202cellular_componentsynapse
B0045807biological_processpositive regulation of endocytosis
B0045920biological_processnegative regulation of exocytosis
B0045921biological_processpositive regulation of exocytosis
B0046872molecular_functionmetal ion binding
B0046928biological_processregulation of neurotransmitter secretion
B0048156molecular_functiontau protein binding
B0048168biological_processregulation of neuronal synaptic plasticity
B0048169biological_processregulation of long-term neuronal synaptic plasticity
B0048471cellular_componentperinuclear region of cytoplasm
B0048488biological_processsynaptic vesicle endocytosis
B0048489biological_processsynaptic vesicle transport
B0050729biological_processpositive regulation of inflammatory response
B0050806biological_processpositive regulation of synaptic transmission
B0050808biological_processsynapse organization
B0050812biological_processregulation of acyl-CoA biosynthetic process
B0051219molecular_functionphosphoprotein binding
B0051259biological_processprotein complex oligomerization
B0051262biological_processprotein tetramerization
B0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
B0051402biological_processneuron apoptotic process
B0051583biological_processdopamine uptake involved in synaptic transmission
B0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
B0051612biological_processnegative regulation of serotonin uptake
B0051621biological_processregulation of norepinephrine uptake
B0051622biological_processnegative regulation of norepinephrine uptake
B0055074biological_processcalcium ion homeostasis
B0060079biological_processexcitatory postsynaptic potential
B0060090molecular_functionmolecular adaptor activity
B0060291biological_processlong-term synaptic potentiation
B0060732biological_processpositive regulation of inositol phosphate biosynthetic process
B0060961molecular_functionphospholipase D inhibitor activity
B0061024biological_processmembrane organization
B0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
B0070555biological_processresponse to interleukin-1
B0070840molecular_functiondynein complex binding
B0071280biological_processcellular response to copper ion
B0071872biological_processcellular response to epinephrine stimulus
B0071902biological_processpositive regulation of protein serine/threonine kinase activity
B0097435biological_processsupramolecular fiber organization
B0098794cellular_componentpostsynapse
B0099512cellular_componentsupramolecular fiber
B1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
B1903136molecular_functioncuprous ion binding
B1903284biological_processpositive regulation of glutathione peroxidase activity
B1903285biological_processpositive regulation of hydrogen peroxide catabolic process
B1903421biological_processregulation of synaptic vesicle recycling
B1903426biological_processregulation of reactive oxygen species biosynthetic process
B1904377biological_processpositive regulation of protein localization to cell periphery
B1904715biological_processnegative regulation of chaperone-mediated autophagy
B1905606biological_processregulation of presynapse assembly
B1990000biological_processamyloid fibril formation
B2000377biological_processregulation of reactive oxygen species metabolic process
C0000122biological_processnegative regulation of transcription by RNA polymerase II
C0000149molecular_functionSNARE binding
C0000287molecular_functionmagnesium ion binding
C0000976molecular_functiontranscription cis-regulatory region binding
C0001774biological_processmicroglial cell activation
C0001921biological_processpositive regulation of receptor recycling
C0001956biological_processpositive regulation of neurotransmitter secretion
C0001963biological_processsynaptic transmission, dopaminergic
C0003779molecular_functionactin binding
C0004860molecular_functionprotein kinase inhibitor activity
C0005504molecular_functionfatty acid binding
C0005507molecular_functioncopper ion binding
C0005509molecular_functioncalcium ion binding
C0005515molecular_functionprotein binding
C0005543molecular_functionphospholipid binding
C0005576cellular_componentextracellular region
C0005615cellular_componentextracellular space
C0005634cellular_componentnucleus
C0005737cellular_componentcytoplasm
C0005739cellular_componentmitochondrion
C0005764cellular_componentlysosome
C0005829cellular_componentcytosol
C0005856cellular_componentcytoskeleton
C0005886cellular_componentplasma membrane
C0005938cellular_componentcell cortex
C0006469biological_processnegative regulation of protein kinase activity
C0006631biological_processfatty acid metabolic process
C0006638biological_processneutral lipid metabolic process
C0006644biological_processphospholipid metabolic process
C0006919biological_processactivation of cysteine-type endopeptidase activity involved in apoptotic process
C0007006biological_processmitochondrial membrane organization
C0007268biological_processchemical synaptic transmission
C0007269biological_processneurotransmitter secretion
C0008198molecular_functionferrous iron binding
C0008270molecular_functionzinc ion binding
C0008289molecular_functionlipid binding
C0008344biological_processadult locomotory behavior
C0009410biological_processresponse to xenobiotic stimulus
C0010040biological_processresponse to iron(II) ion
C0010517biological_processregulation of phospholipase activity
C0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
C0014048biological_processregulation of glutamate secretion
C0014059biological_processregulation of dopamine secretion
C0015629cellular_componentactin cytoskeleton
C0016020cellular_componentmembrane
C0016079biological_processsynaptic vesicle exocytosis
C0016082biological_processsynaptic vesicle priming
C0016234cellular_componentinclusion body
C0016491molecular_functionoxidoreductase activity
C0019894molecular_functionkinesin binding
C0022898biological_processregulation of transmembrane transporter activity
C0030424cellular_componentaxon
C0030426cellular_componentgrowth cone
C0030544molecular_functionHsp70 protein binding
C0030672cellular_componentsynaptic vesicle membrane
C0031092cellular_componentplatelet alpha granule membrane
C0031115biological_processnegative regulation of microtubule polymerization
C0031623biological_processreceptor internalization
C0031648biological_processprotein destabilization
C0032026biological_processresponse to magnesium ion
C0032410biological_processnegative regulation of transporter activity
C0032496biological_processresponse to lipopolysaccharide
C0032769biological_processnegative regulation of monooxygenase activity
C0032991cellular_componentprotein-containing complex
C0033138biological_processpositive regulation of peptidyl-serine phosphorylation
C0034341biological_processresponse to type II interferon
C0034599biological_processcellular response to oxidative stress
C0035493biological_processSNARE complex assembly
C0035543biological_processpositive regulation of SNARE complex assembly
C0040012biological_processregulation of locomotion
C0042393molecular_functionhistone binding
C0042416biological_processdopamine biosynthetic process
C0042417biological_processdopamine metabolic process
C0042775biological_processmitochondrial ATP synthesis coupled electron transport
C0042802molecular_functionidentical protein binding
C0042995cellular_componentcell projection
C0043014molecular_functionalpha-tubulin binding
C0043025cellular_componentneuronal cell body
C0043027molecular_functioncysteine-type endopeptidase inhibitor activity involved in apoptotic process
C0043030biological_processregulation of macrophage activation
C0043065biological_processpositive regulation of apoptotic process
C0043066biological_processnegative regulation of apoptotic process
C0043154biological_processnegative regulation of cysteine-type endopeptidase activity involved in apoptotic process
C0043524biological_processnegative regulation of neuron apoptotic process
