8QO9

Cryo-EM structure of a human spliceosomal B complex protomer

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
21	0000243	cellular_component	commitment complex
21	0000245	biological_process	spliceosomal complex assembly
21	0000387	biological_process	spliceosomal snRNP assembly
21	0000398	biological_process	mRNA splicing, via spliceosome
21	0003723	molecular_function	RNA binding
21	0005515	molecular_function	protein binding
21	0005634	cellular_component	nucleus
21	0005654	cellular_component	nucleoplasm
21	0005681	cellular_component	spliceosomal complex
21	0005682	cellular_component	U5 snRNP
21	0005684	cellular_component	U2-type spliceosomal complex
21	0005685	cellular_component	U1 snRNP
21	0005686	cellular_component	U2 snRNP
21	0005687	cellular_component	U4 snRNP
21	0005689	cellular_component	U12-type spliceosomal complex
21	0005737	cellular_component	cytoplasm
21	0005829	cellular_component	cytosol
21	0006396	biological_process	RNA processing
21	0006397	biological_process	mRNA processing
21	0008380	biological_process	RNA splicing
21	0030532	cellular_component	small nuclear ribonucleoprotein complex
21	0034709	cellular_component	methylosome
21	0034715	cellular_component	pICln-Sm protein complex
21	0034719	cellular_component	SMN-Sm protein complex
21	0036261	biological_process	7-methylguanosine cap hypermethylation
21	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
21	0071005	cellular_component	U2-type precatalytic spliceosome
21	0071007	cellular_component	U2-type catalytic step 2 spliceosome
21	0071011	cellular_component	precatalytic spliceosome
21	0071013	cellular_component	catalytic step 2 spliceosome
21	0097526	cellular_component	spliceosomal tri-snRNP complex
21	1903241	biological_process	U2-type prespliceosome assembly
21	1990446	molecular_function	U1 snRNP binding
22	0000245	biological_process	spliceosomal complex assembly
22	0000387	biological_process	spliceosomal snRNP assembly
22	0000398	biological_process	mRNA splicing, via spliceosome
22	0003723	molecular_function	RNA binding
22	0005515	molecular_function	protein binding
22	0005634	cellular_component	nucleus
22	0005654	cellular_component	nucleoplasm
22	0005681	cellular_component	spliceosomal complex
22	0005682	cellular_component	U5 snRNP
22	0005684	cellular_component	U2-type spliceosomal complex
22	0005685	cellular_component	U1 snRNP
22	0005686	cellular_component	U2 snRNP
22	0005687	cellular_component	U4 snRNP
22	0005689	cellular_component	U12-type spliceosomal complex
22	0005737	cellular_component	cytoplasm
22	0005829	cellular_component	cytosol
22	0006397	biological_process	mRNA processing
22	0008380	biological_process	RNA splicing
22	0030532	cellular_component	small nuclear ribonucleoprotein complex
22	0034709	cellular_component	methylosome
22	0034715	cellular_component	pICln-Sm protein complex
22	0034719	cellular_component	SMN-Sm protein complex
22	0036261	biological_process	7-methylguanosine cap hypermethylation
22	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
22	0070062	cellular_component	extracellular exosome
22	0071005	cellular_component	U2-type precatalytic spliceosome
22	0071007	cellular_component	U2-type catalytic step 2 spliceosome
22	0071011	cellular_component	precatalytic spliceosome
22	0071013	cellular_component	catalytic step 2 spliceosome
22	1903241	biological_process	U2-type prespliceosome assembly
23	0000243	cellular_component	commitment complex
23	0000387	biological_process	spliceosomal snRNP assembly
23	0000398	biological_process	mRNA splicing, via spliceosome
23	0003723	molecular_function	RNA binding
23	0005515	molecular_function	protein binding
23	0005634	cellular_component	nucleus
23	0005654	cellular_component	nucleoplasm
23	0005681	cellular_component	spliceosomal complex
23	0005682	cellular_component	U5 snRNP
23	0005683	cellular_component	U7 snRNP
23	0005684	cellular_component	U2-type spliceosomal complex
23	0005685	cellular_component	U1 snRNP
23	0005686	cellular_component	U2 snRNP
23	0005687	cellular_component	U4 snRNP
23	0005689	cellular_component	U12-type spliceosomal complex
23	0005697	cellular_component	telomerase holoenzyme complex
23	0005737	cellular_component	cytoplasm
23	0005829	cellular_component	cytosol
23	0006396	biological_process	RNA processing
23	0006397	biological_process	mRNA processing
23	0006479	biological_process	protein methylation
23	0008380	biological_process	RNA splicing
23	0016604	cellular_component	nuclear body
23	0019899	molecular_function	enzyme binding
23	0030532	cellular_component	small nuclear ribonucleoprotein complex
23	0034709	cellular_component	methylosome
23	0034715	cellular_component	pICln-Sm protein complex
23	0034719	cellular_component	SMN-Sm protein complex
23	0036261	biological_process	7-methylguanosine cap hypermethylation
23	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
23	0070034	molecular_function	telomerase RNA binding
23	0071005	cellular_component	U2-type precatalytic spliceosome
23	0071007	cellular_component	U2-type catalytic step 2 spliceosome
23	0071011	cellular_component	precatalytic spliceosome
23	0071013	cellular_component	catalytic step 2 spliceosome
23	0071208	molecular_function	histone pre-mRNA DCP binding
23	0071209	molecular_function	U7 snRNA binding
23	0097526	cellular_component	spliceosomal tri-snRNP complex
23	1903241	biological_process	U2-type prespliceosome assembly
2A	0000398	biological_process	mRNA splicing, via spliceosome
2A	0003723	molecular_function	RNA binding
2A	0005515	molecular_function	protein binding
2A	0005634	cellular_component	nucleus
2A	0005654	cellular_component	nucleoplasm
2A	0005681	cellular_component	spliceosomal complex
2A	0005684	cellular_component	U2-type spliceosomal complex
2A	0005686	cellular_component	U2 snRNP
2A	0006397	biological_process	mRNA processing
2A	0007283	biological_process	spermatogenesis
2A	0008380	biological_process	RNA splicing
2A	0016604	cellular_component	nuclear body
2A	0016607	cellular_component	nuclear speck
2A	0030532	cellular_component	small nuclear ribonucleoprotein complex
2A	0030620	molecular_function	U2 snRNA binding
2A	0071005	cellular_component	U2-type precatalytic spliceosome
2A	0071007	cellular_component	U2-type catalytic step 2 spliceosome
2A	0071013	cellular_component	catalytic step 2 spliceosome
2A	1903241	biological_process	U2-type prespliceosome assembly
2B	0000398	biological_process	mRNA splicing, via spliceosome
2B	0001650	cellular_component	fibrillar center
2B	0003676	molecular_function	nucleic acid binding
2B	0003723	molecular_function	RNA binding
2B	0005515	molecular_function	protein binding
2B	0005634	cellular_component	nucleus
2B	0005654	cellular_component	nucleoplasm
2B	0005681	cellular_component	spliceosomal complex
2B	0005684	cellular_component	U2-type spliceosomal complex
2B	0005685	cellular_component	U1 snRNP
2B	0005686	cellular_component	U2 snRNP
2B	0006397	biological_process	mRNA processing
2B	0008380	biological_process	RNA splicing
2B	0016607	cellular_component	nuclear speck
2B	0030532	cellular_component	small nuclear ribonucleoprotein complex
2B	0030619	molecular_function	U1 snRNA binding
2B	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
2B	0070990	molecular_function	snRNP binding
2B	0071005	cellular_component	U2-type precatalytic spliceosome
2B	0071007	cellular_component	U2-type catalytic step 2 spliceosome
2B	0071013	cellular_component	catalytic step 2 spliceosome
2B	1903241	biological_process	U2-type prespliceosome assembly
2b	0000387	biological_process	spliceosomal snRNP assembly
2b	0000398	biological_process	mRNA splicing, via spliceosome
2b	0003723	molecular_function	RNA binding
2b	0005515	molecular_function	protein binding
2b	0005634	cellular_component	nucleus
2b	0005654	cellular_component	nucleoplasm
2b	0005681	cellular_component	spliceosomal complex
2b	0005682	cellular_component	U5 snRNP
2b	0005683	cellular_component	U7 snRNP
2b	0005684	cellular_component	U2-type spliceosomal complex
2b	0005685	cellular_component	U1 snRNP
2b	0005686	cellular_component	U2 snRNP
2b	0005687	cellular_component	U4 snRNP
2b	0005689	cellular_component	U12-type spliceosomal complex
2b	0005697	cellular_component	telomerase holoenzyme complex
2b	0005737	cellular_component	cytoplasm
2b	0005829	cellular_component	cytosol
2b	0006397	biological_process	mRNA processing
2b	0006479	biological_process	protein methylation
2b	0008380	biological_process	RNA splicing
2b	0030532	cellular_component	small nuclear ribonucleoprotein complex
2b	0034709	cellular_component	methylosome
2b	0034719	cellular_component	SMN-Sm protein complex
2b	0036261	biological_process	7-methylguanosine cap hypermethylation
2b	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
2b	0070034	molecular_function	telomerase RNA binding
2b	0070990	molecular_function	snRNP binding
2b	0071004	cellular_component	U2-type prespliceosome
2b	0071005	cellular_component	U2-type precatalytic spliceosome
2b	0071007	cellular_component	U2-type catalytic step 2 spliceosome
2b	0071013	cellular_component	catalytic step 2 spliceosome
2b	0071204	cellular_component	histone pre-mRNA 3'end processing complex
2b	0071208	molecular_function	histone pre-mRNA DCP binding
2b	1903241	biological_process	U2-type prespliceosome assembly
2b	1990446	molecular_function	U1 snRNP binding
2b	1990447	molecular_function	U2 snRNP binding
2e	0000245	biological_process	spliceosomal complex assembly
2e	0000387	biological_process	spliceosomal snRNP assembly
2e	0000398	biological_process	mRNA splicing, via spliceosome
2e	0003723	molecular_function	RNA binding
2e	0005515	molecular_function	protein binding
2e	0005634	cellular_component	nucleus
2e	0005654	cellular_component	nucleoplasm
2e	0005681	cellular_component	spliceosomal complex
2e	0005682	cellular_component	U5 snRNP
2e	0005683	cellular_component	U7 snRNP
2e	0005684	cellular_component	U2-type spliceosomal complex
2e	0005685	cellular_component	U1 snRNP
2e	0005686	cellular_component	U2 snRNP
2e	0005687	cellular_component	U4 snRNP
2e	0005689	cellular_component	U12-type spliceosomal complex
2e	0005697	cellular_component	telomerase holoenzyme complex
2e	0005737	cellular_component	cytoplasm
2e	0005829	cellular_component	cytosol
2e	0006397	biological_process	mRNA processing
2e	0008380	biological_process	RNA splicing
2e	0030532	cellular_component	small nuclear ribonucleoprotein complex
2e	0034709	cellular_component	methylosome
2e	0034715	cellular_component	pICln-Sm protein complex
2e	0034719	cellular_component	SMN-Sm protein complex
2e	0036261	biological_process	7-methylguanosine cap hypermethylation
2e	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
2e	0071005	cellular_component	U2-type precatalytic spliceosome
2e	0071007	cellular_component	U2-type catalytic step 2 spliceosome
2e	0071011	cellular_component	precatalytic spliceosome
2e	0071013	cellular_component	catalytic step 2 spliceosome
2e	1903241	biological_process	U2-type prespliceosome assembly
2f	0000387	biological_process	spliceosomal snRNP assembly
2f	0000398	biological_process	mRNA splicing, via spliceosome
2f	0003723	molecular_function	RNA binding
2f	0005515	molecular_function	protein binding
2f	0005634	cellular_component	nucleus
2f	0005654	cellular_component	nucleoplasm
2f	0005681	cellular_component	spliceosomal complex
2f	0005682	cellular_component	U5 snRNP
2f	0005683	cellular_component	U7 snRNP
2f	0005684	cellular_component	U2-type spliceosomal complex
