8RLM

TRIF Oligomerisation

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002224	biological_process	toll-like receptor signaling pathway
A	0002281	biological_process	macrophage activation involved in immune response
A	0002376	biological_process	immune system process
A	0002735	biological_process	positive regulation of myeloid dendritic cell cytokine production
A	0002756	biological_process	MyD88-independent toll-like receptor signaling pathway
A	0005515	molecular_function	protein binding
A	0005739	cellular_component	mitochondrion
A	0005768	cellular_component	endosome
A	0005769	cellular_component	early endosome
A	0005776	cellular_component	autophagosome
A	0005829	cellular_component	cytosol
A	0006809	biological_process	nitric oxide biosynthetic process
A	0006915	biological_process	apoptotic process
A	0006954	biological_process	inflammatory response
A	0007166	biological_process	cell surface receptor signaling pathway
A	0010008	cellular_component	endosome membrane
A	0010508	biological_process	positive regulation of autophagy
A	0010628	biological_process	positive regulation of gene expression
A	0019901	molecular_function	protein kinase binding
A	0030890	biological_process	positive regulation of B cell proliferation
A	0031398	biological_process	positive regulation of protein ubiquitination
A	0031410	cellular_component	cytoplasmic vesicle
A	0031663	biological_process	lipopolysaccharide-mediated signaling pathway
A	0032481	biological_process	positive regulation of type I interferon production
A	0032496	biological_process	response to lipopolysaccharide
A	0032722	biological_process	positive regulation of chemokine production
A	0032728	biological_process	positive regulation of interferon-beta production
A	0032755	biological_process	positive regulation of interleukin-6 production
A	0032760	biological_process	positive regulation of tumor necrosis factor production
A	0032816	biological_process	positive regulation of natural killer cell activation
A	0034138	biological_process	toll-like receptor 3 signaling pathway
A	0034142	biological_process	toll-like receptor 4 signaling pathway
A	0035591	molecular_function	signaling adaptor activity
A	0035666	biological_process	TRIF-dependent toll-like receptor signaling pathway
A	0042100	biological_process	B cell proliferation
A	0042113	biological_process	B cell activation
A	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
A	0043254	biological_process	regulation of protein-containing complex assembly
A	0043330	biological_process	response to exogenous dsRNA
A	0045087	biological_process	innate immune response
A	0045429	biological_process	positive regulation of nitric oxide biosynthetic process
A	0050871	biological_process	positive regulation of B cell activation
A	0051607	biological_process	defense response to virus
A	0060090	molecular_function	molecular adaptor activity
A	0060907	biological_process	positive regulation of macrophage cytokine production
A	0071222	biological_process	cellular response to lipopolysaccharide
A	0097190	biological_process	apoptotic signaling pathway
A	0097342	cellular_component	ripoptosome
A	0140052	biological_process	cellular response to oxidised low-density lipoprotein particle stimulus
A	1900017	biological_process	positive regulation of cytokine production involved in inflammatory response
B	0002224	biological_process	toll-like receptor signaling pathway
B	0002281	biological_process	macrophage activation involved in immune response
B	0002376	biological_process	immune system process
B	0002735	biological_process	positive regulation of myeloid dendritic cell cytokine production
B	0002756	biological_process	MyD88-independent toll-like receptor signaling pathway
B	0005515	molecular_function	protein binding
B	0005739	cellular_component	mitochondrion
B	0005768	cellular_component	endosome
B	0005769	cellular_component	early endosome
B	0005776	cellular_component	autophagosome
B	0005829	cellular_component	cytosol
B	0006809	biological_process	nitric oxide biosynthetic process
B	0006915	biological_process	apoptotic process
B	0006954	biological_process	inflammatory response
B	0007166	biological_process	cell surface receptor signaling pathway
B	0010008	cellular_component	endosome membrane
B	0010508	biological_process	positive regulation of autophagy
B	0010628	biological_process	positive regulation of gene expression
B	0019901	molecular_function	protein kinase binding
B	0030890	biological_process	positive regulation of B cell proliferation
B	0031398	biological_process	positive regulation of protein ubiquitination
B	0031410	cellular_component	cytoplasmic vesicle
B	0031663	biological_process	lipopolysaccharide-mediated signaling pathway
B	0032481	biological_process	positive regulation of type I interferon production
B	0032496	biological_process	response to lipopolysaccharide
B	0032722	biological_process	positive regulation of chemokine production
B	0032728	biological_process	positive regulation of interferon-beta production