C0043679cellular_componentaxon terminus
C0045202cellular_componentsynapse
C0045807biological_processpositive regulation of endocytosis
C0045920biological_processnegative regulation of exocytosis
C0045921biological_processpositive regulation of exocytosis
C0046872molecular_functionmetal ion binding
C0046928biological_processregulation of neurotransmitter secretion
C0048156molecular_functiontau protein binding
C0048168biological_processregulation of neuronal synaptic plasticity
C0048169biological_processregulation of long-term neuronal synaptic plasticity
C0048471cellular_componentperinuclear region of cytoplasm
C0048488biological_processsynaptic vesicle endocytosis
C0048489biological_processsynaptic vesicle transport
C0050729biological_processpositive regulation of inflammatory response
C0050806biological_processpositive regulation of synaptic transmission
C0050808biological_processsynapse organization
C0050812biological_processregulation of acyl-CoA biosynthetic process
C0051219molecular_functionphosphoprotein binding
C0051259biological_processprotein complex oligomerization
C0051262biological_processprotein tetramerization
C0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
C0051402biological_processneuron apoptotic process
C0051583biological_processdopamine uptake involved in synaptic transmission
C0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
C0051612biological_processnegative regulation of serotonin uptake
C0051621biological_processregulation of norepinephrine uptake
C0051622biological_processnegative regulation of norepinephrine uptake
C0055074biological_processcalcium ion homeostasis
C0060079biological_processexcitatory postsynaptic potential
C0060090molecular_functionmolecular adaptor activity
C0060291biological_processlong-term synaptic potentiation
C0060732biological_processpositive regulation of inositol phosphate biosynthetic process
C0060961molecular_functionphospholipase D inhibitor activity
C0061024biological_processmembrane organization
C0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
C0070555biological_processresponse to interleukin-1
C0070840molecular_functiondynein complex binding
C0071280biological_processcellular response to copper ion
C0071872biological_processcellular response to epinephrine stimulus
C0071902biological_processpositive regulation of protein serine/threonine kinase activity
C0097435biological_processsupramolecular fiber organization
C0098794cellular_componentpostsynapse
C0099512cellular_componentsupramolecular fiber
C1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
C1903136molecular_functioncuprous ion binding
C1903284biological_processpositive regulation of glutathione peroxidase activity
C1903285biological_processpositive regulation of hydrogen peroxide catabolic process
C1903421biological_processregulation of synaptic vesicle recycling
C1903426biological_processregulation of reactive oxygen species biosynthetic process
C1904377biological_processpositive regulation of protein localization to cell periphery
C1904715biological_processnegative regulation of chaperone-mediated autophagy
C1905606biological_processregulation of presynapse assembly
C1990000biological_processamyloid fibril formation
C2000377biological_processregulation of reactive oxygen species metabolic process
D0000122biological_processnegative regulation of transcription by RNA polymerase II
D0000149molecular_functionSNARE binding
D0000287molecular_functionmagnesium ion binding
D0000976molecular_functiontranscription cis-regulatory region binding
D0001774biological_processmicroglial cell activation
D0001921biological_processpositive regulation of receptor recycling
D0001956biological_processpositive regulation of neurotransmitter secretion
D0001963biological_processsynaptic transmission, dopaminergic
D0003779molecular_functionactin binding
D0004860molecular_functionprotein kinase inhibitor activity
D0005504molecular_functionfatty acid binding
D0005507molecular_functioncopper ion binding
D0005509molecular_functioncalcium ion binding
D0005515molecular_functionprotein binding
D0005543molecular_functionphospholipid binding
D0005576cellular_componentextracellular region
D0005615cellular_componentextracellular space
D0005634cellular_componentnucleus
D0005737cellular_componentcytoplasm
D0005739cellular_componentmitochondrion
D0005764cellular_componentlysosome
D0005829cellular_componentcytosol
D0005856cellular_componentcytoskeleton
D0005886cellular_componentplasma membrane
D0005938cellular_componentcell cortex
D0006469biological_processnegative regulation of protein kinase activity
D0006631biological_processfatty acid metabolic process
D0006638biological_processneutral lipid metabolic process
D0006644biological_processphospholipid metabolic process
D0006919biological_processactivation of cysteine-type endopeptidase activity involved in apoptotic process
D0007006biological_processmitochondrial membrane organization
D0007268biological_processchemical synaptic transmission
D0007269biological_processneurotransmitter secretion
D0008198molecular_functionferrous iron binding
D0008270molecular_functionzinc ion binding
D0008289molecular_functionlipid binding
D0008344biological_processadult locomotory behavior
D0009410biological_processresponse to xenobiotic stimulus
D0010040biological_processresponse to iron(II) ion
D0010517biological_processregulation of phospholipase activity
D0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
D0014048biological_processregulation of glutamate secretion
D0014059biological_processregulation of dopamine secretion
D0015629cellular_componentactin cytoskeleton
D0016020cellular_componentmembrane
D0016079biological_processsynaptic vesicle exocytosis
D0016082biological_processsynaptic vesicle priming
D0016234cellular_componentinclusion body
D0016491molecular_functionoxidoreductase activity
D0019894molecular_functionkinesin binding
D0022898biological_processregulation of transmembrane transporter activity
D0030424cellular_componentaxon
D0030426cellular_componentgrowth cone
D0030544molecular_functionHsp70 protein binding
D0030672cellular_componentsynaptic vesicle membrane
D0031092cellular_componentplatelet alpha granule membrane
D0031115biological_processnegative regulation of microtubule polymerization
D0031623biological_processreceptor internalization
D0031648biological_processprotein destabilization
D0032026biological_processresponse to magnesium ion
D0032410biological_processnegative regulation of transporter activity
D0032496biological_processresponse to lipopolysaccharide
D0032769biological_processnegative regulation of monooxygenase activity
D0032991cellular_componentprotein-containing complex
D0033138biological_processpositive regulation of peptidyl-serine phosphorylation
D0034341biological_processresponse to type II interferon
D0034599biological_processcellular response to oxidative stress
D0035493biological_processSNARE complex assembly
D0035543biological_processpositive regulation of SNARE complex assembly
D0040012biological_processregulation of locomotion
D0042393molecular_functionhistone binding
D0042416biological_processdopamine biosynthetic process
D0042417biological_processdopamine metabolic process
D0042775biological_processmitochondrial ATP synthesis coupled electron transport
D0042802molecular_functionidentical protein binding
D0042995cellular_componentcell projection
D0043014molecular_functionalpha-tubulin binding
D0043025cellular_componentneuronal cell body
D0043027molecular_functioncysteine-type endopeptidase inhibitor activity involved in apoptotic process
D0043030biological_processregulation of macrophage activation
D0043065biological_processpositive regulation of apoptotic process
D0043066biological_processnegative regulation of apoptotic process
D0043154biological_processnegative regulation of cysteine-type endopeptidase activity involved in apoptotic process