2f	0005685	cellular_component	U1 snRNP
2f	0005686	cellular_component	U2 snRNP
2f	0005687	cellular_component	U4 snRNP
2f	0005689	cellular_component	U12-type spliceosomal complex
2f	0005737	cellular_component	cytoplasm
2f	0005829	cellular_component	cytosol
2f	0006397	biological_process	mRNA processing
2f	0008380	biological_process	RNA splicing
2f	0030532	cellular_component	small nuclear ribonucleoprotein complex
2f	0034709	cellular_component	methylosome
2f	0034715	cellular_component	pICln-Sm protein complex
2f	0034719	cellular_component	SMN-Sm protein complex
2f	0036261	biological_process	7-methylguanosine cap hypermethylation
2f	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
2f	0071005	cellular_component	U2-type precatalytic spliceosome
2f	0071007	cellular_component	U2-type catalytic step 2 spliceosome
2f	0071013	cellular_component	catalytic step 2 spliceosome
2f	0120114	cellular_component	Sm-like protein family complex
2f	1903241	biological_process	U2-type prespliceosome assembly
2g	0000245	biological_process	spliceosomal complex assembly
2g	0000387	biological_process	spliceosomal snRNP assembly
2g	0000398	biological_process	mRNA splicing, via spliceosome
2g	0003723	molecular_function	RNA binding
2g	0005515	molecular_function	protein binding
2g	0005634	cellular_component	nucleus
2g	0005654	cellular_component	nucleoplasm
2g	0005681	cellular_component	spliceosomal complex
2g	0005682	cellular_component	U5 snRNP
2g	0005683	cellular_component	U7 snRNP
2g	0005684	cellular_component	U2-type spliceosomal complex
2g	0005685	cellular_component	U1 snRNP
2g	0005686	cellular_component	U2 snRNP
2g	0005687	cellular_component	U4 snRNP
2g	0005689	cellular_component	U12-type spliceosomal complex
2g	0005737	cellular_component	cytoplasm
2g	0005829	cellular_component	cytosol
2g	0006397	biological_process	mRNA processing
2g	0008380	biological_process	RNA splicing
2g	0030532	cellular_component	small nuclear ribonucleoprotein complex
2g	0034709	cellular_component	methylosome
2g	0034719	cellular_component	SMN-Sm protein complex
2g	0036261	biological_process	7-methylguanosine cap hypermethylation
2g	0043186	cellular_component	P granule
2g	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
2g	0071004	cellular_component	U2-type prespliceosome
2g	0071005	cellular_component	U2-type precatalytic spliceosome
2g	0071007	cellular_component	U2-type catalytic step 2 spliceosome
2g	0071011	cellular_component	precatalytic spliceosome
2g	0071013	cellular_component	catalytic step 2 spliceosome
2g	0097526	cellular_component	spliceosomal tri-snRNP complex
2g	1903241	biological_process	U2-type prespliceosome assembly
2g	1990446	molecular_function	U1 snRNP binding
41	0000243	cellular_component	commitment complex
41	0000245	biological_process	spliceosomal complex assembly
41	0000387	biological_process	spliceosomal snRNP assembly
41	0000398	biological_process	mRNA splicing, via spliceosome
41	0003723	molecular_function	RNA binding
41	0005515	molecular_function	protein binding
41	0005634	cellular_component	nucleus
41	0005654	cellular_component	nucleoplasm
41	0005681	cellular_component	spliceosomal complex
41	0005682	cellular_component	U5 snRNP
41	0005684	cellular_component	U2-type spliceosomal complex
41	0005685	cellular_component	U1 snRNP
41	0005686	cellular_component	U2 snRNP
41	0005687	cellular_component	U4 snRNP
41	0005689	cellular_component	U12-type spliceosomal complex
41	0005737	cellular_component	cytoplasm
41	0005829	cellular_component	cytosol
41	0006396	biological_process	RNA processing
41	0006397	biological_process	mRNA processing
41	0008380	biological_process	RNA splicing
41	0030532	cellular_component	small nuclear ribonucleoprotein complex
41	0034709	cellular_component	methylosome
41	0034715	cellular_component	pICln-Sm protein complex
41	0034719	cellular_component	SMN-Sm protein complex
41	0036261	biological_process	7-methylguanosine cap hypermethylation
41	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
41	0071005	cellular_component	U2-type precatalytic spliceosome
41	0071007	cellular_component	U2-type catalytic step 2 spliceosome
41	0071011	cellular_component	precatalytic spliceosome
41	0071013	cellular_component	catalytic step 2 spliceosome
41	0097526	cellular_component	spliceosomal tri-snRNP complex
41	1903241	biological_process	U2-type prespliceosome assembly
41	1990446	molecular_function	U1 snRNP binding
42	0000245	biological_process	spliceosomal complex assembly
42	0000387	biological_process	spliceosomal snRNP assembly
42	0000398	biological_process	mRNA splicing, via spliceosome
42	0003723	molecular_function	RNA binding
42	0005515	molecular_function	protein binding
42	0005634	cellular_component	nucleus
42	0005654	cellular_component	nucleoplasm
42	0005681	cellular_component	spliceosomal complex
42	0005682	cellular_component	U5 snRNP
42	0005684	cellular_component	U2-type spliceosomal complex
42	0005685	cellular_component	U1 snRNP
42	0005686	cellular_component	U2 snRNP
42	0005687	cellular_component	U4 snRNP
42	0005689	cellular_component	U12-type spliceosomal complex
42	0005737	cellular_component	cytoplasm
42	0005829	cellular_component	cytosol
42	0006397	biological_process	mRNA processing
42	0008380	biological_process	RNA splicing
42	0030532	cellular_component	small nuclear ribonucleoprotein complex
42	0034709	cellular_component	methylosome
42	0034715	cellular_component	pICln-Sm protein complex
42	0034719	cellular_component	SMN-Sm protein complex
42	0036261	biological_process	7-methylguanosine cap hypermethylation
42	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
42	0070062	cellular_component	extracellular exosome
42	0071005	cellular_component	U2-type precatalytic spliceosome
42	0071007	cellular_component	U2-type catalytic step 2 spliceosome
42	0071011	cellular_component	precatalytic spliceosome
42	0071013	cellular_component	catalytic step 2 spliceosome
42	1903241	biological_process	U2-type prespliceosome assembly
43	0000243	cellular_component	commitment complex
43	0000387	biological_process	spliceosomal snRNP assembly
43	0000398	biological_process	mRNA splicing, via spliceosome
43	0003723	molecular_function	RNA binding
43	0005515	molecular_function	protein binding
43	0005634	cellular_component	nucleus
43	0005654	cellular_component	nucleoplasm
43	0005681	cellular_component	spliceosomal complex
43	0005682	cellular_component	U5 snRNP
43	0005683	cellular_component	U7 snRNP
43	0005684	cellular_component	U2-type spliceosomal complex
43	0005685	cellular_component	U1 snRNP
43	0005686	cellular_component	U2 snRNP
43	0005687	cellular_component	U4 snRNP
43	0005689	cellular_component	U12-type spliceosomal complex
43	0005697	cellular_component	telomerase holoenzyme complex
43	0005737	cellular_component	cytoplasm
43	0005829	cellular_component	cytosol
43	0006396	biological_process	RNA processing
43	0006397	biological_process	mRNA processing
43	0006479	biological_process	protein methylation
43	0008380	biological_process	RNA splicing
43	0016604	cellular_component	nuclear body
43	0019899	molecular_function	enzyme binding
43	0030532	cellular_component	small nuclear ribonucleoprotein complex
43	0034709	cellular_component	methylosome
43	0034715	cellular_component	pICln-Sm protein complex
43	0034719	cellular_component	SMN-Sm protein complex
43	0036261	biological_process	7-methylguanosine cap hypermethylation
43	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
43	0070034	molecular_function	telomerase RNA binding
43	0071005	cellular_component	U2-type precatalytic spliceosome
43	0071007	cellular_component	U2-type catalytic step 2 spliceosome
43	0071011	cellular_component	precatalytic spliceosome
43	0071013	cellular_component	catalytic step 2 spliceosome
43	0071208	molecular_function	histone pre-mRNA DCP binding
43	0071209	molecular_function	U7 snRNA binding
43	0097526	cellular_component	spliceosomal tri-snRNP complex
43	1903241	biological_process	U2-type prespliceosome assembly
4b	0000387	biological_process	spliceosomal snRNP assembly
4b	0000398	biological_process	mRNA splicing, via spliceosome
4b	0003723	molecular_function	RNA binding
4b	0005515	molecular_function	protein binding
4b	0005634	cellular_component	nucleus
4b	0005654	cellular_component	nucleoplasm
4b	0005681	cellular_component	spliceosomal complex
4b	0005682	cellular_component	U5 snRNP
4b	0005683	cellular_component	U7 snRNP
4b	0005684	cellular_component	U2-type spliceosomal complex
4b	0005685	cellular_component	U1 snRNP
4b	0005686	cellular_component	U2 snRNP
4b	0005687	cellular_component	U4 snRNP
4b	0005689	cellular_component	U12-type spliceosomal complex
4b	0005697	cellular_component	telomerase holoenzyme complex
4b	0005737	cellular_component	cytoplasm
4b	0005829	cellular_component	cytosol
4b	0006397	biological_process	mRNA processing
4b	0006479	biological_process	protein methylation
4b	0008380	biological_process	RNA splicing
4b	0030532	cellular_component	small nuclear ribonucleoprotein complex
4b	0034709	cellular_component	methylosome
4b	0034719	cellular_component	SMN-Sm protein complex
4b	0036261	biological_process	7-methylguanosine cap hypermethylation
4b	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
4b	0070034	molecular_function	telomerase RNA binding
4b	0070990	molecular_function	snRNP binding
4b	0071004	cellular_component	U2-type prespliceosome
4b	0071005	cellular_component	U2-type precatalytic spliceosome
4b	0071007	cellular_component	U2-type catalytic step 2 spliceosome
4b	0071013	cellular_component	catalytic step 2 spliceosome
4b	0071204	cellular_component	histone pre-mRNA 3'end processing complex
4b	0071208	molecular_function	histone pre-mRNA DCP binding
4b	1903241	biological_process	U2-type prespliceosome assembly
4b	1990446	molecular_function	U1 snRNP binding
4b	1990447	molecular_function	U2 snRNP binding
4e	0000245	biological_process	spliceosomal complex assembly
4e	0000387	biological_process	spliceosomal snRNP assembly
4e	0000398	biological_process	mRNA splicing, via spliceosome
4e	0003723	molecular_function	RNA binding
4e	0005515	molecular_function	protein binding
4e	0005634	cellular_component	nucleus
4e	0005654	cellular_component	nucleoplasm
4e	0005681	cellular_component	spliceosomal complex
4e	0005682	cellular_component	U5 snRNP
4e	0005683	cellular_component	U7 snRNP
4e	0005684	cellular_component	U2-type spliceosomal complex
4e	0005685	cellular_component	U1 snRNP
4e	0005686	cellular_component	U2 snRNP
4e	0005687	cellular_component	U4 snRNP
4e	0005689	cellular_component	U12-type spliceosomal complex
4e	0005697	cellular_component	telomerase holoenzyme complex
4e	0005737	cellular_component	cytoplasm
4e	0005829	cellular_component	cytosol
4e	0006397	biological_process	mRNA processing
4e	0008380	biological_process	RNA splicing
4e	0030532	cellular_component	small nuclear ribonucleoprotein complex
4e	0034709	cellular_component	methylosome
4e	0034715	cellular_component	pICln-Sm protein complex
4e	0034719	cellular_component	SMN-Sm protein complex
4e	0036261	biological_process	7-methylguanosine cap hypermethylation
4e	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
4e	0071005	cellular_component	U2-type precatalytic spliceosome
4e	0071007	cellular_component	U2-type catalytic step 2 spliceosome
4e	0071011	cellular_component	precatalytic spliceosome
4e	0071013	cellular_component	catalytic step 2 spliceosome
