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8R3O

Transketolase from Haemophilus influenzae in complex with thiamin pyrophosphate

Functional Information from GO Data
ChainGOidnamespacecontents
A0004802molecular_functiontransketolase activity
A0005829cellular_componentcytosol
A0006098biological_processpentose-phosphate shunt
A0009052biological_processpentose-phosphate shunt, non-oxidative branch
A0016740molecular_functiontransferase activity
A0046872molecular_functionmetal ion binding
B0004802molecular_functiontransketolase activity
B0005829cellular_componentcytosol
B0006098biological_processpentose-phosphate shunt
B0009052biological_processpentose-phosphate shunt, non-oxidative branch
B0016740molecular_functiontransferase activity
B0046872molecular_functionmetal ion binding
C0004802molecular_functiontransketolase activity
C0005829cellular_componentcytosol
C0006098biological_processpentose-phosphate shunt
C0009052biological_processpentose-phosphate shunt, non-oxidative branch
C0016740molecular_functiontransferase activity
C0046872molecular_functionmetal ion binding
D0004802molecular_functiontransketolase activity
D0005829cellular_componentcytosol
D0006098biological_processpentose-phosphate shunt
D0009052biological_processpentose-phosphate shunt, non-oxidative branch
D0016740molecular_functiontransferase activity
D0046872molecular_functionmetal ion binding
Functional Information from PROSITE/UniProt
site_idPS00801
Number of Residues21
DetailsTRANSKETOLASE_1 Transketolase signature 1. RvlaMDsvqkakSGHPGapMG
ChainResidueDetails
AARG12-GLY32

site_idPS00802
Number of Residues17
DetailsTRANSKETOLASE_2 Transketolase signature 2. GEDGPTHqPVEqtAslR
ChainResidueDetails
AGLY469-ARG485

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsActive site: {"description":"Proton donor","evidences":[{"evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues60
DetailsBinding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues8
DetailsSite: {"description":"Important for catalytic activity","evidences":[{"evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

239492

PDB entries from 2025-07-30

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