B	0032755	biological_process	positive regulation of interleukin-6 production
B	0032760	biological_process	positive regulation of tumor necrosis factor production
B	0032816	biological_process	positive regulation of natural killer cell activation
B	0034138	biological_process	toll-like receptor 3 signaling pathway
B	0034142	biological_process	toll-like receptor 4 signaling pathway
B	0035591	molecular_function	signaling adaptor activity
B	0035666	biological_process	TRIF-dependent toll-like receptor signaling pathway
B	0042100	biological_process	B cell proliferation
B	0042113	biological_process	B cell activation
B	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
B	0043254	biological_process	regulation of protein-containing complex assembly
B	0043330	biological_process	response to exogenous dsRNA
B	0045087	biological_process	innate immune response
B	0045429	biological_process	positive regulation of nitric oxide biosynthetic process
B	0050871	biological_process	positive regulation of B cell activation
B	0051607	biological_process	defense response to virus
B	0060090	molecular_function	molecular adaptor activity
B	0060907	biological_process	positive regulation of macrophage cytokine production
B	0071222	biological_process	cellular response to lipopolysaccharide
B	0097190	biological_process	apoptotic signaling pathway
B	0097342	cellular_component	ripoptosome
B	0140052	biological_process	cellular response to oxidised low-density lipoprotein particle stimulus
B	1900017	biological_process	positive regulation of cytokine production involved in inflammatory response
C	0002224	biological_process	toll-like receptor signaling pathway
C	0002281	biological_process	macrophage activation involved in immune response
C	0002376	biological_process	immune system process
C	0002735	biological_process	positive regulation of myeloid dendritic cell cytokine production
C	0002756	biological_process	MyD88-independent toll-like receptor signaling pathway
C	0005515	molecular_function	protein binding
C	0005739	cellular_component	mitochondrion
C	0005768	cellular_component	endosome
C	0005769	cellular_component	early endosome
C	0005776	cellular_component	autophagosome
C	0005829	cellular_component	cytosol
C	0006809	biological_process	nitric oxide biosynthetic process
C	0006915	biological_process	apoptotic process
C	0006954	biological_process	inflammatory response
C	0007166	biological_process	cell surface receptor signaling pathway
C	0010008	cellular_component	endosome membrane
C	0010508	biological_process	positive regulation of autophagy
C	0010628	biological_process	positive regulation of gene expression
C	0019901	molecular_function	protein kinase binding
C	0030890	biological_process	positive regulation of B cell proliferation
C	0031398	biological_process	positive regulation of protein ubiquitination
C	0031410	cellular_component	cytoplasmic vesicle
C	0031663	biological_process	lipopolysaccharide-mediated signaling pathway
C	0032481	biological_process	positive regulation of type I interferon production
C	0032496	biological_process	response to lipopolysaccharide
C	0032722	biological_process	positive regulation of chemokine production
C	0032728	biological_process	positive regulation of interferon-beta production
C	0032755	biological_process	positive regulation of interleukin-6 production
C	0032760	biological_process	positive regulation of tumor necrosis factor production
C	0032816	biological_process	positive regulation of natural killer cell activation
C	0034138	biological_process	toll-like receptor 3 signaling pathway
C	0034142	biological_process	toll-like receptor 4 signaling pathway
C	0035591	molecular_function	signaling adaptor activity
C	0035666	biological_process	TRIF-dependent toll-like receptor signaling pathway
C	0042100	biological_process	B cell proliferation
C	0042113	biological_process	B cell activation
C	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
C	0043254	biological_process	regulation of protein-containing complex assembly
C	0043330	biological_process	response to exogenous dsRNA
C	0045087	biological_process	innate immune response
C	0045429	biological_process	positive regulation of nitric oxide biosynthetic process
C	0050871	biological_process	positive regulation of B cell activation
C	0051607	biological_process	defense response to virus
C	0060090	molecular_function	molecular adaptor activity
C	0060907	biological_process	positive regulation of macrophage cytokine production
C	0071222	biological_process	cellular response to lipopolysaccharide
C	0097190	biological_process	apoptotic signaling pathway
C	0097342	cellular_component	ripoptosome
C	0140052	biological_process	cellular response to oxidised low-density lipoprotein particle stimulus
C	1900017	biological_process	positive regulation of cytokine production involved in inflammatory response
D	0002224	biological_process	toll-like receptor signaling pathway