4e	1903241	biological_process	U2-type prespliceosome assembly
4f	0000387	biological_process	spliceosomal snRNP assembly
4f	0000398	biological_process	mRNA splicing, via spliceosome
4f	0003723	molecular_function	RNA binding
4f	0005515	molecular_function	protein binding
4f	0005634	cellular_component	nucleus
4f	0005654	cellular_component	nucleoplasm
4f	0005681	cellular_component	spliceosomal complex
4f	0005682	cellular_component	U5 snRNP
4f	0005683	cellular_component	U7 snRNP
4f	0005684	cellular_component	U2-type spliceosomal complex
4f	0005685	cellular_component	U1 snRNP
4f	0005686	cellular_component	U2 snRNP
4f	0005687	cellular_component	U4 snRNP
4f	0005689	cellular_component	U12-type spliceosomal complex
4f	0005737	cellular_component	cytoplasm
4f	0005829	cellular_component	cytosol
4f	0006397	biological_process	mRNA processing
4f	0008380	biological_process	RNA splicing
4f	0030532	cellular_component	small nuclear ribonucleoprotein complex
4f	0034709	cellular_component	methylosome
4f	0034715	cellular_component	pICln-Sm protein complex
4f	0034719	cellular_component	SMN-Sm protein complex
4f	0036261	biological_process	7-methylguanosine cap hypermethylation
4f	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
4f	0071005	cellular_component	U2-type precatalytic spliceosome
4f	0071007	cellular_component	U2-type catalytic step 2 spliceosome
4f	0071013	cellular_component	catalytic step 2 spliceosome
4f	0120114	cellular_component	Sm-like protein family complex
4f	1903241	biological_process	U2-type prespliceosome assembly
4g	0000245	biological_process	spliceosomal complex assembly
4g	0000387	biological_process	spliceosomal snRNP assembly
4g	0000398	biological_process	mRNA splicing, via spliceosome
4g	0003723	molecular_function	RNA binding
4g	0005515	molecular_function	protein binding
4g	0005634	cellular_component	nucleus
4g	0005654	cellular_component	nucleoplasm
4g	0005681	cellular_component	spliceosomal complex
4g	0005682	cellular_component	U5 snRNP
4g	0005683	cellular_component	U7 snRNP
4g	0005684	cellular_component	U2-type spliceosomal complex
4g	0005685	cellular_component	U1 snRNP
4g	0005686	cellular_component	U2 snRNP
4g	0005687	cellular_component	U4 snRNP
4g	0005689	cellular_component	U12-type spliceosomal complex
4g	0005737	cellular_component	cytoplasm
4g	0005829	cellular_component	cytosol
4g	0006397	biological_process	mRNA processing
4g	0008380	biological_process	RNA splicing
4g	0030532	cellular_component	small nuclear ribonucleoprotein complex
4g	0034709	cellular_component	methylosome
4g	0034719	cellular_component	SMN-Sm protein complex
4g	0036261	biological_process	7-methylguanosine cap hypermethylation
4g	0043186	cellular_component	P granule
4g	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
4g	0071004	cellular_component	U2-type prespliceosome
4g	0071005	cellular_component	U2-type precatalytic spliceosome
4g	0071007	cellular_component	U2-type catalytic step 2 spliceosome
4g	0071011	cellular_component	precatalytic spliceosome
4g	0071013	cellular_component	catalytic step 2 spliceosome
4g	0097526	cellular_component	spliceosomal tri-snRNP complex
4g	1903241	biological_process	U2-type prespliceosome assembly
4g	1990446	molecular_function	U1 snRNP binding
51	0000243	cellular_component	commitment complex
51	0000245	biological_process	spliceosomal complex assembly
51	0000387	biological_process	spliceosomal snRNP assembly
51	0000398	biological_process	mRNA splicing, via spliceosome
51	0003723	molecular_function	RNA binding
51	0005515	molecular_function	protein binding
51	0005634	cellular_component	nucleus
51	0005654	cellular_component	nucleoplasm
51	0005681	cellular_component	spliceosomal complex
51	0005682	cellular_component	U5 snRNP
51	0005684	cellular_component	U2-type spliceosomal complex
51	0005685	cellular_component	U1 snRNP
51	0005686	cellular_component	U2 snRNP
51	0005687	cellular_component	U4 snRNP
51	0005689	cellular_component	U12-type spliceosomal complex
51	0005737	cellular_component	cytoplasm
51	0005829	cellular_component	cytosol
51	0006396	biological_process	RNA processing
51	0006397	biological_process	mRNA processing
51	0008380	biological_process	RNA splicing
51	0030532	cellular_component	small nuclear ribonucleoprotein complex
51	0034709	cellular_component	methylosome
51	0034715	cellular_component	pICln-Sm protein complex
51	0034719	cellular_component	SMN-Sm protein complex
51	0036261	biological_process	7-methylguanosine cap hypermethylation
51	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
51	0071005	cellular_component	U2-type precatalytic spliceosome
51	0071007	cellular_component	U2-type catalytic step 2 spliceosome
51	0071011	cellular_component	precatalytic spliceosome
51	0071013	cellular_component	catalytic step 2 spliceosome
51	0097526	cellular_component	spliceosomal tri-snRNP complex
51	1903241	biological_process	U2-type prespliceosome assembly
51	1990446	molecular_function	U1 snRNP binding
52	0000245	biological_process	spliceosomal complex assembly
52	0000387	biological_process	spliceosomal snRNP assembly
52	0000398	biological_process	mRNA splicing, via spliceosome
52	0003723	molecular_function	RNA binding
52	0005515	molecular_function	protein binding
52	0005634	cellular_component	nucleus
52	0005654	cellular_component	nucleoplasm
52	0005681	cellular_component	spliceosomal complex
52	0005682	cellular_component	U5 snRNP
52	0005684	cellular_component	U2-type spliceosomal complex
52	0005685	cellular_component	U1 snRNP
52	0005686	cellular_component	U2 snRNP
52	0005687	cellular_component	U4 snRNP
52	0005689	cellular_component	U12-type spliceosomal complex
52	0005737	cellular_component	cytoplasm
52	0005829	cellular_component	cytosol
52	0006397	biological_process	mRNA processing
52	0008380	biological_process	RNA splicing
52	0030532	cellular_component	small nuclear ribonucleoprotein complex
52	0034709	cellular_component	methylosome
52	0034715	cellular_component	pICln-Sm protein complex
52	0034719	cellular_component	SMN-Sm protein complex
52	0036261	biological_process	7-methylguanosine cap hypermethylation
52	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
52	0070062	cellular_component	extracellular exosome
52	0071005	cellular_component	U2-type precatalytic spliceosome
52	0071007	cellular_component	U2-type catalytic step 2 spliceosome
52	0071011	cellular_component	precatalytic spliceosome
52	0071013	cellular_component	catalytic step 2 spliceosome
52	1903241	biological_process	U2-type prespliceosome assembly
53	0000243	cellular_component	commitment complex
53	0000387	biological_process	spliceosomal snRNP assembly
53	0000398	biological_process	mRNA splicing, via spliceosome
53	0003723	molecular_function	RNA binding
53	0005515	molecular_function	protein binding
53	0005634	cellular_component	nucleus
53	0005654	cellular_component	nucleoplasm
53	0005681	cellular_component	spliceosomal complex
53	0005682	cellular_component	U5 snRNP
53	0005683	cellular_component	U7 snRNP
53	0005684	cellular_component	U2-type spliceosomal complex
53	0005685	cellular_component	U1 snRNP
53	0005686	cellular_component	U2 snRNP
53	0005687	cellular_component	U4 snRNP
53	0005689	cellular_component	U12-type spliceosomal complex
53	0005697	cellular_component	telomerase holoenzyme complex
53	0005737	cellular_component	cytoplasm
53	0005829	cellular_component	cytosol
53	0006396	biological_process	RNA processing
53	0006397	biological_process	mRNA processing
53	0006479	biological_process	protein methylation
53	0008380	biological_process	RNA splicing
53	0016604	cellular_component	nuclear body
53	0019899	molecular_function	enzyme binding
53	0030532	cellular_component	small nuclear ribonucleoprotein complex
53	0034709	cellular_component	methylosome
53	0034715	cellular_component	pICln-Sm protein complex
53	0034719	cellular_component	SMN-Sm protein complex
53	0036261	biological_process	7-methylguanosine cap hypermethylation
53	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
53	0070034	molecular_function	telomerase RNA binding
53	0071005	cellular_component	U2-type precatalytic spliceosome
53	0071007	cellular_component	U2-type catalytic step 2 spliceosome
53	0071011	cellular_component	precatalytic spliceosome
53	0071013	cellular_component	catalytic step 2 spliceosome
53	0071208	molecular_function	histone pre-mRNA DCP binding
53	0071209	molecular_function	U7 snRNA binding
53	0097526	cellular_component	spliceosomal tri-snRNP complex
53	1903241	biological_process	U2-type prespliceosome assembly
5b	0000387	biological_process	spliceosomal snRNP assembly
5b	0000398	biological_process	mRNA splicing, via spliceosome
5b	0003723	molecular_function	RNA binding
5b	0005515	molecular_function	protein binding
5b	0005634	cellular_component	nucleus
5b	0005654	cellular_component	nucleoplasm
5b	0005681	cellular_component	spliceosomal complex
5b	0005682	cellular_component	U5 snRNP
5b	0005683	cellular_component	U7 snRNP
5b	0005684	cellular_component	U2-type spliceosomal complex
5b	0005685	cellular_component	U1 snRNP
5b	0005686	cellular_component	U2 snRNP
5b	0005687	cellular_component	U4 snRNP
5b	0005689	cellular_component	U12-type spliceosomal complex
5b	0005697	cellular_component	telomerase holoenzyme complex
5b	0005737	cellular_component	cytoplasm
5b	0005829	cellular_component	cytosol
5b	0006397	biological_process	mRNA processing
5b	0006479	biological_process	protein methylation
5b	0008380	biological_process	RNA splicing
5b	0030532	cellular_component	small nuclear ribonucleoprotein complex
5b	0034709	cellular_component	methylosome
5b	0034719	cellular_component	SMN-Sm protein complex
5b	0036261	biological_process	7-methylguanosine cap hypermethylation
5b	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
5b	0070034	molecular_function	telomerase RNA binding
5b	0070990	molecular_function	snRNP binding
5b	0071004	cellular_component	U2-type prespliceosome
5b	0071005	cellular_component	U2-type precatalytic spliceosome
5b	0071007	cellular_component	U2-type catalytic step 2 spliceosome
5b	0071013	cellular_component	catalytic step 2 spliceosome
5b	0071204	cellular_component	histone pre-mRNA 3'end processing complex
5b	0071208	molecular_function	histone pre-mRNA DCP binding
5b	1903241	biological_process	U2-type prespliceosome assembly
5b	1990446	molecular_function	U1 snRNP binding
5b	1990447	molecular_function	U2 snRNP binding
5e	0000245	biological_process	spliceosomal complex assembly
5e	0000387	biological_process	spliceosomal snRNP assembly
5e	0000398	biological_process	mRNA splicing, via spliceosome
5e	0003723	molecular_function	RNA binding
5e	0005515	molecular_function	protein binding
5e	0005634	cellular_component	nucleus
5e	0005654	cellular_component	nucleoplasm
5e	0005681	cellular_component	spliceosomal complex
5e	0005682	cellular_component	U5 snRNP
5e	0005683	cellular_component	U7 snRNP
5e	0005684	cellular_component	U2-type spliceosomal complex
5e	0005685	cellular_component	U1 snRNP
5e	0005686	cellular_component	U2 snRNP
5e	0005687	cellular_component	U4 snRNP
5e	0005689	cellular_component	U12-type spliceosomal complex
5e	0005697	cellular_component	telomerase holoenzyme complex
5e	0005737	cellular_component	cytoplasm
5e	0005829	cellular_component	cytosol
5e	0006397	biological_process	mRNA processing
5e	0008380	biological_process	RNA splicing
5e	0030532	cellular_component	small nuclear ribonucleoprotein complex
5e	0034709	cellular_component	methylosome
