8QXY

Xylanase from Bacillus circulans mutant E78Q bound to xylotriose

Functional Information from PROSITE/UniProt

site_id	PS00777
Number of Residues	12
Details	GH11_2 Glycosyl hydrolases family 11 (GH11) active site signature 2. MatEGYQSSGsS

Chain	Residue	Details
A	MET169-SER180

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Nucleophile => ECO:0000255|PROSITE-ProRule:PRU10062, ECO:0000269|PubMed:8019418

Chain	Residue	Details
A	GLN78
B	GLN78

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site_id	SWS_FT_FI2
Number of Residues	2
Details	ACT_SITE: Proton donor => ECO:0000255|PROSITE-ProRule:PRU10063, ECO:0000269|PubMed:8019418

Chain	Residue	Details
A	GLU172
B	GLU172

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues	5
Details	M-CSA 432

Chain	Residue	Details
A	ASN35	modifies pKa
A	TYR69	electrostatic destabiliser
A	GLN78	covalent catalysis, proton shuttle (general acid/base)
A	TYR80	modifies pKa
A	GLU172	proton shuttle (general acid/base)

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site_id	MCSA2
Number of Residues	5
Details	M-CSA 432

Chain	Residue	Details
B	ASN35	modifies pKa
B	TYR69	electrostatic destabiliser
B	GLN78	covalent catalysis, proton shuttle (general acid/base)
B	TYR80	modifies pKa
B	GLU172	proton shuttle (general acid/base)

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