D0043524biological_processnegative regulation of neuron apoptotic process
D0043679cellular_componentaxon terminus
D0045202cellular_componentsynapse
D0045807biological_processpositive regulation of endocytosis
D0045920biological_processnegative regulation of exocytosis
D0045921biological_processpositive regulation of exocytosis
D0046872molecular_functionmetal ion binding
D0046928biological_processregulation of neurotransmitter secretion
D0048156molecular_functiontau protein binding
D0048168biological_processregulation of neuronal synaptic plasticity
D0048169biological_processregulation of long-term neuronal synaptic plasticity
D0048471cellular_componentperinuclear region of cytoplasm
D0048488biological_processsynaptic vesicle endocytosis
D0048489biological_processsynaptic vesicle transport
D0050729biological_processpositive regulation of inflammatory response
D0050806biological_processpositive regulation of synaptic transmission
D0050808biological_processsynapse organization
D0050812biological_processregulation of acyl-CoA biosynthetic process
D0051219molecular_functionphosphoprotein binding
D0051259biological_processprotein complex oligomerization
D0051262biological_processprotein tetramerization
D0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
D0051402biological_processneuron apoptotic process
D0051583biological_processdopamine uptake involved in synaptic transmission
D0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
D0051612biological_processnegative regulation of serotonin uptake
D0051621biological_processregulation of norepinephrine uptake
D0051622biological_processnegative regulation of norepinephrine uptake
D0055074biological_processcalcium ion homeostasis
D0060079biological_processexcitatory postsynaptic potential
D0060090molecular_functionmolecular adaptor activity
D0060291biological_processlong-term synaptic potentiation
D0060732biological_processpositive regulation of inositol phosphate biosynthetic process
D0060961molecular_functionphospholipase D inhibitor activity
D0061024biological_processmembrane organization
D0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
D0070555biological_processresponse to interleukin-1
D0070840molecular_functiondynein complex binding
D0071280biological_processcellular response to copper ion
D0071872biological_processcellular response to epinephrine stimulus
D0071902biological_processpositive regulation of protein serine/threonine kinase activity
D0097435biological_processsupramolecular fiber organization
D0098794cellular_componentpostsynapse
D0099512cellular_componentsupramolecular fiber
D1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
D1903136molecular_functioncuprous ion binding
D1903284biological_processpositive regulation of glutathione peroxidase activity
D1903285biological_processpositive regulation of hydrogen peroxide catabolic process
D1903421biological_processregulation of synaptic vesicle recycling
D1903426biological_processregulation of reactive oxygen species biosynthetic process
D1904377biological_processpositive regulation of protein localization to cell periphery
D1904715biological_processnegative regulation of chaperone-mediated autophagy
D1905606biological_processregulation of presynapse assembly
D1990000biological_processamyloid fibril formation
D2000377biological_processregulation of reactive oxygen species metabolic process
E0000122biological_processnegative regulation of transcription by RNA polymerase II
E0000149molecular_functionSNARE binding
E0000287molecular_functionmagnesium ion binding
E0000976molecular_functiontranscription cis-regulatory region binding
E0001774biological_processmicroglial cell activation
E0001921biological_processpositive regulation of receptor recycling
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E0009410biological_processresponse to xenobiotic stimulus
E0010040biological_processresponse to iron(II) ion
E0010517biological_processregulation of phospholipase activity
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E0014048biological_processregulation of glutamate secretion
E0014059biological_processregulation of dopamine secretion
E0015629cellular_componentactin cytoskeleton
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E0031623biological_processreceptor internalization
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E0032026biological_processresponse to magnesium ion
E0032410biological_processnegative regulation of transporter activity
E0032496biological_processresponse to lipopolysaccharide
E0032769biological_processnegative regulation of monooxygenase activity
E0032991cellular_componentprotein-containing complex
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E0034341biological_processresponse to type II interferon
E0034599biological_processcellular response to oxidative stress
E0035493biological_processSNARE complex assembly
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E0040012biological_processregulation of locomotion
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E0042775biological_processmitochondrial ATP synthesis coupled electron transport
E0042802molecular_functionidentical protein binding
E0042995cellular_componentcell projection
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E0043025cellular_componentneuronal cell body
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E0043065biological_processpositive regulation of apoptotic process
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E0043154biological_processnegative regulation of cysteine-type endopeptidase activity involved in apoptotic process
E0043524biological_processnegative regulation of neuron apoptotic process
E0043679cellular_componentaxon terminus
E0045202cellular_componentsynapse
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E0045921biological_processpositive regulation of exocytosis
E0046872molecular_functionmetal ion binding
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E0048156molecular_functiontau protein binding
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E0048169biological_processregulation of long-term neuronal synaptic plasticity
E0048471cellular_componentperinuclear region of cytoplasm
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E0048489biological_processsynaptic vesicle transport
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E0050806biological_processpositive regulation of synaptic transmission
E0050808biological_processsynapse organization
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E0051219molecular_functionphosphoprotein binding
E0051259biological_processprotein complex oligomerization
E0051262biological_processprotein tetramerization
E0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
E0051402biological_processneuron apoptotic process
E0051583biological_processdopamine uptake involved in synaptic transmission
E0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
E0051612biological_processnegative regulation of serotonin uptake
E0051621biological_processregulation of norepinephrine uptake
E0051622biological_processnegative regulation of norepinephrine uptake
E0055074biological_processcalcium ion homeostasis
E0060079biological_processexcitatory postsynaptic potential
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E0060291biological_processlong-term synaptic potentiation
E0060732biological_processpositive regulation of inositol phosphate biosynthetic process
E0060961molecular_functionphospholipase D inhibitor activity
E0061024biological_processmembrane organization
E0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
E0070555biological_processresponse to interleukin-1
E0070840molecular_functiondynein complex binding
E0071280biological_processcellular response to copper ion
E0071872biological_processcellular response to epinephrine stimulus
E0071902biological_processpositive regulation of protein serine/threonine kinase activity