5e	0034715	cellular_component	pICln-Sm protein complex
5e	0034719	cellular_component	SMN-Sm protein complex
5e	0036261	biological_process	7-methylguanosine cap hypermethylation
5e	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
5e	0071005	cellular_component	U2-type precatalytic spliceosome
5e	0071007	cellular_component	U2-type catalytic step 2 spliceosome
5e	0071011	cellular_component	precatalytic spliceosome
5e	0071013	cellular_component	catalytic step 2 spliceosome
5e	1903241	biological_process	U2-type prespliceosome assembly
5f	0000387	biological_process	spliceosomal snRNP assembly
5f	0000398	biological_process	mRNA splicing, via spliceosome
5f	0003723	molecular_function	RNA binding
5f	0005515	molecular_function	protein binding
5f	0005634	cellular_component	nucleus
5f	0005654	cellular_component	nucleoplasm
5f	0005681	cellular_component	spliceosomal complex
5f	0005682	cellular_component	U5 snRNP
5f	0005683	cellular_component	U7 snRNP
5f	0005684	cellular_component	U2-type spliceosomal complex
5f	0005685	cellular_component	U1 snRNP
5f	0005686	cellular_component	U2 snRNP
5f	0005687	cellular_component	U4 snRNP
5f	0005689	cellular_component	U12-type spliceosomal complex
5f	0005737	cellular_component	cytoplasm
5f	0005829	cellular_component	cytosol
5f	0006397	biological_process	mRNA processing
5f	0008380	biological_process	RNA splicing
5f	0030532	cellular_component	small nuclear ribonucleoprotein complex
5f	0034709	cellular_component	methylosome
5f	0034715	cellular_component	pICln-Sm protein complex
5f	0034719	cellular_component	SMN-Sm protein complex
5f	0036261	biological_process	7-methylguanosine cap hypermethylation
5f	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
5f	0071005	cellular_component	U2-type precatalytic spliceosome
5f	0071007	cellular_component	U2-type catalytic step 2 spliceosome
5f	0071013	cellular_component	catalytic step 2 spliceosome
5f	0120114	cellular_component	Sm-like protein family complex
5f	1903241	biological_process	U2-type prespliceosome assembly
5g	0000245	biological_process	spliceosomal complex assembly
5g	0000387	biological_process	spliceosomal snRNP assembly
5g	0000398	biological_process	mRNA splicing, via spliceosome
5g	0003723	molecular_function	RNA binding
5g	0005515	molecular_function	protein binding
5g	0005634	cellular_component	nucleus
5g	0005654	cellular_component	nucleoplasm
5g	0005681	cellular_component	spliceosomal complex
5g	0005682	cellular_component	U5 snRNP
5g	0005683	cellular_component	U7 snRNP
5g	0005684	cellular_component	U2-type spliceosomal complex
5g	0005685	cellular_component	U1 snRNP
5g	0005686	cellular_component	U2 snRNP
5g	0005687	cellular_component	U4 snRNP
5g	0005689	cellular_component	U12-type spliceosomal complex
5g	0005737	cellular_component	cytoplasm
5g	0005829	cellular_component	cytosol
5g	0006397	biological_process	mRNA processing
5g	0008380	biological_process	RNA splicing
5g	0030532	cellular_component	small nuclear ribonucleoprotein complex
5g	0034709	cellular_component	methylosome
5g	0034719	cellular_component	SMN-Sm protein complex
5g	0036261	biological_process	7-methylguanosine cap hypermethylation
5g	0043186	cellular_component	P granule
5g	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
5g	0071004	cellular_component	U2-type prespliceosome
5g	0071005	cellular_component	U2-type precatalytic spliceosome
5g	0071007	cellular_component	U2-type catalytic step 2 spliceosome
5g	0071011	cellular_component	precatalytic spliceosome
5g	0071013	cellular_component	catalytic step 2 spliceosome
5g	0097526	cellular_component	spliceosomal tri-snRNP complex
5g	1903241	biological_process	U2-type prespliceosome assembly
5g	1990446	molecular_function	U1 snRNP binding
62	0000244	biological_process	spliceosomal tri-snRNP complex assembly
62	0000398	biological_process	mRNA splicing, via spliceosome
62	0000932	cellular_component	P-body
62	0003723	molecular_function	RNA binding
62	0005515	molecular_function	protein binding
62	0005634	cellular_component	nucleus
62	0005654	cellular_component	nucleoplasm
62	0005681	cellular_component	spliceosomal complex
62	0005688	cellular_component	U6 snRNP
62	0005737	cellular_component	cytoplasm
62	0005829	cellular_component	cytosol
62	0006397	biological_process	mRNA processing
62	0006402	biological_process	mRNA catabolic process
62	0008380	biological_process	RNA splicing
62	0017070	molecular_function	U6 snRNA binding
62	0031267	molecular_function	small GTPase binding
62	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
62	0071005	cellular_component	U2-type precatalytic spliceosome
62	0071011	cellular_component	precatalytic spliceosome
62	0071013	cellular_component	catalytic step 2 spliceosome
62	0120115	cellular_component	Lsm2-8 complex
62	1990726	cellular_component	Lsm1-7-Pat1 complex
63	0000398	biological_process	mRNA splicing, via spliceosome
63	0000932	cellular_component	P-body
63	0003723	molecular_function	RNA binding
63	0005515	molecular_function	protein binding
63	0005634	cellular_component	nucleus
63	0005654	cellular_component	nucleoplasm
63	0005681	cellular_component	spliceosomal complex
63	0005688	cellular_component	U6 snRNP
63	0005829	cellular_component	cytosol
63	0006397	biological_process	mRNA processing
63	0008380	biological_process	RNA splicing
63	0030629	molecular_function	U6 snRNA 3'-end binding
63	0033962	biological_process	P-body assembly
63	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
63	0071005	cellular_component	U2-type precatalytic spliceosome
63	0071011	cellular_component	precatalytic spliceosome
63	0071013	cellular_component	catalytic step 2 spliceosome
63	0120114	cellular_component	Sm-like protein family complex
63	0120115	cellular_component	Lsm2-8 complex
63	1990726	cellular_component	Lsm1-7-Pat1 complex
64	0000387	biological_process	spliceosomal snRNP assembly
64	0000398	biological_process	mRNA splicing, via spliceosome
64	0000932	cellular_component	P-body
64	0000956	biological_process	nuclear-transcribed mRNA catabolic process
64	0003723	molecular_function	RNA binding
64	0005515	molecular_function	protein binding
64	0005634	cellular_component	nucleus
64	0005654	cellular_component	nucleoplasm
64	0005681	cellular_component	spliceosomal complex
64	0005688	cellular_component	U6 snRNP
64	0005829	cellular_component	cytosol
64	0006396	biological_process	RNA processing
64	0006397	biological_process	mRNA processing
64	0008380	biological_process	RNA splicing
64	0016020	cellular_component	membrane
64	0017070	molecular_function	U6 snRNA binding
64	0032991	cellular_component	protein-containing complex
64	0033962	biological_process	P-body assembly
64	0042731	molecular_function	PH domain binding
64	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
64	0071005	cellular_component	U2-type precatalytic spliceosome
64	0097526	cellular_component	spliceosomal tri-snRNP complex
64	0120115	cellular_component	Lsm2-8 complex
65	0000398	biological_process	mRNA splicing, via spliceosome
65	0003723	molecular_function	RNA binding
65	0005515	molecular_function	protein binding
65	0005634	cellular_component	nucleus
65	0005654	cellular_component	nucleoplasm
65	0005681	cellular_component	spliceosomal complex
65	0005688	cellular_component	U6 snRNP
65	0005737	cellular_component	cytoplasm
65	0005829	cellular_component	cytosol
65	0006397	biological_process	mRNA processing
65	0006402	biological_process	mRNA catabolic process
65	0008380	biological_process	RNA splicing
65	0009617	biological_process	response to bacterium
65	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
65	0046982	molecular_function	protein heterodimerization activity
65	0071005	cellular_component	U2-type precatalytic spliceosome
65	0120115	cellular_component	Lsm2-8 complex
65	1990726	cellular_component	Lsm1-7-Pat1 complex
66	0000398	biological_process	mRNA splicing, via spliceosome
66	0000932	cellular_component	P-body
66	0003723	molecular_function	RNA binding
66	0005515	molecular_function	protein binding
66	0005634	cellular_component	nucleus
66	0005654	cellular_component	nucleoplasm
66	0005681	cellular_component	spliceosomal complex
66	0005688	cellular_component	U6 snRNP
66	0005730	cellular_component	nucleolus
66	0005732	cellular_component	sno(s)RNA-containing ribonucleoprotein complex
66	0005737	cellular_component	cytoplasm
66	0005829	cellular_component	cytosol
66	0006364	biological_process	rRNA processing
66	0006397	biological_process	mRNA processing
66	0006402	biological_process	mRNA catabolic process
66	0008033	biological_process	tRNA processing
66	0008380	biological_process	RNA splicing
66	0030490	biological_process	maturation of SSU-rRNA
66	0030532	cellular_component	small nuclear ribonucleoprotein complex
66	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
66	0046982	molecular_function	protein heterodimerization activity
66	0071005	cellular_component	U2-type precatalytic spliceosome
66	0120114	cellular_component	Sm-like protein family complex
66	0120115	cellular_component	Lsm2-8 complex
67	0000398	biological_process	mRNA splicing, via spliceosome
67	0000956	biological_process	nuclear-transcribed mRNA catabolic process
67	0003723	molecular_function	RNA binding
67	0005515	molecular_function	protein binding
67	0005634	cellular_component	nucleus
67	0005654	cellular_component	nucleoplasm
67	0005681	cellular_component	spliceosomal complex
67	0005688	cellular_component	U6 snRNP
67	0005689	cellular_component	U12-type spliceosomal complex
67	0005829	cellular_component	cytosol
67	0006397	biological_process	mRNA processing
67	0008380	biological_process	RNA splicing
67	0017070	molecular_function	U6 snRNA binding
67	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
67	0071004	cellular_component	U2-type prespliceosome
67	0071005	cellular_component	U2-type precatalytic spliceosome
67	0071013	cellular_component	catalytic step 2 spliceosome
67	0097526	cellular_component	spliceosomal tri-snRNP complex
67	0120115	cellular_component	Lsm2-8 complex
67	1990726	cellular_component	Lsm1-7-Pat1 complex
68	0000398	biological_process	mRNA splicing, via spliceosome
68	0003723	molecular_function	RNA binding
68	0003729	molecular_function	mRNA binding
68	0005515	molecular_function	protein binding
68	0005634	cellular_component	nucleus
68	0005654	cellular_component	nucleoplasm
68	0005681	cellular_component	spliceosomal complex
68	0005688	cellular_component	U6 snRNP
68	0006397	biological_process	mRNA processing
68	0008380	biological_process	RNA splicing
68	0017070	molecular_function	U6 snRNA binding
68	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
68	0071005	cellular_component	U2-type precatalytic spliceosome
68	0071011	cellular_component	precatalytic spliceosome
68	0120115	cellular_component	Lsm2-8 complex
7	0000389	biological_process	mRNA 3'-splice site recognition
7	0000398	biological_process	mRNA splicing, via spliceosome
7	0003723	molecular_function	RNA binding
7	0005515	molecular_function	protein binding
7	0005634	cellular_component	nucleus
7	0005654	cellular_component	nucleoplasm
7	0005681	cellular_component	spliceosomal complex
7	0005684	cellular_component	U2-type spliceosomal complex
7	0005686	cellular_component	U2 snRNP
7	0006396	biological_process	RNA processing
7	0006397	biological_process	mRNA processing
7	0008380	biological_process	RNA splicing
7	0016607	cellular_component	nuclear speck
7	0045292	biological_process	mRNA cis splicing, via spliceosome