D	0002281	biological_process	macrophage activation involved in immune response
D	0002376	biological_process	immune system process
D	0002735	biological_process	positive regulation of myeloid dendritic cell cytokine production
D	0002756	biological_process	MyD88-independent toll-like receptor signaling pathway
D	0005515	molecular_function	protein binding
D	0005739	cellular_component	mitochondrion
D	0005768	cellular_component	endosome
D	0005769	cellular_component	early endosome
D	0005776	cellular_component	autophagosome
D	0005829	cellular_component	cytosol
D	0006809	biological_process	nitric oxide biosynthetic process
D	0006915	biological_process	apoptotic process
D	0006954	biological_process	inflammatory response
D	0007166	biological_process	cell surface receptor signaling pathway
D	0010008	cellular_component	endosome membrane
D	0010508	biological_process	positive regulation of autophagy
D	0010628	biological_process	positive regulation of gene expression
D	0019901	molecular_function	protein kinase binding
D	0030890	biological_process	positive regulation of B cell proliferation
D	0031398	biological_process	positive regulation of protein ubiquitination
D	0031410	cellular_component	cytoplasmic vesicle
D	0031663	biological_process	lipopolysaccharide-mediated signaling pathway
D	0032481	biological_process	positive regulation of type I interferon production
D	0032496	biological_process	response to lipopolysaccharide
D	0032722	biological_process	positive regulation of chemokine production
D	0032728	biological_process	positive regulation of interferon-beta production
D	0032755	biological_process	positive regulation of interleukin-6 production
D	0032760	biological_process	positive regulation of tumor necrosis factor production
D	0032816	biological_process	positive regulation of natural killer cell activation
D	0034138	biological_process	toll-like receptor 3 signaling pathway
D	0034142	biological_process	toll-like receptor 4 signaling pathway
D	0035591	molecular_function	signaling adaptor activity
D	0035666	biological_process	TRIF-dependent toll-like receptor signaling pathway
D	0042100	biological_process	B cell proliferation
D	0042113	biological_process	B cell activation
D	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
D	0043254	biological_process	regulation of protein-containing complex assembly
D	0043330	biological_process	response to exogenous dsRNA
D	0045087	biological_process	innate immune response
D	0045429	biological_process	positive regulation of nitric oxide biosynthetic process
D	0050871	biological_process	positive regulation of B cell activation
D	0051607	biological_process	defense response to virus
D	0060090	molecular_function	molecular adaptor activity
D	0060907	biological_process	positive regulation of macrophage cytokine production
D	0071222	biological_process	cellular response to lipopolysaccharide
D	0097190	biological_process	apoptotic signaling pathway
D	0097342	cellular_component	ripoptosome
D	0140052	biological_process	cellular response to oxidised low-density lipoprotein particle stimulus
D	1900017	biological_process	positive regulation of cytokine production involved in inflammatory response
E	0002224	biological_process	toll-like receptor signaling pathway
E	0002281	biological_process	macrophage activation involved in immune response
E	0002376	biological_process	immune system process
E	0002735	biological_process	positive regulation of myeloid dendritic cell cytokine production
E	0002756	biological_process	MyD88-independent toll-like receptor signaling pathway
E	0005515	molecular_function	protein binding
E	0005739	cellular_component	mitochondrion
E	0005768	cellular_component	endosome
E	0005769	cellular_component	early endosome
E	0005776	cellular_component	autophagosome
E	0005829	cellular_component	cytosol
E	0006809	biological_process	nitric oxide biosynthetic process
E	0006915	biological_process	apoptotic process
E	0006954	biological_process	inflammatory response
E	0007166	biological_process	cell surface receptor signaling pathway
E	0010008	cellular_component	endosome membrane
E	0010508	biological_process	positive regulation of autophagy
E	0010628	biological_process	positive regulation of gene expression
E	0019901	molecular_function	protein kinase binding
E	0030890	biological_process	positive regulation of B cell proliferation
E	0031398	biological_process	positive regulation of protein ubiquitination
E	0031410	cellular_component	cytoplasmic vesicle
E	0031663	biological_process	lipopolysaccharide-mediated signaling pathway
E	0032481	biological_process	positive regulation of type I interferon production
E	0032496	biological_process	response to lipopolysaccharide
E	0032722	biological_process	positive regulation of chemokine production
E	0032728	biological_process	positive regulation of interferon-beta production
E	0032755	biological_process	positive regulation of interleukin-6 production
E	0032760	biological_process	positive regulation of tumor necrosis factor production