E0097435biological_processsupramolecular fiber organization
E0098794cellular_componentpostsynapse
E0099512cellular_componentsupramolecular fiber
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E1904377biological_processpositive regulation of protein localization to cell periphery
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F0005507molecular_functioncopper ion binding
F0005509molecular_functioncalcium ion binding
F0005515molecular_functionprotein binding
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F0005615cellular_componentextracellular space
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F0005737cellular_componentcytoplasm
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F0005856cellular_componentcytoskeleton
F0005886cellular_componentplasma membrane
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F0006631biological_processfatty acid metabolic process
F0006638biological_processneutral lipid metabolic process
F0006644biological_processphospholipid metabolic process
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F0007006biological_processmitochondrial membrane organization
F0007268biological_processchemical synaptic transmission
F0007269biological_processneurotransmitter secretion
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F0008270molecular_functionzinc ion binding
F0008289molecular_functionlipid binding
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F0009410biological_processresponse to xenobiotic stimulus
F0010040biological_processresponse to iron(II) ion
F0010517biological_processregulation of phospholipase activity
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F0014048biological_processregulation of glutamate secretion
F0014059biological_processregulation of dopamine secretion
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F0030426cellular_componentgrowth cone
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F0031092cellular_componentplatelet alpha granule membrane
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F0031623biological_processreceptor internalization
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F0032026biological_processresponse to magnesium ion
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F0032496biological_processresponse to lipopolysaccharide
F0032769biological_processnegative regulation of monooxygenase activity
F0032991cellular_componentprotein-containing complex
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F0034341biological_processresponse to type II interferon
F0034599biological_processcellular response to oxidative stress
F0035493biological_processSNARE complex assembly
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F0042393molecular_functionhistone binding
F0042416biological_processdopamine biosynthetic process
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F0042775biological_processmitochondrial ATP synthesis coupled electron transport
F0042802molecular_functionidentical protein binding
F0042995cellular_componentcell projection
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F0043025cellular_componentneuronal cell body
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F0043154biological_processnegative regulation of cysteine-type endopeptidase activity involved in apoptotic process
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F0043679cellular_componentaxon terminus
F0045202cellular_componentsynapse
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F0046872molecular_functionmetal ion binding
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F0048156molecular_functiontau protein binding
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F0048169biological_processregulation of long-term neuronal synaptic plasticity
F0048471cellular_componentperinuclear region of cytoplasm
F0048488biological_processsynaptic vesicle endocytosis
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F0050729biological_processpositive regulation of inflammatory response
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F0050808biological_processsynapse organization
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F0051219molecular_functionphosphoprotein binding
F0051259biological_processprotein complex oligomerization
F0051262biological_processprotein tetramerization
F0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
F0051402biological_processneuron apoptotic process
F0051583biological_processdopamine uptake involved in synaptic transmission
F0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
F0051612biological_processnegative regulation of serotonin uptake
F0051621biological_processregulation of norepinephrine uptake
F0051622biological_processnegative regulation of norepinephrine uptake
F0055074biological_processcalcium ion homeostasis
F0060079biological_processexcitatory postsynaptic potential
F0060090molecular_functionmolecular adaptor activity
F0060291biological_processlong-term synaptic potentiation
F0060732biological_processpositive regulation of inositol phosphate biosynthetic process
F0060961molecular_functionphospholipase D inhibitor activity
F0061024biological_processmembrane organization
F0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
F0070555biological_processresponse to interleukin-1
F0070840molecular_functiondynein complex binding
F0071280biological_processcellular response to copper ion
F0071872biological_processcellular response to epinephrine stimulus
F0071902biological_processpositive regulation of protein serine/threonine kinase activity
F0097435biological_processsupramolecular fiber organization
F0098794cellular_componentpostsynapse
F0099512cellular_componentsupramolecular fiber
F1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
F1903136molecular_functioncuprous ion binding
F1903284biological_processpositive regulation of glutathione peroxidase activity
F1903285biological_processpositive regulation of hydrogen peroxide catabolic process
F1903421biological_processregulation of synaptic vesicle recycling
F1903426biological_processregulation of reactive oxygen species biosynthetic process
F1904377biological_processpositive regulation of protein localization to cell periphery
F1904715biological_processnegative regulation of chaperone-mediated autophagy
F1905606biological_processregulation of presynapse assembly
F1990000biological_processamyloid fibril formation
F2000377biological_processregulation of reactive oxygen species metabolic process
G0000122biological_processnegative regulation of transcription by RNA polymerase II
G0000149molecular_functionSNARE binding
G0000287molecular_functionmagnesium ion binding
G0000976molecular_functiontranscription cis-regulatory region binding
G0001774biological_processmicroglial cell activation
G0001921biological_processpositive regulation of receptor recycling
G0001956biological_processpositive regulation of neurotransmitter secretion
G0001963biological_processsynaptic transmission, dopaminergic
G0003779molecular_functionactin binding
G0004860molecular_functionprotein kinase inhibitor activity
G0005504molecular_functionfatty acid binding
G0005507molecular_functioncopper ion binding
G0005509molecular_functioncalcium ion binding
G0005515molecular_functionprotein binding
G0005543molecular_functionphospholipid binding
G0005576cellular_componentextracellular region
G0005615cellular_componentextracellular space
G0005634cellular_componentnucleus
G0005737cellular_componentcytoplasm
G0005739cellular_componentmitochondrion
G0005764cellular_componentlysosome
G0005829cellular_componentcytosol
G0005856cellular_componentcytoskeleton
G0005886cellular_componentplasma membrane
G0005938cellular_componentcell cortex
G0006469biological_processnegative regulation of protein kinase activity
G0006631biological_processfatty acid metabolic process
G0006638biological_processneutral lipid metabolic process
G0006644biological_processphospholipid metabolic process