7	0071004	cellular_component	U2-type prespliceosome
7	0071005	cellular_component	U2-type precatalytic spliceosome
7	0071013	cellular_component	catalytic step 2 spliceosome
7	1903241	biological_process	U2-type prespliceosome assembly
8	0000245	biological_process	spliceosomal complex assembly
8	0000389	biological_process	mRNA 3'-splice site recognition
8	0000398	biological_process	mRNA splicing, via spliceosome
8	0003676	molecular_function	nucleic acid binding
8	0003723	molecular_function	RNA binding
8	0005515	molecular_function	protein binding
8	0005634	cellular_component	nucleus
8	0005654	cellular_component	nucleoplasm
8	0005681	cellular_component	spliceosomal complex
8	0005684	cellular_component	U2-type spliceosomal complex
8	0005686	cellular_component	U2 snRNP
8	0006397	biological_process	mRNA processing
8	0008270	molecular_function	zinc ion binding
8	0008380	biological_process	RNA splicing
8	0010976	biological_process	positive regulation of neuron projection development
8	0016607	cellular_component	nuclear speck
8	0046872	molecular_function	metal ion binding
8	0071004	cellular_component	U2-type prespliceosome
8	0071005	cellular_component	U2-type precatalytic spliceosome
8	0071013	cellular_component	catalytic step 2 spliceosome
8	1903241	biological_process	U2-type prespliceosome assembly
9	0000375	biological_process	RNA splicing, via transesterification reactions
9	0000389	biological_process	mRNA 3'-splice site recognition
9	0000398	biological_process	mRNA splicing, via spliceosome
9	0003676	molecular_function	nucleic acid binding
9	0003723	molecular_function	RNA binding
9	0005515	molecular_function	protein binding
9	0005634	cellular_component	nucleus
9	0005654	cellular_component	nucleoplasm
9	0005681	cellular_component	spliceosomal complex
9	0005684	cellular_component	U2-type spliceosomal complex
9	0005686	cellular_component	U2 snRNP
9	0006397	biological_process	mRNA processing
9	0008270	molecular_function	zinc ion binding
9	0008380	biological_process	RNA splicing
9	0016607	cellular_component	nuclear speck
9	0046872	molecular_function	metal ion binding
9	0071005	cellular_component	U2-type precatalytic spliceosome
9	0071013	cellular_component	catalytic step 2 spliceosome
9	1903241	biological_process	U2-type prespliceosome assembly
A	0000244	biological_process	spliceosomal tri-snRNP complex assembly
A	0000375	biological_process	RNA splicing, via transesterification reactions
A	0000398	biological_process	mRNA splicing, via spliceosome
A	0003723	molecular_function	RNA binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005681	cellular_component	spliceosomal complex
A	0005682	cellular_component	U5 snRNP
A	0006397	biological_process	mRNA processing
A	0008233	molecular_function	peptidase activity
A	0008237	molecular_function	metallopeptidase activity
A	0008380	biological_process	RNA splicing
A	0016020	cellular_component	membrane
A	0016607	cellular_component	nuclear speck
A	0017070	molecular_function	U6 snRNA binding
A	0030532	cellular_component	small nuclear ribonucleoprotein complex
A	0030619	molecular_function	U1 snRNA binding
A	0030620	molecular_function	U2 snRNA binding
A	0030623	molecular_function	U5 snRNA binding
A	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
A	0070530	molecular_function	K63-linked polyubiquitin modification-dependent protein binding
A	0071005	cellular_component	U2-type precatalytic spliceosome
A	0071006	cellular_component	U2-type catalytic step 1 spliceosome
A	0071007	cellular_component	U2-type catalytic step 2 spliceosome
A	0071013	cellular_component	catalytic step 2 spliceosome
A	0071222	biological_process	cellular response to lipopolysaccharide
A	0071356	biological_process	cellular response to tumor necrosis factor
A	0097157	molecular_function	pre-mRNA intronic binding
A	0140492	molecular_function	metal-dependent deubiquitinase activity
B	0000354	biological_process	cis assembly of pre-catalytic spliceosome
B	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
B	0000398	biological_process	mRNA splicing, via spliceosome
B	0001649	biological_process	osteoblast differentiation
B	0003676	molecular_function	nucleic acid binding
B	0003689	molecular_function	DNA clamp loader activity
B	0003723	molecular_function	RNA binding
B	0003724	molecular_function	RNA helicase activity
B	0004386	molecular_function	helicase activity
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005681	cellular_component	spliceosomal complex
B	0005682	cellular_component	U5 snRNP
B	0006338	biological_process	chromatin remodeling
B	0006397	biological_process	mRNA processing
B	0008380	biological_process	RNA splicing
B	0016020	cellular_component	membrane
B	0016787	molecular_function	hydrolase activity
B	0016887	molecular_function	ATP hydrolysis activity
B	0042802	molecular_function	identical protein binding
B	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
B	0061775	molecular_function	cohesin loader activity
B	0071005	cellular_component	U2-type precatalytic spliceosome
B	0071006	cellular_component	U2-type catalytic step 1 spliceosome
B	0071013	cellular_component	catalytic step 2 spliceosome
B	0140584	molecular_function	chromatin extrusion motor activity
B	0140588	biological_process	chromatin looping
B	0140665	molecular_function	ATP-dependent H3-H4 histone complex chaperone activity
B	0140849	molecular_function	ATP-dependent H2AZ histone chaperone activity
B1	0000245	biological_process	spliceosomal complex assembly
B1	0000375	biological_process	RNA splicing, via transesterification reactions
B1	0000398	biological_process	mRNA splicing, via spliceosome
B1	0003723	molecular_function	RNA binding
B1	0003729	molecular_function	mRNA binding
B1	0005515	molecular_function	protein binding
B1	0005634	cellular_component	nucleus
B1	0005654	cellular_component	nucleoplasm
B1	0005681	cellular_component	spliceosomal complex
B1	0005684	cellular_component	U2-type spliceosomal complex
B1	0005686	cellular_component	U2 snRNP
B1	0005689	cellular_component	U12-type spliceosomal complex
B1	0005730	cellular_component	nucleolus
B1	0006338	biological_process	chromatin remodeling
B1	0006397	biological_process	mRNA processing
B1	0008380	biological_process	RNA splicing
B1	0016607	cellular_component	nuclear speck
B1	0034693	cellular_component	U11/U12 snRNP
B1	0045943	biological_process	positive regulation of transcription by RNA polymerase I
B1	0045944	biological_process	positive regulation of transcription by RNA polymerase II
B1	0045945	biological_process	positive regulation of transcription by RNA polymerase III
B1	0071004	cellular_component	U2-type prespliceosome
B1	0071005	cellular_component	U2-type precatalytic spliceosome
B1	0071013	cellular_component	catalytic step 2 spliceosome
B1	0110016	cellular_component	B-WICH complex
B1	1903241	biological_process	U2-type prespliceosome assembly
B1	1990935	molecular_function	splicing factor binding
B2	0000398	biological_process	mRNA splicing, via spliceosome
B2	0003723	molecular_function	RNA binding
B2	0005515	molecular_function	protein binding
B2	0005634	cellular_component	nucleus
B2	0005654	cellular_component	nucleoplasm
B2	0005681	cellular_component	spliceosomal complex
B2	0005684	cellular_component	U2-type spliceosomal complex
B2	0005686	cellular_component	U2 snRNP
B2	0005689	cellular_component	U12-type spliceosomal complex
B2	0006397	biological_process	mRNA processing
B2	0008380	biological_process	RNA splicing
B2	0016607	cellular_component	nuclear speck
B2	0071005	cellular_component	U2-type precatalytic spliceosome
B2	0071011	cellular_component	precatalytic spliceosome
B2	0071013	cellular_component	catalytic step 2 spliceosome
B2	1903241	biological_process	U2-type prespliceosome assembly
B3	0000124	cellular_component	SAGA complex
B3	0000375	biological_process	RNA splicing, via transesterification reactions
B3	0000398	biological_process	mRNA splicing, via spliceosome
B3	0003676	molecular_function	nucleic acid binding
B3	0005515	molecular_function	protein binding
B3	0005634	cellular_component	nucleus
B3	0005654	cellular_component	nucleoplasm
B3	0005681	cellular_component	spliceosomal complex
B3	0005684	cellular_component	U2-type spliceosomal complex
B3	0005686	cellular_component	U2 snRNP
B3	0005689	cellular_component	U12-type spliceosomal complex
B3	0005730	cellular_component	nucleolus
B3	0006282	biological_process	regulation of DNA repair
B3	0006397	biological_process	mRNA processing
B3	0008380	biological_process	RNA splicing
B3	0030620	molecular_function	U2 snRNA binding
B3	0042177	biological_process	negative regulation of protein catabolic process
B3	0043484	biological_process	regulation of RNA splicing
B3	0044877	molecular_function	protein-containing complex binding
B3	0045893	biological_process	positive regulation of DNA-templated transcription
B3	0071005	cellular_component	U2-type precatalytic spliceosome
B3	0071013	cellular_component	catalytic step 2 spliceosome
B3	1903241	biological_process	U2-type prespliceosome assembly
B4	0000375	biological_process	RNA splicing, via transesterification reactions
B4	0000398	biological_process	mRNA splicing, via spliceosome
B4	0003676	molecular_function	nucleic acid binding
B4	0003723	molecular_function	RNA binding
B4	0005515	molecular_function	protein binding
B4	0005634	cellular_component	nucleus
B4	0005654	cellular_component	nucleoplasm
B4	0005681	cellular_component	spliceosomal complex
B4	0005684	cellular_component	U2-type spliceosomal complex
B4	0005686	cellular_component	U2 snRNP
B4	0005689	cellular_component	U12-type spliceosomal complex
B4	0006397	biological_process	mRNA processing
B4	0008380	biological_process	RNA splicing
B4	0071005	cellular_component	U2-type precatalytic spliceosome
B4	0071011	cellular_component	precatalytic spliceosome
B4	1903241	biological_process	U2-type prespliceosome assembly
B4	1990935	molecular_function	splicing factor binding
B5	0000124	cellular_component	SAGA complex
B5	0000398	biological_process	mRNA splicing, via spliceosome
B5	0003723	molecular_function	RNA binding
B5	0005515	molecular_function	protein binding
B5	0005634	cellular_component	nucleus
B5	0005654	cellular_component	nucleoplasm
B5	0005681	cellular_component	spliceosomal complex
B5	0005684	cellular_component	U2-type spliceosomal complex
B5	0005686	cellular_component	U2 snRNP
B5	0005689	cellular_component	U12-type spliceosomal complex
B5	0006282	biological_process	regulation of DNA repair
B5	0006397	biological_process	mRNA processing
B5	0008380	biological_process	RNA splicing
B5	0043484	biological_process	regulation of RNA splicing
B5	0045893	biological_process	positive regulation of DNA-templated transcription
B5	0071005	cellular_component	U2-type precatalytic spliceosome
B5	0071011	cellular_component	precatalytic spliceosome
B5	1903241	biological_process	U2-type prespliceosome assembly
B5	1990935	molecular_function	splicing factor binding
B6	0000398	biological_process	mRNA splicing, via spliceosome
B6	0001825	biological_process	blastocyst formation
B6	0003676	molecular_function	nucleic acid binding
B6	0003723	molecular_function	RNA binding
B6	0003729	molecular_function	mRNA binding
B6	0005515	molecular_function	protein binding
B6	0005634	cellular_component	nucleus
B6	0005654	cellular_component	nucleoplasm
B6	0005681	cellular_component	spliceosomal complex
B6	0005684	cellular_component	U2-type spliceosomal complex