E	0032816	biological_process	positive regulation of natural killer cell activation
E	0034138	biological_process	toll-like receptor 3 signaling pathway
E	0034142	biological_process	toll-like receptor 4 signaling pathway
E	0035591	molecular_function	signaling adaptor activity
E	0035666	biological_process	TRIF-dependent toll-like receptor signaling pathway
E	0042100	biological_process	B cell proliferation
E	0042113	biological_process	B cell activation
E	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
E	0043254	biological_process	regulation of protein-containing complex assembly
E	0043330	biological_process	response to exogenous dsRNA
E	0045087	biological_process	innate immune response
E	0045429	biological_process	positive regulation of nitric oxide biosynthetic process
E	0050871	biological_process	positive regulation of B cell activation
E	0051607	biological_process	defense response to virus
E	0060090	molecular_function	molecular adaptor activity
E	0060907	biological_process	positive regulation of macrophage cytokine production
E	0071222	biological_process	cellular response to lipopolysaccharide
E	0097190	biological_process	apoptotic signaling pathway
E	0097342	cellular_component	ripoptosome
E	0140052	biological_process	cellular response to oxidised low-density lipoprotein particle stimulus
E	1900017	biological_process	positive regulation of cytokine production involved in inflammatory response
F	0002224	biological_process	toll-like receptor signaling pathway
F	0002281	biological_process	macrophage activation involved in immune response
F	0002376	biological_process	immune system process
F	0002735	biological_process	positive regulation of myeloid dendritic cell cytokine production
F	0002756	biological_process	MyD88-independent toll-like receptor signaling pathway
F	0005515	molecular_function	protein binding
F	0005739	cellular_component	mitochondrion
F	0005768	cellular_component	endosome
F	0005769	cellular_component	early endosome
F	0005776	cellular_component	autophagosome
F	0005829	cellular_component	cytosol
F	0006809	biological_process	nitric oxide biosynthetic process
F	0006915	biological_process	apoptotic process
F	0006954	biological_process	inflammatory response
F	0007166	biological_process	cell surface receptor signaling pathway
F	0010008	cellular_component	endosome membrane
F	0010508	biological_process	positive regulation of autophagy
F	0010628	biological_process	positive regulation of gene expression
F	0019901	molecular_function	protein kinase binding
F	0030890	biological_process	positive regulation of B cell proliferation
F	0031398	biological_process	positive regulation of protein ubiquitination
F	0031410	cellular_component	cytoplasmic vesicle
F	0031663	biological_process	lipopolysaccharide-mediated signaling pathway
F	0032481	biological_process	positive regulation of type I interferon production
F	0032496	biological_process	response to lipopolysaccharide
F	0032722	biological_process	positive regulation of chemokine production
F	0032728	biological_process	positive regulation of interferon-beta production
F	0032755	biological_process	positive regulation of interleukin-6 production
F	0032760	biological_process	positive regulation of tumor necrosis factor production
F	0032816	biological_process	positive regulation of natural killer cell activation
F	0034138	biological_process	toll-like receptor 3 signaling pathway
F	0034142	biological_process	toll-like receptor 4 signaling pathway
F	0035591	molecular_function	signaling adaptor activity
F	0035666	biological_process	TRIF-dependent toll-like receptor signaling pathway
F	0042100	biological_process	B cell proliferation
F	0042113	biological_process	B cell activation
F	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
F	0043254	biological_process	regulation of protein-containing complex assembly
F	0043330	biological_process	response to exogenous dsRNA
F	0045087	biological_process	innate immune response
F	0045429	biological_process	positive regulation of nitric oxide biosynthetic process
F	0050871	biological_process	positive regulation of B cell activation
F	0051607	biological_process	defense response to virus
F	0060090	molecular_function	molecular adaptor activity
F	0060907	biological_process	positive regulation of macrophage cytokine production
F	0071222	biological_process	cellular response to lipopolysaccharide
F	0097190	biological_process	apoptotic signaling pathway
F	0097342	cellular_component	ripoptosome
F	0140052	biological_process	cellular response to oxidised low-density lipoprotein particle stimulus
F	1900017	biological_process	positive regulation of cytokine production involved in inflammatory response

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Site: {"description":"(Microbial infection) Cleavage; by viral HAV 3CD","evidences":[{"source":"PubMed","id":"21931545","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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