G0006919biological_processactivation of cysteine-type endopeptidase activity involved in apoptotic process
G0007006biological_processmitochondrial membrane organization
G0007268biological_processchemical synaptic transmission
G0007269biological_processneurotransmitter secretion
G0008198molecular_functionferrous iron binding
G0008270molecular_functionzinc ion binding
G0008289molecular_functionlipid binding
G0008344biological_processadult locomotory behavior
G0009410biological_processresponse to xenobiotic stimulus
G0010040biological_processresponse to iron(II) ion
G0010517biological_processregulation of phospholipase activity
G0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
G0014048biological_processregulation of glutamate secretion
G0014059biological_processregulation of dopamine secretion
G0015629cellular_componentactin cytoskeleton
G0016020cellular_componentmembrane
G0016079biological_processsynaptic vesicle exocytosis
G0016082biological_processsynaptic vesicle priming
G0016234cellular_componentinclusion body
G0016491molecular_functionoxidoreductase activity
G0019894molecular_functionkinesin binding
G0022898biological_processregulation of transmembrane transporter activity
G0030424cellular_componentaxon
G0030426cellular_componentgrowth cone
G0030544molecular_functionHsp70 protein binding
G0030672cellular_componentsynaptic vesicle membrane
G0031092cellular_componentplatelet alpha granule membrane
G0031115biological_processnegative regulation of microtubule polymerization
G0031623biological_processreceptor internalization
G0031648biological_processprotein destabilization
G0032026biological_processresponse to magnesium ion
G0032410biological_processnegative regulation of transporter activity
G0032496biological_processresponse to lipopolysaccharide
G0032769biological_processnegative regulation of monooxygenase activity
G0032991cellular_componentprotein-containing complex
G0033138biological_processpositive regulation of peptidyl-serine phosphorylation
G0034341biological_processresponse to type II interferon
G0034599biological_processcellular response to oxidative stress
G0035493biological_processSNARE complex assembly
G0035543biological_processpositive regulation of SNARE complex assembly
G0040012biological_processregulation of locomotion
G0042393molecular_functionhistone binding
G0042416biological_processdopamine biosynthetic process
G0042417biological_processdopamine metabolic process
G0042775biological_processmitochondrial ATP synthesis coupled electron transport
G0042802molecular_functionidentical protein binding
G0042995cellular_componentcell projection
G0043014molecular_functionalpha-tubulin binding
G0043025cellular_componentneuronal cell body
G0043027molecular_functioncysteine-type endopeptidase inhibitor activity involved in apoptotic process
G0043030biological_processregulation of macrophage activation
G0043065biological_processpositive regulation of apoptotic process
G0043066biological_processnegative regulation of apoptotic process
G0043154biological_processnegative regulation of cysteine-type endopeptidase activity involved in apoptotic process
G0043524biological_processnegative regulation of neuron apoptotic process
G0043679cellular_componentaxon terminus
G0045202cellular_componentsynapse
G0045807biological_processpositive regulation of endocytosis
G0045920biological_processnegative regulation of exocytosis
G0045921biological_processpositive regulation of exocytosis
G0046872molecular_functionmetal ion binding
G0046928biological_processregulation of neurotransmitter secretion
G0048156molecular_functiontau protein binding
G0048168biological_processregulation of neuronal synaptic plasticity
G0048169biological_processregulation of long-term neuronal synaptic plasticity
G0048471cellular_componentperinuclear region of cytoplasm
G0048488biological_processsynaptic vesicle endocytosis
G0048489biological_processsynaptic vesicle transport
G0050729biological_processpositive regulation of inflammatory response
G0050806biological_processpositive regulation of synaptic transmission
G0050808biological_processsynapse organization
G0050812biological_processregulation of acyl-CoA biosynthetic process
G0051219molecular_functionphosphoprotein binding
G0051259biological_processprotein complex oligomerization
G0051262biological_processprotein tetramerization
G0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
G0051402biological_processneuron apoptotic process
G0051583biological_processdopamine uptake involved in synaptic transmission
G0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
G0051612biological_processnegative regulation of serotonin uptake
G0051621biological_processregulation of norepinephrine uptake
G0051622biological_processnegative regulation of norepinephrine uptake
G0055074biological_processcalcium ion homeostasis
G0060079biological_processexcitatory postsynaptic potential
G0060090molecular_functionmolecular adaptor activity
G0060291biological_processlong-term synaptic potentiation
G0060732biological_processpositive regulation of inositol phosphate biosynthetic process
G0060961molecular_functionphospholipase D inhibitor activity
G0061024biological_processmembrane organization
G0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
G0070555biological_processresponse to interleukin-1
G0070840molecular_functiondynein complex binding
G0071280biological_processcellular response to copper ion
G0071872biological_processcellular response to epinephrine stimulus
G0071902biological_processpositive regulation of protein serine/threonine kinase activity
G0097435biological_processsupramolecular fiber organization
G0098794cellular_componentpostsynapse
G0099512cellular_componentsupramolecular fiber
G1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
G1903136molecular_functioncuprous ion binding
G1903284biological_processpositive regulation of glutathione peroxidase activity
G1903285biological_processpositive regulation of hydrogen peroxide catabolic process
G1903421biological_processregulation of synaptic vesicle recycling
G1903426biological_processregulation of reactive oxygen species biosynthetic process
G1904377biological_processpositive regulation of protein localization to cell periphery
G1904715biological_processnegative regulation of chaperone-mediated autophagy
G1905606biological_processregulation of presynapse assembly
G1990000biological_processamyloid fibril formation
G2000377biological_processregulation of reactive oxygen species metabolic process
H0000122biological_processnegative regulation of transcription by RNA polymerase II
H0000149molecular_functionSNARE binding
H0000287molecular_functionmagnesium ion binding
H0000976molecular_functiontranscription cis-regulatory region binding
H0001774biological_processmicroglial cell activation
H0001921biological_processpositive regulation of receptor recycling
H0001956biological_processpositive regulation of neurotransmitter secretion
H0001963biological_processsynaptic transmission, dopaminergic
H0003779molecular_functionactin binding
H0004860molecular_functionprotein kinase inhibitor activity
H0005504molecular_functionfatty acid binding
H0005507molecular_functioncopper ion binding
H0005509molecular_functioncalcium ion binding
H0005515molecular_functionprotein binding
H0005543molecular_functionphospholipid binding
H0005576cellular_componentextracellular region
H0005615cellular_componentextracellular space
H0005634cellular_componentnucleus
H0005737cellular_componentcytoplasm
H0005739cellular_componentmitochondrion
H0005764cellular_componentlysosome
H0005829cellular_componentcytosol
H0005856cellular_componentcytoskeleton
H0005886cellular_componentplasma membrane
H0005938cellular_componentcell cortex
H0006469biological_processnegative regulation of protein kinase activity
H0006631biological_processfatty acid metabolic process
H0006638biological_processneutral lipid metabolic process