B6	0005686	cellular_component	U2 snRNP
B6	0005689	cellular_component	U12-type spliceosomal complex
B6	0006397	biological_process	mRNA processing
B6	0008380	biological_process	RNA splicing
B6	0071011	cellular_component	precatalytic spliceosome
B6	0071013	cellular_component	catalytic step 2 spliceosome
B6	1903241	biological_process	U2-type prespliceosome assembly
BP	0000398	biological_process	mRNA splicing, via spliceosome
BP	0003677	molecular_function	DNA binding
BP	0003723	molecular_function	RNA binding
BP	0005515	molecular_function	protein binding
BP	0005634	cellular_component	nucleus
BP	0005654	cellular_component	nucleoplasm
BP	0005681	cellular_component	spliceosomal complex
BP	0005684	cellular_component	U2-type spliceosomal complex
BP	0005686	cellular_component	U2 snRNP
BP	0005689	cellular_component	U12-type spliceosomal complex
BP	0006397	biological_process	mRNA processing
BP	0008270	molecular_function	zinc ion binding
BP	0008380	biological_process	RNA splicing
BP	0016363	cellular_component	nuclear matrix
BP	0016607	cellular_component	nuclear speck
BP	0045893	biological_process	positive regulation of DNA-templated transcription
BP	0046872	molecular_function	metal ion binding
BP	0048863	biological_process	stem cell differentiation
BP	0071005	cellular_component	U2-type precatalytic spliceosome
BP	0071011	cellular_component	precatalytic spliceosome
BP	1903241	biological_process	U2-type prespliceosome assembly
C	0000398	biological_process	mRNA splicing, via spliceosome
C	0003723	molecular_function	RNA binding
C	0003924	molecular_function	GTPase activity
C	0005515	molecular_function	protein binding
C	0005525	molecular_function	GTP binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005681	cellular_component	spliceosomal complex
C	0005829	cellular_component	cytosol
C	0006397	biological_process	mRNA processing
C	0008380	biological_process	RNA splicing
C	0015030	cellular_component	Cajal body
C	0016020	cellular_component	membrane
C	0016607	cellular_component	nuclear speck
C	0030623	molecular_function	U5 snRNA binding
C	0042220	biological_process	response to cocaine
C	0043231	cellular_component	intracellular membrane-bounded organelle
C	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
C	0071005	cellular_component	U2-type precatalytic spliceosome
C	0071007	cellular_component	U2-type catalytic step 2 spliceosome
C	0071013	cellular_component	catalytic step 2 spliceosome
C	0071466	biological_process	cellular response to xenobiotic stimulus
D	0000245	biological_process	spliceosomal complex assembly
D	0000375	biological_process	RNA splicing, via transesterification reactions
D	0000398	biological_process	mRNA splicing, via spliceosome
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005681	cellular_component	spliceosomal complex
D	0005682	cellular_component	U5 snRNP
D	0005829	cellular_component	cytosol
D	0006397	biological_process	mRNA processing
D	0008380	biological_process	RNA splicing
D	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
D	0051301	biological_process	cell division
D	0071005	cellular_component	U2-type precatalytic spliceosome
E	0000375	biological_process	RNA splicing, via transesterification reactions
E	0000398	biological_process	mRNA splicing, via spliceosome
E	0003723	molecular_function	RNA binding
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005681	cellular_component	spliceosomal complex
E	0005682	cellular_component	U5 snRNP
E	0005732	cellular_component	sno(s)RNA-containing ribonucleoprotein complex
E	0005829	cellular_component	cytosol
E	0006396	biological_process	RNA processing
E	0006397	biological_process	mRNA processing
E	0008380	biological_process	RNA splicing
E	0016607	cellular_component	nuclear speck
E	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
E	0071007	cellular_component	U2-type catalytic step 2 spliceosome
E	0071013	cellular_component	catalytic step 2 spliceosome
F	0000375	biological_process	RNA splicing, via transesterification reactions
F	0000398	biological_process	mRNA splicing, via spliceosome
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005681	cellular_component	spliceosomal complex
F	0006396	biological_process	RNA processing
F	0006397	biological_process	mRNA processing
F	0008380	biological_process	RNA splicing
F	0015030	cellular_component	Cajal body
F	0016607	cellular_component	nuclear speck
F	0017070	molecular_function	U6 snRNA binding
F	0030621	molecular_function	U4 snRNA binding
F	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
F	0071001	cellular_component	U4/U6 snRNP
F	0071005	cellular_component	U2-type precatalytic spliceosome
F	0097525	cellular_component	spliceosomal snRNP complex
G	0000245	biological_process	spliceosomal complex assembly
G	0000389	biological_process	mRNA 3'-splice site recognition
G	0000398	biological_process	mRNA splicing, via spliceosome
G	0003676	molecular_function	nucleic acid binding
G	0003723	molecular_function	RNA binding
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005681	cellular_component	spliceosomal complex
G	0005684	cellular_component	U2-type spliceosomal complex
G	0005686	cellular_component	U2 snRNP
G	0006397	biological_process	mRNA processing
G	0008270	molecular_function	zinc ion binding
G	0008380	biological_process	RNA splicing
G	0010976	biological_process	positive regulation of neuron projection development
G	0016607	cellular_component	nuclear speck
G	0046872	molecular_function	metal ion binding
G	0071004	cellular_component	U2-type prespliceosome
G	0071005	cellular_component	U2-type precatalytic spliceosome
G	0071013	cellular_component	catalytic step 2 spliceosome
G	1903241	biological_process	U2-type prespliceosome assembly
H	0000375	biological_process	RNA splicing, via transesterification reactions
H	0000389	biological_process	mRNA 3'-splice site recognition
H	0000398	biological_process	mRNA splicing, via spliceosome
H	0003676	molecular_function	nucleic acid binding
H	0003723	molecular_function	RNA binding
H	0005515	molecular_function	protein binding
H	0005634	cellular_component	nucleus
H	0005654	cellular_component	nucleoplasm
H	0005681	cellular_component	spliceosomal complex
H	0005684	cellular_component	U2-type spliceosomal complex
H	0005686	cellular_component	U2 snRNP
H	0006397	biological_process	mRNA processing
H	0008270	molecular_function	zinc ion binding
H	0008380	biological_process	RNA splicing
H	0016607	cellular_component	nuclear speck
H	0046872	molecular_function	metal ion binding
H	0071005	cellular_component	U2-type precatalytic spliceosome
H	0071013	cellular_component	catalytic step 2 spliceosome
H	1903241	biological_process	U2-type prespliceosome assembly
I	0000398	biological_process	mRNA splicing, via spliceosome
I	0003723	molecular_function	RNA binding
I	0005515	molecular_function	protein binding
I	0005634	cellular_component	nucleus
I	0005654	cellular_component	nucleoplasm
I	0005681	cellular_component	spliceosomal complex
I	0006397	biological_process	mRNA processing
I	0008380	biological_process	RNA splicing
I	0071005	cellular_component	U2-type precatalytic spliceosome
I	0071011	cellular_component	precatalytic spliceosome
J	0000244	biological_process	spliceosomal tri-snRNP complex assembly
J	0000375	biological_process	RNA splicing, via transesterification reactions
J	0000398	biological_process	mRNA splicing, via spliceosome
J	0003723	molecular_function	RNA binding
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005654	cellular_component	nucleoplasm
J	0005681	cellular_component	spliceosomal complex
J	0005829	cellular_component	cytosol
J	0006397	biological_process	mRNA processing
J	0008380	biological_process	RNA splicing
J	0015030	cellular_component	Cajal body
J	0016607	cellular_component	nuclear speck
J	0032991	cellular_component	protein-containing complex
J	0042802	molecular_function	identical protein binding
J	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
J	0071005	cellular_component	U2-type precatalytic spliceosome
K	0000398	biological_process	mRNA splicing, via spliceosome
K	0001527	cellular_component	microfibril
K	0003723	molecular_function	RNA binding
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0005654	cellular_component	nucleoplasm
K	0005681	cellular_component	spliceosomal complex
K	0005684	cellular_component	U2-type spliceosomal complex
K	0005813	cellular_component	centrosome
K	0006397	biological_process	mRNA processing
K	0008380	biological_process	RNA splicing
K	0071005	cellular_component	U2-type precatalytic spliceosome
L	0000244	biological_process	spliceosomal tri-snRNP complex assembly
L	0000398	biological_process	mRNA splicing, via spliceosome
L	0003723	molecular_function	RNA binding
L	0005515	molecular_function	protein binding
L	0005634	cellular_component	nucleus
L	0005654	cellular_component	nucleoplasm
L	0005681	cellular_component	spliceosomal complex
L	0005684	cellular_component	U2-type spliceosomal complex
L	0005687	cellular_component	U4 snRNP
L	0005690	cellular_component	U4atac snRNP
L	0006397	biological_process	mRNA processing
L	0008380	biological_process	RNA splicing
L	0015030	cellular_component	Cajal body
L	0016607	cellular_component	nuclear speck
L	0030621	molecular_function	U4 snRNA binding
L	0030622	molecular_function	U4atac snRNA binding
L	0030674	molecular_function	protein-macromolecule adaptor activity
L	0042802	molecular_function	identical protein binding
L	0043021	molecular_function	ribonucleoprotein complex binding
L	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
L	0048254	biological_process	snoRNA localization
L	0070990	molecular_function	snRNP binding
L	0071005	cellular_component	U2-type precatalytic spliceosome
L	0071011	cellular_component	precatalytic spliceosome
L	0071166	biological_process	ribonucleoprotein complex localization
L	0071339	cellular_component	MLL1 complex
L	0097526	cellular_component	spliceosomal tri-snRNP complex
M	0000398	biological_process	mRNA splicing, via spliceosome
M	0001651	cellular_component	dense fibrillar component
M	0003723	molecular_function	RNA binding
M	0005515	molecular_function	protein binding
M	0005634	cellular_component	nucleus
M	0005654	cellular_component	nucleoplasm
M	0005681	cellular_component	spliceosomal complex
M	0005690	cellular_component	U4atac snRNP
M	0005730	cellular_component	nucleolus
M	0006397	biological_process	mRNA processing
M	0008380	biological_process	RNA splicing
M	0030490	biological_process	maturation of SSU-rRNA
M	0030515	molecular_function	snoRNA binding
M	0030621	molecular_function	U4 snRNA binding
M	0030622	molecular_function	U4atac snRNA binding
M	0031428	cellular_component	box C/D methylation guide snoRNP complex
M	0032040	cellular_component	small-subunit processome
M	0032991	cellular_component	protein-containing complex
M	0034511	molecular_function	U3 snoRNA binding
M	0034512	molecular_function	box C/D sno(s)RNA binding
M	0042254	biological_process	ribosome biogenesis
M	0042274	biological_process	ribosomal small subunit biogenesis
M	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
M	0051117	molecular_function	ATPase binding
M	0071005	cellular_component	U2-type precatalytic spliceosome
M	0071011	cellular_component	precatalytic spliceosome
M	1990904	cellular_component	ribonucleoprotein complex
N	0000244	biological_process	spliceosomal tri-snRNP complex assembly
N	0000245	biological_process	spliceosomal complex assembly
