8QST

Cryo-EM structure of the glucose-specific PTS transporter IICB from E. coli in the inward- and outward-facing conformation

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005886	cellular_component	plasma membrane
A	0006355	biological_process	regulation of DNA-templated transcription
A	0008982	molecular_function	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A	0009401	biological_process	phosphoenolpyruvate-dependent sugar phosphotransferase system
A	0016020	cellular_component	membrane
A	0016301	molecular_function	kinase activity
A	0016740	molecular_function	transferase activity
A	0055056	molecular_function	D-glucose transmembrane transporter activity
A	0090564	molecular_function	protein-phosphocysteine-glucose phosphotransferase system transporter activity
A	0098708	biological_process	D-glucose import across plasma membrane
A	1904659	biological_process	D-glucose transmembrane transport
B	0005515	molecular_function	protein binding
B	0005886	cellular_component	plasma membrane
B	0006355	biological_process	regulation of DNA-templated transcription
B	0008982	molecular_function	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B	0009401	biological_process	phosphoenolpyruvate-dependent sugar phosphotransferase system
B	0016020	cellular_component	membrane
B	0016301	molecular_function	kinase activity
B	0016740	molecular_function	transferase activity
B	0055056	molecular_function	D-glucose transmembrane transporter activity
B	0090564	molecular_function	protein-phosphocysteine-glucose phosphotransferase system transporter activity
B	0098708	biological_process	D-glucose import across plasma membrane
B	1904659	biological_process	D-glucose transmembrane transport

Functional Information from PROSITE/UniProt

site_id	PS01035
Number of Residues	18
Details	PTS_EIIB_TYPE_1_CYS PTS EIIB domains cysteine phosphorylation site signature. NItnldaCiTRLrVsVaD

Chain	Residue	Details
A	ASN414-ASP431

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	400
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PROSITE-ProRule","id":"PRU00426","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	146
Details	Topological domain: {"description":"Periplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	140
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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