H0006644biological_processphospholipid metabolic process
H0006919biological_processactivation of cysteine-type endopeptidase activity involved in apoptotic process
H0007006biological_processmitochondrial membrane organization
H0007268biological_processchemical synaptic transmission
H0007269biological_processneurotransmitter secretion
H0008198molecular_functionferrous iron binding
H0008270molecular_functionzinc ion binding
H0008289molecular_functionlipid binding
H0008344biological_processadult locomotory behavior
H0009410biological_processresponse to xenobiotic stimulus
H0010040biological_processresponse to iron(II) ion
H0010517biological_processregulation of phospholipase activity
H0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
H0014048biological_processregulation of glutamate secretion
H0014059biological_processregulation of dopamine secretion
H0015629cellular_componentactin cytoskeleton
H0016020cellular_componentmembrane
H0016079biological_processsynaptic vesicle exocytosis
H0016082biological_processsynaptic vesicle priming
H0016234cellular_componentinclusion body
H0016491molecular_functionoxidoreductase activity
H0019894molecular_functionkinesin binding
H0022898biological_processregulation of transmembrane transporter activity
H0030424cellular_componentaxon
H0030426cellular_componentgrowth cone
H0030544molecular_functionHsp70 protein binding
H0030672cellular_componentsynaptic vesicle membrane
H0031092cellular_componentplatelet alpha granule membrane
H0031115biological_processnegative regulation of microtubule polymerization
H0031623biological_processreceptor internalization
H0031648biological_processprotein destabilization
H0032026biological_processresponse to magnesium ion
H0032410biological_processnegative regulation of transporter activity
H0032496biological_processresponse to lipopolysaccharide
H0032769biological_processnegative regulation of monooxygenase activity
H0032991cellular_componentprotein-containing complex
H0033138biological_processpositive regulation of peptidyl-serine phosphorylation
H0034341biological_processresponse to type II interferon
H0034599biological_processcellular response to oxidative stress
H0035493biological_processSNARE complex assembly
H0035543biological_processpositive regulation of SNARE complex assembly
H0040012biological_processregulation of locomotion
H0042393molecular_functionhistone binding
H0042416biological_processdopamine biosynthetic process
H0042417biological_processdopamine metabolic process
H0042775biological_processmitochondrial ATP synthesis coupled electron transport
H0042802molecular_functionidentical protein binding
H0042995cellular_componentcell projection
H0043014molecular_functionalpha-tubulin binding
H0043025cellular_componentneuronal cell body
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H0043030biological_processregulation of macrophage activation
H0043065biological_processpositive regulation of apoptotic process
H0043066biological_processnegative regulation of apoptotic process
H0043154biological_processnegative regulation of cysteine-type endopeptidase activity involved in apoptotic process
H0043524biological_processnegative regulation of neuron apoptotic process
H0043679cellular_componentaxon terminus
H0045202cellular_componentsynapse
H0045807biological_processpositive regulation of endocytosis
H0045920biological_processnegative regulation of exocytosis
H0045921biological_processpositive regulation of exocytosis
H0046872molecular_functionmetal ion binding
H0046928biological_processregulation of neurotransmitter secretion
H0048156molecular_functiontau protein binding
H0048168biological_processregulation of neuronal synaptic plasticity
H0048169biological_processregulation of long-term neuronal synaptic plasticity
H0048471cellular_componentperinuclear region of cytoplasm
H0048488biological_processsynaptic vesicle endocytosis
H0048489biological_processsynaptic vesicle transport
H0050729biological_processpositive regulation of inflammatory response
H0050806biological_processpositive regulation of synaptic transmission
H0050808biological_processsynapse organization
H0050812biological_processregulation of acyl-CoA biosynthetic process
H0051219molecular_functionphosphoprotein binding
H0051259biological_processprotein complex oligomerization
H0051262biological_processprotein tetramerization
H0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
H0051402biological_processneuron apoptotic process
H0051583biological_processdopamine uptake involved in synaptic transmission
H0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
H0051612biological_processnegative regulation of serotonin uptake
H0051621biological_processregulation of norepinephrine uptake
H0051622biological_processnegative regulation of norepinephrine uptake
H0055074biological_processcalcium ion homeostasis
H0060079biological_processexcitatory postsynaptic potential
H0060090molecular_functionmolecular adaptor activity
H0060291biological_processlong-term synaptic potentiation
H0060732biological_processpositive regulation of inositol phosphate biosynthetic process
H0060961molecular_functionphospholipase D inhibitor activity
H0061024biological_processmembrane organization
H0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
H0070555biological_processresponse to interleukin-1
H0070840molecular_functiondynein complex binding
H0071280biological_processcellular response to copper ion
H0071872biological_processcellular response to epinephrine stimulus
H0071902biological_processpositive regulation of protein serine/threonine kinase activity
H0097435biological_processsupramolecular fiber organization
H0098794cellular_componentpostsynapse
H0099512cellular_componentsupramolecular fiber
H1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
H1903136molecular_functioncuprous ion binding
H1903284biological_processpositive regulation of glutathione peroxidase activity
H1903285biological_processpositive regulation of hydrogen peroxide catabolic process
H1903421biological_processregulation of synaptic vesicle recycling
H1903426biological_processregulation of reactive oxygen species biosynthetic process
H1904377biological_processpositive regulation of protein localization to cell periphery
H1904715biological_processnegative regulation of chaperone-mediated autophagy
H1905606biological_processregulation of presynapse assembly
H1990000biological_processamyloid fibril formation
H2000377biological_processregulation of reactive oxygen species metabolic process
I0000122biological_processnegative regulation of transcription by RNA polymerase II
I0000149molecular_functionSNARE binding
I0000287molecular_functionmagnesium ion binding
I0000976molecular_functiontranscription cis-regulatory region binding
I0001774biological_processmicroglial cell activation
I0001921biological_processpositive regulation of receptor recycling
I0001956biological_processpositive regulation of neurotransmitter secretion
I0001963biological_processsynaptic transmission, dopaminergic
I0003779molecular_functionactin binding
I0004860molecular_functionprotein kinase inhibitor activity
I0005504molecular_functionfatty acid binding
I0005507molecular_functioncopper ion binding
I0005509molecular_functioncalcium ion binding
I0005515molecular_functionprotein binding
I0005543molecular_functionphospholipid binding
I0005576cellular_componentextracellular region
I0005615cellular_componentextracellular space
I0005634cellular_componentnucleus
I0005737cellular_componentcytoplasm
I0005739cellular_componentmitochondrion
I0005764cellular_componentlysosome
I0005829cellular_componentcytosol
I0005856cellular_componentcytoskeleton
I0005886cellular_componentplasma membrane
I0005938cellular_componentcell cortex
I0006469biological_processnegative regulation of protein kinase activity
I0006631biological_processfatty acid metabolic process