N	0000375	biological_process	RNA splicing, via transesterification reactions
N	0000398	biological_process	mRNA splicing, via spliceosome
N	0003723	molecular_function	RNA binding
N	0005515	molecular_function	protein binding
N	0005634	cellular_component	nucleus
N	0005654	cellular_component	nucleoplasm
N	0005681	cellular_component	spliceosomal complex
N	0005682	cellular_component	U5 snRNP
N	0006396	biological_process	RNA processing
N	0006397	biological_process	mRNA processing
N	0006403	biological_process	RNA localization
N	0008380	biological_process	RNA splicing
N	0016020	cellular_component	membrane
N	0016607	cellular_component	nuclear speck
N	0030674	molecular_function	protein-macromolecule adaptor activity
N	0042802	molecular_function	identical protein binding
N	0043021	molecular_function	ribonucleoprotein complex binding
N	0045944	biological_process	positive regulation of transcription by RNA polymerase II
N	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
N	0071005	cellular_component	U2-type precatalytic spliceosome
N	0071013	cellular_component	catalytic step 2 spliceosome
Q	0000398	biological_process	mRNA splicing, via spliceosome
Q	0000785	cellular_component	chromatin
Q	0005515	molecular_function	protein binding
Q	0005634	cellular_component	nucleus
Q	0005654	cellular_component	nucleoplasm
Q	0005681	cellular_component	spliceosomal complex
Q	0006397	biological_process	mRNA processing
Q	0008380	biological_process	RNA splicing
Q	0016922	molecular_function	nuclear receptor binding
Q	0030374	molecular_function	nuclear receptor coactivator activity
Q	0045893	biological_process	positive regulation of DNA-templated transcription
Q	0071007	cellular_component	U2-type catalytic step 2 spliceosome
Q	2000825	biological_process	positive regulation of androgen receptor activity
S	0000387	biological_process	spliceosomal snRNP assembly
S	0000398	biological_process	mRNA splicing, via spliceosome
S	0000481	biological_process	maturation of 5S rRNA
S	0003723	molecular_function	RNA binding
S	0005515	molecular_function	protein binding
S	0005634	cellular_component	nucleus
S	0005654	cellular_component	nucleoplasm
S	0005681	cellular_component	spliceosomal complex
S	0005737	cellular_component	cytoplasm
S	0005794	cellular_component	Golgi apparatus
S	0005829	cellular_component	cytosol
S	0006397	biological_process	mRNA processing
S	0008380	biological_process	RNA splicing
S	0015030	cellular_component	Cajal body
S	0016607	cellular_component	nuclear speck
S	0045292	biological_process	mRNA cis splicing, via spliceosome
S	0045585	biological_process	positive regulation of cytotoxic T cell differentiation
S	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
S	0071005	cellular_component	U2-type precatalytic spliceosome
S	0071013	cellular_component	catalytic step 2 spliceosome
T	0000122	biological_process	negative regulation of transcription by RNA polymerase II
T	0003711	molecular_function	transcription elongation factor activity
T	0003712	molecular_function	transcription coregulator activity
T	0003713	molecular_function	transcription coactivator activity
T	0003714	molecular_function	transcription corepressor activity
T	0003723	molecular_function	RNA binding
T	0005515	molecular_function	protein binding
T	0005634	cellular_component	nucleus
T	0005654	cellular_component	nucleoplasm
T	0006397	biological_process	mRNA processing
T	0008380	biological_process	RNA splicing
T	0016607	cellular_component	nuclear speck
T	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
T	0034244	biological_process	negative regulation of transcription elongation by RNA polymerase II
T	0042802	molecular_function	identical protein binding
T	0044390	molecular_function	ubiquitin-like protein conjugating enzyme binding
T	0045944	biological_process	positive regulation of transcription by RNA polymerase II
T	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
T	0070063	molecular_function	RNA polymerase binding
W	0000398	biological_process	mRNA splicing, via spliceosome
W	0000413	biological_process	protein peptidyl-prolyl isomerization
W	0003755	molecular_function	peptidyl-prolyl cis-trans isomerase activity
W	0005515	molecular_function	protein binding
W	0005634	cellular_component	nucleus
W	0005654	cellular_component	nucleoplasm
W	0005681	cellular_component	spliceosomal complex
W	0005737	cellular_component	cytoplasm
W	0005829	cellular_component	cytosol
W	0006357	biological_process	regulation of transcription by RNA polymerase II
W	0006397	biological_process	mRNA processing
W	0006457	biological_process	protein folding
W	0008380	biological_process	RNA splicing
W	0016018	molecular_function	cyclosporin A binding
W	0016607	cellular_component	nuclear speck
W	0043021	molecular_function	ribonucleoprotein complex binding
W	0043231	cellular_component	intracellular membrane-bounded organelle
W	0045070	biological_process	positive regulation of viral genome replication
W	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
W	0065003	biological_process	protein-containing complex assembly
W	0071001	cellular_component	U4/U6 snRNP
W	0140839	molecular_function	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity
W	0140840	molecular_function	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity
X	0000398	biological_process	mRNA splicing, via spliceosome
X	0003676	molecular_function	nucleic acid binding
X	0003723	molecular_function	RNA binding
X	0005515	molecular_function	protein binding
X	0005634	cellular_component	nucleus
X	0005654	cellular_component	nucleoplasm
X	0005681	cellular_component	spliceosomal complex
X	0006397	biological_process	mRNA processing
X	0008270	molecular_function	zinc ion binding
X	0008380	biological_process	RNA splicing
X	0016607	cellular_component	nuclear speck
X	0045292	biological_process	mRNA cis splicing, via spliceosome
X	0046872	molecular_function	metal ion binding
X	0070064	molecular_function	proline-rich region binding
X	0071005	cellular_component	U2-type precatalytic spliceosome
X	0071011	cellular_component	precatalytic spliceosome
r	0000398	biological_process	mRNA splicing, via spliceosome
r	0003676	molecular_function	nucleic acid binding
r	0003677	molecular_function	DNA binding
r	0005515	molecular_function	protein binding
r	0005634	cellular_component	nucleus
r	0005654	cellular_component	nucleoplasm
r	0005681	cellular_component	spliceosomal complex
r	0006397	biological_process	mRNA processing
r	0008270	molecular_function	zinc ion binding
r	0008380	biological_process	RNA splicing
r	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
r	0046872	molecular_function	metal ion binding
r	0071005	cellular_component	U2-type precatalytic spliceosome
s	0000398	biological_process	mRNA splicing, via spliceosome
s	0005515	molecular_function	protein binding
s	0005634	cellular_component	nucleus
s	0005654	cellular_component	nucleoplasm
s	0005737	cellular_component	cytoplasm
s	0015030	cellular_component	Cajal body
s	0031386	molecular_function	protein tag activity
s	0036211	biological_process	protein modification process
s	1903955	biological_process	positive regulation of protein targeting to mitochondrion
v	0000381	biological_process	regulation of alternative mRNA splicing, via spliceosome
v	0000398	biological_process	mRNA splicing, via spliceosome
v	0005515	molecular_function	protein binding
v	0005634	cellular_component	nucleus
v	0005654	cellular_component	nucleoplasm
v	0005737	cellular_component	cytoplasm
v	0006397	biological_process	mRNA processing
v	0008380	biological_process	RNA splicing
v	0016607	cellular_component	nuclear speck
v	0071005	cellular_component	U2-type precatalytic spliceosome
v	0071011	cellular_component	precatalytic spliceosome
w	0000381	biological_process	regulation of alternative mRNA splicing, via spliceosome
w	0000398	biological_process	mRNA splicing, via spliceosome
w	0005515	molecular_function	protein binding
w	0005634	cellular_component	nucleus
w	0005654	cellular_component	nucleoplasm
w	0005737	cellular_component	cytoplasm
w	0006397	biological_process	mRNA processing
w	0008380	biological_process	RNA splicing
w	0016607	cellular_component	nuclear speck
w	0071005	cellular_component	U2-type precatalytic spliceosome
w	0071011	cellular_component	precatalytic spliceosome
x	0000228	cellular_component	nuclear chromosome
x	0000278	biological_process	mitotic cell cycle
x	0000398	biological_process	mRNA splicing, via spliceosome
x	0000922	cellular_component	spindle pole
x	0005515	molecular_function	protein binding
x	0005634	cellular_component	nucleus
x	0005654	cellular_component	nucleoplasm
x	0005681	cellular_component	spliceosomal complex
x	0005694	cellular_component	chromosome
x	0005737	cellular_component	cytoplasm
x	0005856	cellular_component	cytoskeleton
x	0006397	biological_process	mRNA processing
x	0007094	biological_process	mitotic spindle assembly checkpoint signaling
x	0008380	biological_process	RNA splicing
x	0016607	cellular_component	nuclear speck
x	0034501	biological_process	protein localization to kinetochore
x	0042802	molecular_function	identical protein binding
x	0071005	cellular_component	U2-type precatalytic spliceosome
x	0097431	cellular_component	mitotic spindle pole
y	0000228	cellular_component	nuclear chromosome
y	0000278	biological_process	mitotic cell cycle
y	0000398	biological_process	mRNA splicing, via spliceosome
y	0000922	cellular_component	spindle pole
y	0005515	molecular_function	protein binding
y	0005634	cellular_component	nucleus
y	0005654	cellular_component	nucleoplasm
y	0005681	cellular_component	spliceosomal complex
y	0005694	cellular_component	chromosome
y	0005737	cellular_component	cytoplasm
y	0005856	cellular_component	cytoskeleton
y	0006397	biological_process	mRNA processing
y	0007094	biological_process	mitotic spindle assembly checkpoint signaling
y	0008380	biological_process	RNA splicing
y	0016607	cellular_component	nuclear speck
y	0034501	biological_process	protein localization to kinetochore
y	0042802	molecular_function	identical protein binding
y	0071005	cellular_component	U2-type precatalytic spliceosome
y	0097431	cellular_component	mitotic spindle pole
z	0000380	biological_process	alternative mRNA splicing, via spliceosome
z	0000395	biological_process	mRNA 5'-splice site recognition
z	0000398	biological_process	mRNA splicing, via spliceosome
z	0003676	molecular_function	nucleic acid binding
z	0003723	molecular_function	RNA binding
z	0003729	molecular_function	mRNA binding
z	0005515	molecular_function	protein binding
z	0005634	cellular_component	nucleus
z	0005635	cellular_component	nuclear envelope
z	0005654	cellular_component	nucleoplasm
z	0005681	cellular_component	spliceosomal complex
z	0005737	cellular_component	cytoplasm
z	0006376	biological_process	mRNA splice site recognition
z	0006397	biological_process	mRNA processing
z	0008380	biological_process	RNA splicing
z	0016607	cellular_component	nuclear speck
z	0033120	biological_process	positive regulation of RNA splicing
z	0035145	cellular_component	exon-exon junction complex
z	0043422	molecular_function	protein kinase B binding
z	0043484	biological_process	regulation of RNA splicing
z	0044547	molecular_function	DNA topoisomerase binding
z	0048709	biological_process	oligodendrocyte differentiation
z	0051028	biological_process	mRNA transport
z	0071013	cellular_component	catalytic step 2 spliceosome
z	0097421	biological_process	liver regeneration

