8QVP

Cryo-EM structure of human islet amyloid polypeptide (hIAPP) mutant S29P, polymorph 1

Functional Information from GO Data

Chain	GOid	namespace	contents
H	0005179	molecular_function	hormone activity
H	0005576	cellular_component	extracellular region
I	0005179	molecular_function	hormone activity
I	0005576	cellular_component	extracellular region
J	0005179	molecular_function	hormone activity
J	0005576	cellular_component	extracellular region
K	0005179	molecular_function	hormone activity
K	0005576	cellular_component	extracellular region
L	0005179	molecular_function	hormone activity
L	0005576	cellular_component	extracellular region
M	0005179	molecular_function	hormone activity
M	0005576	cellular_component	extracellular region
N	0005179	molecular_function	hormone activity
N	0005576	cellular_component	extracellular region
O	0005179	molecular_function	hormone activity
O	0005576	cellular_component	extracellular region
P	0005179	molecular_function	hormone activity
P	0005576	cellular_component	extracellular region
Q	0005179	molecular_function	hormone activity
Q	0005576	cellular_component	extracellular region

Functional Information from PROSITE/UniProt

site_id	PS00258
Number of Residues	15
Details	CALCITONIN Calcitonin / CGRP / IAPP family signature. CNT.ATCAtqrLanfL

Chain	Residue	Details
H	CYS2-LEU16

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	10
Details	Modified residue: {"description":"Tyrosine amide","evidences":[{"source":"PubMed","id":"2651160","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"3053705","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---