I0006638biological_processneutral lipid metabolic process
I0006644biological_processphospholipid metabolic process
I0006919biological_processactivation of cysteine-type endopeptidase activity involved in apoptotic process
I0007006biological_processmitochondrial membrane organization
I0007268biological_processchemical synaptic transmission
I0007269biological_processneurotransmitter secretion
I0008198molecular_functionferrous iron binding
I0008270molecular_functionzinc ion binding
I0008289molecular_functionlipid binding
I0008344biological_processadult locomotory behavior
I0009410biological_processresponse to xenobiotic stimulus
I0010040biological_processresponse to iron(II) ion
I0010517biological_processregulation of phospholipase activity
I0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
I0014048biological_processregulation of glutamate secretion
I0014059biological_processregulation of dopamine secretion
I0015629cellular_componentactin cytoskeleton
I0016020cellular_componentmembrane
I0016079biological_processsynaptic vesicle exocytosis
I0016082biological_processsynaptic vesicle priming
I0016234cellular_componentinclusion body
I0016491molecular_functionoxidoreductase activity
I0019894molecular_functionkinesin binding
I0022898biological_processregulation of transmembrane transporter activity
I0030424cellular_componentaxon
I0030426cellular_componentgrowth cone
I0030544molecular_functionHsp70 protein binding
I0030672cellular_componentsynaptic vesicle membrane
I0031092cellular_componentplatelet alpha granule membrane
I0031115biological_processnegative regulation of microtubule polymerization
I0031623biological_processreceptor internalization
I0031648biological_processprotein destabilization
I0032026biological_processresponse to magnesium ion
I0032410biological_processnegative regulation of transporter activity
I0032496biological_processresponse to lipopolysaccharide
I0032769biological_processnegative regulation of monooxygenase activity
I0032991cellular_componentprotein-containing complex
I0033138biological_processpositive regulation of peptidyl-serine phosphorylation
I0034341biological_processresponse to type II interferon
I0034599biological_processcellular response to oxidative stress
I0035493biological_processSNARE complex assembly
I0035543biological_processpositive regulation of SNARE complex assembly
I0040012biological_processregulation of locomotion
I0042393molecular_functionhistone binding
I0042416biological_processdopamine biosynthetic process
I0042417biological_processdopamine metabolic process
I0042775biological_processmitochondrial ATP synthesis coupled electron transport
I0042802molecular_functionidentical protein binding
I0042995cellular_componentcell projection
I0043014molecular_functionalpha-tubulin binding
I0043025cellular_componentneuronal cell body
I0043027molecular_functioncysteine-type endopeptidase inhibitor activity involved in apoptotic process
I0043030biological_processregulation of macrophage activation
I0043065biological_processpositive regulation of apoptotic process
I0043066biological_processnegative regulation of apoptotic process
I0043154biological_processnegative regulation of cysteine-type endopeptidase activity involved in apoptotic process
I0043524biological_processnegative regulation of neuron apoptotic process
I0043679cellular_componentaxon terminus
I0045202cellular_componentsynapse
I0045807biological_processpositive regulation of endocytosis
I0045920biological_processnegative regulation of exocytosis
I0045921biological_processpositive regulation of exocytosis
I0046872molecular_functionmetal ion binding
I0046928biological_processregulation of neurotransmitter secretion
I0048156molecular_functiontau protein binding
I0048168biological_processregulation of neuronal synaptic plasticity
I0048169biological_processregulation of long-term neuronal synaptic plasticity
I0048471cellular_componentperinuclear region of cytoplasm
I0048488biological_processsynaptic vesicle endocytosis
I0048489biological_processsynaptic vesicle transport
I0050729biological_processpositive regulation of inflammatory response
I0050806biological_processpositive regulation of synaptic transmission
I0050808biological_processsynapse organization
I0050812biological_processregulation of acyl-CoA biosynthetic process
I0051219molecular_functionphosphoprotein binding
I0051259biological_processprotein complex oligomerization
I0051262biological_processprotein tetramerization
I0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
I0051402biological_processneuron apoptotic process
I0051583biological_processdopamine uptake involved in synaptic transmission
I0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
I0051612biological_processnegative regulation of serotonin uptake
I0051621biological_processregulation of norepinephrine uptake
I0051622biological_processnegative regulation of norepinephrine uptake
I0055074biological_processcalcium ion homeostasis
I0060079biological_processexcitatory postsynaptic potential
I0060090molecular_functionmolecular adaptor activity
I0060291biological_processlong-term synaptic potentiation
I0060732biological_processpositive regulation of inositol phosphate biosynthetic process
I0060961molecular_functionphospholipase D inhibitor activity
I0061024biological_processmembrane organization
I0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
I0070555biological_processresponse to interleukin-1
I0070840molecular_functiondynein complex binding
I0071280biological_processcellular response to copper ion
I0071872biological_processcellular response to epinephrine stimulus
I0071902biological_processpositive regulation of protein serine/threonine kinase activity
I0097435biological_processsupramolecular fiber organization
I0098794cellular_componentpostsynapse
I0099512cellular_componentsupramolecular fiber
I1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
I1903136molecular_functioncuprous ion binding
I1903284biological_processpositive regulation of glutathione peroxidase activity
I1903285biological_processpositive regulation of hydrogen peroxide catabolic process
I1903421biological_processregulation of synaptic vesicle recycling
I1903426biological_processregulation of reactive oxygen species biosynthetic process
I1904377biological_processpositive regulation of protein localization to cell periphery
I1904715biological_processnegative regulation of chaperone-mediated autophagy
I1905606biological_processregulation of presynapse assembly
I1990000biological_processamyloid fibril formation
I2000377biological_processregulation of reactive oxygen species metabolic process
J0000122biological_processnegative regulation of transcription by RNA polymerase II
J0000149molecular_functionSNARE binding
J0000287molecular_functionmagnesium ion binding
J0000976molecular_functiontranscription cis-regulatory region binding
J0001774biological_processmicroglial cell activation
J0001921biological_processpositive regulation of receptor recycling
J0001956biological_processpositive regulation of neurotransmitter secretion
J0001963biological_processsynaptic transmission, dopaminergic
J0003779molecular_functionactin binding
J0004860molecular_functionprotein kinase inhibitor activity
J0005504molecular_functionfatty acid binding
J0005507molecular_functioncopper ion binding
J0005509molecular_functioncalcium ion binding
J0005515molecular_functionprotein binding
J0005543molecular_functionphospholipid binding
J0005576cellular_componentextracellular region
J0005615cellular_componentextracellular space
J0005634cellular_componentnucleus
J0005737cellular_componentcytoplasm
J0005739cellular_componentmitochondrion
J0005764cellular_componentlysosome
J0005829cellular_componentcytosol
J0005856cellular_componentcytoskeleton
J0005886cellular_componentplasma membrane
J0005938cellular_componentcell cortex
J0006469biological_processnegative regulation of protein kinase activity