Functional Information from PROSITE/UniProt

site_id	PS00028
Number of Residues	23
Details	ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. Cnv..CdcvVkdsinfldHingkkH

Chain	Residue	Details
r	CYS82-HIS104

---

site_id	PS00170
Number of Residues	18
Details	CSA_PPIASE_1 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. YkgStFHRVIkdFMiQGG

Chain	Residue	Details
W	TYR60-GLY77

---

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. FVCSATH

Chain	Residue	Details
B3	PHE287-HIS293

---

site_id	PS00436
Number of Residues	12
Details	PEROXIDASE_2 Peroxidases active site signature. TVrvARVmWHPS

Chain	Residue	Details
F	THR323-SER334

---

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. LASAgfDrLILLWNV

Chain	Residue	Details
E	LEU81-VAL95
E	LEU124-SER138
E	VAL167-ILE181
E	ILE208-LEU222
E	ILE300-THR314
F	LEU338-LEU352
F	ILE422-LEU436
v	LEU229-PHE243
v	ILE364-MET378

---

site_id	PS00997
Number of Residues	23
Details	G10_1 G10 protein signature 1. LCClRCiqtrDtNfgtnCiCRVP

Chain	Residue	Details
Q	LEU100-PRO122

---

site_id	PS00998
Number of Residues	10
Details	G10_2 G10 protein signature 2. CtHCGCRGCS

Chain	Residue	Details
Q	CYS134-SER143

---

site_id	PS01082
Number of Residues	18
Details	RIBOSOMAL_L7AE Ribosomal protein L7Ae signature. CedknVPYvfVrSKqaLG

Chain	Residue	Details
M	CYS73-GLY90

---

site_id	PS01159
Number of Residues	26
Details	WW_DOMAIN_1 WW/rsp5/WWP domain signature. WteyktadgktyYYnnrtle.STWEKP

Chain	Residue	Details
T	TRP435-PRO460
X	TRP128-PRO153
X	TRP169-PRO194

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q9Z315

Chain	Residue	Details
S	THR189
BP	CYS72
BP	CYS75
BP	CYS85
I	SER226
B2	ARG247
B2	ARG515
B1	LEU1141
BP	CYS46
BP	CYS49
BP	CYS58
BP	CYS61

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
S	SER321
S	SER348
S	SER761
S	SER789

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163

Chain	Residue	Details
S	THR392
X	SER229
z	ARG109
y	SER287
y	SER417
y	SER536
r	LYS70
r	LYS102
r	LYS123

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:17525332, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163

Chain	Residue	Details
S	THR430
K	SER361
K	SER432
22	LYS6
22	LYS8
42	LYS6
42	LYS8

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18220336, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
S	SER448
B2	SER309
9	SER369
H	SER365
H	SER367
H	SER369

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
S	SER474
x	LYS501
x	LYS509
x	LYS541
x	LYS543
x	LYS553
y	LYS151
y	LYS310
y	LYS331
y	LYS386
S	SER621
y	LYS388
y	LYS404
y	LYS408
y	LYS496
y	LYS501
y	LYS509
y	LYS541
y	LYS543
y	LYS553
x	LYS310
x	LYS331
x	LYS386
x	LYS388
x	LYS404
x	LYS408
x	LYS496

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648

Chain	Residue	Details
S	SER486
B2	SER861

---

site_id	SWS_FT_FI8
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231

Chain	Residue	Details
S	SER521
S	SER596
S	SER598

---

site_id	SWS_FT_FI9
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:20068231

Chain	Residue	Details
S	SER591
B2	SER435
B2	SER436

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:17525332

Chain	Residue	Details
S	THR695
7	LYS131
K	LYS357
K	LYS371
K	LYS381
K	LYS415
K	LYS418

---

site_id	SWS_FT_FI11
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:19690332

Chain	Residue	Details
S	THR764
z	SER209
L	LYS478

---

site_id	SWS_FT_FI12
Number of Residues	20
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
S	LYS125
S	LYS648
S	LYS657
S	LYS684
S	LYS699
S	LYS709
S	LYS723
S	LYS749
S	LYS758
S	LYS775
S	LYS780
z	SER234
S	LYS791
S	LYS133
S	LYS277
S	LYS329
S	LYS336
S	LYS400
S	LYS414
S	LYS548

---

site_id	SWS_FT_FI13
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:25114211, ECO:0007744|PubMed:25218447, ECO:0007744|PubMed:25755297, ECO:0007744|PubMed:25772364, ECO:0007744|PubMed:28112733

Chain	Residue	Details
S	LYS141

---

site_id	SWS_FT_FI14
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:25218447, ECO:0007744|PubMed:25755297, ECO:0007744|PubMed:25772364, ECO:0007744|PubMed:28112733

Chain	Residue	Details
S	LYS147
S	LYS188

---

site_id	SWS_FT_FI15
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163

Chain	Residue	Details
B1	THR227

---

site_id	SWS_FT_FI16
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q99NB9

Chain	Residue	Details
B1	SER229

---

site_id	SWS_FT_FI17
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0000269|PubMed:12105215

Chain	Residue	Details
B1	THR244

---

site_id	SWS_FT_FI18
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0000305|PubMed:12105215

Chain	Residue	Details
B1	THR248

---

site_id	SWS_FT_FI19
Number of Residues	5
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
B1	THR257
B1	THR261
B1	THR278
B1	THR303
B1	THR313

---

site_id	SWS_FT_FI20
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18220336, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
B1	THR267

---

site_id	SWS_FT_FI21
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
B1	THR273

---

site_id	SWS_FT_FI22
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
B1	SER287

---

site_id	SWS_FT_FI23
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:23186163

Chain	Residue	Details
B1	THR296

---

site_id	SWS_FT_FI24
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:17081983

Chain	Residue	Details
B1	THR299

---

site_id	SWS_FT_FI25
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
B1	SER322

---

site_id	SWS_FT_FI26
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
B1	THR326

---

site_id	SWS_FT_FI27
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231

Chain	Residue	Details
B1	THR328

---

site_id	SWS_FT_FI28
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163

Chain	Residue	Details
B1	SER332

---

site_id	SWS_FT_FI29
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:21406692

Chain	Residue	Details
B1	THR341

---

site_id	SWS_FT_FI30
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692

Chain	Residue	Details
B1	SER344

---

site_id	SWS_FT_FI31
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:21406692

Chain	Residue	Details
B1	SER349

---

site_id	SWS_FT_FI32
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163

Chain	Residue	Details
B1	THR350
B1	THR436

---

site_id	SWS_FT_FI33
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18691976, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
B1	THR354

---

site_id	SWS_FT_FI34
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163

Chain	Residue	Details
B1	SER400

---

site_id	SWS_FT_FI35
Number of Residues	1
Details	MOD_RES: Phosphothreonine; by DYRK1A => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163

Chain	Residue	Details
B1	THR434

---

site_id	SWS_FT_FI36
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
B1	SER488

---

site_id	SWS_FT_FI37
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:28112733

Chain	Residue	Details
B1	LYS214

---

site_id	SWS_FT_FI38
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
B1	LYS430

---

site_id	SWS_FT_FI39
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:25114211, ECO:0007744|PubMed:25218447, ECO:0007744|PubMed:25755297, ECO:0007744|PubMed:28112733

Chain	Residue	Details
B1	LYS413

---