J0006631biological_processfatty acid metabolic process
J0006638biological_processneutral lipid metabolic process
J0006644biological_processphospholipid metabolic process
J0006919biological_processactivation of cysteine-type endopeptidase activity involved in apoptotic process
J0007006biological_processmitochondrial membrane organization
J0007268biological_processchemical synaptic transmission
J0007269biological_processneurotransmitter secretion
J0008198molecular_functionferrous iron binding
J0008270molecular_functionzinc ion binding
J0008289molecular_functionlipid binding
J0008344biological_processadult locomotory behavior
J0009410biological_processresponse to xenobiotic stimulus
J0010040biological_processresponse to iron(II) ion
J0010517biological_processregulation of phospholipase activity
J0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
J0014048biological_processregulation of glutamate secretion
J0014059biological_processregulation of dopamine secretion
J0015629cellular_componentactin cytoskeleton
J0016020cellular_componentmembrane
J0016079biological_processsynaptic vesicle exocytosis
J0016082biological_processsynaptic vesicle priming
J0016234cellular_componentinclusion body
J0016491molecular_functionoxidoreductase activity
J0019894molecular_functionkinesin binding
J0022898biological_processregulation of transmembrane transporter activity
J0030424cellular_componentaxon
J0030426cellular_componentgrowth cone
J0030544molecular_functionHsp70 protein binding
J0030672cellular_componentsynaptic vesicle membrane
J0031092cellular_componentplatelet alpha granule membrane
J0031115biological_processnegative regulation of microtubule polymerization
J0031623biological_processreceptor internalization
J0031648biological_processprotein destabilization
J0032026biological_processresponse to magnesium ion
J0032410biological_processnegative regulation of transporter activity
J0032496biological_processresponse to lipopolysaccharide
J0032769biological_processnegative regulation of monooxygenase activity
J0032991cellular_componentprotein-containing complex
J0033138biological_processpositive regulation of peptidyl-serine phosphorylation
J0034341biological_processresponse to type II interferon
J0034599biological_processcellular response to oxidative stress
J0035493biological_processSNARE complex assembly
J0035543biological_processpositive regulation of SNARE complex assembly
J0040012biological_processregulation of locomotion
J0042393molecular_functionhistone binding
J0042416biological_processdopamine biosynthetic process
J0042417biological_processdopamine metabolic process
J0042775biological_processmitochondrial ATP synthesis coupled electron transport
J0042802molecular_functionidentical protein binding
J0042995cellular_componentcell projection
J0043014molecular_functionalpha-tubulin binding
J0043025cellular_componentneuronal cell body
J0043027molecular_functioncysteine-type endopeptidase inhibitor activity involved in apoptotic process
J0043030biological_processregulation of macrophage activation
J0043065biological_processpositive regulation of apoptotic process
J0043066biological_processnegative regulation of apoptotic process
J0043154biological_processnegative regulation of cysteine-type endopeptidase activity involved in apoptotic process
J0043524biological_processnegative regulation of neuron apoptotic process
J0043679cellular_componentaxon terminus
J0045202cellular_componentsynapse
J0045807biological_processpositive regulation of endocytosis
J0045920biological_processnegative regulation of exocytosis
J0045921biological_processpositive regulation of exocytosis
J0046872molecular_functionmetal ion binding
J0046928biological_processregulation of neurotransmitter secretion
J0048156molecular_functiontau protein binding
J0048168biological_processregulation of neuronal synaptic plasticity
J0048169biological_processregulation of long-term neuronal synaptic plasticity
J0048471cellular_componentperinuclear region of cytoplasm
J0048488biological_processsynaptic vesicle endocytosis
J0048489biological_processsynaptic vesicle transport
J0050729biological_processpositive regulation of inflammatory response
J0050806biological_processpositive regulation of synaptic transmission
J0050808biological_processsynapse organization
J0050812biological_processregulation of acyl-CoA biosynthetic process
J0051219molecular_functionphosphoprotein binding
J0051259biological_processprotein complex oligomerization
J0051262biological_processprotein tetramerization
J0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
J0051402biological_processneuron apoptotic process
J0051583biological_processdopamine uptake involved in synaptic transmission
J0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
J0051612biological_processnegative regulation of serotonin uptake
J0051621biological_processregulation of norepinephrine uptake
J0051622biological_processnegative regulation of norepinephrine uptake
J0055074biological_processcalcium ion homeostasis
J0060079biological_processexcitatory postsynaptic potential
J0060090molecular_functionmolecular adaptor activity
J0060291biological_processlong-term synaptic potentiation
J0060732biological_processpositive regulation of inositol phosphate biosynthetic process
J0060961molecular_functionphospholipase D inhibitor activity
J0061024biological_processmembrane organization
J0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
J0070555biological_processresponse to interleukin-1
J0070840molecular_functiondynein complex binding
J0071280biological_processcellular response to copper ion
J0071872biological_processcellular response to epinephrine stimulus
J0071902biological_processpositive regulation of protein serine/threonine kinase activity
J0097435biological_processsupramolecular fiber organization
J0098794cellular_componentpostsynapse
J0099512cellular_componentsupramolecular fiber
J1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
J1903136molecular_functioncuprous ion binding
J1903284biological_processpositive regulation of glutathione peroxidase activity
J1903285biological_processpositive regulation of hydrogen peroxide catabolic process
J1903421biological_processregulation of synaptic vesicle recycling
J1903426biological_processregulation of reactive oxygen species biosynthetic process
J1904377biological_processpositive regulation of protein localization to cell periphery
J1904715biological_processnegative regulation of chaperone-mediated autophagy
J1905606biological_processregulation of presynapse assembly
J1990000biological_processamyloid fibril formation
J2000377biological_processregulation of reactive oxygen species metabolic process
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues20
DetailsBINDING: BINDING => ECO:0000305
ChainResidueDetails
AASP2
EHIS50
FASP2
FHIS50
GASP2
GHIS50
HASP2
HHIS50
IASP2
IHIS50
JASP2
AHIS50
JHIS50
BASP2
BHIS50
CASP2
CHIS50
DASP2
DHIS50
EASP2

site_idSWS_FT_FI2
Number of Residues10
DetailsMOD_RES: N-acetylmethionine => ECO:0000269|PubMed:22407793
ChainResidueDetails
AMET1
JMET1
BMET1
CMET1
DMET1
EMET1
FMET1
GMET1
HMET1
IMET1

site_idSWS_FT_FI3
Number of Residues10
DetailsMOD_RES: Phosphoserine => ECO:0000269|PubMed:10617630
ChainResidueDetails
ASER87
JSER87
BSER87
CSER87
DSER87
ESER87
FSER87
GSER87
HSER87
ISER87

site_idSWS_FT_FI4
Number of Residues10
DetailsMOD_RES: Phosphotyrosine; by FYN => ECO:0000269|PubMed:11162638, ECO:0000269|PubMed:12893833
ChainResidueDetails
ATYR125
JTYR125
BTYR125
CTYR125
DTYR125
ETYR125
FTYR125
GTYR125
HTYR125
ITYR125

site_idSWS_FT_FI5
Number of Residues10
DetailsMOD_RES: Phosphoserine; by BARK1, PLK2, CK2, CK1 and GRK5 => ECO:0000269|PubMed:10617630, ECO:0000269|PubMed:11813001, ECO:0000269|PubMed:24936070
ChainResidueDetails
ASER129
JSER129
BSER129
CSER129
DSER129
ESER129
FSER129
GSER129
HSER129
ISER129

226707

PDB entries from 2024-10-30

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